4-Methylfuran-2-carbaldehyde

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  • Identifiers

    CAS number
    33342-49-3

    Molecular formula
    C6H6O2

    SMILES
    CC1=COC(=C1)C=O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 82.27%
    Caramellic 67.55%
    Nutty 57.95%
    Spicy 55.56%
    Almond 55.44%
    Coumarinic 40.38%
    Fruity 39.43%
    Hay 37.78%
    Burnt 37.27%
    Cherry 35.44%

     

    Flavor
    Sweet 64.27%
    Almond 60.22%
    Woody 60.12%
    Caramel 50.69%
    Spice 42.69%
    Cherry 35.65%
    Tobacco 32.17%
    Bread 30.38%
    Musty 28.64%
    Creamy 27.82%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.1

    pKa est.
    5.58 (weak acid)

    Molecular weight
    110.11 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Boiling point est.
    195°C

    Flash point

    • 43.65 ˚C est.

  • Synonyms

    • 4-methylfuran-2-carbaldehyde
    • 33342-49-3
    • RefChem:525588
    • 898-531-3
    • 4-methyl-2-furfural
    • MFCD15143710
    • 2-Furancarboxaldehyde, 4-methyl-
    • 4-methyl-2-furaldehyde
    • 4-methylfurfural
    • SCHEMBL182957
    • SCHEMBL22371862
    • BLHZUMDWLLFLJC-UHFFFAOYSA-N
    • DTXSID501377045
    • AKOS022632683
    • SB11578
    • AS-51044
    • SY197678
    • DB-358393
    • CS-0055543
    • EN300-92084
    • P11782
    • F502332
    • Z1255374618
    • 33342-49-3

  • Applications

    4-Methylfuran-2-carbaldehyde (CAS 33342-49-3) is primarily used as an organic-synthesis intermediate and building block in fragrance and flavor chemistry. In perfumery and flavor applications, it is evaluated as an odorant precursor and contributes to specific aroma profiles. In cosmetics and personal care, it may serve as a fragrance ingredient or intermediate in scent formulations. In household products such as cleaners and air fresheners, it can be used to impart or stabilize characteristic notes. In industrial manufacturing, it acts as a versatile precursor for heterocyclic compounds and other specialty chemicals, including derivatives for polymers and materials. It may also be encountered as a reactive intermediate in research and development for pharmaceuticals or agrochemicals, depending on regional regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 621.26
    methanol 1090.16
    isopropanol 353.33
    water 28.12
    ethyl acetate 374.14
    n-propanol 333.67
    acetone 525.4
    n-butanol 321.2
    acetonitrile 454.67
    DMF 799.33
    toluene 125.65
    isobutanol 232.81
    1,4-dioxane 531.36
    methyl acetate 418.47
    THF 534.44
    2-butanone 339.19
    n-pentanol 205.38
    sec-butanol 246.5
    n-hexane 17.44
    ethylene glycol 299.35
    NMP 385.46
    cyclohexane 23.64
    DMSO 557.98
    n-butyl acetate 164.47
    n-octanol 120.05
    chloroform 390.4
    n-propyl acetate 175.52
    acetic acid 531.51
    dichloromethane 445.87
    cyclohexanone 245.1
    propylene glycol 197.59
    isopropyl acetate 170.67
    DMAc 482.62
    2-ethoxyethanol 466.74
    isopentanol 256.93
    n-heptane 24.39
    ethyl formate 264.21
    1,2-dichloroethane 297.75
    n-hexanol 204.9
    2-methoxyethanol 873.81
    isobutyl acetate 103.43
    tetrachloromethane 77.4
    n-pentyl acetate 91.36
    transcutol 1009.23
    n-heptanol 97.07
    ethylbenzene 71.92
    MIBK 179.51
    2-propoxyethanol 407.31
    tert-butanol 427.66
    MTBE 274.25
    2-butoxyethanol 197.04
    propionic acid 272.39
    o-xylene 92.45
    formic acid 466.28
    diethyl ether 309.92
    m-xylene 98.83
    p-xylene 87.73
    chlorobenzene 142.16
    dimethyl carbonate 169.45
    n-octane 11.96
    formamide 537.08
    cyclopentanone 300.63
    2-pentanone 276.62
    anisole 211.73
    cyclopentyl methyl ether 219.35
    gamma-butyrolactone 355.51
    1-methoxy-2-propanol 493.09
    pyridine 275.08
    3-pentanone 186.72
    furfural 392.77
    n-dodecane 12.95
    diethylene glycol 461.78
    diisopropyl ether 83.39
    tert-amyl alcohol 294.47
    acetylacetone 304.34
    n-hexadecane 14.2
    acetophenone 164.53
    methyl propionate 275.1
    isopentyl acetate 146.19
    trichloroethylene 496.13
    n-nonanol 100.31
    cyclohexanol 164.2
    benzyl alcohol 173.25
    2-ethylhexanol 113.65
    isooctanol 80.14
    dipropyl ether 119.75
    1,2-dichlorobenzene 133.89
    ethyl lactate 118.35
    propylene carbonate 199.54
    n-methylformamide 486.48
    2-pentanol 193.07
    n-pentane 24.24
    1-propoxy-2-propanol 248.79
    1-methoxy-2-propyl acetate 194.34
    2-(2-methoxypropoxy) propanol 226.52
    mesitylene 66.55
    ε-caprolactone 219.83
    p-cymene 57.67
    epichlorohydrin 451.77
    1,1,1-trichloroethane 267.16
    2-aminoethanol 347.23
    morpholine-4-carbaldehyde 540.21
    sulfolane 341.7
    2,2,4-trimethylpentane 21.09
    2-methyltetrahydrofuran 341.96
    n-hexyl acetate 154.28
    isooctane 19.52
    2-(2-butoxyethoxy)ethanol 294.45
    sec-butyl acetate 113.94
    tert-butyl acetate 195.01
    decalin 21.18
    glycerin 304.61
    diglyme 517.18
    acrylic acid 281.69
    isopropyl myristate 72.01
    n-butyric acid 311.55
    acetyl acetate 193.67
    di(2-ethylhexyl) phthalate 71.62
    ethyl propionate 153.52
    nitromethane 806.31
    1,2-diethoxyethane 243.32
    benzonitrile 167.44
    trioctyl phosphate 53.28
    1-bromopropane 171.85
    gamma-valerolactone 415.35
    n-decanol 78.89
    triethyl phosphate 70.6
    4-methyl-2-pentanol 124.87
    propionitrile 270.98
    vinylene carbonate 200.66
    1,1,2-trichlorotrifluoroethane 335.55
    DMS 152.3
    cumene 56.45
    2-octanol 68.37
    2-hexanone 166.42
    octyl acetate 88.2
    limonene 80.22
    1,2-dimethoxyethane 532.18
    ethyl orthosilicate 69.72
    tributyl phosphate 64.98
    diacetone alcohol 273.53
    N,N-dimethylaniline 139.96
    acrylonitrile 345.96
    aniline 169.0
    1,3-propanediol 434.49
    bromobenzene 136.86
    dibromomethane 274.93
    1,1,2,2-tetrachloroethane 298.89
    2-methyl-cyclohexyl acetate 98.3
    tetrabutyl urea 90.14
    diisobutyl methanol 83.57
    2-phenylethanol 156.27
    styrene 91.67
    dioctyl adipate 95.13
    dimethyl sulfate 205.4
    ethyl butyrate 129.02
    methyl lactate 170.75
    butyl lactate 86.04
    diethyl carbonate 101.35
    propanediol butyl ether 202.63
    triethyl orthoformate 92.39
    p-tert-butyltoluene 59.58
    methyl 4-tert-butylbenzoate 140.31
    morpholine 522.22
    tert-butylamine 250.32
    n-dodecanol 63.3
    dimethoxymethane 517.75
    ethylene carbonate 160.93
    cyrene 172.48
    2-ethoxyethyl acetate 153.74
    2-ethylhexyl acetate 107.34
    1,2,4-trichlorobenzene 153.93
    4-methylpyridine 256.17
    dibutyl ether 109.05
    2,6-dimethyl-4-heptanol 83.57
    DEF 316.45
    dimethyl isosorbide 274.44
    tetrachloroethylene 220.96
    eugenol 161.57
    triacetin 152.61
    span 80 145.95
    1,4-butanediol 198.17
    1,1-dichloroethane 298.43
    2-methyl-1-pentanol 172.28
    methyl formate 408.07
    2-methyl-1-butanol 219.63
    n-decane 19.06
    butyronitrile 258.61
    3,7-dimethyl-1-octanol 124.77
    1-chlorooctane 67.23
    1-chlorotetradecane 32.87
    n-nonane 18.36
    undecane 15.25
    tert-butylcyclohexane 23.2
    cyclooctane 11.73
    cyclopentanol 176.77
    tetrahydropyran 301.94
    tert-amyl methyl ether 197.36
    2,5,8-trioxanonane 361.8
    1-hexene 68.11
    2-isopropoxyethanol 284.0
    2,2,2-trifluoroethanol 230.0
    methyl butyrate 199.93

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction