4-Hydroxy-2-dodecenal

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  • Identifiers

    CAS number
    29343-60-0

    Molecular formula
    C12H22O2

    SMILES
    CCCCCCCCC(/C=C/C=O)O

    Safety labels

  • Odor profile

    Fragrance
    Fatty 60.89%
    Green 51.07%
    Mushroom 48.84%
    Waxy 48.59%
    Citrus 47.93%
    Oily 45.05%
    Metallic 43.73%
    Aldehydic 42.74%
    Earthy 41.58%
    Fresh 41.03%

     

    Flavor
    Green 69.47%
    Waxy 56.22%
    Fatty 45.86%
    Oily 44.98%
    Fresh 44.43%
    Herbal 43.29%
    Fruity 38.25%
    Citrus 37.65%
    Mushroom 37.51%
    Floral 37.38%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    3.3

    pKa est.
    7.68 (neutral)

    Molecular weight
    198.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    304°C

    Flash point

    • 141.26 ˚C est.

  • Synonyms

    • 4-Hydroxy-2-dodecenal
    • 29343-60-0
    • (E)-4-hydroxy-dodec-2-enal
    • SCHEMBL8309537
    • 29343-60-0

  • Applications

    4-Hydroxy-2-dodecenal, CAS 29343-60-0, is commonly used as a fragrance ingredient in perfumes and personal care products, providing characteristic odor notes, and it also serves as an intermediate in fragrance synthesis for the development of related odorants. It may be evaluated for potential use as a flavor/aroma compound in food processing at the research or formulation stage, and can be incorporated into household products and cleaners as a scent additive. In industrial manufacturing, it can function as a building block for specialty chemicals in fragrance platforms and as a reactive intermediate for further chemical transformations. Actual usage depends on local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1211.8
    methanol 1152.66
    isopropanol 1101.64
    water 0.02
    ethyl acetate 1099.44
    n-propanol 999.33
    acetone 1504.07
    n-butanol 897.64
    acetonitrile 532.33
    DMF 886.17
    toluene 268.38
    isobutanol 678.27
    1,4-dioxane 926.89
    methyl acetate 601.58
    THF 2215.19
    2-butanone 1138.6
    n-pentanol 621.46
    sec-butanol 789.57
    n-hexane 204.05
    ethylene glycol 57.68
    NMP 599.85
    cyclohexane 214.38
    DMSO 1869.47
    n-butyl acetate 1013.65
    n-octanol 183.01
    chloroform 962.62
    n-propyl acetate 834.33
    acetic acid 369.76
    dichloromethane 1092.88
    cyclohexanone 1296.91
    propylene glycol 161.41
    isopropyl acetate 718.46
    DMAc 550.27
    2-ethoxyethanol 667.44
    isopentanol 801.15
    n-heptane 91.86
    ethyl formate 378.14
    1,2-dichloroethane 1079.42
    n-hexanol 724.12
    2-methoxyethanol 1031.82
    isobutyl acetate 483.35
    tetrachloromethane 178.28
    n-pentyl acetate 428.86
    transcutol 2168.94
    n-heptanol 221.36
    ethylbenzene 167.13
    MIBK 658.62
    2-propoxyethanol 880.77
    tert-butanol 1244.07
    MTBE 1122.91
    2-butoxyethanol 420.28
    propionic acid 387.77
    o-xylene 166.55
    formic acid 67.2
    diethyl ether 1354.36
    m-xylene 208.61
    p-xylene 192.96
    chlorobenzene 331.28
    dimethyl carbonate 124.14
    n-octane 28.9
    formamide 120.9
    cyclopentanone 1296.06
    2-pentanone 1219.23
    anisole 321.65
    cyclopentyl methyl ether 1043.58
    gamma-butyrolactone 1075.12
    1-methoxy-2-propanol 963.6
    pyridine 762.49
    3-pentanone 592.14
    furfural 648.42
    n-dodecane 16.21
    diethylene glycol 403.78
    diisopropyl ether 318.69
    tert-amyl alcohol 798.94
    acetylacetone 803.02
    n-hexadecane 18.99
    acetophenone 311.03
    methyl propionate 593.96
    isopentyl acetate 812.29
    trichloroethylene 1365.63
    n-nonanol 165.82
    cyclohexanol 689.06
    benzyl alcohol 273.73
    2-ethylhexanol 423.51
    isooctanol 199.71
    dipropyl ether 720.62
    1,2-dichlorobenzene 309.2
    ethyl lactate 223.39
    propylene carbonate 536.87
    n-methylformamide 370.35
    2-pentanol 694.52
    n-pentane 119.89
    1-propoxy-2-propanol 799.63
    1-methoxy-2-propyl acetate 671.02
    2-(2-methoxypropoxy) propanol 333.66
    mesitylene 143.74
    ε-caprolactone 872.12
    p-cymene 120.43
    epichlorohydrin 1394.39
    1,1,1-trichloroethane 798.25
    2-aminoethanol 236.18
    morpholine-4-carbaldehyde 641.42
    sulfolane 1228.29
    2,2,4-trimethylpentane 51.47
    2-methyltetrahydrofuran 1579.7
    n-hexyl acetate 457.87
    isooctane 48.13
    2-(2-butoxyethoxy)ethanol 507.23
    sec-butyl acetate 534.33
    tert-butyl acetate 718.48
    decalin 79.4
    glycerin 175.65
    diglyme 936.79
    acrylic acid 210.61
    isopropyl myristate 165.58
    n-butyric acid 908.24
    acetyl acetate 376.18
    di(2-ethylhexyl) phthalate 122.44
    ethyl propionate 593.33
    nitromethane 623.02
    1,2-diethoxyethane 970.31
    benzonitrile 349.42
    trioctyl phosphate 104.09
    1-bromopropane 885.05
    gamma-valerolactone 1228.57
    n-decanol 117.92
    triethyl phosphate 185.46
    4-methyl-2-pentanol 351.35
    propionitrile 583.64
    vinylene carbonate 379.69
    1,1,2-trichlorotrifluoroethane 678.1
    DMS 249.66
    cumene 118.11
    2-octanol 153.66
    2-hexanone 835.41
    octyl acetate 188.34
    limonene 231.57
    1,2-dimethoxyethane 1185.14
    ethyl orthosilicate 198.14
    tributyl phosphate 147.39
    diacetone alcohol 679.59
    N,N-dimethylaniline 199.5
    acrylonitrile 508.19
    aniline 320.72
    1,3-propanediol 440.61
    bromobenzene 361.15
    dibromomethane 864.79
    1,1,2,2-tetrachloroethane 1143.25
    2-methyl-cyclohexyl acetate 358.75
    tetrabutyl urea 179.15
    diisobutyl methanol 240.01
    2-phenylethanol 308.8
    styrene 219.4
    dioctyl adipate 228.15
    dimethyl sulfate 213.96
    ethyl butyrate 606.26
    methyl lactate 202.73
    butyl lactate 299.75
    diethyl carbonate 297.35
    propanediol butyl ether 313.94
    triethyl orthoformate 356.56
    p-tert-butyltoluene 120.8
    methyl 4-tert-butylbenzoate 241.22
    morpholine 1485.03
    tert-butylamine 781.23
    n-dodecanol 86.33
    dimethoxymethane 734.94
    ethylene carbonate 370.68
    cyrene 261.28
    2-ethoxyethyl acetate 509.19
    2-ethylhexyl acetate 577.55
    1,2,4-trichlorobenzene 344.04
    4-methylpyridine 723.05
    dibutyl ether 457.6
    2,6-dimethyl-4-heptanol 240.01
    DEF 874.72
    dimethyl isosorbide 557.01
    tetrachloroethylene 738.76
    eugenol 233.95
    triacetin 337.7
    span 80 295.01
    1,4-butanediol 158.49
    1,1-dichloroethane 1016.67
    2-methyl-1-pentanol 490.73
    methyl formate 207.05
    2-methyl-1-butanol 645.82
    n-decane 33.58
    butyronitrile 823.9
    3,7-dimethyl-1-octanol 241.89
    1-chlorooctane 162.08
    1-chlorotetradecane 51.2
    n-nonane 35.89
    undecane 22.07
    tert-butylcyclohexane 75.76
    cyclooctane 57.09
    cyclopentanol 654.09
    tetrahydropyran 1774.22
    tert-amyl methyl ether 659.52
    2,5,8-trioxanonane 565.6
    1-hexene 707.88
    2-isopropoxyethanol 530.66
    2,2,2-trifluoroethanol 77.94
    methyl butyrate 835.1

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction