3,4-Dimethoxybenzyl alcohol

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  • Identifiers

    CAS number
    93-03-8

    Molecular formula
    C9H12O3

    SMILES
    COC1=C(C=C(C=C1)CO)OC

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Vanilla 80.7%
    Sweet 72.25%
    Balsamic 49.21%
    Creamy 47.33%
    Phenolic 46.38%
    Floral 45.86%
    Fruity 43.97%
    Powdery 43.15%
    Aromatic 41.2%
    Anisic 38.59%

     

    Flavor
    Sweet 80.24%
    Vanilla 67.36%
    Powdery 52.19%
    Woody 48.12%
    Creamy 46.96%
    Bitter 45.99%
    Phenolic 44.84%
    Smoky 43.72%
    Flower 40.46%
    Caramel 40.16%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    0.6

    pKa est.
    7.72 (neutral)

    Molecular weight
    168.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    300°C

    Flash point

    • 122.52 ˚C est.

  • Synonyms

    • 3,4-Dimethoxybenzyl alcohol
    • 93-03-8
    • (3,4-Dimethoxyphenyl)methanol
    • VERATRYL ALCOHOL
    • Benzenemethanol, 3,4-dimethoxy-
    • 3,4-Dimethoxyphenylmethyl alcohol
    • veratrole alcohol
    • MFCD00004638
    • 3,4-dimethoxybenzenemethanol
    • dimethoxybenzyl alcohol
    • UNII-MB4T4A711H
    • VERATRALCOHOL
    • NSC 6317
    • NSC-6317
    • EINECS 202-212-0
    • 3,4-dimethoxy-benzyl alcohol
    • AI3-24181
    • MB4T4A711H
    • DTXSID1059076
    • CHEBI:62150
    • VERAPAMIL HYDROCHLORIDE IMPURITY E [EP IMPURITY]
    • VERAPAMIL HYDROCHLORIDE IMPURITY E (EP IMPURITY)
    • 3,4-dimethoxybenzyl methanol
    • VOH
    • Veratryl alcohol (8CI)
    • 3,4dimethoxybenzyl alcohol
    • bmse010029
    • 3,4-Dimethoxybenzyl alcohol (Veratryl alcohol)
    • Benzenemethanol,4-dimethoxy-
    • Benzenemethanol, 3,4dimethoxy
    • SCHEMBL119395
    • VERATRYL ALCOHOL [INCI]
    • (3,4-dimethoxyphenyl)-methanol
    • 3,4Dimethoxyphenylmethyl alcohol
    • DTXCID2048826
    • NSC6317
    • (3,4-Dimethoxyphenyl)methanol #
    • [3,4-bis(methyloxy)phenyl]methanol
    • 3,4-Dimethoxybenzyl alcohol, 96%
    • BBL027469
    • s3213
    • STL373549
    • DIMETHOXYBENZYL ALCOHOL [INCI]
    • AKOS000119346
    • FD10790
    • SY001541
    • DB-057359
    • HY-107858
    • CS-0030741
    • NS00039520
    • V0020
    • EN300-20192
    • C21420
    • (3,4-Dimethoxyphenyl)methanol, Veratryl alcohol
    • Q410698
    • Q27160083
    • F0001-2235
    • Z104477212

  • Applications

    3,4-Dimethoxybenzyl alcohol is primarily used as an organic synthesis intermediate for the preparation of 3,4-dimethoxybenzaldehyde and related 3,4-dimethoxyphenyl derivatives, which feed fragrance and flavor chemistry. It is commonly evaluated as a building block in perfumery and cosmetics for generating aroma compounds, and can serve as a precursor in the manufacture of fragrance ingredients. In industrial manufacturing, it also serves as a chemical building block for specialty polymers and coatings, where it can be incorporated into intermediates for functionalized monomers or UV-curable systems. It may be used as a pharmaceutical intermediate in synthetic sequences, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 246.94
    methanol 312.0
    isopropanol 151.44
    water 5.79
    ethyl acetate 255.8
    n-propanol 175.75
    acetone 440.51
    n-butanol 113.29
    acetonitrile 492.27
    DMF 621.19
    toluene 36.67
    isobutanol 100.19
    1,4-dioxane 586.6
    methyl acetate 352.17
    THF 533.73
    2-butanone 238.66
    n-pentanol 86.18
    sec-butanol 117.36
    n-hexane 6.98
    ethylene glycol 283.8
    NMP 367.9
    cyclohexane 27.19
    DMSO 1377.23
    n-butyl acetate 149.73
    n-octanol 57.91
    chloroform 636.35
    n-propyl acetate 197.71
    acetic acid 603.42
    dichloromethane 986.05
    cyclohexanone 341.54
    propylene glycol 137.7
    isopropyl acetate 109.73
    DMAc 297.79
    2-ethoxyethanol 357.9
    isopentanol 81.58
    n-heptane 14.34
    ethyl formate 341.67
    1,2-dichloroethane 634.19
    n-hexanol 85.71
    2-methoxyethanol 556.4
    isobutyl acetate 85.29
    tetrachloromethane 132.61
    n-pentyl acetate 90.87
    transcutol 383.01
    n-heptanol 55.54
    ethylbenzene 40.49
    MIBK 82.65
    2-propoxyethanol 204.97
    tert-butanol 232.73
    MTBE 127.29
    2-butoxyethanol 127.99
    propionic acid 300.0
    o-xylene 47.75
    formic acid 347.6
    diethyl ether 156.73
    m-xylene 37.68
    p-xylene 53.49
    chlorobenzene 127.98
    dimethyl carbonate 146.33
    n-octane 7.45
    formamide 676.24
    cyclopentanone 479.8
    2-pentanone 149.3
    anisole 141.52
    cyclopentyl methyl ether 162.74
    gamma-butyrolactone 757.26
    1-methoxy-2-propanol 252.96
    pyridine 288.68
    3-pentanone 123.59
    furfural 554.16
    n-dodecane 6.45
    diethylene glycol 266.59
    diisopropyl ether 36.91
    tert-amyl alcohol 151.02
    acetylacetone 241.19
    n-hexadecane 7.42
    acetophenone 150.88
    methyl propionate 208.91
    isopentyl acetate 105.84
    trichloroethylene 894.69
    n-nonanol 50.34
    cyclohexanol 130.64
    benzyl alcohol 123.91
    2-ethylhexanol 59.94
    isooctanol 47.83
    dipropyl ether 79.6
    1,2-dichlorobenzene 162.76
    ethyl lactate 119.4
    propylene carbonate 352.83
    n-methylformamide 555.52
    2-pentanol 65.09
    n-pentane 8.33
    1-propoxy-2-propanol 130.33
    1-methoxy-2-propyl acetate 130.5
    2-(2-methoxypropoxy) propanol 106.21
    mesitylene 33.52
    ε-caprolactone 305.0
    p-cymene 40.63
    epichlorohydrin 734.95
    1,1,1-trichloroethane 360.27
    2-aminoethanol 247.31
    morpholine-4-carbaldehyde 450.62
    sulfolane 826.51
    2,2,4-trimethylpentane 8.44
    2-methyltetrahydrofuran 299.13
    n-hexyl acetate 111.52
    isooctane 6.09
    2-(2-butoxyethoxy)ethanol 142.49
    sec-butyl acetate 84.76
    tert-butyl acetate 120.31
    decalin 14.85
    glycerin 263.54
    diglyme 373.18
    acrylic acid 334.84
    isopropyl myristate 44.96
    n-butyric acid 280.21
    acetyl acetate 184.96
    di(2-ethylhexyl) phthalate 46.12
    ethyl propionate 135.18
    nitromethane 1299.79
    1,2-diethoxyethane 134.37
    benzonitrile 174.72
    trioctyl phosphate 40.66
    1-bromopropane 154.2
    gamma-valerolactone 549.17
    n-decanol 38.76
    triethyl phosphate 79.5
    4-methyl-2-pentanol 38.19
    propionitrile 241.3
    vinylene carbonate 354.84
    1,1,2-trichlorotrifluoroethane 526.3
    DMS 131.33
    cumene 35.98
    2-octanol 38.95
    2-hexanone 131.43
    octyl acetate 59.54
    limonene 59.14
    1,2-dimethoxyethane 506.8
    ethyl orthosilicate 68.58
    tributyl phosphate 47.73
    diacetone alcohol 154.09
    N,N-dimethylaniline 93.03
    acrylonitrile 385.02
    aniline 110.44
    1,3-propanediol 274.62
    bromobenzene 123.22
    dibromomethane 536.5
    1,1,2,2-tetrachloroethane 587.59
    2-methyl-cyclohexyl acetate 96.09
    tetrabutyl urea 63.32
    diisobutyl methanol 39.93
    2-phenylethanol 100.93
    styrene 52.25
    dioctyl adipate 76.41
    dimethyl sulfate 269.59
    ethyl butyrate 125.33
    methyl lactate 145.7
    butyl lactate 78.32
    diethyl carbonate 106.92
    propanediol butyl ether 110.25
    triethyl orthoformate 92.54
    p-tert-butyltoluene 38.1
    methyl 4-tert-butylbenzoate 117.38
    morpholine 534.13
    tert-butylamine 102.19
    n-dodecanol 30.52
    dimethoxymethane 328.1
    ethylene carbonate 302.02
    cyrene 158.25
    2-ethoxyethyl acetate 128.76
    2-ethylhexyl acetate 83.36
    1,2,4-trichlorobenzene 183.68
    4-methylpyridine 180.51
    dibutyl ether 62.02
    2,6-dimethyl-4-heptanol 39.93
    DEF 216.19
    dimethyl isosorbide 211.21
    tetrachloroethylene 451.14
    eugenol 111.61
    triacetin 146.08
    span 80 85.47
    1,4-butanediol 128.39
    1,1-dichloroethane 344.22
    2-methyl-1-pentanol 67.87
    methyl formate 571.69
    2-methyl-1-butanol 80.3
    n-decane 10.58
    butyronitrile 189.1
    3,7-dimethyl-1-octanol 48.74
    1-chlorooctane 44.17
    1-chlorotetradecane 18.64
    n-nonane 10.33
    undecane 8.1
    tert-butylcyclohexane 12.11
    cyclooctane 10.11
    cyclopentanol 197.26
    tetrahydropyran 292.91
    tert-amyl methyl ether 86.67
    2,5,8-trioxanonane 217.44
    1-hexene 25.7
    2-isopropoxyethanol 183.49
    2,2,2-trifluoroethanol 295.84
    methyl butyrate 212.69

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction