3-Methoxy-1-propanol

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  • Identifiers

    CAS number
    1589-49-7

    Molecular formula
    C4H10O2

    SMILES
    COCCCO

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Ethereal 72.79%
    Alcoholic 67.3%
    Fruity 52.38%
    Fermented 50.23%
    Sweet 50.18%
    Solvent 45.12%
    Winey 33.36%
    Pungent 32.5%
    Oily 27.99%
    Rummy 27.98%

     

    Flavor
    Sweet 64.62%
    Alcoholic 61.85%
    Bitter 47.66%
    Alcohol 45.16%
    Fusel 44.53%
    Musty 44.07%
    Ether 37.82%
    Ethereal 36.38%
    Fruit 34.01%
    Pungent 33.72%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    -0.2

    pKa est.
    8.03 (weak base)

    Molecular weight
    90.12 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point est.
    148°C

    Flash point

    • 47.5 ˚C est.

  • Synonyms

    • 3-METHOXY-1-PROPANOL
    • 1589-49-7
    • 1-Propanol, 3-methoxy-
    • 3-methoxypropanol
    • Trimethylene glycol monomethyl ether
    • beta-PGME
    • 1-Methoxy-3-hydroxypropane
    • UNII-OAK281WZ1P
    • OAK281WZ1P
    • Propylene glycol monomethyl ether, beta
    • BRN 1731204
    • 3-(methyloxy)propan-1-ol
    • DTXSID9073129
    • 4-01-00-02494 (Beilstein Handbook Reference)
    • Propylene glycol monomethyl ether, .beta.
    • .BETA.-PROPYLENE GLYCOL MONOMETHYL ETHER
    • RefChem:94556
    • BETA-PROPYLENE GLYCOL MONOMETHYL ETHER
    • DTXCID5035113
    • 605-167-9
    • JDFDHBSESGTDAL-UHFFFAOYSA-N
    • 3-methoxypropan-1-ol
    • MFCD00039550
    • 3-methoxypropanol-1
    • 1,3-Propanediol Monomethyl Ether
    • 3-methoxy-propanol
    • Propanol, methoxy-
    • 3-(methoxy)propanol
    • 3-methoxy-propan-1-ol
    • HOCH2CH2CH2OCH3
    • SCHEMBL4741
    • SCHEMBL4742
    • CH3O(CH2)3OH
    • SCHEMBL49121
    • SCHEMBL1254287
    • SCHEMBL2283306
    • SCHEMBL5551199
    • SCHEMBL5754375
    • SCHEMBL5909532
    • SCHEMBL13088430
    • STR06978
    • AKOS005292551
    • CS-W020636
    • SB67312
    • Methyl ether of propylene glycol(alpha)
    • 3-Methoxy-1-propanol, >=98.0% (GC)
    • DB-000676
    • M1475
    • NS00009270
    • EN300-42678
    • D77912
    • F078666
    • Q27285538
    • Z431517702
    • 1589-49-7

  • Applications

    3-Methoxy-1-propanol (CAS 1589-49-7) is a polar glycol ether used as a solvent and processing aid in a range of industrial formulations. It may be used as a solvent in coatings, inks and adhesives, and can act as a reactive diluent to adjust viscosity in resin systems. It also serves as an intermediate in organic synthesis and may be employed in cleaning formulations. In cosmetics/personal care formulations, it may be used as a solvent under regulatory controls. Its use is subject to local regulations and formulation-specific constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2470.79
    methanol 4219.26
    isopropanol 1629.07
    water 307.68
    ethyl acetate 268.05
    n-propanol 1596.66
    acetone 578.45
    n-butanol 1129.88
    acetonitrile 589.36
    DMF 1542.94
    toluene 44.41
    isobutanol 874.08
    1,4-dioxane 764.76
    methyl acetate 407.71
    THF 762.27
    2-butanone 352.91
    n-pentanol 464.87
    sec-butanol 950.9
    n-hexane 21.57
    ethylene glycol 1740.64
    NMP 749.51
    cyclohexane 47.91
    DMSO 1341.83
    n-butyl acetate 144.16
    n-octanol 124.04
    chloroform 662.42
    n-propyl acetate 134.65
    acetic acid 2717.6
    dichloromethane 564.29
    cyclohexanone 412.75
    propylene glycol 1474.88
    isopropyl acetate 106.22
    DMAc 779.43
    2-ethoxyethanol 807.33
    isopentanol 549.36
    n-heptane 31.66
    ethyl formate 364.89
    1,2-dichloroethane 296.89
    n-hexanol 405.1
    2-methoxyethanol 2035.07
    isobutyl acetate 70.63
    tetrachloromethane 184.84
    n-pentyl acetate 77.94
    transcutol 725.64
    n-heptanol 145.13
    ethylbenzene 21.87
    MIBK 92.49
    2-propoxyethanol 673.91
    tert-butanol 1165.29
    MTBE 265.87
    2-butoxyethanol 306.95
    propionic acid 1268.55
    o-xylene 41.05
    formic acid 2031.01
    diethyl ether 255.68
    m-xylene 37.11
    p-xylene 33.03
    chlorobenzene 104.29
    dimethyl carbonate 91.28
    n-octane 8.23
    formamide 1353.72
    cyclopentanone 505.74
    2-pentanone 213.61
    anisole 88.2
    cyclopentyl methyl ether 243.56
    gamma-butyrolactone 640.71
    1-methoxy-2-propanol 1002.34
    pyridine 377.51
    3-pentanone 143.93
    furfural 587.77
    n-dodecane 6.63
    diethylene glycol 877.09
    diisopropyl ether 39.88
    tert-amyl alcohol 682.78
    acetylacetone 178.13
    n-hexadecane 7.01
    acetophenone 96.98
    methyl propionate 248.55
    isopentyl acetate 100.33
    trichloroethylene 536.83
    n-nonanol 96.89
    cyclohexanol 572.21
    benzyl alcohol 181.56
    2-ethylhexanol 148.29
    isooctanol 96.27
    dipropyl ether 128.43
    1,2-dichlorobenzene 92.35
    ethyl lactate 142.15
    propylene carbonate 286.18
    n-methylformamide 1256.21
    2-pentanol 476.35
    n-pentane 37.72
    1-propoxy-2-propanol 427.38
    1-methoxy-2-propyl acetate 147.27
    2-(2-methoxypropoxy) propanol 181.84
    mesitylene 24.37
    ε-caprolactone 334.6
    p-cymene 31.15
    epichlorohydrin 498.58
    1,1,1-trichloroethane 256.98
    2-aminoethanol 2124.45
    morpholine-4-carbaldehyde 811.11
    sulfolane 632.19
    2,2,4-trimethylpentane 18.46
    2-methyltetrahydrofuran 477.1
    n-hexyl acetate 106.48
    isooctane 10.73
    2-(2-butoxyethoxy)ethanol 264.07
    sec-butyl acetate 64.23
    tert-butyl acetate 99.11
    decalin 12.58
    glycerin 1646.43
    diglyme 481.27
    acrylic acid 1166.33
    isopropyl myristate 37.14
    n-butyric acid 1015.21
    acetyl acetate 140.67
    di(2-ethylhexyl) phthalate 55.43
    ethyl propionate 103.57
    nitromethane 1556.18
    1,2-diethoxyethane 142.14
    benzonitrile 166.95
    trioctyl phosphate 45.87
    1-bromopropane 175.22
    gamma-valerolactone 672.7
    n-decanol 65.85
    triethyl phosphate 56.56
    4-methyl-2-pentanol 145.35
    propionitrile 419.26
    vinylene carbonate 284.54
    1,1,2-trichlorotrifluoroethane 842.4
    DMS 81.06
    cumene 20.89
    2-octanol 73.83
    2-hexanone 119.09
    octyl acetate 57.3
    limonene 59.61
    1,2-dimethoxyethane 624.98
    ethyl orthosilicate 58.8
    tributyl phosphate 51.97
    diacetone alcohol 247.38
    N,N-dimethylaniline 68.14
    acrylonitrile 558.96
    aniline 238.89
    1,3-propanediol 1818.38
    bromobenzene 70.04
    dibromomethane 352.02
    1,1,2,2-tetrachloroethane 451.39
    2-methyl-cyclohexyl acetate 74.37
    tetrabutyl urea 73.64
    diisobutyl methanol 67.7
    2-phenylethanol 142.53
    styrene 33.24
    dioctyl adipate 68.6
    dimethyl sulfate 170.37
    ethyl butyrate 111.0
    methyl lactate 292.64
    butyl lactate 110.76
    diethyl carbonate 67.16
    propanediol butyl ether 308.03
    triethyl orthoformate 82.21
    p-tert-butyltoluene 32.56
    methyl 4-tert-butylbenzoate 100.88
    morpholine 1122.49
    tert-butylamine 564.74
    n-dodecanol 48.74
    dimethoxymethane 425.19
    ethylene carbonate 221.29
    cyrene 186.79
    2-ethoxyethyl acetate 104.06
    2-ethylhexyl acetate 72.53
    1,2,4-trichlorobenzene 119.92
    4-methylpyridine 265.67
    dibutyl ether 68.45
    2,6-dimethyl-4-heptanol 67.7
    DEF 385.54
    dimethyl isosorbide 203.82
    tetrachloroethylene 386.58
    eugenol 137.45
    triacetin 116.49
    span 80 202.27
    1,4-butanediol 692.09
    1,1-dichloroethane 319.41
    2-methyl-1-pentanol 249.15
    methyl formate 642.32
    2-methyl-1-butanol 582.31
    n-decane 11.08
    butyronitrile 406.6
    3,7-dimethyl-1-octanol 92.31
    1-chlorooctane 42.75
    1-chlorotetradecane 16.31
    n-nonane 11.11
    undecane 8.06
    tert-butylcyclohexane 13.96
    cyclooctane 11.37
    cyclopentanol 797.92
    tetrahydropyran 534.21
    tert-amyl methyl ether 174.76
    2,5,8-trioxanonane 306.95
    1-hexene 67.76
    2-isopropoxyethanol 362.43
    2,2,2-trifluoroethanol 824.31
    methyl butyrate 178.29

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction