3-Methoxypyridine

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    7295-76-3

    Molecular formula
    C6H7NO

    SMILES
    COC1=CN=CC=C1

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 76.08%
    Nutty 66.63%
    Earthy 52.61%
    Roasted 47.75%
    Burnt 44.66%
    Phenolic 44.62%
    Musty 43.81%
    Smoky 39.86%
    Anisic 39.51%
    Almond 37.93%

     

    Flavor
    Nutty 54.55%
    Sweet 53.1%
    Fruity 44.28%
    Musty 41.28%
    Earthy 40.15%
    Green 37.76%
    Woody 37.19%
    Tobacco 36.12%
    Caramel 32.11%
    Coffee 28.37%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.0

    pKa est.
    4.72 (weak acid)

    Molecular weight
    109.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Boiling point est.
    185°C

    Flash point

    • 58.38 ˚C est.

  • Synonyms

    • 3-METHOXYPYRIDINE
    • 7295-76-3
    • Pyridine, 3-methoxy-
    • beta-Methoxypyridine
    • .beta.-Methoxypyridine
    • MFCD00673022
    • UNII-XV2A2D8595
    • XV2A2D8595
    • EINECS 230-730-7
    • DTXSID60223238
    • 3-methoxy-pyridine
    • 3-methoxypiridine
    • ss--Methoxypyridine
    • 3-Methoxypyridine, 97%
    • SCHEMBL162478
    • SCHEMBL12015258
    • DTXCID60145729
    • BCP32229
    • BBL103282
    • STL557092
    • AKOS015851686
    • AB06864
    • CS-W008119
    • HY-W008119
    • PS-9281
    • AC-33353
    • BP-12699
    • SY024150
    • Pyridine, 3-methoxy-;beta-Methoxypyridine
    • DB-016016
    • M2304
    • NS00037448
    • EN300-67373
    • Q27294012
    • 230-730-7

  • Applications

    3-Methoxypyridine, CAS 7295-76-3, is mainly used as an intermediate and building block in organic synthesis. In pharmaceuticals it often serves as a precursor for pyridine-containing active compounds; in agrochemicals it is explored as a scaffold for pyridine derivatives that are transformed into active ingredients. Additionally, it can function as a ligand or precursor in homogeneous catalysis and as a starting material for the preparation of heterocyclic and metal-complex compounds. It is also employed as a component in materials development, including pyridine-containing polymers, coatings and related electronic or electrochemical applications, and is commonly used in research as a general synthetic intermediate for further chemical elaboration.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 522.5
    methanol 468.71
    isopropanol 420.83
    water 31.49
    ethyl acetate 562.64
    n-propanol 463.34
    acetone 720.41
    n-butanol 342.39
    acetonitrile 937.81
    DMF 897.44
    toluene 226.95
    isobutanol 342.44
    1,4-dioxane 1033.9
    methyl acetate 678.52
    THF 752.58
    2-butanone 552.89
    n-pentanol 211.31
    sec-butanol 390.65
    n-hexane 27.02
    ethylene glycol 264.86
    NMP 692.99
    cyclohexane 60.13
    DMSO 1545.1
    n-butyl acetate 183.74
    n-octanol 75.08
    chloroform 1454.16
    n-propyl acetate 232.84
    acetic acid 1007.8
    dichloromethane 1552.76
    cyclohexanone 564.15
    propylene glycol 242.43
    isopropyl acetate 216.97
    DMAc 668.92
    2-ethoxyethanol 433.65
    isopentanol 236.05
    n-heptane 30.09
    ethyl formate 414.14
    1,2-dichloroethane 884.85
    n-hexanol 155.01
    2-methoxyethanol 751.22
    isobutyl acetate 113.27
    tetrachloromethane 336.24
    n-pentyl acetate 108.8
    transcutol 645.77
    n-heptanol 75.83
    ethylbenzene 69.35
    MIBK 159.95
    2-propoxyethanol 293.28
    tert-butanol 480.04
    MTBE 324.82
    2-butoxyethanol 165.92
    propionic acid 639.22
    o-xylene 141.39
    formic acid 456.47
    diethyl ether 386.63
    m-xylene 128.49
    p-xylene 108.39
    chlorobenzene 330.39
    dimethyl carbonate 169.25
    n-octane 12.37
    formamide 631.0
    cyclopentanone 638.46
    2-pentanone 339.96
    anisole 209.22
    cyclopentyl methyl ether 362.96
    gamma-butyrolactone 855.35
    1-methoxy-2-propanol 421.4
    pyridine 779.87
    3-pentanone 290.39
    furfural 809.67
    n-dodecane 10.66
    diethylene glycol 312.44
    diisopropyl ether 79.39
    tert-amyl alcohol 393.94
    acetylacetone 355.23
    n-hexadecane 11.9
    acetophenone 191.08
    methyl propionate 422.56
    isopentyl acetate 140.81
    trichloroethylene 1482.06
    n-nonanol 67.13
    cyclohexanol 324.39
    benzyl alcohol 178.6
    2-ethylhexanol 93.14
    isooctanol 65.32
    dipropyl ether 132.92
    1,2-dichlorobenzene 266.01
    ethyl lactate 118.05
    propylene carbonate 382.98
    n-methylformamide 695.4
    2-pentanol 216.11
    n-pentane 38.27
    1-propoxy-2-propanol 196.88
    1-methoxy-2-propyl acetate 178.79
    2-(2-methoxypropoxy) propanol 150.23
    mesitylene 73.01
    ε-caprolactone 451.17
    p-cymene 54.87
    epichlorohydrin 948.39
    1,1,1-trichloroethane 831.92
    2-aminoethanol 374.68
    morpholine-4-carbaldehyde 728.08
    sulfolane 901.98
    2,2,4-trimethylpentane 25.95
    2-methyltetrahydrofuran 656.33
    n-hexyl acetate 137.55
    isooctane 16.07
    2-(2-butoxyethoxy)ethanol 209.57
    sec-butyl acetate 123.21
    tert-butyl acetate 181.23
    decalin 26.67
    glycerin 334.65
    diglyme 439.87
    acrylic acid 556.53
    isopropyl myristate 55.17
    n-butyric acid 574.26
    acetyl acetate 302.79
    di(2-ethylhexyl) phthalate 56.8
    ethyl propionate 204.09
    nitromethane 1631.55
    1,2-diethoxyethane 213.78
    benzonitrile 291.96
    trioctyl phosphate 44.06
    1-bromopropane 435.41
    gamma-valerolactone 803.97
    n-decanol 53.18
    triethyl phosphate 81.24
    4-methyl-2-pentanol 93.89
    propionitrile 570.7
    vinylene carbonate 390.82
    1,1,2-trichlorotrifluoroethane 659.73
    DMS 151.5
    cumene 53.63
    2-octanol 55.09
    2-hexanone 193.48
    octyl acetate 76.93
    limonene 84.02
    1,2-dimethoxyethane 586.78
    ethyl orthosilicate 72.97
    tributyl phosphate 56.3
    diacetone alcohol 238.33
    N,N-dimethylaniline 133.32
    acrylonitrile 726.04
    aniline 366.71
    1,3-propanediol 429.94
    bromobenzene 326.31
    dibromomethane 945.77
    1,1,2,2-tetrachloroethane 987.29
    2-methyl-cyclohexyl acetate 96.41
    tetrabutyl urea 72.7
    diisobutyl methanol 60.01
    2-phenylethanol 135.06
    styrene 101.78
    dioctyl adipate 87.44
    dimethyl sulfate 303.04
    ethyl butyrate 156.5
    methyl lactate 206.31
    butyl lactate 94.5
    diethyl carbonate 114.35
    propanediol butyl ether 141.36
    triethyl orthoformate 107.51
    p-tert-butyltoluene 52.39
    methyl 4-tert-butylbenzoate 135.28
    morpholine 1012.1
    tert-butylamine 259.3
    n-dodecanol 43.1
    dimethoxymethane 414.99
    ethylene carbonate 331.14
    cyrene 171.59
    2-ethoxyethyl acetate 168.89
    2-ethylhexyl acetate 107.46
    1,2,4-trichlorobenzene 336.83
    4-methylpyridine 571.1
    dibutyl ether 92.64
    2,6-dimethyl-4-heptanol 60.01
    DEF 479.41
    dimethyl isosorbide 238.47
    tetrachloroethylene 731.17
    eugenol 135.8
    triacetin 153.63
    span 80 121.34
    1,4-butanediol 178.75
    1,1-dichloroethane 892.28
    2-methyl-1-pentanol 161.74
    methyl formate 497.7
    2-methyl-1-butanol 263.76
    n-decane 16.17
    butyronitrile 443.54
    3,7-dimethyl-1-octanol 81.21
    1-chlorooctane 62.72
    1-chlorotetradecane 26.83
    n-nonane 16.33
    undecane 12.74
    tert-butylcyclohexane 24.96
    cyclooctane 20.41
    cyclopentanol 380.12
    tetrahydropyran 639.52
    tert-amyl methyl ether 227.02
    2,5,8-trioxanonane 279.27
    1-hexene 91.94
    2-isopropoxyethanol 243.94
    2,2,2-trifluoroethanol 397.42
    methyl butyrate 272.81

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Cassie absolute 1a extract 8023-82-3 Acacia farnesiana (L.) Willd., fam. Mimosaceae (Leguminosae) 0.5%