4-Ethylsyringol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    14059-92-8

    Molecular formula
    C10H14O3

    SMILES
    CCC1=CC(=C(C(=C1)OC)O)OC

  • Odor profile

    Fragrance
    Spicy 80.86%
    Phenolic 78.47%
    Smoky 69.46%
    Woody 55.99%
    Burnt 51.18%
    Vanilla 48.69%
    Clove 45.27%
    Medicinal 44.18%
    Balsamic 40.3%
    Leathery 37.56%

     

    Flavor
    Phenolic 61.6%
    Spice 52.84%
    Smoky 50.48%
    Bacon 43.26%
    Smoke 41.67%
    Woody 40.93%
    Medicinal 38.45%
    Spicy 36.79%
    Clove 31.96%
    Vanilla 31.55%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.5

    pKa est.
    9.73 (weak base)

    Molecular weight
    182.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point

    • 106.00 °C. @ 2.00 mm Hg

    Flash point

    • 110.03 ˚C est.

    Solubility expt.

    • insoluble in water; soluble in fat
    • miscible (in ethanol)

  • Synonyms

    • 4-Ethylsyringol
    • 4-Ethyl-2,6-dimethoxyphenol
    • 14059-92-8
    • 2,6-Dimethoxy-4-ethylphenol
    • Phenol, 4-ethyl-2,6-dimethoxy-
    • FEMA No. 3671
    • Phenol, 4-ethyl-2,6-dimethoxy
    • 4-Ethylpyrogallol dimethyl ether
    • 1-Ethyl-3,5-dimethoxy-4-hydroxybenzene
    • UNII-1T2NOI6FZ9
    • 4-Hydroxy-3,5-dimethoxyethylbenzene
    • 4-Hydroxy-3,5-dimethoxyphenylethane
    • 1T2NOI6FZ9
    • 4-ethyl-2,6-dimethoxy-phenol
    • DTXSID5075072
    • FEMA 3671
    • 4-Ethyl-2,6-dimethoxyphenol, 9CI
    • PHENOL, 2,6-DIMETHOXY-4-ETHYL-
    • 4-ETHYL-2,6-DIMETHOXYPHENOL [FHFI]
    • Phenol,4-ethyl-2,6-dimethoxy-
    • MFCD01366571
    • SCHEMBL901445
    • DTXCID1034557
    • CHEBI:179568
    • PAA05992
    • AKOS022641090
    • AS-77648
    • NS00124379
    • D93071
    • EN300-261431
    • Q27252847
    • 639-043-0

  • Applications

    4-Ethylsyringol (CAS 14059-92-8) is a substituted phenol that is typically considered a fragrance-related material and an intermediate for aroma chemistry. In perfumery, it can serve as an odorant and a building block for synthesizing more complex fragrance notes. It is also evaluated for use in cosmetics/personal care as a fragrance ingredient, and may appear in household products and cleaners as a scent additive. In industrial manufacturing, it can act as a specialty intermediate in the synthesis of aroma compounds and related derivatives, and may be employed as a fragrance-related component in coatings/inks and polymer formulations. Overall, its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 276.27
    methanol 292.03
    isopropanol 142.87
    water 1.23
    ethyl acetate 153.28
    n-propanol 187.93
    acetone 319.19
    n-butanol 134.04
    acetonitrile 218.65
    DMF 604.67
    toluene 59.89
    isobutanol 106.9
    1,4-dioxane 449.15
    methyl acetate 246.08
    THF 438.25
    2-butanone 207.02
    n-pentanol 114.84
    sec-butanol 120.55
    n-hexane 4.95
    ethylene glycol 238.78
    NMP 271.18
    cyclohexane 21.56
    DMSO 643.77
    n-butyl acetate 103.17
    n-octanol 73.07
    chloroform 583.06
    n-propyl acetate 112.71
    acetic acid 306.05
    dichloromethane 736.29
    cyclohexanone 264.55
    propylene glycol 146.16
    isopropyl acetate 66.58
    DMAc 270.74
    2-ethoxyethanol 301.88
    isopentanol 82.71
    n-heptane 10.13
    ethyl formate 297.29
    1,2-dichloroethane 406.97
    n-hexanol 112.23
    2-methoxyethanol 541.71
    isobutyl acetate 62.7
    tetrachloromethane 105.81
    n-pentyl acetate 75.96
    transcutol 252.58
    n-heptanol 79.26
    ethylbenzene 45.05
    MIBK 57.76
    2-propoxyethanol 231.68
    tert-butanol 175.07
    MTBE 90.18
    2-butoxyethanol 150.48
    propionic acid 188.45
    o-xylene 50.37
    formic acid 158.99
    diethyl ether 89.2
    m-xylene 41.83
    p-xylene 64.01
    chlorobenzene 138.75
    dimethyl carbonate 97.46
    n-octane 7.91
    formamide 305.1
    cyclopentanone 333.73
    2-pentanone 112.99
    anisole 114.31
    cyclopentyl methyl ether 100.69
    gamma-butyrolactone 439.42
    1-methoxy-2-propanol 246.72
    pyridine 319.55
    3-pentanone 88.35
    furfural 476.93
    n-dodecane 8.33
    diethylene glycol 282.0
    diisopropyl ether 20.56
    tert-amyl alcohol 123.91
    acetylacetone 166.1
    n-hexadecane 9.52
    acetophenone 119.52
    methyl propionate 147.26
    isopentyl acetate 86.12
    trichloroethylene 720.36
    n-nonanol 65.04
    cyclohexanol 120.86
    benzyl alcohol 143.88
    2-ethylhexanol 68.74
    isooctanol 59.2
    dipropyl ether 53.01
    1,2-dichlorobenzene 148.03
    ethyl lactate 92.36
    propylene carbonate 245.96
    n-methylformamide 396.53
    2-pentanol 60.3
    n-pentane 5.68
    1-propoxy-2-propanol 127.79
    1-methoxy-2-propyl acetate 102.16
    2-(2-methoxypropoxy) propanol 100.2
    mesitylene 28.33
    ε-caprolactone 212.07
    p-cymene 42.21
    epichlorohydrin 500.4
    1,1,1-trichloroethane 273.74
    2-aminoethanol 231.11
    morpholine-4-carbaldehyde 335.2
    sulfolane 470.58
    2,2,4-trimethylpentane 5.94
    2-methyltetrahydrofuran 199.97
    n-hexyl acetate 97.81
    isooctane 4.68
    2-(2-butoxyethoxy)ethanol 153.68
    sec-butyl acetate 53.19
    tert-butyl acetate 70.36
    decalin 12.49
    glycerin 233.63
    diglyme 309.55
    acrylic acid 211.32
    isopropyl myristate 43.16
    n-butyric acid 201.16
    acetyl acetate 110.6
    di(2-ethylhexyl) phthalate 57.74
    ethyl propionate 81.43
    nitromethane 609.81
    1,2-diethoxyethane 95.72
    benzonitrile 183.58
    trioctyl phosphate 46.93
    1-bromopropane 126.1
    gamma-valerolactone 416.84
    n-decanol 52.27
    triethyl phosphate 59.39
    4-methyl-2-pentanol 32.67
    propionitrile 160.74
    vinylene carbonate 289.23
    1,1,2-trichlorotrifluoroethane 450.4
    DMS 83.94
    cumene 35.45
    2-octanol 50.81
    2-hexanone 95.81
    octyl acetate 60.34
    limonene 54.01
    1,2-dimethoxyethane 391.74
    ethyl orthosilicate 52.06
    tributyl phosphate 48.72
    diacetone alcohol 117.2
    N,N-dimethylaniline 73.65
    acrylonitrile 269.41
    aniline 109.86
    1,3-propanediol 291.66
    bromobenzene 140.66
    dibromomethane 388.37
    1,1,2,2-tetrachloroethane 507.36
    2-methyl-cyclohexyl acetate 79.34
    tetrabutyl urea 63.03
    diisobutyl methanol 39.72
    2-phenylethanol 123.92
    styrene 59.76
    dioctyl adipate 74.32
    dimethyl sulfate 154.99
    ethyl butyrate 83.79
    methyl lactate 115.61
    butyl lactate 74.43
    diethyl carbonate 80.8
    propanediol butyl ether 128.95
    triethyl orthoformate 65.06
    p-tert-butyltoluene 39.3
    methyl 4-tert-butylbenzoate 108.74
    morpholine 412.18
    tert-butylamine 82.47
    n-dodecanol 42.21
    dimethoxymethane 277.8
    ethylene carbonate 221.32
    cyrene 133.69
    2-ethoxyethyl acetate 101.88
    2-ethylhexyl acetate 65.42
    1,2,4-trichlorobenzene 172.29
    4-methylpyridine 205.66
    dibutyl ether 51.94
    2,6-dimethyl-4-heptanol 39.72
    DEF 154.25
    dimethyl isosorbide 167.96
    tetrachloroethylene 371.98
    eugenol 120.03
    triacetin 100.38
    span 80 99.03
    1,4-butanediol 140.37
    1,1-dichloroethane 269.94
    2-methyl-1-pentanol 81.76
    methyl formate 397.09
    2-methyl-1-butanol 85.79
    n-decane 12.08
    butyronitrile 153.06
    3,7-dimethyl-1-octanol 54.51
    1-chlorooctane 45.89
    1-chlorotetradecane 22.49
    n-nonane 11.14
    undecane 9.85
    tert-butylcyclohexane 10.56
    cyclooctane 7.41
    cyclopentanol 154.04
    tetrahydropyran 230.66
    tert-amyl methyl ether 59.92
    2,5,8-trioxanonane 198.16
    1-hexene 23.56
    2-isopropoxyethanol 150.4
    2,2,2-trifluoroethanol 141.38
    methyl butyrate 137.56

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction