4-(2,2,3,3-Tetramethylbutyl)phenol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    54932-78-4

    Molecular formula
    C14H22O

    SMILES
    CC(C)(C)C(C)(C)CC1=CC=C(C=C1)O

    Safety labels

  • Odor profile

    Fragrance
    Phenolic 58.8%
    Woody 51.11%
    Spicy 48.75%
    Leathery 48.1%
    Dry 39.1%
    Medicinal 38.14%
    Animal 33.85%
    Smoky 32.51%
    Camphoreous 28.07%
    Vetiver 27.46%

     

    Flavor
    Camphor 34.96%
    Woody 34.71%
    Phenolic 34.28%
    Musty 24.77%
    Leather 24.58%
    Medicinal 24.0%
    Mild 23.44%
    Spice 23.32%
    Creosote 21.51%
    Guaiacol 20.62%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.7

    pKa est.
    9.16 (weak base)

    Molecular weight
    206.32 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    293°C

    Flash point

    • 122.81 ˚C est.

  • Synonyms

    • Phenol, 4-(2,2,3,3-tetramethylbutyl)-
    • 4-(2,2,3,3-tetramethylbutyl)phenol
    • 54932-78-4
    • DTXSID1068982
    • RefChem:1069742
    • DTXCID5041807
    • SCHEMBL8191949
    • 4-(2,2,3,3-tetramethylbutyl) phenol
    • DB-357327
    • 4-(2,2,3,3-TETRAMETHYL BUTYL) PHENOL
    • 54932-78-4

  • Applications

    For 4-(2,2,3,3-Tetramethylbutyl)phenol (CAS 54932-78-4), this hindered phenol is primarily used as an antioxidant and thermal stabilizer for polymers and rubbers, protecting plastics and elastomers from oxidative degradation during processing; it also serves as an antioxidant additive in lubricants and industrial fluids; in coatings and inks, it acts as a stabilizer to improve color stability and aging resistance; in adhesive formulations and polymer composites, it contributes to improved oxidative stability and shelf life; it may be used as an intermediate in the synthesis of specialty antioxidants for industrial applications; subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1043.85
    methanol 631.33
    isopropanol 964.11
    water 1.23
    ethyl acetate 2023.47
    n-propanol 1046.62
    acetone 1585.78
    n-butanol 877.71
    acetonitrile 1384.88
    DMF 1653.39
    toluene 589.04
    isobutanol 706.63
    1,4-dioxane 1744.44
    methyl acetate 2028.69
    THF 2788.21
    2-butanone 2079.68
    n-pentanol 558.67
    sec-butanol 1005.66
    n-hexane 279.75
    ethylene glycol 171.7
    NMP 891.73
    cyclohexane 198.67
    DMSO 914.16
    n-butyl acetate 1159.7
    n-octanol 394.19
    chloroform 1835.37
    n-propyl acetate 976.93
    acetic acid 444.05
    dichloromethane 1253.82
    cyclohexanone 1212.71
    propylene glycol 468.31
    isopropyl acetate 1193.88
    DMAc 1762.8
    2-ethoxyethanol 864.94
    isopentanol 721.54
    n-heptane 166.81
    ethyl formate 788.79
    1,2-dichloroethane 1005.76
    n-hexanol 933.39
    2-methoxyethanol 1301.76
    isobutyl acetate 630.2
    tetrachloromethane 411.49
    n-pentyl acetate 519.36
    transcutol 2099.02
    n-heptanol 433.71
    ethylbenzene 458.7
    MIBK 846.35
    2-propoxyethanol 1455.61
    tert-butanol 1530.09
    MTBE 2298.67
    2-butoxyethanol 714.75
    propionic acid 813.83
    o-xylene 404.93
    formic acid 169.41
    diethyl ether 1681.19
    m-xylene 485.19
    p-xylene 595.94
    chlorobenzene 625.37
    dimethyl carbonate 683.18
    n-octane 81.21
    formamide 555.33
    cyclopentanone 1841.01
    2-pentanone 1495.06
    anisole 1012.41
    cyclopentyl methyl ether 1237.83
    gamma-butyrolactone 1886.09
    1-methoxy-2-propanol 1441.5
    pyridine 1111.93
    3-pentanone 1301.22
    furfural 1103.77
    n-dodecane 47.76
    diethylene glycol 743.17
    diisopropyl ether 648.8
    tert-amyl alcohol 1305.49
    acetylacetone 1301.18
    n-hexadecane 53.74
    acetophenone 700.67
    methyl propionate 1529.88
    isopentyl acetate 1057.78
    trichloroethylene 1816.71
    n-nonanol 363.95
    cyclohexanol 530.93
    benzyl alcohol 469.21
    2-ethylhexanol 584.81
    isooctanol 367.54
    dipropyl ether 910.47
    1,2-dichlorobenzene 586.45
    ethyl lactate 491.81
    propylene carbonate 1082.94
    n-methylformamide 1090.38
    2-pentanol 759.26
    n-pentane 198.07
    1-propoxy-2-propanol 1172.57
    1-methoxy-2-propyl acetate 1334.44
    2-(2-methoxypropoxy) propanol 694.95
    mesitylene 344.1
    ε-caprolactone 1108.37
    p-cymene 277.56
    epichlorohydrin 1795.14
    1,1,1-trichloroethane 1508.79
    2-aminoethanol 538.08
    morpholine-4-carbaldehyde 1271.99
    sulfolane 1362.55
    2,2,4-trimethylpentane 142.86
    2-methyltetrahydrofuran 1977.88
    n-hexyl acetate 770.14
    isooctane 132.01
    2-(2-butoxyethoxy)ethanol 854.06
    sec-butyl acetate 792.2
    tert-butyl acetate 1448.93
    decalin 159.72
    glycerin 418.79
    diglyme 1506.54
    acrylic acid 534.88
    isopropyl myristate 358.51
    n-butyric acid 957.86
    acetyl acetate 905.45
    di(2-ethylhexyl) phthalate 239.9
    ethyl propionate 1091.17
    nitromethane 1403.98
    1,2-diethoxyethane 1042.98
    benzonitrile 520.93
    trioctyl phosphate 208.79
    1-bromopropane 841.97
    gamma-valerolactone 1831.12
    n-decanol 290.66
    triethyl phosphate 388.71
    4-methyl-2-pentanol 521.54
    propionitrile 1326.58
    vinylene carbonate 814.29
    1,1,2-trichlorotrifluoroethane 1072.83
    DMS 726.54
    cumene 340.5
    2-octanol 302.84
    2-hexanone 988.93
    octyl acetate 419.24
    limonene 392.92
    1,2-dimethoxyethane 1496.1
    ethyl orthosilicate 400.04
    tributyl phosphate 270.09
    diacetone alcohol 1179.82
    N,N-dimethylaniline 683.42
    acrylonitrile 1292.33
    aniline 667.67
    1,3-propanediol 629.75
    bromobenzene 669.67
    dibromomethane 940.66
    1,1,2,2-tetrachloroethane 1616.79
    2-methyl-cyclohexyl acetate 610.08
    tetrabutyl urea 291.5
    diisobutyl methanol 369.82
    2-phenylethanol 653.15
    styrene 494.4
    dioctyl adipate 400.26
    dimethyl sulfate 844.32
    ethyl butyrate 865.82
    methyl lactate 660.25
    butyl lactate 449.42
    diethyl carbonate 604.01
    propanediol butyl ether 557.57
    triethyl orthoformate 594.98
    p-tert-butyltoluene 324.98
    methyl 4-tert-butylbenzoate 644.52
    morpholine 1987.0
    tert-butylamine 1093.04
    n-dodecanol 227.68
    dimethoxymethane 1437.71
    ethylene carbonate 773.8
    cyrene 552.51
    2-ethoxyethyl acetate 747.84
    2-ethylhexyl acetate 794.1
    1,2,4-trichlorobenzene 672.25
    4-methylpyridine 1096.98
    dibutyl ether 606.36
    2,6-dimethyl-4-heptanol 369.82
    DEF 1144.86
    dimethyl isosorbide 1143.72
    tetrachloroethylene 917.73
    eugenol 545.39
    triacetin 686.74
    span 80 564.51
    1,4-butanediol 256.82
    1,1-dichloroethane 1448.92
    2-methyl-1-pentanol 521.22
    methyl formate 730.17
    2-methyl-1-butanol 696.44
    n-decane 87.86
    butyronitrile 1105.87
    3,7-dimethyl-1-octanol 446.51
    1-chlorooctane 317.19
    1-chlorotetradecane 127.13
    n-nonane 88.4
    undecane 62.59
    tert-butylcyclohexane 205.43
    cyclooctane 105.43
    cyclopentanol 664.54
    tetrahydropyran 1756.45
    tert-amyl methyl ether 1408.93
    2,5,8-trioxanonane 951.1
    1-hexene 696.05
    2-isopropoxyethanol 724.21
    2,2,2-trifluoroethanol 281.59
    methyl butyrate 1157.61

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction