(4)-Gingerol

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  • Identifiers

    CAS number
    41743-68-4

    Molecular formula
    C15H22O4

    SMILES
    CCC[C@@H](CC(=O)CCC1=CC(=C(C=C1)O)OC)O

    Safety labels

  • Odor profile

    Fragrance
    Sweet 53.66%
    Vanilla 47.7%
    Spicy 37.58%
    Creamy 34.14%
    Milky 28.6%
    Balsamic 27.71%
    Savory 26.93%
    Fruity 26.24%
    Odorless 25.95%
    Caramellic 23.85%

     

    Flavor
    Sweet 35.05%
    Odorless 32.11%
    Woody 30.06%
    Mild 29.99%
    Spicy 28.95%
    Fruity 24.76%
    Herbal 24.62%
    Bland 21.67%
    Ham 20.47%
    Animal 20.14%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    10.34 (weak base)

    Molecular weight
    266.33 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    431°C

    Flash point

    • 173.07 ˚C est.

  • Synonyms

    • [4]-Gingerol
    • (4)-Gingerol
    • 41743-68-4
    • (5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)octan-3-one
    • RefChem:69428
    • GDRKZARFCIYVCI-UHFFFAOYSA-N
    • orb1680970
    • SCHEMBL31091264
    • (5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-octanone
    • DTXSID001044358
    • AKOS040762918
    • H63821
    • 41743-68-4

  • Applications

    (4)-Gingerol, CAS 41743-68-4, is primarily used as a fragrance ingredient in perfumery and as a flavor/aroma component in food processing. In cosmetics and personal care, it often serves as a natural fragrance contributor in formulations such as creams and lotions. In household products and cleaning applications, it can be incorporated to impart a ginger-like aroma in cleaners and air fresheners. In industrial manufacturing, it is commonly treated as an intermediate or starting material for the synthesis of gingerol derivatives used in fragrance and cosmetic applications.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1210.29
    methanol 2599.68
    isopropanol 546.35
    water 0.67
    ethyl acetate 297.73
    n-propanol 508.48
    acetone 877.12
    n-butanol 284.31
    acetonitrile 350.33
    DMF 536.15
    toluene 21.51
    isobutanol 202.75
    1,4-dioxane 706.5
    methyl acetate 255.88
    THF 995.8
    2-butanone 249.23
    n-pentanol 159.23
    sec-butanol 205.37
    n-hexane 0.52
    ethylene glycol 238.44
    NMP 158.43
    cyclohexane 2.22
    DMSO 2306.28
    n-butyl acetate 76.58
    n-octanol 41.22
    chloroform 164.28
    n-propyl acetate 99.86
    acetic acid 703.69
    dichloromethane 192.74
    cyclohexanone 256.1
    propylene glycol 380.55
    isopropyl acetate 120.55
    DMAc 383.86
    2-ethoxyethanol 521.79
    isopentanol 167.37
    n-heptane 0.72
    ethyl formate 168.98
    1,2-dichloroethane 170.66
    n-hexanol 94.96
    2-methoxyethanol 1320.53
    isobutyl acetate 64.07
    tetrachloromethane 11.22
    n-pentyl acetate 44.12
    transcutol 776.05
    n-heptanol 41.09
    ethylbenzene 14.02
    MIBK 103.68
    2-propoxyethanol 290.28
    tert-butanol 610.4
    MTBE 127.17
    2-butoxyethanol 125.57
    propionic acid 250.24
    o-xylene 17.28
    formic acid 351.58
    diethyl ether 86.36
    m-xylene 19.03
    p-xylene 18.22
    chlorobenzene 41.32
    dimethyl carbonate 72.25
    n-octane 0.82
    formamide 571.34
    cyclopentanone 343.06
    2-pentanone 191.38
    anisole 71.31
    cyclopentyl methyl ether 118.04
    gamma-butyrolactone 396.73
    1-methoxy-2-propanol 601.72
    pyridine 143.92
    3-pentanone 77.46
    furfural 258.02
    n-dodecane 1.59
    diethylene glycol 389.6
    diisopropyl ether 15.28
    tert-amyl alcohol 229.19
    acetylacetone 306.22
    n-hexadecane 1.77
    acetophenone 76.95
    methyl propionate 155.2
    isopentyl acetate 73.2
    trichloroethylene 246.52
    n-nonanol 37.85
    cyclohexanol 143.85
    benzyl alcohol 98.35
    2-ethylhexanol 35.49
    isooctanol 34.41
    dipropyl ether 25.13
    1,2-dichlorobenzene 42.46
    ethyl lactate 80.22
    propylene carbonate 155.74
    n-methylformamide 377.82
    2-pentanol 98.96
    n-pentane 0.41
    1-propoxy-2-propanol 145.23
    1-methoxy-2-propyl acetate 121.12
    2-(2-methoxypropoxy) propanol 129.63
    mesitylene 12.12
    ε-caprolactone 196.3
    p-cymene 11.94
    epichlorohydrin 480.64
    1,1,1-trichloroethane 76.76
    2-aminoethanol 495.72
    morpholine-4-carbaldehyde 325.33
    sulfolane 441.18
    2,2,4-trimethylpentane 1.51
    2-methyltetrahydrofuran 245.45
    n-hexyl acetate 67.2
    isooctane 1.35
    2-(2-butoxyethoxy)ethanol 197.4
    sec-butyl acetate 57.18
    tert-butyl acetate 130.74
    decalin 2.38
    glycerin 446.53
    diglyme 368.12
    acrylic acid 188.49
    isopropyl myristate 28.84
    n-butyric acid 311.12
    acetyl acetate 141.36
    di(2-ethylhexyl) phthalate 39.05
    ethyl propionate 74.24
    nitromethane 980.42
    1,2-diethoxyethane 123.84
    benzonitrile 75.96
    trioctyl phosphate 27.92
    1-bromopropane 36.42
    gamma-valerolactone 487.85
    n-decanol 28.99
    triethyl phosphate 35.41
    4-methyl-2-pentanol 50.38
    propionitrile 130.9
    vinylene carbonate 136.38
    1,1,2-trichlorotrifluoroethane 296.47
    DMS 73.31
    cumene 12.24
    2-octanol 25.12
    2-hexanone 93.16
    octyl acetate 38.18
    limonene 17.13
    1,2-dimethoxyethane 510.29
    ethyl orthosilicate 32.89
    tributyl phosphate 34.27
    diacetone alcohol 232.91
    N,N-dimethylaniline 41.9
    acrylonitrile 183.9
    aniline 70.48
    1,3-propanediol 719.18
    bromobenzene 31.18
    dibromomethane 90.82
    1,1,2,2-tetrachloroethane 204.23
    2-methyl-cyclohexyl acetate 53.64
    tetrabutyl urea 45.16
    diisobutyl methanol 24.14
    2-phenylethanol 75.16
    styrene 17.92
    dioctyl adipate 53.9
    dimethyl sulfate 130.74
    ethyl butyrate 53.55
    methyl lactate 131.17
    butyl lactate 59.62
    diethyl carbonate 43.88
    propanediol butyl ether 144.99
    triethyl orthoformate 43.35
    p-tert-butyltoluene 12.16
    methyl 4-tert-butylbenzoate 77.3
    morpholine 816.05
    tert-butylamine 119.83
    n-dodecanol 21.92
    dimethoxymethane 413.47
    ethylene carbonate 126.28
    cyrene 120.82
    2-ethoxyethyl acetate 97.92
    2-ethylhexyl acetate 46.57
    1,2,4-trichlorobenzene 52.81
    4-methylpyridine 110.48
    dibutyl ether 33.5
    2,6-dimethyl-4-heptanol 24.14
    DEF 135.11
    dimethyl isosorbide 177.47
    tetrachloroethylene 109.07
    eugenol 89.83
    triacetin 95.72
    span 80 101.02
    1,4-butanediol 213.78
    1,1-dichloroethane 109.54
    2-methyl-1-pentanol 94.92
    methyl formate 275.54
    2-methyl-1-butanol 121.02
    n-decane 2.31
    butyronitrile 139.43
    3,7-dimethyl-1-octanol 41.04
    1-chlorooctane 14.42
    1-chlorotetradecane 6.44
    n-nonane 1.77
    undecane 1.86
    tert-butylcyclohexane 2.28
    cyclooctane 0.74
    cyclopentanol 178.53
    tetrahydropyran 315.59
    tert-amyl methyl ether 65.11
    2,5,8-trioxanonane 264.08
    1-hexene 5.3
    2-isopropoxyethanol 236.24
    2,2,2-trifluoroethanol 152.86
    methyl butyrate 113.7

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction