4-Ethyl-5-pentyloxazole

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  • Identifiers

    CAS number
    79886-43-4

    Molecular formula
    C10H17NO

    SMILES
    CCCCCC1=C(N=CO1)CC

    Safety labels

  • Odor profile

    Fragrance
    Green 83.51%
    Vegetable 55.41%
    Fatty 51.25%
    Earthy 48.39%
    Nutty 44.92%
    Roasted 42.91%
    Meaty 36.57%
    Herbal 32.86%
    Musty 30.92%
    Fruity 29.99%

     

    Flavor
    Green 81.79%
    Earthy 52.64%
    Fatty 50.68%
    Nutty 47.55%
    Vegetable 44.64%
    Fruity 44.4%
    Pepper 44.02%
    Herbal 42.22%
    Roasted 35.39%
    Mushroom 34.78%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    3.4

    pKa est.
    7.43 (neutral)

    Molecular weight
    167.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point est.
    223°C

    Flash point

    • 90.34 ˚C est.

  • Synonyms

    • 4-Ethyl-5-pentyloxazole
    • 4-ethyl-5-pentyl-1,3-oxazole
    • 79886-43-4
    • RefChem:98883
    • SCHEMBL8847833
    • CHEBI:195842
    • DTXSID901313506
    • 79886-43-4

  • Applications

    4-Ethyl-5-pentyloxazole is used primarily as a synthetic intermediate and heterocyclic building block in the preparation of fine chemicals, notably in pharmaceutical and agrochemical synthesis. It also serves as a precursor or motif in dyes, pigments, and specialty polymers, where the oxazole ring contributes to performance in coatings and plastics. In coatings and inks, it can function as a functionalized unit affecting thermal stability and adhesion properties. Additionally, it may be explored as a scaffold in fragrance chemistry, with use subject to formulation constraints and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 10608.67
    methanol 14778.17
    isopropanol 7216.1
    water 0.83
    ethyl acetate 8134.79
    n-propanol 8147.28
    acetone 12249.22
    n-butanol 7571.57
    acetonitrile 8870.19
    DMF 10266.6
    toluene 3409.49
    isobutanol 6859.55
    1,4-dioxane 8244.3
    methyl acetate 5794.42
    THF 9905.2
    2-butanone 7461.63
    n-pentanol 4386.33
    sec-butanol 5847.95
    n-hexane 1059.81
    ethylene glycol 897.85
    NMP 5889.07
    cyclohexane 1833.01
    DMSO 7445.14
    n-butyl acetate 6828.01
    n-octanol 1341.56
    chloroform 16861.96
    n-propyl acetate 4103.68
    acetic acid 6056.92
    dichloromethane 18505.42
    cyclohexanone 11074.46
    propylene glycol 1274.14
    isopropyl acetate 4833.53
    DMAc 4728.67
    2-ethoxyethanol 3923.88
    isopentanol 6142.95
    n-heptane 406.65
    ethyl formate 4987.98
    1,2-dichloroethane 11602.64
    n-hexanol 4336.55
    2-methoxyethanol 7474.31
    isobutyl acetate 2551.27
    tetrachloromethane 2817.55
    n-pentyl acetate 2961.02
    transcutol 8510.25
    n-heptanol 1323.67
    ethylbenzene 1442.21
    MIBK 3430.64
    2-propoxyethanol 5125.38
    tert-butanol 6545.33
    MTBE 7945.27
    2-butoxyethanol 2244.02
    propionic acid 4044.56
    o-xylene 1426.37
    formic acid 1610.56
    diethyl ether 9434.75
    m-xylene 1796.72
    p-xylene 1897.27
    chlorobenzene 5037.09
    dimethyl carbonate 1669.15
    n-octane 171.84
    formamide 2474.37
    cyclopentanone 8450.86
    2-pentanone 7165.0
    anisole 2517.49
    cyclopentyl methyl ether 5352.68
    gamma-butyrolactone 8152.3
    1-methoxy-2-propanol 4688.76
    pyridine 9160.59
    3-pentanone 4409.99
    furfural 5759.68
    n-dodecane 125.18
    diethylene glycol 2376.97
    diisopropyl ether 2030.07
    tert-amyl alcohol 4950.39
    acetylacetone 5167.62
    n-hexadecane 149.83
    acetophenone 2067.62
    methyl propionate 4844.24
    isopentyl acetate 5105.4
    trichloroethylene 18321.93
    n-nonanol 1090.82
    cyclohexanol 5765.35
    benzyl alcohol 2245.38
    2-ethylhexanol 2058.52
    isooctanol 1067.63
    dipropyl ether 2792.52
    1,2-dichlorobenzene 3559.64
    ethyl lactate 936.55
    propylene carbonate 4402.39
    n-methylformamide 5148.38
    2-pentanol 4515.71
    n-pentane 942.28
    1-propoxy-2-propanol 3430.87
    1-methoxy-2-propyl acetate 3179.16
    2-(2-methoxypropoxy) propanol 1310.41
    mesitylene 1018.84
    ε-caprolactone 7209.94
    p-cymene 705.83
    epichlorohydrin 10299.73
    1,1,1-trichloroethane 9249.81
    2-aminoethanol 2369.24
    morpholine-4-carbaldehyde 5054.78
    sulfolane 6453.87
    2,2,4-trimethylpentane 393.45
    2-methyltetrahydrofuran 8521.59
    n-hexyl acetate 3252.1
    isooctane 326.58
    2-(2-butoxyethoxy)ethanol 2089.64
    sec-butyl acetate 2581.33
    tert-butyl acetate 3691.45
    decalin 541.84
    glycerin 1223.96
    diglyme 3969.24
    acrylic acid 3031.0
    isopropyl myristate 928.2
    n-butyric acid 8202.88
    acetyl acetate 3412.05
    di(2-ethylhexyl) phthalate 744.62
    ethyl propionate 3108.83
    nitromethane 8111.99
    1,2-diethoxyethane 5178.53
    benzonitrile 3862.3
    trioctyl phosphate 576.79
    1-bromopropane 8134.74
    gamma-valerolactone 8908.1
    n-decanol 723.0
    triethyl phosphate 717.07
    4-methyl-2-pentanol 1919.71
    propionitrile 7378.26
    vinylene carbonate 4103.51
    1,1,2-trichlorotrifluoroethane 4562.45
    DMS 1976.66
    cumene 832.41
    2-octanol 1043.84
    2-hexanone 4078.55
    octyl acetate 1187.78
    limonene 1342.25
    1,2-dimethoxyethane 7428.44
    ethyl orthosilicate 816.28
    tributyl phosphate 844.01
    diacetone alcohol 2627.59
    N,N-dimethylaniline 1378.08
    acrylonitrile 7400.37
    aniline 3919.54
    1,3-propanediol 3746.34
    bromobenzene 5877.75
    dibromomethane 11961.66
    1,1,2,2-tetrachloroethane 12355.21
    2-methyl-cyclohexyl acetate 1489.1
    tetrabutyl urea 1050.86
    diisobutyl methanol 958.45
    2-phenylethanol 2194.18
    styrene 2297.03
    dioctyl adipate 1082.09
    dimethyl sulfate 1804.17
    ethyl butyrate 2907.27
    methyl lactate 1276.73
    butyl lactate 1509.66
    diethyl carbonate 1542.88
    propanediol butyl ether 1614.37
    triethyl orthoformate 1505.78
    p-tert-butyltoluene 637.91
    methyl 4-tert-butylbenzoate 1273.82
    morpholine 10773.7
    tert-butylamine 4559.3
    n-dodecanol 510.47
    dimethoxymethane 5851.1
    ethylene carbonate 3928.96
    cyrene 1043.47
    2-ethoxyethyl acetate 3143.25
    2-ethylhexyl acetate 3639.33
    1,2,4-trichlorobenzene 3569.98
    4-methylpyridine 9522.16
    dibutyl ether 2435.51
    2,6-dimethyl-4-heptanol 958.45
    DEF 7413.64
    dimethyl isosorbide 2177.45
    tetrachloroethylene 8602.84
    eugenol 1331.31
    triacetin 1634.76
    span 80 1360.6
    1,4-butanediol 1364.02
    1,1-dichloroethane 12153.78
    2-methyl-1-pentanol 3704.45
    methyl formate 3832.52
    2-methyl-1-butanol 5730.5
    n-decane 221.54
    butyronitrile 9113.97
    3,7-dimethyl-1-octanol 1339.56
    1-chlorooctane 1117.0
    1-chlorotetradecane 365.65
    n-nonane 229.38
    undecane 159.28
    tert-butylcyclohexane 480.14
    cyclooctane 399.28
    cyclopentanol 4783.84
    tetrahydropyran 11688.2
    tert-amyl methyl ether 3960.23
    2,5,8-trioxanonane 2098.82
    1-hexene 3799.35
    2-isopropoxyethanol 2488.68
    2,2,2-trifluoroethanol 1384.04
    methyl butyrate 5110.09

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction