4-(4-Aminophenyl)butanamide

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  • Identifiers

    CAS number
    69024-58-4

    Molecular formula
    C10H14N2O

    SMILES
    C1=CC(=CC=C1CCCC(=O)N)N

    Safety labels

  • Odor profile

    Fragrance
    Meaty 33.26%
    Sweet 31.58%
    Grape 31.35%
    Animal 31.14%
    Citrus 29.43%
    Cheesy 29.0%
    Floral 27.34%
    Savory 27.17%
    Fishy 25.47%
    Odorless 25.33%

     

    Flavor
    Mild 38.65%
    Fruity 28.19%
    Sweet 27.78%
    Floral 26.54%
    Odorless 26.15%
    Meaty 22.7%
    Fatty 21.5%
    Honeysuckle 21.32%
    Orange flower 20.35%
    Oily 20.08%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.7

    pKa est.
    5.31 (weak acid)

    Molecular weight
    178.23 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    381°C

    Flash point

    • 191.79 ˚C est.

  • Synonyms

    • 4-(4-aminophenyl)butanamide
    • 69024-58-4
    • SCHEMBL547175
    • DA-03573
    • 69024-58-4

  • Applications

    4-(4-Aminophenyl)butanamide (CAS 69024-58-4) is primarily used as an organic synthesis intermediate in pharmaceutical and specialty chemical applications. It serves as a building block for the preparation of pharmaceutical intermediates and fine chemicals, and is used in polymer and materials chemistry as a precursor for specialty polymers or as a functional arylamine unit. In dye and pigment chemistry, it can act as a scaffold for arylamine derivatives, enabling further functionalization for coatings and related materials.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 32.31
    methanol 175.72
    isopropanol 7.84
    water 75.17
    ethyl acetate 7.91
    n-propanol 13.78
    acetone 20.85
    n-butanol 7.78
    acetonitrile 7.13
    DMF 123.21
    toluene 0.94
    isobutanol 6.77
    1,4-dioxane 8.77
    methyl acetate 8.12
    THF 33.84
    2-butanone 9.42
    n-pentanol 7.14
    sec-butanol 4.72
    n-hexane 0.18
    ethylene glycol 100.22
    NMP 111.16
    cyclohexane 0.1
    DMSO 241.43
    n-butyl acetate 8.3
    n-octanol 1.64
    chloroform 2.4
    n-propyl acetate 7.54
    acetic acid 190.73
    dichloromethane 1.67
    cyclohexanone 19.12
    propylene glycol 75.98
    isopropyl acetate 6.13
    DMAc 187.78
    2-ethoxyethanol 77.96
    isopentanol 8.14
    n-heptane 0.18
    ethyl formate 17.74
    1,2-dichloroethane 1.54
    n-hexanol 8.34
    2-methoxyethanol 150.81
    isobutyl acetate 4.95
    tetrachloromethane 1.16
    n-pentyl acetate 3.79
    transcutol 129.67
    n-heptanol 4.24
    ethylbenzene 0.64
    MIBK 7.16
    2-propoxyethanol 54.33
    tert-butanol 12.32
    MTBE 3.35
    2-butoxyethanol 22.75
    propionic acid 55.95
    o-xylene 1.36
    formic acid 404.59
    diethyl ether 1.6
    m-xylene 1.35
    p-xylene 1.11
    chlorobenzene 1.69
    dimethyl carbonate 15.97
    n-octane 0.08
    formamide 388.33
    cyclopentanone 49.4
    2-pentanone 7.08
    anisole 4.68
    cyclopentyl methyl ether 7.9
    gamma-butyrolactone 77.58
    1-methoxy-2-propanol 60.93
    pyridine 8.5
    3-pentanone 5.54
    furfural 86.22
    n-dodecane 0.06
    diethylene glycol 106.18
    diisopropyl ether 0.89
    tert-amyl alcohol 8.51
    acetylacetone 25.55
    n-hexadecane 0.06
    acetophenone 9.3
    methyl propionate 12.62
    isopentyl acetate 8.28
    trichloroethylene 5.16
    n-nonanol 1.77
    cyclohexanol 4.6
    benzyl alcohol 10.81
    2-ethylhexanol 3.76
    isooctanol 3.33
    dipropyl ether 2.99
    1,2-dichlorobenzene 2.41
    ethyl lactate 17.04
    propylene carbonate 38.39
    n-methylformamide 123.62
    2-pentanol 2.98
    n-pentane 0.09
    1-propoxy-2-propanol 25.13
    1-methoxy-2-propyl acetate 21.95
    2-(2-methoxypropoxy) propanol 27.94
    mesitylene 0.97
    ε-caprolactone 22.18
    p-cymene 1.16
    epichlorohydrin 25.29
    1,1,1-trichloroethane 1.79
    2-aminoethanol 108.22
    morpholine-4-carbaldehyde 97.31
    sulfolane 117.84
    2,2,4-trimethylpentane 0.14
    2-methyltetrahydrofuran 9.97
    n-hexyl acetate 4.12
    isooctane 0.11
    2-(2-butoxyethoxy)ethanol 35.1
    sec-butyl acetate 4.07
    tert-butyl acetate 9.06
    decalin 0.15
    glycerin 203.31
    diglyme 67.68
    acrylic acid 78.17
    isopropyl myristate 1.54
    n-butyric acid 46.87
    acetyl acetate 12.73
    di(2-ethylhexyl) phthalate 6.62
    ethyl propionate 6.62
    nitromethane 219.71
    1,2-diethoxyethane 8.01
    benzonitrile 6.35
    trioctyl phosphate 3.3
    1-bromopropane 0.49
    gamma-valerolactone 98.62
    n-decanol 1.31
    triethyl phosphate 6.88
    4-methyl-2-pentanol 3.27
    propionitrile 4.59
    vinylene carbonate 30.01
    1,1,2-trichlorotrifluoroethane 82.55
    DMS 9.24
    cumene 0.82
    2-octanol 1.45
    2-hexanone 6.38
    octyl acetate 2.48
    limonene 1.37
    1,2-dimethoxyethane 49.49
    ethyl orthosilicate 6.13
    tributyl phosphate 4.4
    diacetone alcohol 29.74
    N,N-dimethylaniline 4.21
    acrylonitrile 11.24
    aniline 6.09
    1,3-propanediol 77.6
    bromobenzene 1.01
    dibromomethane 0.87
    1,1,2,2-tetrachloroethane 4.68
    2-methyl-cyclohexyl acetate 8.25
    tetrabutyl urea 6.3
    diisobutyl methanol 2.18
    2-phenylethanol 10.45
    styrene 0.7
    dioctyl adipate 4.63
    dimethyl sulfate 44.91
    ethyl butyrate 7.4
    methyl lactate 41.46
    butyl lactate 11.13
    diethyl carbonate 6.6
    propanediol butyl ether 25.17
    triethyl orthoformate 7.45
    p-tert-butyltoluene 1.08
    methyl 4-tert-butylbenzoate 14.62
    morpholine 16.5
    tert-butylamine 3.21
    n-dodecanol 0.94
    dimethoxymethane 32.5
    ethylene carbonate 23.39
    cyrene 36.95
    2-ethoxyethyl acetate 10.71
    2-ethylhexyl acetate 5.39
    1,2,4-trichlorobenzene 3.86
    4-methylpyridine 6.57
    dibutyl ether 1.07
    2,6-dimethyl-4-heptanol 2.18
    DEF 17.79
    dimethyl isosorbide 43.45
    tetrachloroethylene 5.14
    eugenol 19.84
    triacetin 13.88
    span 80 18.2
    1,4-butanediol 38.2
    1,1-dichloroethane 0.99
    2-methyl-1-pentanol 7.53
    methyl formate 69.55
    2-methyl-1-butanol 7.0
    n-decane 0.09
    butyronitrile 4.09
    3,7-dimethyl-1-octanol 2.14
    1-chlorooctane 0.35
    1-chlorotetradecane 0.17
    n-nonane 0.07
    undecane 0.07
    tert-butylcyclohexane 0.17
    cyclooctane 0.06
    cyclopentanol 9.96
    tetrahydropyran 3.15
    tert-amyl methyl ether 3.27
    2,5,8-trioxanonane 50.61
    1-hexene 0.61
    2-isopropoxyethanol 32.53
    2,2,2-trifluoroethanol 87.63
    methyl butyrate 10.68

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction