4-Methyl-2,5-diisopropylphenol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    15269-16-6

    Molecular formula
    C13H20O

    SMILES
    CC1=CC(=C(C=C1C(C)C)O)C(C)C

    Safety labels

  • Odor profile

    Fragrance
    Phenolic 73.84%
    Spicy 67.7%
    Woody 52.8%
    Medicinal 51.56%
    Herbal 51.41%
    Smoky 50.66%
    Leathery 49.31%
    Burnt 40.62%
    Camphoreous 36.38%
    Dry 30.23%

     

    Flavor
    Woody 43.47%
    Camphor 39.08%
    Phenolic 38.21%
    Medicinal 37.06%
    Herbal 36.75%
    Spice 36.12%
    Spicy 28.01%
    Musty 25.64%
    Creosote 24.48%
    Thymol 24.3%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    4.2

    pKa est.
    10.39 (weak base)

    Molecular weight
    192.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    270°C

    Melting point expt.

    • 52.7 °C

    Flash point

    • 124.88 ˚C est.

  • Synonyms

    • 4-Methyl-2,5-diisopropylphenol
    • 15269-16-6
    • 4-methyl-2,5-di(propan-2-yl)phenol
    • 2,5-diisopropyl-4-methylphenol
    • 8W2HFJ50G6
    • UNII-8W2HFJ50G6
    • 4-methyl-2,5-bis(propan-2-yl)phenol
    • SCHEMBL1487434
    • 2,5-Diisopropyl-p-cresol, 8CI
    • DTXSID40165102
    • 2,5-DIISOPROPYL-P-CRESOL
    • UJBZHJNVIHOWFA-UHFFFAOYSA-N
    • P-CRESOL, 2,5-DIISOPROPYL-
    • Phenol, 4-methyl-2,5-bis(1-methylethyl)-
    • 4-Methyl-2,5-bis(1-methylethyl)phenol, 9CI
    • Q27271105
    • 15269-16-6

  • Applications

    For 4-Methyl-2,5-diisopropylphenol (CAS 15269-16-6), practical applications span several industries, primarily as an antioxidant and stabilizer. It may act as an antioxidant/stabilizer in polymers and rubbers to inhibit oxidative degradation; it can function as a stabilizer in coatings and inks; it may be used in lubricants and petroleum products; it may be evaluated for use in cosmetics/personal care formulations as an antioxidant; it may serve as a fragrance ingredient or odorant in perfumery; and it may be employed as an intermediate in chemical synthesis. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1285.82
    methanol 1238.85
    isopropanol 1241.81
    water 0.41
    ethyl acetate 1228.49
    n-propanol 1357.34
    acetone 1788.11
    n-butanol 1262.58
    acetonitrile 1355.78
    DMF 2257.91
    toluene 805.48
    isobutanol 1040.41
    1,4-dioxane 3375.84
    methyl acetate 1067.49
    THF 5257.94
    2-butanone 1533.8
    n-pentanol 825.26
    sec-butanol 988.39
    n-hexane 979.0
    ethylene glycol 87.11
    NMP 1148.9
    cyclohexane 959.41
    DMSO 922.05
    n-butyl acetate 1415.25
    n-octanol 505.89
    chloroform 2351.12
    n-propyl acetate 760.5
    acetic acid 431.95
    dichloromethane 1933.89
    cyclohexanone 2204.26
    propylene glycol 138.14
    isopropyl acetate 823.35
    DMAc 1006.29
    2-ethoxyethanol 652.86
    isopentanol 1048.35
    n-heptane 348.26
    ethyl formate 642.0
    1,2-dichloroethane 2030.11
    n-hexanol 1663.16
    2-methoxyethanol 1131.09
    isobutyl acetate 546.13
    tetrachloromethane 576.87
    n-pentyl acetate 656.5
    transcutol 1105.01
    n-heptanol 578.18
    ethylbenzene 454.7
    MIBK 819.25
    2-propoxyethanol 1541.37
    tert-butanol 1551.8
    MTBE 2492.81
    2-butoxyethanol 646.54
    propionic acid 499.07
    o-xylene 425.24
    formic acid 89.02
    diethyl ether 3090.01
    m-xylene 556.6
    p-xylene 561.64
    chlorobenzene 796.89
    dimethyl carbonate 352.01
    n-octane 171.96
    formamide 194.48
    cyclopentanone 2463.52
    2-pentanone 1444.26
    anisole 635.81
    cyclopentyl methyl ether 2042.42
    gamma-butyrolactone 1991.19
    1-methoxy-2-propanol 927.87
    pyridine 1474.28
    3-pentanone 1118.47
    furfural 913.08
    n-dodecane 84.66
    diethylene glycol 541.78
    diisopropyl ether 823.95
    tert-amyl alcohol 1095.84
    acetylacetone 882.65
    n-hexadecane 100.92
    acetophenone 422.86
    methyl propionate 916.63
    isopentyl acetate 1160.54
    trichloroethylene 2254.59
    n-nonanol 432.06
    cyclohexanol 1123.15
    benzyl alcohol 374.55
    2-ethylhexanol 750.45
    isooctanol 451.01
    dipropyl ether 1233.01
    1,2-dichlorobenzene 564.08
    ethyl lactate 204.73
    propylene carbonate 826.1
    n-methylformamide 813.8
    2-pentanol 919.17
    n-pentane 695.27
    1-propoxy-2-propanol 974.11
    1-methoxy-2-propyl acetate 784.06
    2-(2-methoxypropoxy) propanol 324.04
    mesitylene 369.63
    ε-caprolactone 1385.05
    p-cymene 258.79
    epichlorohydrin 2344.97
    1,1,1-trichloroethane 1666.55
    2-aminoethanol 258.7
    morpholine-4-carbaldehyde 1305.86
    sulfolane 1470.87
    2,2,4-trimethylpentane 184.77
    2-methyltetrahydrofuran 2945.66
    n-hexyl acetate 879.41
    isooctane 175.94
    2-(2-butoxyethoxy)ethanol 555.12
    sec-butyl acetate 491.66
    tert-butyl acetate 895.06
    decalin 272.26
    glycerin 159.31
    diglyme 1088.37
    acrylic acid 311.51
    isopropyl myristate 296.14
    n-butyric acid 871.55
    acetyl acetate 495.43
    di(2-ethylhexyl) phthalate 191.91
    ethyl propionate 629.25
    nitromethane 862.46
    1,2-diethoxyethane 1079.63
    benzonitrile 550.76
    trioctyl phosphate 192.9
    1-bromopropane 1595.06
    gamma-valerolactone 2300.0
    n-decanol 314.07
    triethyl phosphate 219.79
    4-methyl-2-pentanol 504.57
    propionitrile 1353.13
    vinylene carbonate 686.79
    1,1,2-trichlorotrifluoroethane 660.22
    DMS 457.27
    cumene 295.64
    2-octanol 434.0
    2-hexanone 948.57
    octyl acetate 386.14
    limonene 452.61
    1,2-dimethoxyethane 1987.76
    ethyl orthosilicate 253.45
    tributyl phosphate 212.72
    diacetone alcohol 673.52
    N,N-dimethylaniline 411.38
    acrylonitrile 1109.91
    aniline 603.02
    1,3-propanediol 560.79
    bromobenzene 833.42
    dibromomethane 1590.47
    1,1,2,2-tetrachloroethane 1837.1
    2-methyl-cyclohexyl acetate 449.13
    tetrabutyl urea 266.78
    diisobutyl methanol 378.0
    2-phenylethanol 579.95
    styrene 491.39
    dioctyl adipate 287.54
    dimethyl sulfate 392.12
    ethyl butyrate 614.99
    methyl lactate 243.37
    butyl lactate 330.57
    diethyl carbonate 335.51
    propanediol butyl ether 376.75
    triethyl orthoformate 423.37
    p-tert-butyltoluene 285.03
    methyl 4-tert-butylbenzoate 379.75
    morpholine 3235.92
    tert-butylamine 1243.04
    n-dodecanol 231.08
    dimethoxymethane 1685.7
    ethylene carbonate 718.45
    cyrene 315.87
    2-ethoxyethyl acetate 621.07
    2-ethylhexyl acetate 922.9
    1,2,4-trichlorobenzene 567.55
    4-methylpyridine 1468.01
    dibutyl ether 844.86
    2,6-dimethyl-4-heptanol 378.0
    DEF 1230.8
    dimethyl isosorbide 640.34
    tetrachloroethylene 1255.35
    eugenol 344.41
    triacetin 329.57
    span 80 357.16
    1,4-butanediol 203.89
    1,1-dichloroethane 1937.3
    2-methyl-1-pentanol 669.67
    methyl formate 601.88
    2-methyl-1-butanol 957.22
    n-decane 170.85
    butyronitrile 1475.91
    3,7-dimethyl-1-octanol 421.78
    1-chlorooctane 520.89
    1-chlorotetradecane 174.01
    n-nonane 192.68
    undecane 114.49
    tert-butylcyclohexane 258.41
    cyclooctane 324.51
    cyclopentanol 1084.02
    tetrahydropyran 4271.08
    tert-amyl methyl ether 1281.67
    2,5,8-trioxanonane 556.74
    1-hexene 1624.27
    2-isopropoxyethanol 545.59
    2,2,2-trifluoroethanol 142.94
    methyl butyrate 837.12

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction