4-Isopropylbenzyl alcohol

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    536-60-7

    Molecular formula
    C10H14O

    SMILES
    CC(C)C1=CC=C(C=C1)CO

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Herbal 73.92%
    Spicy 68.47%
    Woody 47.14%
    Green 44.78%
    Phenolic 40.9%
    Floral 37.44%
    Earthy 36.72%
    Leathery 34.56%
    Balsamic 34.55%
    Fresh 33.98%

     

    Flavor
    Herbal 66.04%
    Spicy 64.72%
    Woody 45.58%
    Spice 41.41%
    Herb 40.42%
    Fresh 35.28%
    Floral 33.43%
    Green 32.64%
    Medicinal 31.45%
    Cumin 31.43%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.3

    pKa est.
    8.38 (weak base)

    Molecular weight
    150.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Melting point expt.

    • 28 °C

    Boiling point

    • 135.00 to 136.00 °C. @ 26.00 mm Hg

    Flash point

    • 112.77 ˚C est.

    Solubility expt.

    • slightly
    • insoluble in water; soluble in organic solvents, oils
    • miscible at room temperature (in ethanol)

  • Synonyms

    • 4-isopropylbenzyl alcohol
    • 536-60-7
    • Cumic alcohol
    • Cuminol
    • (4-Isopropylphenyl)methanol
    • cuminyl alcohol
    • cuminic alcohol
    • Cumyl alcohol
    • p-Cymen-7-ol
    • CUMIN ALCOHOL
    • p-Isopropylbenzyl alcohol
    • p-cumic alcohol
    • Benzenemethanol, 4-(1-methylethyl)-
    • 4-(1-Methylethyl)benzenemethanol
    • Benzyl alcohol, p-isopropyl-
    • para-cymen-7-ol
    • (4-propan-2-ylphenyl)methanol
    • FEMA No. 2933
    • p-Cumin-7-ol
    • [4-(Propan-2-Yl)Phenyl]Methanol
    • NSC 15672
    • 4-(1-methylethyl)-benzenemethanol
    • EINECS 208-640-4
    • p-cymene-7-ol
    • BRN 0636665
    • DTXSID0021626
    • P-Mentha-1,3,5-trien-7-ol
    • AI3-20440
    • p-ISOPROPYL BENZYL ALCOHOL
    • V261W8XR62
    • 4-(1-methylethyl)benzene methanol
    • MFCD00004663
    • NSC-15672
    • CUMIC ALCOHOL [MI]
    • DTXCID301626
    • 4-ISOPROPYLBENZENEMETHANOL
    • CHEBI:27628
    • ISOPROPYLBENZYL ALCOHOL, P-
    • P-ISOPROPYLBENZYL ALCOHOL [FHFI]
    • Cuminylalcohol
    • (4-(propan-2-yl)phenyl)methanol
    • CAS-536-60-7
    • UNII-V261W8XR62
    • p-Cymen-7-ol, 8CI
    • 4-isopropyl-benzyl alcohol
    • p-Isopropyl-Benzyl alcohol
    • 4-Isopropyl benzyl alcohol
    • bmse000599
    • Cuminol ( p-cymen-7-ol)
    • SCHEMBL113930
    • (4-Isopropylphenyl)methanol #
    • WLN: Q1R DY1&1
    • CHEMBL3183500
    • 4-Isopropylbenzyl alcohol, 97%
    • FEMA 2933
    • OIGWAXDAPKFNCQ-UHFFFAOYSA-
    • HMS1789P06
    • AAA53660
    • HY-N7069
    • NSC15672
    • Tox21_202025
    • Tox21_302797
    • c0376
    • s5090
    • AKOS000121600
    • CCG-266208
    • CS-W018138
    • 4-(1-Methylethyl)benzenemethanol, 9CI
    • 4-Isopropylbenzyl alcohol, >=97%, FG
    • NCGC00249151-01
    • NCGC00256602-01
    • NCGC00259574-01
    • AS-59256
    • DA-62537
    • I0272
    • NS00012143
    • C06576
    • D97386
    • Q1143803
    • Z56347221
    • InChI=1/C10H14O/c1-8(2)10-5-3-9(7-11)4-6-10/h3-6,8,11H,7H2,1-2H3
    • 208-640-4

  • Applications

    4-Isopropylbenzyl alcohol (cuminalcohol, CAS 536-60-7) is used mainly as a synthetic intermediate: it can be esterified to give aromatic esters or carbonates used as additives and fragrance fixatives, etherified or converted to the corresponding benzyl halide (e.g., 4-isopropylbenzyl chloride) for preparing quaternary ammonium salts, surfactants and phase-transfer catalysts; it participates in selective oxidation/reduction sequences interconverting with cuminaldehyde and other benzyl derivatives to furnish building blocks for pharmaceuticals, dyes and agrochemicals; it also serves as a fragrance modifier in perfumes, soaps and household care due to its warm, slightly spicy, cumin-like note, helping adjust accords and improve substantivity; in research, it is a convenient model substrate for benzyl alcohol oxidation, transfer-hydrogenation and homogeneous/heterogeneous catalysis studies, and a hydrophobic benzyl unit for tethering onto polymers or surface-functional materials.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2917.88
    methanol 2309.29
    isopropanol 1913.38
    water 0.79
    ethyl acetate 3645.23
    n-propanol 2865.25
    acetone 3391.28
    n-butanol 2178.41
    acetonitrile 3637.5
    DMF 2357.11
    toluene 664.76
    isobutanol 1448.23
    1,4-dioxane 3360.0
    methyl acetate 2761.3
    THF 3549.87
    2-butanone 3051.26
    n-pentanol 1095.22
    sec-butanol 1492.87
    n-hexane 150.97
    ethylene glycol 245.25
    NMP 1616.26
    cyclohexane 198.0
    DMSO 2916.27
    n-butyl acetate 2107.56
    n-octanol 257.13
    chloroform 2838.95
    n-propyl acetate 1547.05
    acetic acid 1436.98
    dichloromethane 3384.57
    cyclohexanone 2368.29
    propylene glycol 425.75
    isopropyl acetate 1283.59
    DMAc 1098.11
    2-ethoxyethanol 1515.34
    isopentanol 1419.45
    n-heptane 81.56
    ethyl formate 1741.3
    1,2-dichloroethane 2878.76
    n-hexanol 1244.22
    2-methoxyethanol 2846.4
    isobutyl acetate 594.87
    tetrachloromethane 565.04
    n-pentyl acetate 531.34
    transcutol 4031.48
    n-heptanol 338.0
    ethylbenzene 282.05
    MIBK 814.2
    2-propoxyethanol 1883.08
    tert-butanol 1938.36
    MTBE 2019.07
    2-butoxyethanol 704.79
    propionic acid 1699.33
    o-xylene 311.53
    formic acid 462.07
    diethyl ether 3421.03
    m-xylene 379.65
    p-xylene 302.14
    chlorobenzene 955.79
    dimethyl carbonate 556.33
    n-octane 20.63
    formamide 1444.72
    cyclopentanone 3079.07
    2-pentanone 2398.62
    anisole 825.58
    cyclopentyl methyl ether 1754.89
    gamma-butyrolactone 3484.57
    1-methoxy-2-propanol 1642.34
    pyridine 2466.99
    3-pentanone 1781.7
    furfural 1979.68
    n-dodecane 9.74
    diethylene glycol 815.57
    diisopropyl ether 505.02
    tert-amyl alcohol 1441.14
    acetylacetone 1455.95
    n-hexadecane 11.99
    acetophenone 562.49
    methyl propionate 2298.3
    isopentyl acetate 1201.27
    trichloroethylene 4032.04
    n-nonanol 211.3
    cyclohexanol 1077.47
    benzyl alcohol 576.73
    2-ethylhexanol 567.91
    isooctanol 262.09
    dipropyl ether 1118.64
    1,2-dichlorobenzene 724.36
    ethyl lactate 355.82
    propylene carbonate 1386.62
    n-methylformamide 2816.68
    2-pentanol 1246.57
    n-pentane 158.84
    1-propoxy-2-propanol 1311.86
    1-methoxy-2-propyl acetate 1296.82
    2-(2-methoxypropoxy) propanol 416.8
    mesitylene 219.06
    ε-caprolactone 2043.43
    p-cymene 163.18
    epichlorohydrin 3644.74
    1,1,1-trichloroethane 1966.37
    2-aminoethanol 915.08
    morpholine-4-carbaldehyde 1917.21
    sulfolane 2564.41
    2,2,4-trimethylpentane 65.8
    2-methyltetrahydrofuran 3135.38
    n-hexyl acetate 605.93
    isooctane 56.6
    2-(2-butoxyethoxy)ethanol 755.43
    sec-butyl acetate 747.3
    tert-butyl acetate 1053.83
    decalin 69.96
    glycerin 424.45
    diglyme 1737.56
    acrylic acid 1080.38
    isopropyl myristate 156.93
    n-butyric acid 2412.45
    acetyl acetate 870.33
    di(2-ethylhexyl) phthalate 139.42
    ethyl propionate 1173.54
    nitromethane 3667.76
    1,2-diethoxyethane 1772.27
    benzonitrile 835.85
    trioctyl phosphate 112.74
    1-bromopropane 1404.03
    gamma-valerolactone 3173.84
    n-decanol 137.71
    triethyl phosphate 250.21
    4-methyl-2-pentanol 455.52
    propionitrile 2540.52
    vinylene carbonate 1192.26
    1,1,2-trichlorotrifluoroethane 1620.2
    DMS 467.12
    cumene 163.87
    2-octanol 184.38
    2-hexanone 1320.13
    octyl acetate 206.43
    limonene 295.78
    1,2-dimethoxyethane 2389.3
    ethyl orthosilicate 272.49
    tributyl phosphate 171.6
    diacetone alcohol 1021.2
    N,N-dimethylaniline 366.71
    acrylonitrile 2543.57
    aniline 1219.57
    1,3-propanediol 1338.75
    bromobenzene 873.64
    dibromomethane 2156.64
    1,1,2,2-tetrachloroethane 2728.46
    2-methyl-cyclohexyl acetate 444.82
    tetrabutyl urea 188.05
    diisobutyl methanol 274.66
    2-phenylethanol 630.68
    styrene 418.81
    dioctyl adipate 230.92
    dimethyl sulfate 681.11
    ethyl butyrate 1190.09
    methyl lactate 500.15
    butyl lactate 370.95
    diethyl carbonate 570.24
    propanediol butyl ether 459.11
    triethyl orthoformate 593.75
    p-tert-butyltoluene 157.18
    methyl 4-tert-butylbenzoate 323.55
    morpholine 4516.46
    tert-butylamine 1306.31
    n-dodecanol 92.16
    dimethoxymethane 1934.6
    ethylene carbonate 1106.61
    cyrene 385.97
    2-ethoxyethyl acetate 826.15
    2-ethylhexyl acetate 894.36
    1,2,4-trichlorobenzene 826.21
    4-methylpyridine 2001.7
    dibutyl ether 499.66
    2,6-dimethyl-4-heptanol 274.66
    DEF 2162.72
    dimethyl isosorbide 779.65
    tetrachloroethylene 1831.87
    eugenol 326.89
    triacetin 414.49
    span 80 339.85
    1,4-butanediol 366.54
    1,1-dichloroethane 2419.26
    2-methyl-1-pentanol 782.25
    methyl formate 1524.07
    2-methyl-1-butanol 1386.8
    n-decane 22.42
    butyronitrile 2224.84
    3,7-dimethyl-1-octanol 281.49
    1-chlorooctane 162.08
    1-chlorotetradecane 42.03
    n-nonane 24.05
    undecane 13.86
    tert-butylcyclohexane 72.93
    cyclooctane 58.5
    cyclopentanol 1179.15
    tetrahydropyran 3643.24
    tert-amyl methyl ether 1123.24
    2,5,8-trioxanonane 771.56
    1-hexene 651.67
    2-isopropoxyethanol 838.07
    2,2,2-trifluoroethanol 363.33
    methyl butyrate 1545.88

    Scent© AI

1 4

IFRA standard 51

Recommendation
Restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 0.45 % Category 7A
Rinse-off products applied to the hair with some hand contact
 0.8 %
Category 2
Products applied to the axillae
 0.14 % Category 7B
Leave-on products applied to the hair with some hand contact
 0.8 %
Category 3
Products applied to the face/body using fingertips
 0.4 % Category 8
Products with significant anogenital exposure
 0.21 %
Category 4
Products related to fine fragrance
 2.5 % Category 9
Products with body and hand exposure, primarily rinse off
 2 %
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 0.64 % Category 10A
Household care products with mostly hand contact
 2 %
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 0.64 % Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 4.8 %
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 0.64 % Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 0.21 %
Category 5D
Baby Creams, baby Oils and baby talc
 0.21 % Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 0.21 %
Category 6
Products with oral and lip exposure
 1.5 % Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Laurel leaf (Turkey) 4 8006-78-8 Laurus nobilis L., fam. Lauraceae 0.05%