(4-(Hexyloxy)-2-hydroxyphenyl)(phenyl)methanone

Overview IFRA Request a quote

  • Identifiers

    CAS number
    3293-97-8

    Molecular formula
    C19H22O3

    SMILES
    CCCCCCOC1=CC(=C(C=C1)C(=O)C2=CC=CC=C2)O

    Safety labels

  • Odor profile

    Fragrance
    Sweet 72.88%
    Balsamic 65.62%
    Floral 64.87%
    Spicy 45.51%
    Herbal 44.59%
    Fruity 39.93%
    Vanilla 30.4%
    Aromatic 29.04%
    Warm 26.31%
    Powdery 24.87%

     

    Flavor
    Bitter 49.81%
    Herbal 43.07%
    Balsam 30.73%
    Woody 26.29%
    Spicy 23.69%
    Lovage 21.98%
    Valerian 20.77%
    Ethyl benzoate 20.72%
    Parsley 20.19%
    Floral 20.02%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.8

    pKa est.
    8.78 (weak base)

    Molecular weight
    298.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    428°C

    Flash point

    • 182.01 ˚C est.

  • Synonyms

    • 3293-97-8
    • (4-(HEXYLOXY)-2-HYDROXYPHENYL)(PHENYL)METHANONE
    • (4-hexoxy-2-hydroxyphenyl)-phenylmethanone
    • WH87PV776W
    • 2-Hydroxy-4-n-hexyloxybenzophenone
    • UNII-WH87PV776W
    • [4-(hexyloxy)-2-hydroxyphenyl]phenylmethanone
    • (4-(Hexyloxy)-2-hydroxyphenyl)phenylmethanone
    • Methanone, (4-(hexyloxy)-2-hydroxyphenyl)phenyl-
    • Methanone, [4-(hexyloxy)-2-hydroxyphenyl]phenyl-
    • SCHEMBL4605203
    • SCHEMBL29543820
    • DTXSID001337834
    • MSK163443
    • AKOS024344673
    • 4-hexyloxy-2-hydroxyphenyl phenyl ketone
    • MSK163443-1000M
    • ST50564862
    • [4-(Hexyloxy)-2-hydroxyphenyl]phenylmethanone Solution in Methanol, 1000ug/mL
    • 3293-97-8

  • Applications

    (4-(Hexyloxy)-2-hydroxyphenyl)(phenyl)methanone, CAS 3293-97-8, is a benzophenone derivative bearing a hexyloxy substituent and a phenolic OH. In industrial practice it is viewed as an intermediate for the synthesis of benzophenone derivatives and as a potential UV absorber for polymers, coatings, and personal care formulations that favor oil solubility due to the lipophilic hexyloxy group. It may serve as a photostabilizer in polymers, coatings, and cosmetics, and could participate as a photosensitizer or photoinitiator precursor in UV-curing systems; additionally, it is commonly evaluated as a benzophenone-type UV absorber candidate, subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 814.92
    methanol 920.08
    isopropanol 433.77
    water 0.07
    ethyl acetate 1387.53
    n-propanol 762.15
    acetone 2707.84
    n-butanol 494.09
    acetonitrile 1137.81
    DMF 2437.15
    toluene 550.19
    isobutanol 412.3
    1,4-dioxane 878.32
    methyl acetate 1197.08
    THF 1957.01
    2-butanone 1459.18
    n-pentanol 217.07
    sec-butanol 377.01
    n-hexane 5.48
    ethylene glycol 85.73
    NMP 1587.95
    cyclohexane 28.03
    DMSO 3936.12
    n-butyl acetate 449.72
    n-octanol 58.05
    chloroform 2366.88
    n-propyl acetate 470.71
    acetic acid 730.55
    dichloromethane 3109.23
    cyclohexanone 1754.15
    propylene glycol 218.37
    isopropyl acetate 607.52
    DMAc 1729.32
    2-ethoxyethanol 425.06
    isopentanol 330.89
    n-heptane 3.68
    ethyl formate 469.2
    1,2-dichloroethane 2998.86
    n-hexanol 160.65
    2-methoxyethanol 1135.04
    isobutyl acetate 256.65
    tetrachloromethane 134.94
    n-pentyl acetate 226.23
    transcutol 1874.02
    n-heptanol 71.03
    ethylbenzene 126.7
    MIBK 446.03
    2-propoxyethanol 439.18
    tert-butanol 448.92
    MTBE 447.45
    2-butoxyethanol 218.63
    propionic acid 607.1
    o-xylene 182.72
    formic acid 157.83
    diethyl ether 699.83
    m-xylene 194.34
    p-xylene 156.57
    chlorobenzene 873.65
    dimethyl carbonate 549.01
    n-octane 2.45
    formamide 550.3
    cyclopentanone 2416.71
    2-pentanone 1109.01
    anisole 380.42
    cyclopentyl methyl ether 776.14
    gamma-butyrolactone 2179.09
    1-methoxy-2-propanol 754.77
    pyridine 1606.29
    3-pentanone 784.29
    furfural 1243.23
    n-dodecane 4.05
    diethylene glycol 342.26
    diisopropyl ether 105.19
    tert-amyl alcohol 319.42
    acetylacetone 1380.57
    n-hexadecane 4.98
    acetophenone 396.41
    methyl propionate 1175.33
    isopentyl acetate 367.8
    trichloroethylene 4048.13
    n-nonanol 60.34
    cyclohexanol 500.18
    benzyl alcohol 325.94
    2-ethylhexanol 91.04
    isooctanol 66.22
    dipropyl ether 140.78
    1,2-dichlorobenzene 573.03
    ethyl lactate 192.36
    propylene carbonate 898.03
    n-methylformamide 1023.77
    2-pentanol 245.75
    n-pentane 5.25
    1-propoxy-2-propanol 286.13
    1-methoxy-2-propyl acetate 475.64
    2-(2-methoxypropoxy) propanol 235.92
    mesitylene 89.68
    ε-caprolactone 1099.8
    p-cymene 58.51
    epichlorohydrin 3017.17
    1,1,1-trichloroethane 1394.12
    2-aminoethanol 285.68
    morpholine-4-carbaldehyde 1060.73
    sulfolane 2537.86
    2,2,4-trimethylpentane 9.4
    2-methyltetrahydrofuran 1088.51
    n-hexyl acetate 274.67
    isooctane 6.96
    2-(2-butoxyethoxy)ethanol 361.24
    sec-butyl acetate 289.02
    tert-butyl acetate 534.54
    decalin 15.73
    glycerin 252.81
    diglyme 825.14
    acrylic acid 492.34
    isopropyl myristate 95.86
    n-butyric acid 866.89
    acetyl acetate 653.84
    di(2-ethylhexyl) phthalate 96.93
    ethyl propionate 406.33
    nitromethane 2214.63
    1,2-diethoxyethane 488.46
    benzonitrile 488.4
    trioctyl phosphate 66.84
    1-bromopropane 802.85
    gamma-valerolactone 2010.35
    n-decanol 44.46
    triethyl phosphate 127.18
    4-methyl-2-pentanol 110.96
    propionitrile 705.11
    vinylene carbonate 731.21
    1,1,2-trichlorotrifluoroethane 1247.22
    DMS 392.0
    cumene 65.46
    2-octanol 48.01
    2-hexanone 430.5
    octyl acetate 123.28
    limonene 92.65
    1,2-dimethoxyethane 725.73
    ethyl orthosilicate 110.82
    tributyl phosphate 98.15
    diacetone alcohol 536.06
    N,N-dimethylaniline 165.26
    acrylonitrile 1047.93
    aniline 708.89
    1,3-propanediol 437.52
    bromobenzene 899.93
    dibromomethane 1750.54
    1,1,2,2-tetrachloroethane 2820.65
    2-methyl-cyclohexyl acetate 192.04
    tetrabutyl urea 128.9
    diisobutyl methanol 61.52
    2-phenylethanol 241.63
    styrene 231.7
    dioctyl adipate 168.59
    dimethyl sulfate 817.69
    ethyl butyrate 279.93
    methyl lactate 423.63
    butyl lactate 192.45
    diethyl carbonate 197.73
    propanediol butyl ether 201.72
    triethyl orthoformate 167.45
    p-tert-butyltoluene 55.33
    methyl 4-tert-butylbenzoate 236.23
    morpholine 1333.5
    tert-butylamine 193.3
    n-dodecanol 34.41
    dimethoxymethane 1349.21
    ethylene carbonate 640.69
    cyrene 246.9
    2-ethoxyethyl acetate 405.42
    2-ethylhexyl acetate 259.03
    1,2,4-trichlorobenzene 724.73
    4-methylpyridine 1373.02
    dibutyl ether 129.56
    2,6-dimethyl-4-heptanol 61.52
    DEF 1079.32
    dimethyl isosorbide 459.22
    tetrachloroethylene 1326.24
    eugenol 214.48
    triacetin 326.91
    span 80 184.83
    1,4-butanediol 114.98
    1,1-dichloroethane 2085.55
    2-methyl-1-pentanol 202.88
    methyl formate 681.46
    2-methyl-1-butanol 357.01
    n-decane 6.09
    butyronitrile 569.71
    3,7-dimethyl-1-octanol 81.04
    1-chlorooctane 56.14
    1-chlorotetradecane 22.14
    n-nonane 4.77
    undecane 4.81
    tert-butylcyclohexane 12.55
    cyclooctane 5.56
    cyclopentanol 549.95
    tetrahydropyran 1188.22
    tert-amyl methyl ether 276.52
    2,5,8-trioxanonane 464.58
    1-hexene 63.11
    2-isopropoxyethanol 268.19
    2,2,2-trifluoroethanol 226.68
    methyl butyrate 572.25

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction