4-Hydroxydecanoic acid

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  • Identifiers

    CAS number
    17369-51-6

    Molecular formula
    C10H20O3

    SMILES
    CCCCCCC(CCC(=O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Fatty 57.13%
    Oily 49.77%
    Fruity 49.08%
    Cheesy 46.0%
    Dairy 42.86%
    Lactonic 42.41%
    Milky 39.92%
    Buttery 38.72%
    Creamy 37.59%
    Waxy 36.93%

     

    Flavor
    Fatty 45.5%
    Cheese 38.63%
    Oily 37.53%
    Odorless 35.92%
    Waxy 33.3%
    Sour 30.37%
    Green 29.95%
    Mild 29.11%
    Sweat 28.2%
    Cheesy 26.46%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.3

    pKa est.
    7.24 (neutral)

    Molecular weight
    188.26 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    315°C

    Flash point

    • 159.97 ˚C est.

  • Synonyms

    • 4-HYDROXYDECANOIC ACID
    • 17369-51-6
    • DTXSID10938421
    • RefChem:912581
    • DTXCID901366955
    • 4-hydroxycapric acid
    • Decanoic acid, 4-hydroxy-
    • 4-hydroxy capric acid
    • 4-HYDROXYDECANOICACID
    • SCHEMBL317386
    • SCHEMBL3343272
    • CHEBI:165409
    • LMFA01050031
    • AKOS010914269
    • CS-0297491
    • EN300-81498
    • G81050
    • 17369-51-6

  • Applications

    4-Hydroxydecanoic acid (CAS 17369-51-6) is a versatile building block in organic synthesis, commonly used to prepare esters and derivatives that serve in cosmetics and perfumery as emollients and fragrance components. It also serves as a feedstock for biodegradable polyesters and specialty polymers used in coatings, adhesives, and packaging. Through esterification with fatty alcohols, it yields surfactant and emulsifier derivatives employed in household cleaners and personal care formulations. Its hydroxy fatty acid functionality also enables use as a precursor for lubricants and plasticizers in polymer systems.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1518.6
    methanol 2611.9
    isopropanol 904.55
    water 1.85
    ethyl acetate 345.75
    n-propanol 809.78
    acetone 732.13
    n-butanol 608.88
    acetonitrile 162.88
    DMF 1212.64
    toluene 35.85
    isobutanol 526.37
    1,4-dioxane 450.28
    methyl acetate 200.32
    THF 1097.48
    2-butanone 315.41
    n-pentanol 474.32
    sec-butanol 482.53
    n-hexane 32.57
    ethylene glycol 395.02
    NMP 514.12
    cyclohexane 17.0
    DMSO 1909.95
    n-butyl acetate 325.83
    n-octanol 130.53
    chloroform 92.91
    n-propyl acetate 272.25
    acetic acid 629.77
    dichloromethane 87.27
    cyclohexanone 449.8
    propylene glycol 529.76
    isopropyl acetate 295.99
    DMAc 683.8
    2-ethoxyethanol 839.78
    isopentanol 615.67
    n-heptane 10.92
    ethyl formate 212.77
    1,2-dichloroethane 133.27
    n-hexanol 426.84
    2-methoxyethanol 1440.07
    isobutyl acetate 197.57
    tetrachloromethane 29.83
    n-pentyl acetate 144.69
    transcutol 1361.99
    n-heptanol 153.35
    ethylbenzene 42.86
    MIBK 312.73
    2-propoxyethanol 750.21
    tert-butanol 1232.69
    MTBE 447.91
    2-butoxyethanol 354.97
    propionic acid 391.69
    o-xylene 46.64
    formic acid 392.34
    diethyl ether 202.77
    m-xylene 55.01
    p-xylene 55.26
    chlorobenzene 51.21
    dimethyl carbonate 78.89
    n-octane 5.64
    formamide 497.95
    cyclopentanone 596.65
    2-pentanone 413.49
    anisole 128.79
    cyclopentyl methyl ether 366.0
    gamma-butyrolactone 574.56
    1-methoxy-2-propanol 1059.26
    pyridine 170.8
    3-pentanone 154.23
    furfural 403.29
    n-dodecane 4.47
    diethylene glycol 623.06
    diisopropyl ether 86.82
    tert-amyl alcohol 703.52
    acetylacetone 436.32
    n-hexadecane 4.98
    acetophenone 143.11
    methyl propionate 211.45
    isopentyl acetate 314.29
    trichloroethylene 193.95
    n-nonanol 112.42
    cyclohexanol 317.44
    benzyl alcohol 172.07
    2-ethylhexanol 189.81
    isooctanol 131.16
    dipropyl ether 133.71
    1,2-dichlorobenzene 60.37
    ethyl lactate 145.68
    propylene carbonate 295.1
    n-methylformamide 626.5
    2-pentanol 346.85
    n-pentane 14.38
    1-propoxy-2-propanol 484.34
    1-methoxy-2-propyl acetate 327.0
    2-(2-methoxypropoxy) propanol 263.48
    mesitylene 43.97
    ε-caprolactone 385.3
    p-cymene 34.46
    epichlorohydrin 480.19
    1,1,1-trichloroethane 93.72
    2-aminoethanol 903.29
    morpholine-4-carbaldehyde 590.46
    sulfolane 757.11
    2,2,4-trimethylpentane 13.48
    2-methyltetrahydrofuran 568.68
    n-hexyl acetate 198.34
    isooctane 13.45
    2-(2-butoxyethoxy)ethanol 446.29
    sec-butyl acetate 191.22
    tert-butyl acetate 363.57
    decalin 16.45
    glycerin 557.86
    diglyme 664.71
    acrylic acid 267.86
    isopropyl myristate 67.62
    n-butyric acid 649.76
    acetyl acetate 155.37
    di(2-ethylhexyl) phthalate 82.07
    ethyl propionate 184.61
    nitromethane 621.3
    1,2-diethoxyethane 277.77
    benzonitrile 122.14
    trioctyl phosphate 66.71
    1-bromopropane 67.36
    gamma-valerolactone 721.45
    n-decanol 80.07
    triethyl phosphate 77.54
    4-methyl-2-pentanol 241.18
    propionitrile 170.7
    vinylene carbonate 199.31
    1,1,2-trichlorotrifluoroethane 433.46
    DMS 114.98
    cumene 42.15
    2-octanol 92.03
    2-hexanone 296.26
    octyl acetate 87.44
    limonene 55.48
    1,2-dimethoxyethane 912.86
    ethyl orthosilicate 79.32
    tributyl phosphate 81.73
    diacetone alcohol 553.28
    N,N-dimethylaniline 107.59
    acrylonitrile 190.9
    aniline 118.63
    1,3-propanediol 980.97
    bromobenzene 40.77
    dibromomethane 63.13
    1,1,2,2-tetrachloroethane 206.47
    2-methyl-cyclohexyl acetate 147.83
    tetrabutyl urea 106.54
    diisobutyl methanol 102.1
    2-phenylethanol 174.75
    styrene 44.8
    dioctyl adipate 114.3
    dimethyl sulfate 162.86
    ethyl butyrate 183.7
    methyl lactate 205.84
    butyl lactate 169.78
    diethyl carbonate 100.42
    propanediol butyl ether 369.09
    triethyl orthoformate 123.83
    p-tert-butyltoluene 36.59
    methyl 4-tert-butylbenzoate 149.13
    morpholine 757.6
    tert-butylamine 535.59
    n-dodecanol 55.23
    dimethoxymethane 497.35
    ethylene carbonate 190.96
    cyrene 222.41
    2-ethoxyethyl acetate 206.78
    2-ethylhexyl acetate 199.1
    1,2,4-trichlorobenzene 74.55
    4-methylpyridine 198.78
    dibutyl ether 102.05
    2,6-dimethyl-4-heptanol 102.1
    DEF 419.38
    dimethyl isosorbide 375.19
    tetrachloroethylene 155.58
    eugenol 172.88
    triacetin 173.86
    span 80 238.84
    1,4-butanediol 416.77
    1,1-dichloroethane 93.81
    2-methyl-1-pentanol 390.8
    methyl formate 284.25
    2-methyl-1-butanol 442.11
    n-decane 8.11
    butyronitrile 243.58
    3,7-dimethyl-1-octanol 145.23
    1-chlorooctane 39.02
    1-chlorotetradecane 14.57
    n-nonane 7.6
    undecane 5.75
    tert-butylcyclohexane 20.19
    cyclooctane 6.72
    cyclopentanol 482.1
    tetrahydropyran 392.05
    tert-amyl methyl ether 268.34
    2,5,8-trioxanonane 440.4
    1-hexene 121.25
    2-isopropoxyethanol 539.0
    2,2,2-trifluoroethanol 153.91
    methyl butyrate 311.52

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction