3'-Sialyllactose

Overview IFRA Request a quote

  • Identifiers

    CAS number
    35890-38-1

    Molecular formula
    C23H39NO19

    SMILES
    CC(=O)N[C@@H]1[C@H](C[C@@](O[C@H]1[C@@H]([C@@H](CO)O)O)(C(=O)O)O[C@H]2[C@H]([C@H](O[C@H]([C@@H]2O)O[C@H]([C@@H](CO)O)[C@@H]([C@H](C=O)O)O)CO)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 76.7%
    Sweet 40.82%
    Savory 25.23%
    Milky 19.03%
    Cooling 18.56%
    Buttery 17.55%
    Alcoholic 17.23%
    Caramellic 16.62%
    Bitter 15.9%
    Clean 14.13%

     

    Flavor
    Odorless 61.33%
    Bitter 42.33%
    Sweet-like 32.57%
    Sweet 31.75%
    Very mild 29.65%
    Bland 28.6%
    Very slight 20.83%
    Mild 20.32%
    Yeast 20.01%
    Cauliflower 19.68%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    -7.5

    pKa est.
    2.1 (strong acid)

    Molecular weight
    633.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point est.
    5098°C

    Flash point

    • 328.32 ˚C est.

  • Synonyms

    • 3'-Sialyllactose
    • 35890-38-1
    • 3'-Monosialyllactose
    • CYLAC 23
    • DTXSID30905216
    • 32-N-Acetyl-alpha-neuraminyllactose
    • 3'-(N-Acetyl-alpha-neuraminosyl)lactose
    • (2S,4S,5R,6R)-2-{[(2R,3S,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-{[(2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl]oxy}oxan-4-yl]oxy}-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
    • (2S,4S,5R,6R)-2-(((2R,3S,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-(((2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl)oxy)oxan-4-yl)oxy)-5-acetamido-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)oxane-2-carboxylic acid
    • RefChem:583830
    • DTXCID701334324
    • N-acetylneuraminyl-2-3-galactopyranosyl-1-4-glucopyranose
    • (2S,4S,5R,6R)-5-acetamido-2-((2R,3S,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-((2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl)oxyoxan-4-yl)oxy-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)oxane-2-carboxylic acid
    • Sialyllactose
    • N-acetylneuraminoyllactose
    • (2S,4S,5R,6R)-5-acetamido-2-[(2R,3S,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl]oxyoxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
    • MFCD00168068
    • 3'-a-Sialyllactose
    • a2,3-Sialyllactose
    • 3'-Sialyl-D-lactose
    • (2>3')-a-Sialyllactose
    • 3J7TAL60G3
    • 32-N-Acetyl-a-neuraminyllactose
    • 3'-N-Acetylneuraminyl-D-lactose
    • 3'-(N-Acetyl-a-neuraminosyl)lactose
    • a-Neu5Ac-(2>3)-b-D-Gal-(1>4)-D-Glc
    • 3'-SL
    • 3'-N-Acetylneuraminyl-D-lactose sodium slt
    • UNII-3J7TAL60G3
    • 3a(2)-Sialyllactose
    • NAN-LACTOSE
    • GM3 Ganglioside sugar
    • NEURAMIN LACTOSE
    • 3 inverted exclamation mark -Sialyllactose
    • (2>3')-alpha-Sialyllactose
    • orb1744763
    • SCHEMBL8673965
    • OIZGSVFYNBZVIK-FHHHURIISA-N
    • .ALPHA.-2,3-SIALYLLACTOSE
    • AKOS015916417
    • 3 inverted exclamation marka-Sialyllactose
    • AS-82746
    • D-Glucose, O-(N-acetyl-.alpha.-neuraminosyl)-(2.fwdarw.3)-O-.beta.-D-galactopyranosyl-(1.fwdarw.4)-
    • SY286917
    • HY-108065
    • CS-0027263
    • NS00124068
    • 32-N-ACETYL-.ALPHA.-NEURAMINYLLACTOSE
    • 3'-(N-ACETYL-.ALPHA.-NEURAMINOSYL)LACTOSE
    • alpha-Neu5Ac-(2>3)-beta-D-Gal-(1>4)-D-Glc
    • Q3482888
    • alpha-Neu5Ac-(2>3)-beta-delta-Gal-(1>4)-delta-Glc
    • N-ACETYL-.ALPHA.-NEURAMINYL-(2 TO 3')-LACTOSE
    • D-Glucose, O-(N-acetyl-a-neuraminosyl)-(2>3)-O-b-D-galactopyranosyl-(1>4)- (9CI)
    • D-Glucose, O-(N-acetyl-alpha-neuraminosyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-
    • (2S,4S,5R,6R)-5-Acetamido-2-(((2R,3S,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-(((2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-4-hydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid
    • (2S,4S,5R,6R)-5-acetamido-2-[(2S,3R,4S,5S,6R)-2-[(1R,2R,3R)-1-[(1R)-1,2-dihydroxyethyl]-2,3-dihydroxy-4-oxo-butoxy]-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydropyran-2-carboxylic acid
    • 5-Acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-beta-D-galactopyranosyl-(1->4)-D-glucose
    • D-GLUCOSE, O-(N-ACETYL-.ALPHA.-NEURAMINOSYL)-(2 TO 3)-O-.BETA.-D-GALACTOPYRANOSYL-(1 TO 4)-
    • D-glucose, O-5-(acetylamino)-3,5-dideoxy-D-glycero-a-D-galacto-2-nonulopyranonosyl-(2>3)-O-b-D-galactopyranosyl-(1>4)-
    • 35890-38-1

  • Applications

    3'-Sialyllactose is a sialylated oligosaccharide increasingly used as a functional ingredient in infant formula to help mimic human milk oligosaccharides and support gut microbiota; it is commonly evaluated as a prebiotic in foods and dietary supplements to modulate the gut microbiome; in cosmetics and personal care, it is explored as a functional ingredient to support skin microbiome and provide formulation benefits; in research and biotechnology, it serves as a substrate and reference compound for enzymatic synthesis and analytical studies of sialylated oligosaccharides; in animal nutrition, it is studied as a prebiotic additive in livestock feeds to promote gut health. Subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 22.46
    methanol 68.46
    isopropanol 5.49
    water 71.2
    ethyl acetate 2.99
    n-propanol 8.33
    acetone 11.88
    n-butanol 4.12
    acetonitrile 3.37
    DMF 148.61
    toluene 0.6
    isobutanol 2.43
    1,4-dioxane 12.39
    methyl acetate 3.97
    THF 16.23
    2-butanone 5.13
    n-pentanol 1.97
    sec-butanol 3.08
    n-hexane 0.08
    ethylene glycol 70.52
    NMP 127.38
    cyclohexane 0.23
    DMSO 279.88
    n-butyl acetate 0.77
    n-octanol 1.09
    chloroform 0.97
    n-propyl acetate 1.03
    acetic acid 90.57
    dichloromethane 1.76
    cyclohexanone 7.25
    propylene glycol 42.67
    isopropyl acetate 1.37
    DMAc 100.64
    2-ethoxyethanol 24.34
    isopentanol 1.55
    n-heptane 0.15
    ethyl formate 5.67
    1,2-dichloroethane 1.6
    n-hexanol 1.15
    2-methoxyethanol 81.67
    isobutyl acetate 0.36
    tetrachloromethane 0.35
    n-pentyl acetate 1.05
    transcutol 20.42
    n-heptanol 1.34
    ethylbenzene 0.21
    MIBK 1.14
    2-propoxyethanol 11.6
    tert-butanol 2.21
    MTBE 0.84
    2-butoxyethanol 8.03
    propionic acid 12.71
    o-xylene 0.49
    formic acid 262.5
    diethyl ether 2.01
    m-xylene 0.32
    p-xylene 0.21
    chlorobenzene 0.3
    dimethyl carbonate 9.92
    n-octane 0.1
    formamide 183.15
    cyclopentanone 13.69
    2-pentanone 3.76
    anisole 0.87
    cyclopentyl methyl ether 3.24
    gamma-butyrolactone 20.84
    1-methoxy-2-propanol 32.5
    pyridine 6.04
    3-pentanone 2.95
    furfural 21.72
    n-dodecane 0.05
    diethylene glycol 29.87
    diisopropyl ether 0.28
    tert-amyl alcohol 1.86
    acetylacetone 7.7
    n-hexadecane 0.05
    acetophenone 1.59
    methyl propionate 6.09
    isopentyl acetate 0.45
    trichloroethylene 2.31
    n-nonanol 1.04
    cyclohexanol 2.83
    benzyl alcohol 2.25
    2-ethylhexanol 0.43
    isooctanol 0.68
    dipropyl ether 1.13
    1,2-dichlorobenzene 0.27
    ethyl lactate 3.55
    propylene carbonate 5.73
    n-methylformamide 66.35
    2-pentanol 1.65
    n-pentane 0.15
    1-propoxy-2-propanol 5.39
    1-methoxy-2-propyl acetate 3.18
    2-(2-methoxypropoxy) propanol 4.98
    mesitylene 0.19
    ε-caprolactone 7.3
    p-cymene 0.16
    epichlorohydrin 9.86
    1,1,1-trichloroethane 0.39
    2-aminoethanol 50.53
    morpholine-4-carbaldehyde 83.98
    sulfolane 65.09
    2,2,4-trimethylpentane 0.04
    2-methyltetrahydrofuran 4.46
    n-hexyl acetate 1.05
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 8.66
    sec-butyl acetate 0.49
    tert-butyl acetate 1.08
    decalin 0.05
    glycerin 128.31
    diglyme 15.69
    acrylic acid 24.46
    isopropyl myristate 0.34
    n-butyric acid 8.39
    acetyl acetate 2.58
    di(2-ethylhexyl) phthalate 0.7
    ethyl propionate 1.2
    nitromethane 65.35
    1,2-diethoxyethane 2.42
    benzonitrile 0.85
    trioctyl phosphate 0.66
    1-bromopropane 0.56
    gamma-valerolactone 48.29
    n-decanol 0.71
    triethyl phosphate 0.74
    4-methyl-2-pentanol 0.55
    propionitrile 1.7
    vinylene carbonate 6.51
    1,1,2-trichlorotrifluoroethane 29.16
    DMS 2.0
    cumene 0.12
    2-octanol 0.66
    2-hexanone 1.16
    octyl acetate 0.76
    limonene 0.31
    1,2-dimethoxyethane 14.66
    ethyl orthosilicate 0.6
    tributyl phosphate 0.53
    diacetone alcohol 5.43
    N,N-dimethylaniline 0.9
    acrylonitrile 3.91
    aniline 2.14
    1,3-propanediol 36.17
    bromobenzene 0.18
    dibromomethane 0.78
    1,1,2,2-tetrachloroethane 2.06
    2-methyl-cyclohexyl acetate 0.57
    tetrabutyl urea 1.44
    diisobutyl methanol 0.23
    2-phenylethanol 1.16
    styrene 0.25
    dioctyl adipate 0.89
    dimethyl sulfate 26.31
    ethyl butyrate 0.86
    methyl lactate 19.53
    butyl lactate 2.55
    diethyl carbonate 0.58
    propanediol butyl ether 10.27
    triethyl orthoformate 0.96
    p-tert-butyltoluene 0.15
    methyl 4-tert-butylbenzoate 2.27
    morpholine 21.1
    tert-butylamine 0.66
    n-dodecanol 0.49
    dimethoxymethane 31.81
    ethylene carbonate 4.28
    cyrene 13.8
    2-ethoxyethyl acetate 2.82
    2-ethylhexyl acetate 0.35
    1,2,4-trichlorobenzene 0.47
    4-methylpyridine 3.02
    dibutyl ether 0.56
    2,6-dimethyl-4-heptanol 0.23
    DEF 11.89
    dimethyl isosorbide 6.7
    tetrachloroethylene 1.99
    eugenol 2.93
    triacetin 2.79
    span 80 5.01
    1,4-butanediol 12.54
    1,1-dichloroethane 0.67
    2-methyl-1-pentanol 0.85
    methyl formate 42.13
    2-methyl-1-butanol 1.85
    n-decane 0.1
    butyronitrile 1.31
    3,7-dimethyl-1-octanol 0.38
    1-chlorooctane 0.26
    1-chlorotetradecane 0.1
    n-nonane 0.1
    undecane 0.07
    tert-butylcyclohexane 0.03
    cyclooctane 0.11
    cyclopentanol 5.2
    tetrahydropyran 4.09
    tert-amyl methyl ether 1.07
    2,5,8-trioxanonane 11.43
    1-hexene 0.22
    2-isopropoxyethanol 6.86
    2,2,2-trifluoroethanol 40.05
    methyl butyrate 1.84

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction