4'-Ethylacetophenone

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    937-30-4

    Molecular formula
    C10H12O

    SMILES
    CCC1=CC=C(C=C1)C(=O)C

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Sweet 84.38%
    Floral 78.95%
    Herbal 66.49%
    Anisic 53.76%
    Hawthorn 52.41%
    Hay 49.68%
    Cherry 49.33%
    Balsamic 45.52%
    Powdery 44.94%
    Coumarinic 43.69%

    Scent© AI

  • Properties

    XLogP3-AA
    2.5

    Molecular weight
    148.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point est.
    233°C

    Flash point est.
    93.24 ˚C

  • Synonyms

    • 4'-Ethylacetophenone
    • 937-30-4
    • 1-(4-Ethylphenyl)ethanone
    • 4-ETHYLACETOPHENONE
    • p-Ethylacetophenone
    • Ethanone, 1-(4-ethylphenyl)-
    • Acetophenone, 4'-ethyl-
    • p-Acetylethylbenzene
    • p-Ethylphenyl methyl ketone
    • 1-acetyl-4-ethylbenzene
    • LSA7B53YDO
    • MFCD00009262
    • NSC 6768
    • NSC-6768
    • EINECS 213-326-5
    • UNII-LSA7B53YDO
    • AI3-08507
    • 1-(4-ethylphenyl)ethan-1-one
    • DTXSID5061326
    • NSC6768
    • p-Ethylaceto-phenone
    • acetophenone, p-ethyl-
    • 4'-Ethylacetophenone, 97%
    • SCHEMBL334751
    • 1-(4-Ethylphenyl)ethanone #
    • DTXCID6048880
    • Acetophenone, 4'-ethyl-(8CI)
    • CHEBI:195891
    • BBL027748
    • STL281972
    • AKOS000120514
    • CS-W021233
    • FE61851
    • AC-10913
    • AS-14580
    • SY049093
    • E0318
    • NS00012367
    • 4 inverted exclamation mark -Ethylacetophenone
    • EN300-20966
    • Q63398062
    • F0001-2255
    • Z104485556

  • Applications

    4'-Ethylacetophenone (CAS 937-30-4) is an aromatic ketone widely used as a versatile intermediate and building block: it forms chalcones via condensation with aromatic aldehydes that can be elaborated into flavonoids and heterocycles such as pyrazolines, isoxazoles, and pyrimidines for pharmaceutical and agrochemical research; it serves as a scaffold for transformations including reduction to secondary alcohols, oxime/hydrazone formation, and carbon-framework diversification (Wittig, Grignard) to tune lipophilicity and material properties; it is a precursor to aryl-ketone aroma chemicals and is employed in the synthesis of photoinitiators and UV absorbers for UV-curable coatings, inks, and resins; it is also used as a reference standard and model substrate to probe reactions of aryl methyl ketones (haloform, chemoselective reductions, electrophilic substitution shaped by ethyl and carbonyl directing effects); additionally it offers a convenient entry to 4-ethylbenzoic acid, chalcone-type dyes/pigments, polymer additives, and advanced materials, making it relevant across pharmaceutical, agrochemical, flavor–fragrance, surface-coatings, and electronics supply chains.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 600.3
    methanol 835.55
    isopropanol 320.72
    water 1.31
    ethyl acetate 1172.57
    n-propanol 521.72
    acetone 1151.84
    n-butanol 435.31
    acetonitrile 1357.57
    DMF 1818.7
    toluene 700.26
    isobutanol 318.83
    1,4-dioxane 2069.52
    methyl acetate 1082.3
    THF 1341.73
    2-butanone 1085.07
    n-pentanol 335.4
    sec-butanol 333.83
    n-hexane 95.69
    ethylene glycol 145.35
    NMP 1703.01
    cyclohexane 143.11
    DMSO 1552.13
    n-butyl acetate 671.47
    n-octanol 95.13
    chloroform 2988.22
    n-propyl acetate 539.39
    acetic acid 706.81
    dichloromethane 3106.5
    cyclohexanone 1408.6
    propylene glycol 144.74
    isopropyl acetate 516.24
    DMAc 1343.81
    2-ethoxyethanol 536.37
    isopentanol 379.91
    n-heptane 24.42
    ethyl formate 547.34
    1,2-dichloroethane 2330.54
    n-hexanol 328.79
    2-methoxyethanol 850.79
    isobutyl acetate 289.83
    tetrachloromethane 409.52
    n-pentyl acetate 262.92
    transcutol 3406.64
    n-heptanol 108.31
    ethylbenzene 306.64
    MIBK 365.71
    2-propoxyethanol 611.22
    tert-butanol 471.22
    MTBE 705.73
    2-butoxyethanol 279.54
    propionic acid 575.2
    o-xylene 320.03
    formic acid 347.97
    diethyl ether 1107.93
    m-xylene 341.02
    p-xylene 343.85
    chlorobenzene 1158.31
    dimethyl carbonate 391.88
    n-octane 7.29
    formamide 796.12
    cyclopentanone 1398.53
    2-pentanone 753.11
    anisole 797.64
    cyclopentyl methyl ether 797.6
    gamma-butyrolactone 1555.67
    1-methoxy-2-propanol 464.6
    pyridine 1962.22
    3-pentanone 755.59
    furfural 1418.4
    n-dodecane 5.13
    diethylene glycol 434.61
    diisopropyl ether 205.85
    tert-amyl alcohol 414.52
    acetylacetone 837.71
    n-hexadecane 6.38
    acetophenone 584.24
    methyl propionate 847.29
    isopentyl acetate 543.3
    trichloroethylene 3893.48
    n-nonanol 87.72
    cyclohexanol 452.73
    benzyl alcohol 459.51
    2-ethylhexanol 188.48
    isooctanol 89.49
    dipropyl ether 286.72
    1,2-dichlorobenzene 913.8
    ethyl lactate 178.64
    propylene carbonate 751.28
    n-methylformamide 939.98
    2-pentanol 241.96
    n-pentane 59.27
    1-propoxy-2-propanol 371.73
    1-methoxy-2-propyl acetate 627.09
    2-(2-methoxypropoxy) propanol 397.15
    mesitylene 183.48
    ε-caprolactone 1087.75
    p-cymene 109.93
    epichlorohydrin 2067.35
    1,1,1-trichloroethane 1603.06
    2-aminoethanol 307.71
    morpholine-4-carbaldehyde 1636.12
    sulfolane 1506.82
    2,2,4-trimethylpentane 32.48
    2-methyltetrahydrofuran 1230.58
    n-hexyl acetate 388.34
    isooctane 23.11
    2-(2-butoxyethoxy)ethanol 548.0
    sec-butyl acetate 350.77
    tert-butyl acetate 547.6
    decalin 70.81
    glycerin 228.02
    diglyme 1236.49
    acrylic acid 533.08
    isopropyl myristate 122.79
    n-butyric acid 638.82
    acetyl acetate 604.41
    di(2-ethylhexyl) phthalate 137.73
    ethyl propionate 518.6
    nitromethane 1749.2
    1,2-diethoxyethane 947.27
    benzonitrile 740.55
    trioctyl phosphate 77.94
    1-bromopropane 947.4
    gamma-valerolactone 1659.71
    n-decanol 60.11
    triethyl phosphate 190.23
    4-methyl-2-pentanol 148.04
    propionitrile 886.86
    vinylene carbonate 778.93
    1,1,2-trichlorotrifluoroethane 1133.87
    DMS 565.17
    cumene 158.57
    2-octanol 64.09
    2-hexanone 553.85
    octyl acetate 151.92
    limonene 163.79
    1,2-dimethoxyethane 1119.56
    ethyl orthosilicate 192.63
    tributyl phosphate 142.48
    diacetone alcohol 457.76
    N,N-dimethylaniline 394.66
    acrylonitrile 1157.99
    aniline 871.41
    1,3-propanediol 372.71
    bromobenzene 1252.4
    dibromomethane 1845.63
    1,1,2,2-tetrachloroethane 2754.04
    2-methyl-cyclohexyl acetate 288.31
    tetrabutyl urea 166.15
    diisobutyl methanol 103.23
    2-phenylethanol 405.64
    styrene 513.25
    dioctyl adipate 220.17
    dimethyl sulfate 625.72
    ethyl butyrate 403.29
    methyl lactate 258.26
    butyl lactate 201.06
    diethyl carbonate 308.85
    propanediol butyl ether 261.41
    triethyl orthoformate 281.77
    p-tert-butyltoluene 108.12
    methyl 4-tert-butylbenzoate 285.3
    morpholine 2099.63
    tert-butylamine 332.06
    n-dodecanol 43.93
    dimethoxymethane 904.64
    ethylene carbonate 664.12
    cyrene 346.44
    2-ethoxyethyl acetate 548.82
    2-ethylhexyl acetate 439.94
    1,2,4-trichlorobenzene 1103.29
    4-methylpyridine 1788.45
    dibutyl ether 228.06
    2,6-dimethyl-4-heptanol 103.23
    DEF 1111.33
    dimethyl isosorbide 681.93
    tetrachloroethylene 1808.9
    eugenol 315.71
    triacetin 417.47
    span 80 265.86
    1,4-butanediol 137.52
    1,1-dichloroethane 1726.01
    2-methyl-1-pentanol 333.59
    methyl formate 622.41
    2-methyl-1-butanol 388.52
    n-decane 9.57
    butyronitrile 691.01
    3,7-dimethyl-1-octanol 124.88
    1-chlorooctane 83.11
    1-chlorotetradecane 28.82
    n-nonane 9.18
    undecane 6.61
    tert-butylcyclohexane 59.54
    cyclooctane 36.21
    cyclopentanol 375.8
    tetrahydropyran 1557.19
    tert-amyl methyl ether 475.18
    2,5,8-trioxanonane 735.75
    1-hexene 330.01
    2-isopropoxyethanol 347.84
    2,2,2-trifluoroethanol 265.48
    methyl butyrate 643.97

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Fern, sweet 1 Comptonia peregrina (L.) Coulter, fam. Pteridophytae 1.0%
Fern, sweet 2 Comptonia peregrina (L.) Coulter, fam. Pteridophytae 1.42%
Genet headspace 2 8023-80-1 Spartium junceum L., fam. Leguminosae (Papilionaceae) 0.01%
Cymbidium sinense flower headspace (China) Cymbidium sinense (Andr.) Willd., fam. Orchidaceae 0.5%