4-Cyclopentadecen-1-one

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  • Identifiers

    CAS number
    35720-57-1

    Molecular formula
    C15H26O

    SMILES
    C1CCCCCC(=O)CC/C=C/CCCC1

    Safety labels

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Musk 90.22%
    Animal 65.49%
    Powdery 63.42%
    Amber 49.74%
    Dry 44.62%
    Natural 42.27%
    Clean 38.35%
    Floral 35.59%
    Balsamic 35.07%
    Sweet 33.1%

     

    Flavor
    Animal 30.28%
    Minty 25.71%
    Fruity 24.23%
    Shrimp 22.15%
    Camphor 21.87%
    Ammoniacal 20.66%
    Alkaline 20.05%
    Musk 19.52%
    Beet 19.11%
    Terpentine 18.95%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    5.2

    pKa est.
    9.86 (weak base)

    Molecular weight
    222.37 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    314°C

    Flash point

    • 140.98 ˚C est.

  • Synonyms

    • 4-Cyclopentadecen-1-one
    • RefChem:912461
    • 35720-57-1
    • cyclopentadec-4E-en-1-one
    • SCHEMBL236423
    • 35720-57-1

  • Applications

    4-Cyclopentadecen-1-one (CAS 35720-57-1) is a macrocyclic ketone widely used in perfumery as a musk-like base note and a fixative, contributing a long-lasting aroma in fragrances. In cosmetics and personal care, it serves as a fragrance ingredient to impart depth and longevity to lotions, creams, and other personal-care products. In household products, it is used in air fresheners and scented cleaners to provide a characteristic musky scent. In coatings, inks, and polymers, it can function as a fragrance additive or odor-release component to enhance product scent branding; it is sometimes explored as an intermediate in fragrance synthesis. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 751.65
    methanol 483.24
    isopropanol 858.44
    water 0.03
    ethyl acetate 1782.33
    n-propanol 799.3
    acetone 1977.53
    n-butanol 873.58
    acetonitrile 899.34
    DMF 1619.31
    toluene 1137.77
    isobutanol 685.26
    1,4-dioxane 2167.95
    methyl acetate 1064.6
    THF 3034.58
    2-butanone 1570.1
    n-pentanol 570.51
    sec-butanol 816.39
    n-hexane 631.84
    ethylene glycol 63.18
    NMP 1433.13
    cyclohexane 1073.23
    DMSO 1648.54
    n-butyl acetate 1519.47
    n-octanol 346.26
    chloroform 3735.87
    n-propyl acetate 1165.77
    acetic acid 645.54
    dichloromethane 3115.13
    cyclohexanone 2541.26
    propylene glycol 160.65
    isopropyl acetate 1340.25
    DMAc 1278.01
    2-ethoxyethanol 649.63
    isopentanol 893.16
    n-heptane 366.35
    ethyl formate 630.32
    1,2-dichloroethane 2279.67
    n-hexanol 726.89
    2-methoxyethanol 988.54
    isobutyl acetate 811.6
    tetrachloromethane 670.35
    n-pentyl acetate 1003.44
    transcutol 4247.73
    n-heptanol 355.83
    ethylbenzene 567.45
    MIBK 1081.93
    2-propoxyethanol 1035.6
    tert-butanol 1146.59
    MTBE 1711.01
    2-butoxyethanol 670.95
    propionic acid 632.62
    o-xylene 612.32
    formic acid 95.53
    diethyl ether 2257.58
    m-xylene 681.92
    p-xylene 660.1
    chlorobenzene 1292.76
    dimethyl carbonate 371.18
    n-octane 103.87
    formamide 176.64
    cyclopentanone 2373.85
    2-pentanone 1671.31
    anisole 844.63
    cyclopentyl methyl ether 1931.15
    gamma-butyrolactone 2137.9
    1-methoxy-2-propanol 1019.65
    pyridine 2174.16
    3-pentanone 1320.27
    furfural 1575.03
    n-dodecane 56.56
    diethylene glycol 466.32
    diisopropyl ether 793.35
    tert-amyl alcohol 909.87
    acetylacetone 1581.36
    n-hexadecane 69.63
    acetophenone 734.17
    methyl propionate 1106.03
    isopentyl acetate 1286.29
    trichloroethylene 3427.88
    n-nonanol 322.47
    cyclohexanol 1132.65
    benzyl alcohol 544.53
    2-ethylhexanol 610.48
    isooctanol 351.22
    dipropyl ether 1394.62
    1,2-dichlorobenzene 1158.69
    ethyl lactate 354.41
    propylene carbonate 1189.16
    n-methylformamide 509.56
    2-pentanol 813.17
    n-pentane 406.65
    1-propoxy-2-propanol 982.57
    1-methoxy-2-propyl acetate 1142.38
    2-(2-methoxypropoxy) propanol 675.07
    mesitylene 485.61
    ε-caprolactone 1824.78
    p-cymene 346.57
    epichlorohydrin 2278.01
    1,1,1-trichloroethane 2197.69
    2-aminoethanol 215.52
    morpholine-4-carbaldehyde 1456.25
    sulfolane 2147.02
    2,2,4-trimethylpentane 153.74
    2-methyltetrahydrofuran 2448.74
    n-hexyl acetate 1122.78
    isooctane 147.56
    2-(2-butoxyethoxy)ethanol 1014.29
    sec-butyl acetate 899.37
    tert-butyl acetate 1327.36
    decalin 326.78
    glycerin 230.55
    diglyme 1923.91
    acrylic acid 435.66
    isopropyl myristate 433.12
    n-butyric acid 1324.27
    acetyl acetate 986.51
    di(2-ethylhexyl) phthalate 299.33
    ethyl propionate 1024.1
    nitromethane 1140.47
    1,2-diethoxyethane 1846.3
    benzonitrile 902.75
    trioctyl phosphate 229.25
    1-bromopropane 1795.66
    gamma-valerolactone 2420.72
    n-decanol 231.25
    triethyl phosphate 418.97
    4-methyl-2-pentanol 495.05
    propionitrile 1026.06
    vinylene carbonate 933.75
    1,1,2-trichlorotrifluoroethane 1370.42
    DMS 723.19
    cumene 358.32
    2-octanol 281.45
    2-hexanone 1104.3
    octyl acetate 485.53
    limonene 633.43
    1,2-dimethoxyethane 1534.65
    ethyl orthosilicate 435.33
    tributyl phosphate 334.55
    diacetone alcohol 965.86
    N,N-dimethylaniline 550.44
    acrylonitrile 985.81
    aniline 1028.01
    1,3-propanediol 468.1
    bromobenzene 1560.78
    dibromomethane 2310.15
    1,1,2,2-tetrachloroethane 3063.53
    2-methyl-cyclohexyl acetate 720.1
    tetrabutyl urea 409.44
    diisobutyl methanol 431.16
    2-phenylethanol 551.69
    styrene 781.33
    dioctyl adipate 589.68
    dimethyl sulfate 572.35
    ethyl butyrate 1079.45
    methyl lactate 372.48
    butyl lactate 584.15
    diethyl carbonate 631.9
    propanediol butyl ether 559.26
    triethyl orthoformate 768.98
    p-tert-butyltoluene 338.46
    methyl 4-tert-butylbenzoate 667.16
    morpholine 2450.92
    tert-butylamine 889.34
    n-dodecanol 181.1
    dimethoxymethane 1089.29
    ethylene carbonate 953.2
    cyrene 456.14
    2-ethoxyethyl acetate 1109.36
    2-ethylhexyl acetate 1025.85
    1,2,4-trichlorobenzene 1255.38
    4-methylpyridine 1890.43
    dibutyl ether 1150.5
    2,6-dimethyl-4-heptanol 431.16
    DEF 1608.6
    dimethyl isosorbide 1071.11
    tetrachloroethylene 2122.51
    eugenol 532.97
    triacetin 965.21
    span 80 670.49
    1,4-butanediol 151.05
    1,1-dichloroethane 2289.6
    2-methyl-1-pentanol 559.73
    methyl formate 366.46
    2-methyl-1-butanol 766.15
    n-decane 117.18
    butyronitrile 1185.33
    3,7-dimethyl-1-octanol 470.08
    1-chlorooctane 439.69
    1-chlorotetradecane 157.74
    n-nonane 125.35
    undecane 77.62
    tert-butylcyclohexane 251.61
    cyclooctane 341.91
    cyclopentanol 947.4
    tetrahydropyran 3167.59
    tert-amyl methyl ether 1148.35
    2,5,8-trioxanonane 1160.74
    1-hexene 1219.95
    2-isopropoxyethanol 613.74
    2,2,2-trifluoroethanol 206.85
    methyl butyrate 1270.44

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction