3-Hydroxypropyl stearate

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  • Identifiers

    CAS number
    10108-23-3

    Molecular formula
    C21H42O3

    SMILES
    CCCCCCCCCCCCCCCCCC(=O)OCCCO

    Safety labels

  • Odor profile

    Fragrance
    Waxy 70.26%
    Fatty 65.12%
    Oily 56.8%
    Odorless 35.33%
    Sweet 33.2%
    Creamy 28.06%
    Fruity 26.4%
    Soapy 23.29%
    Clean 23.27%
    Dairy 21.33%

     

    Flavor
    Waxy 72.97%
    Fatty 52.32%
    Oily 50.75%
    Soapy 46.57%
    Mild 44.91%
    Coconut 39.22%
    Sweet 38.8%
    Creamy 36.69%
    Fruity 35.15%
    Fat 34.45%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    8.2

    pKa est.
    7.36 (neutral)

    Molecular weight
    342.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    432°C

    Flash point

    • 191.57 ˚C est.

  • Synonyms

    • 3-Hydroxypropyl stearate
    • Octadecanoic acid, 3-hydroxypropyl ester
    • 10108-23-3
    • PPN4O3JW0B
    • 1,3-Propanediol, monostearate
    • UNII-PPN4O3JW0B
    • 3-STEAROYLOXY-1-PROPANOL
    • DTXSID30865189
    • MONO-O-STEAROYL-1,3-PROPANEDIOL
    • RefChem:94394
    • DTXCID30813625
    • TVFNPSNDNZSCBM-UHFFFAOYSA-N
    • 3-hydroxypropyl octadecanoate
    • Stearic acid, 3-hydroxypropyl ester
    • Octadecanoic acid 3-hydroxypropyl ester
    • 25190-52-7
    • 3-Hydroxypropyl stearate #
    • 1,3-propanediol monostearate
    • SCHEMBL545425
    • NS00014005
    • 25190-52-7

  • Applications

    3-Hydroxypropyl stearate is commonly used in cosmetics and personal care as an emollient and conditioning agent, providing slip and a smooth feel on skin and hair. It also serves as a solvent and vehicle for active ingredients and fragrance oils in formulations. The ester can function as a plasticizer or processing aid in polymers and coatings/inks, improving flexibility and manufacturability. In pharmaceutical topical products, it may be employed as an excipient/vehicle. In household cleaning products, it can act as a mild solvent and lubricant to enhance texture and spread.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 14.96
    methanol 26.63
    isopropanol 22.35
    water 0.06
    ethyl acetate 173.26
    n-propanol 27.58
    acetone 99.33
    n-butanol 35.91
    acetonitrile 42.61
    DMF 227.13
    toluene 55.66
    isobutanol 35.15
    1,4-dioxane 168.33
    methyl acetate 108.75
    THF 515.42
    2-butanone 152.81
    n-pentanol 33.57
    sec-butanol 39.77
    n-hexane 15.18
    ethylene glycol 2.86
    NMP 672.3
    cyclohexane 99.01
    DMSO 349.4
    n-butyl acetate 222.76
    n-octanol 61.11
    chloroform 513.62
    n-propyl acetate 271.21
    acetic acid 72.51
    dichloromethane 546.95
    cyclohexanone 611.98
    propylene glycol 9.09
    isopropyl acetate 194.56
    DMAc 449.2
    2-ethoxyethanol 98.81
    isopentanol 60.69
    n-heptane 19.93
    ethyl formate 84.37
    1,2-dichloroethane 357.98
    n-hexanol 33.89
    2-methoxyethanol 95.61
    isobutyl acetate 182.56
    tetrachloromethane 127.65
    n-pentyl acetate 420.33
    transcutol 644.41
    n-heptanol 51.92
    ethylbenzene 52.5
    MIBK 211.4
    2-propoxyethanol 97.26
    tert-butanol 69.75
    MTBE 124.99
    2-butoxyethanol 163.82
    propionic acid 74.9
    o-xylene 67.44
    formic acid 16.0
    diethyl ether 81.98
    m-xylene 53.7
    p-xylene 84.44
    chlorobenzene 133.97
    dimethyl carbonate 51.8
    n-octane 10.71
    formamide 36.22
    cyclopentanone 590.19
    2-pentanone 183.09
    anisole 128.55
    cyclopentyl methyl ether 292.01
    gamma-butyrolactone 559.33
    1-methoxy-2-propanol 122.39
    pyridine 198.98
    3-pentanone 158.19
    furfural 384.83
    n-dodecane 6.22
    diethylene glycol 39.9
    diisopropyl ether 56.56
    tert-amyl alcohol 91.34
    acetylacetone 272.41
    n-hexadecane 7.82
    acetophenone 208.98
    methyl propionate 134.06
    isopentyl acetate 230.92
    trichloroethylene 619.32
    n-nonanol 63.2
    cyclohexanol 133.93
    benzyl alcohol 74.81
    2-ethylhexanol 56.26
    isooctanol 63.89
    dipropyl ether 137.82
    1,2-dichlorobenzene 202.53
    ethyl lactate 99.18
    propylene carbonate 328.23
    n-methylformamide 71.81
    2-pentanol 37.98
    n-pentane 9.34
    1-propoxy-2-propanol 135.68
    1-methoxy-2-propyl acetate 214.68
    2-(2-methoxypropoxy) propanol 158.43
    mesitylene 52.48
    ε-caprolactone 533.76
    p-cymene 55.46
    epichlorohydrin 496.12
    1,1,1-trichloroethane 422.14
    2-aminoethanol 11.86
    morpholine-4-carbaldehyde 401.15
    sulfolane 1116.31
    2,2,4-trimethylpentane 15.33
    2-methyltetrahydrofuran 354.74
    n-hexyl acetate 330.34
    isooctane 8.49
    2-(2-butoxyethoxy)ethanol 211.58
    sec-butyl acetate 208.43
    tert-butyl acetate 304.22
    decalin 34.31
    glycerin 22.01
    diglyme 550.3
    acrylic acid 53.62
    isopropyl myristate 100.19
    n-butyric acid 180.08
    acetyl acetate 136.34
    di(2-ethylhexyl) phthalate 80.62
    ethyl propionate 216.87
    nitromethane 197.55
    1,2-diethoxyethane 261.76
    benzonitrile 113.78
    trioctyl phosphate 62.42
    1-bromopropane 171.73
    gamma-valerolactone 750.5
    n-decanol 38.52
    triethyl phosphate 150.67
    4-methyl-2-pentanol 39.96
    propionitrile 54.79
    vinylene carbonate 241.96
    1,1,2-trichlorotrifluoroethane 373.87
    DMS 156.22
    cumene 46.68
    2-octanol 56.22
    2-hexanone 202.76
    octyl acetate 123.06
    limonene 108.76
    1,2-dimethoxyethane 319.58
    ethyl orthosilicate 145.96
    tributyl phosphate 93.49
    diacetone alcohol 254.79
    N,N-dimethylaniline 102.41
    acrylonitrile 62.26
    aniline 64.67
    1,3-propanediol 27.5
    bromobenzene 160.73
    dibromomethane 332.21
    1,1,2,2-tetrachloroethane 652.66
    2-methyl-cyclohexyl acetate 224.48
    tetrabutyl urea 150.1
    diisobutyl methanol 53.15
    2-phenylethanol 67.52
    styrene 62.02
    dioctyl adipate 190.17
    dimethyl sulfate 162.77
    ethyl butyrate 257.14
    methyl lactate 69.76
    butyl lactate 224.11
    diethyl carbonate 139.54
    propanediol butyl ether 128.35
    triethyl orthoformate 212.96
    p-tert-butyltoluene 51.82
    methyl 4-tert-butylbenzoate 261.3
    morpholine 250.65
    tert-butylamine 49.25
    n-dodecanol 26.79
    dimethoxymethane 126.64
    ethylene carbonate 223.38
    cyrene 189.04
    2-ethoxyethyl acetate 369.24
    2-ethylhexyl acetate 202.78
    1,2,4-trichlorobenzene 241.63
    4-methylpyridine 194.42
    dibutyl ether 182.28
    2,6-dimethyl-4-heptanol 53.15
    DEF 290.09
    dimethyl isosorbide 385.64
    tetrachloroethylene 416.23
    eugenol 181.99
    triacetin 386.97
    span 80 159.34
    1,4-butanediol 13.54
    1,1-dichloroethane 258.78
    2-methyl-1-pentanol 53.41
    methyl formate 53.56
    2-methyl-1-butanol 54.15
    n-decane 15.61
    butyronitrile 72.08
    3,7-dimethyl-1-octanol 69.81
    1-chlorooctane 84.2
    1-chlorotetradecane 23.74
    n-nonane 15.33
    undecane 9.01
    tert-butylcyclohexane 23.22
    cyclooctane 21.14
    cyclopentanol 128.05
    tetrahydropyran 284.96
    tert-amyl methyl ether 136.45
    2,5,8-trioxanonane 296.31
    1-hexene 39.64
    2-isopropoxyethanol 97.67
    2,2,2-trifluoroethanol 49.98
    methyl butyrate 333.41

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction