3-Isothujopsanone

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    25966-81-8

  • Properties

  • Applications

    3-Isothujopsanone (CAS 25966-81-8) is a bicyclic monoterpenoid ketone associated with conifer-derived essential oils and is mainly applied in R&D: as a reference material and internal/external standard for GC–MS/LC–MS profiling of essential oils and metabolomic traces; as a synthetic intermediate and terpenoid building block for structure–activity studies, derivatization, and tuning of volatility, stability, and odor; investigated for biological activities (antibacterial, antifungal, insect-repellent, antioxidant) to guide bio-based wood preservatives, natural material treatments, and eco-friendly pest management; as a component/reference in aroma research (woody, resinous, camphoraceous notes) and in assessing source/process variability; enabling chemical sensor development, QSAR modeling, and spectral library curation; any direct commercial use requires dedicated toxicology, stability, and regulatory compliance assessments.

1 2

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Cedarwood, Mulanje Widdringtonia whytei Rendle, fam. Cupressaceae 2.4%
Santolina insularis (Italy) 1b hydrodistilled Santolina insularis L., fam. Asteraceae (Compositae) 0.4%