4-Butylresorcinol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    18979-61-8

    Molecular formula
    C10H14O2

    SMILES
    CCCCC1=C(C=C(C=C1)O)O

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Phenolic 80.63%
    Spicy 53.97%
    Smoky 52.37%
    Medicinal 49.58%
    Burnt 40.12%
    Leathery 33.77%
    Animal 33.71%
    Woody 32.84%
    Musty 29.41%
    Sweet 29.21%

     

    Flavor
    Phenolic 65.31%
    Medicinal 50.36%
    Spicy 35.68%
    Woody 33.44%
    Spice 31.79%
    Smoky 31.41%
    Phenol 31.08%
    Mild 30.4%
    Smoke 28.84%
    Bitter 26.91%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.4

    pKa est.
    10.6 (weak base)

    Molecular weight
    166.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    304°C

    Flash point

    • 145.13 ˚C est.

  • Synonyms

    • 4-Butylresorcinol
    • 18979-61-8
    • 4-butylbenzene-1,3-diol
    • Rucinol
    • 1,3-Benzenediol, 4-butyl-
    • 4-n-Butylresorcinol
    • Butylresorcinol
    • Resorcinol, 4-butyl-
    • 4-Butylresorcin
    • BRN 1942645
    • 2IK4UQ3ZGA
    • Rucinol (TN)
    • VIVINOL
    • DTXSID50172403
    • EC 606-191-2
    • 1,3-Dihydroxy-4-N butyl benzene
    • 4-06-00-06003 (Beilstein Handbook Reference)
    • 4-N-BUTYLRESORCINOL [WHO-DD]
    • RefChem:520646
    • DTXCID7094894
    • 4-BUTYLRESORCINOL [INCI]
    • 606-191-2
    • N-butylresorcinol
    • MFCD01684800
    • CHEMBL450195
    • UNII-2IK4UQ3ZGA
    • 4-Butyl-1,3-benzenediol
    • 2,4-Dihydroxy-N-butyl benzene
    • SCHEMBL68792
    • 4-Butylresorcinol (Standard)
    • 2,4-Dihydroxy-n-butylbenzene
    • orb1300048
    • SCHEMBL4656377
    • SCHEMBL29400052
    • CHEBI:81689
    • 4-Butylbenzene-1 pound not3-diol
    • HMS3749K09
    • AC-349
    • BDBM50248158
    • s4997
    • 4-Butylresorcinol, analytical standard
    • AKOS006277916
    • CCG-266331
    • CS-7786
    • HY-107369R
    • NCGC00599698-01
    • Rucinol; 2,4-Dihydroxy-n-butyl benzene
    • AS-10742
    • DA-60341
    • FB168030
    • SY054111
    • HY-107369
    • B3773
    • NS00006646
    • 4-Butylresorcinol;4-n-Butylresorcinol, Rucinol
    • C18343
    • 979D618
    • F214955
    • Q2171802
    • BRD-K61036791-001-01-6
    • 18979-61-8

  • Applications

    4-Butylresorcinol (CAS 18979-61-8) is used in cosmetics and personal care as a tyrosinase inhibitor for depigmenting skin formulations; it also serves as a chemical intermediate in the synthesis of resorcinol-derived colorants (dyes and pigments) and as a building block for pharmaceutical intermediates; in the polymers and plastics sector, it is used to prepare functional resorcinol derivatives and polymer additives; in coatings and inks, it functions as a precursor for color formulations and related pigment systems.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 5025.75
    methanol 4140.72
    isopropanol 3866.85
    water 0.2
    ethyl acetate 2706.22
    n-propanol 3929.74
    acetone 5724.43
    n-butanol 2677.42
    acetonitrile 2557.76
    DMF 4590.91
    toluene 186.98
    isobutanol 2319.13
    1,4-dioxane 2546.81
    methyl acetate 2457.85
    THF 5018.94
    2-butanone 2904.19
    n-pentanol 1294.85
    sec-butanol 2001.97
    n-hexane 38.07
    ethylene glycol 523.28
    NMP 1341.89
    cyclohexane 37.71
    DMSO 6124.73
    n-butyl acetate 1099.53
    n-octanol 279.22
    chloroform 613.98
    n-propyl acetate 943.87
    acetic acid 1327.08
    dichloromethane 709.63
    cyclohexanone 1951.6
    propylene glycol 1108.54
    isopropyl acetate 1130.22
    DMAc 1549.92
    2-ethoxyethanol 1336.35
    isopentanol 1633.31
    n-heptane 26.04
    ethyl formate 1084.84
    1,2-dichloroethane 877.15
    n-hexanol 1379.68
    2-methoxyethanol 3708.99
    isobutyl acetate 458.5
    tetrachloromethane 89.36
    n-pentyl acetate 322.97
    transcutol 2447.63
    n-heptanol 334.66
    ethylbenzene 93.11
    MIBK 987.59
    2-propoxyethanol 1959.6
    tert-butanol 3627.28
    MTBE 2192.22
    2-butoxyethanol 572.69
    propionic acid 1681.32
    o-xylene 105.96
    formic acid 330.99
    diethyl ether 1692.77
    m-xylene 178.76
    p-xylene 114.43
    chlorobenzene 282.89
    dimethyl carbonate 503.91
    n-octane 11.08
    formamide 984.1
    cyclopentanone 3347.38
    2-pentanone 2583.35
    anisole 389.43
    cyclopentyl methyl ether 1541.48
    gamma-butyrolactone 3137.47
    1-methoxy-2-propanol 2746.88
    pyridine 943.85
    3-pentanone 1134.44
    furfural 1022.11
    n-dodecane 11.34
    diethylene glycol 1095.22
    diisopropyl ether 351.98
    tert-amyl alcohol 1772.55
    acetylacetone 1642.14
    n-hexadecane 13.19
    acetophenone 295.46
    methyl propionate 1962.3
    isopentyl acetate 795.24
    trichloroethylene 1255.47
    n-nonanol 218.94
    cyclohexanol 963.28
    benzyl alcohol 329.52
    2-ethylhexanol 411.45
    isooctanol 236.94
    dipropyl ether 553.76
    1,2-dichlorobenzene 197.37
    ethyl lactate 276.56
    propylene carbonate 1048.76
    n-methylformamide 2980.33
    2-pentanol 1358.27
    n-pentane 31.2
    1-propoxy-2-propanol 1147.9
    1-methoxy-2-propyl acetate 862.26
    2-(2-methoxypropoxy) propanol 376.51
    mesitylene 103.08
    ε-caprolactone 1266.87
    p-cymene 71.3
    epichlorohydrin 3105.5
    1,1,1-trichloroethane 623.78
    2-aminoethanol 1522.3
    morpholine-4-carbaldehyde 1380.54
    sulfolane 2604.37
    2,2,4-trimethylpentane 25.99
    2-methyltetrahydrofuran 3006.13
    n-hexyl acetate 472.55
    isooctane 33.67
    2-(2-butoxyethoxy)ethanol 695.09
    sec-butyl acetate 458.3
    tert-butyl acetate 965.01
    decalin 24.75
    glycerin 849.27
    diglyme 1282.81
    acrylic acid 838.19
    isopropyl myristate 147.79
    n-butyric acid 2195.66
    acetyl acetate 644.49
    di(2-ethylhexyl) phthalate 119.68
    ethyl propionate 714.07
    nitromethane 3149.42
    1,2-diethoxyethane 869.89
    benzonitrile 402.51
    trioctyl phosphate 112.62
    1-bromopropane 424.37
    gamma-valerolactone 2606.7
    n-decanol 162.59
    triethyl phosphate 127.54
    4-methyl-2-pentanol 505.91
    propionitrile 1731.26
    vinylene carbonate 684.26
    1,1,2-trichlorotrifluoroethane 967.11
    DMS 328.74
    cumene 72.66
    2-octanol 189.96
    2-hexanone 1046.46
    octyl acetate 200.52
    limonene 133.52
    1,2-dimethoxyethane 2164.41
    ethyl orthosilicate 127.15
    tributyl phosphate 138.13
    diacetone alcohol 1215.87
    N,N-dimethylaniline 182.53
    acrylonitrile 1615.13
    aniline 483.26
    1,3-propanediol 2069.92
    bromobenzene 222.02
    dibromomethane 423.44
    1,1,2,2-tetrachloroethane 956.78
    2-methyl-cyclohexyl acetate 261.68
    tetrabutyl urea 168.71
    diisobutyl methanol 205.06
    2-phenylethanol 386.67
    styrene 121.27
    dioctyl adipate 198.7
    dimethyl sulfate 606.85
    ethyl butyrate 528.89
    methyl lactate 586.89
    butyl lactate 263.46
    diethyl carbonate 256.58
    propanediol butyl ether 558.68
    triethyl orthoformate 242.39
    p-tert-butyltoluene 78.46
    methyl 4-tert-butylbenzoate 244.14
    morpholine 3783.05
    tert-butylamine 1562.0
    n-dodecanol 120.75
    dimethoxymethane 2633.32
    ethylene carbonate 705.81
    cyrene 310.69
    2-ethoxyethyl acetate 467.77
    2-ethylhexyl acetate 488.39
    1,2,4-trichlorobenzene 251.21
    4-methylpyridine 947.05
    dibutyl ether 332.91
    2,6-dimethyl-4-heptanol 205.06
    DEF 1729.34
    dimethyl isosorbide 574.26
    tetrachloroethylene 508.18
    eugenol 262.07
    triacetin 299.97
    span 80 338.09
    1,4-butanediol 499.77
    1,1-dichloroethane 929.41
    2-methyl-1-pentanol 716.72
    methyl formate 1588.85
    2-methyl-1-butanol 1326.57
    n-decane 18.2
    butyronitrile 1846.85
    3,7-dimethyl-1-octanol 259.58
    1-chlorooctane 115.18
    1-chlorotetradecane 40.57
    n-nonane 17.36
    undecane 14.29
    tert-butylcyclohexane 32.03
    cyclooctane 13.74
    cyclopentanol 1647.38
    tetrahydropyran 2665.9
    tert-amyl methyl ether 847.14
    2,5,8-trioxanonane 697.04
    1-hexene 279.99
    2-isopropoxyethanol 799.9
    2,2,2-trifluoroethanol 255.74
    methyl butyrate 1073.5

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction