3,5-Dimethylpyridine

Overview IFRA Request a quote

  • Identifiers

    CAS number
    591-22-0

    Molecular formula
    C7H9N

    SMILES
    CC1=CC(=CN=C1)C

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Green 80.5%
    Earthy 53.06%
    Fatty 48.42%
    Nutty 42.64%
    Roasted 37.76%
    Woody 37.53%
    Animal 37.22%
    Musty 32.28%
    Leafy 31.36%
    Tobacco 30.8%

     

    Flavor
    Woody 46.53%
    Leather 34.28%
    Nutty 34.03%
    Musty 30.77%
    Earthy 29.32%
    Tobacco 28.24%
    Phenolic 25.33%
    Plastic 25.31%
    Coffee 24.47%
    Smoky 24.37%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.8

    pKa est.
    5.43 (weak acid)

    Molecular weight
    107.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point est.
    170°C

    Flash point

    • 38.79 ˚C est.

  • Synonyms

    • 3,5-DIMETHYLPYRIDINE
    • 3,5-Lutidine
    • 591-22-0
    • Pyridine, 3,5-dimethyl-
    • UNII-6Q4YPZ045V
    • 6Q4YPZ045V
    • DTXSID5052254
    • 3,5-dimethyl-pyridine
    • EINECS 209-708-6
    • MFCD00006404
    • NSC 60736
    • NSC-60736
    • DTXCID0030825
    • EC 209-708-6
    • 3,5-Dimethylpyridine; NSC 60736
    • 3,5-Lutdcine
    • 3,5lutidine
    • 3,5 lutidine
    • NSC60736
    • Pyridine, 3,5dimethyl
    • NCIOpen2_004681
    • SCHEMBL24225
    • 3,5-Lutidine, >=98%
    • 3,5-Lutidine, analytical standard
    • BCP26361
    • Tox21_303943
    • STL280373
    • AKOS015891741
    • FL33458
    • NCGC00357179-01
    • AC-15531
    • CAS-591-22-0
    • DB-024152
    • L0068
    • NS00006031
    • EN300-82871
    • A832172
    • Q23636070
    • F0001-1549
    • 209-708-6

  • Applications

    3,5-Dimethylpyridine (CAS 591-22-0) is primarily used as a chemical intermediate and building block in synthetic chemistry. It serves as a precursor in the manufacture of agrochemicals, including pesticide and herbicide components, and in the preparation of pharmaceutical lead compounds and related intermediates. It is also employed as a starting material for the synthesis of dyes and pigments, where the pyridine ring is incorporated into colorant molecules. In catalysis and materials science, 3,5-dimethylpyridine can function as a ligand or co-ligand in metal-catalyzed processes and may be used as a building block for pyridine-containing polymers and specialty materials. Depending on formulation and regulatory constraints, it may be used in other customized chemical syntheses as an intermediate, subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1265.81
    methanol 1740.34
    isopropanol 603.84
    water 10.06
    ethyl acetate 747.74
    n-propanol 778.5
    acetone 899.51
    n-butanol 835.08
    acetonitrile 766.5
    DMF 569.69
    toluene 392.89
    isobutanol 555.33
    1,4-dioxane 1072.65
    methyl acetate 602.26
    THF 1539.57
    2-butanone 735.64
    n-pentanol 614.75
    sec-butanol 564.51
    n-hexane 360.08
    ethylene glycol 193.17
    NMP 688.85
    cyclohexane 267.93
    DMSO 544.22
    n-butyl acetate 1322.75
    n-octanol 346.96
    chloroform 1514.23
    n-propyl acetate 502.94
    acetic acid 969.88
    dichloromethane 1556.31
    cyclohexanone 904.65
    propylene glycol 197.67
    isopropyl acetate 423.39
    DMAc 411.65
    2-ethoxyethanol 646.69
    isopentanol 680.48
    n-heptane 366.93
    ethyl formate 622.43
    1,2-dichloroethane 821.85
    n-hexanol 1115.55
    2-methoxyethanol 959.84
    isobutyl acetate 348.85
    tetrachloromethane 451.31
    n-pentyl acetate 397.74
    transcutol 1431.32
    n-heptanol 404.65
    ethylbenzene 183.91
    MIBK 428.0
    2-propoxyethanol 1201.9
    tert-butanol 632.93
    MTBE 700.97
    2-butoxyethanol 540.54
    propionic acid 522.8
    o-xylene 219.43
    formic acid 493.87
    diethyl ether 1062.63
    m-xylene 263.52
    p-xylene 230.3
    chlorobenzene 492.23
    dimethyl carbonate 199.22
    n-octane 98.95
    formamide 389.16
    cyclopentanone 882.75
    2-pentanone 752.84
    anisole 351.66
    cyclopentyl methyl ether 820.27
    gamma-butyrolactone 872.65
    1-methoxy-2-propanol 565.06
    pyridine 705.76
    3-pentanone 481.01
    furfural 786.95
    n-dodecane 59.33
    diethylene glycol 604.67
    diisopropyl ether 319.35
    tert-amyl alcohol 569.43
    acetylacetone 492.36
    n-hexadecane 63.99
    acetophenone 279.75
    methyl propionate 466.2
    isopentyl acetate 884.2
    trichloroethylene 1272.47
    n-nonanol 290.63
    cyclohexanol 558.91
    benzyl alcohol 289.45
    2-ethylhexanol 690.29
    isooctanol 294.46
    dipropyl ether 897.37
    1,2-dichlorobenzene 389.09
    ethyl lactate 170.0
    propylene carbonate 590.8
    n-methylformamide 497.2
    2-pentanol 537.31
    n-pentane 305.96
    1-propoxy-2-propanol 889.49
    1-methoxy-2-propyl acetate 621.27
    2-(2-methoxypropoxy) propanol 342.77
    mesitylene 171.95
    ε-caprolactone 749.28
    p-cymene 221.53
    epichlorohydrin 1056.66
    1,1,1-trichloroethane 861.25
    2-aminoethanol 373.63
    morpholine-4-carbaldehyde 749.97
    sulfolane 764.75
    2,2,4-trimethylpentane 130.12
    2-methyltetrahydrofuran 1220.73
    n-hexyl acetate 514.8
    isooctane 107.52
    2-(2-butoxyethoxy)ethanol 517.09
    sec-butyl acetate 318.19
    tert-butyl acetate 448.75
    decalin 119.71
    glycerin 233.67
    diglyme 823.8
    acrylic acid 429.53
    isopropyl myristate 196.3
    n-butyric acid 817.67
    acetyl acetate 389.84
    di(2-ethylhexyl) phthalate 173.69
    ethyl propionate 356.13
    nitromethane 904.21
    1,2-diethoxyethane 889.85
    benzonitrile 421.94
    trioctyl phosphate 146.09
    1-bromopropane 766.76
    gamma-valerolactone 1034.36
    n-decanol 216.46
    triethyl phosphate 194.15
    4-methyl-2-pentanol 316.0
    propionitrile 553.44
    vinylene carbonate 549.52
    1,1,2-trichlorotrifluoroethane 555.56
    DMS 281.15
    cumene 147.29
    2-octanol 233.05
    2-hexanone 547.7
    octyl acetate 264.49
    limonene 382.18
    1,2-dimethoxyethane 927.23
    ethyl orthosilicate 218.1
    tributyl phosphate 191.75
    diacetone alcohol 431.12
    N,N-dimethylaniline 222.39
    acrylonitrile 504.74
    aniline 410.66
    1,3-propanediol 559.05
    bromobenzene 505.34
    dibromomethane 1131.73
    1,1,2,2-tetrachloroethane 886.36
    2-methyl-cyclohexyl acetate 368.87
    tetrabutyl urea 201.55
    diisobutyl methanol 323.67
    2-phenylethanol 446.33
    styrene 239.23
    dioctyl adipate 225.22
    dimethyl sulfate 215.17
    ethyl butyrate 621.07
    methyl lactate 187.54
    butyl lactate 240.04
    diethyl carbonate 317.63
    propanediol butyl ether 323.2
    triethyl orthoformate 379.23
    p-tert-butyltoluene 210.48
    methyl 4-tert-butylbenzoate 253.7
    morpholine 1078.04
    tert-butylamine 514.09
    n-dodecanol 169.82
    dimethoxymethane 610.9
    ethylene carbonate 494.36
    cyrene 251.89
    2-ethoxyethyl acetate 466.66
    2-ethylhexyl acetate 721.41
    1,2,4-trichlorobenzene 421.16
    4-methylpyridine 732.39
    dibutyl ether 532.03
    2,6-dimethyl-4-heptanol 323.67
    DEF 650.03
    dimethyl isosorbide 511.15
    tetrachloroethylene 724.67
    eugenol 264.24
    triacetin 281.78
    span 80 311.99
    1,4-butanediol 259.9
    1,1-dichloroethane 888.68
    2-methyl-1-pentanol 548.86
    methyl formate 443.86
    2-methyl-1-butanol 630.35
    n-decane 105.17
    butyronitrile 841.07
    3,7-dimethyl-1-octanol 356.85
    1-chlorooctane 287.11
    1-chlorotetradecane 113.71
    n-nonane 116.25
    undecane 74.13
    tert-butylcyclohexane 136.71
    cyclooctane 119.91
    cyclopentanol 562.24
    tetrahydropyran 1139.29
    tert-amyl methyl ether 579.07
    2,5,8-trioxanonane 497.38
    1-hexene 638.48
    2-isopropoxyethanol 436.97
    2,2,2-trifluoroethanol 295.01
    methyl butyrate 502.11

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction