3-Hydroxyoctanoic acid

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  • Identifiers

    CAS number
    14292-27-4

    Molecular formula
    C8H16O3

    SMILES
    CCCCCC(CC(=O)O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fruity 77.7%
    Cheesy 64.77%
    Fatty 59.65%
    Green 51.14%
    Oily 49.12%
    Dairy 46.08%
    Waxy 40.92%
    Sour 40.55%
    Sweaty 36.4%
    Tropical 34.39%

     

    Flavor
    Cheese 44.94%
    Fatty 43.64%
    Odorless 37.62%
    Sour 36.71%
    Sweat 35.19%
    Oily 34.81%
    Green 33.36%
    Rancid 31.55%
    Cheesy 29.84%
    Acidic 28.1%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    6.9 (neutral)

    Molecular weight
    160.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    281°C

    Flash point

    • 136.67 ˚C est.

  • Synonyms

    • 3-HYDROXYOCTANOIC ACID
    • 14292-27-4
    • 3-hydroxycaprylic acid
    • Octanoic acid, 3-hydroxy-
    • 3-hydroxy-octanoic acid
    • 8M44B02CSJ
    • beta-hydroxyoctanoic acid
    • CHEBI:37098
    • DTXSID00864487
    • RefChem:911418
    • DTXCID30812996
    • 872-032-0
    • 88930-08-9
    • (+/-)-3-Hydroxyoctanoic acid
    • 3-hydroxy caprylic acid
    • Octanoic acid,3-hydroxy-
    • MFCD00133277
    • DL-beta-Hydroxycaprylic acid
    • 3-HYDROXYOCTANOICACID
    • UNII-8M44B02CSJ
    • 3-Hydroxycaprylic Acid; ss-Hydroxyoctanoic Acid; (+/-)-3-Hydroxyoctanoic Acid
    • 3-OH octanoic acid
    • 3-OH-caprylic acid
    • beta-OH-caprylic acid
    • beta-OH-octanoic acid
    • beta-hydroxycaprylic acid
    • SCHEMBL112858
    • orb1297921
    • SCHEMBL1361130
    • .BETA.-HYDROXYOCTANOIC ACID
    • 3HO
    • IBA79686
    • NDA93008
    • PAA29227
    • UBA98772
    • LMFA01050021
    • AKOS011680663
    • EBC-615312
    • PD077430
    • SY185981
    • TS-10038
    • (+/-)-3-Hydroxyoctanoic acid, >=97%
    • 3-HYDROXYOCTANOIC ACID, (+/-)-
    • HY-113058
    • CS-0059460
    • EN300-79364
    • C20793
    • F87768
    • F614433
    • Q15410154
    • Z982131990
    • 56D53B3D-0070-413F-9F5E-C9D4528A9786
    • 14292-27-4

  • Applications

    3-Hydroxyoctanoic acid (CAS 14292-27-4) is a hydroxy-functional fatty acid commonly used as a building block in the synthesis of specialty polymers and coatings, serving as an intermediate for polyesters and polyurethanes used in films, adhesives, and molded plastics. It is employed as a precursor to plasticizers and lubricant additives, helping to tune the flexibility and processability of polymer formulations. Through esterification, it can yield surfactant and emulsifier derivatives suitable for detergents, cleaners, or cosmetic formulations. In cosmetics and personal care, its hydroxy fatty acid structure enables the generation of emollient or conditioning esters. It may also participate in fragrance chemistry as a precursor to odorant esters and related aroma compounds. Use is formulation- and regulation-dependent.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 527.93
    methanol 1111.74
    isopropanol 271.49
    water 10.93
    ethyl acetate 99.63
    n-propanol 306.05
    acetone 282.36
    n-butanol 257.58
    acetonitrile 49.52
    DMF 834.46
    toluene 12.47
    isobutanol 231.63
    1,4-dioxane 189.5
    methyl acetate 66.77
    THF 829.96
    2-butanone 102.12
    n-pentanol 193.14
    sec-butanol 163.79
    n-hexane 13.27
    ethylene glycol 500.29
    NMP 706.12
    cyclohexane 8.18
    DMSO 1620.48
    n-butyl acetate 128.87
    n-octanol 89.39
    chloroform 31.38
    n-propyl acetate 83.9
    acetic acid 636.57
    dichloromethane 25.99
    cyclohexanone 316.25
    propylene glycol 588.24
    isopropyl acetate 96.7
    DMAc 386.57
    2-ethoxyethanol 358.21
    isopentanol 262.25
    n-heptane 8.02
    ethyl formate 100.98
    1,2-dichloroethane 37.56
    n-hexanol 279.14
    2-methoxyethanol 884.64
    isobutyl acetate 71.45
    tetrachloromethane 12.18
    n-pentyl acetate 65.87
    transcutol 791.54
    n-heptanol 103.65
    ethylbenzene 14.43
    MIBK 151.77
    2-propoxyethanol 505.02
    tert-butanol 487.0
    MTBE 89.16
    2-butoxyethanol 214.75
    propionic acid 322.61
    o-xylene 20.89
    formic acid 425.42
    diethyl ether 37.78
    m-xylene 29.79
    p-xylene 20.45
    chlorobenzene 22.19
    dimethyl carbonate 59.47
    n-octane 2.96
    formamide 358.94
    cyclopentanone 533.11
    2-pentanone 153.31
    anisole 56.75
    cyclopentyl methyl ether 245.15
    gamma-butyrolactone 583.24
    1-methoxy-2-propanol 634.51
    pyridine 61.58
    3-pentanone 61.41
    furfural 335.22
    n-dodecane 2.82
    diethylene glycol 519.31
    diisopropyl ether 30.15
    tert-amyl alcohol 285.0
    acetylacetone 243.5
    n-hexadecane 3.13
    acetophenone 80.21
    methyl propionate 101.06
    isopentyl acetate 133.56
    trichloroethylene 77.59
    n-nonanol 74.42
    cyclohexanol 237.29
    benzyl alcohol 91.1
    2-ethylhexanol 113.73
    isooctanol 84.71
    dipropyl ether 67.21
    1,2-dichlorobenzene 32.09
    ethyl lactate 102.19
    propylene carbonate 248.95
    n-methylformamide 413.54
    2-pentanol 144.58
    n-pentane 5.91
    1-propoxy-2-propanol 346.02
    1-methoxy-2-propyl acetate 182.12
    2-(2-methoxypropoxy) propanol 213.62
    mesitylene 29.57
    ε-caprolactone 259.16
    p-cymene 22.2
    epichlorohydrin 329.36
    1,1,1-trichloroethane 35.16
    2-aminoethanol 716.03
    morpholine-4-carbaldehyde 525.66
    sulfolane 900.78
    2,2,4-trimethylpentane 7.02
    2-methyltetrahydrofuran 314.1
    n-hexyl acetate 121.35
    isooctane 8.93
    2-(2-butoxyethoxy)ethanol 321.22
    sec-butyl acetate 57.3
    tert-butyl acetate 156.67
    decalin 8.68
    glycerin 763.67
    diglyme 434.33
    acrylic acid 281.32
    isopropyl myristate 43.64
    n-butyric acid 417.52
    acetyl acetate 73.29
    di(2-ethylhexyl) phthalate 65.57
    ethyl propionate 71.88
    nitromethane 471.38
    1,2-diethoxyethane 92.25
    benzonitrile 64.28
    trioctyl phosphate 55.42
    1-bromopropane 16.27
    gamma-valerolactone 611.61
    n-decanol 53.36
    triethyl phosphate 49.3
    4-methyl-2-pentanol 125.29
    propionitrile 53.88
    vinylene carbonate 159.61
    1,1,2-trichlorotrifluoroethane 366.21
    DMS 78.39
    cumene 19.83
    2-octanol 57.95
    2-hexanone 108.74
    octyl acetate 61.8
    limonene 36.55
    1,2-dimethoxyethane 367.53
    ethyl orthosilicate 47.14
    tributyl phosphate 62.46
    diacetone alcohol 401.49
    N,N-dimethylaniline 59.17
    acrylonitrile 81.98
    aniline 53.56
    1,3-propanediol 668.32
    bromobenzene 16.24
    dibromomethane 19.17
    1,1,2,2-tetrachloroethane 84.14
    2-methyl-cyclohexyl acetate 90.14
    tetrabutyl urea 88.73
    diisobutyl methanol 67.19
    2-phenylethanol 108.9
    styrene 13.81
    dioctyl adipate 82.3
    dimethyl sulfate 156.77
    ethyl butyrate 78.06
    methyl lactate 184.42
    butyl lactate 115.35
    diethyl carbonate 48.44
    propanediol butyl ether 309.89
    triethyl orthoformate 63.19
    p-tert-butyltoluene 24.67
    methyl 4-tert-butylbenzoate 120.92
    morpholine 356.7
    tert-butylamine 184.38
    n-dodecanol 37.62
    dimethoxymethane 259.77
    ethylene carbonate 142.33
    cyrene 213.8
    2-ethoxyethyl acetate 91.21
    2-ethylhexyl acetate 84.95
    1,2,4-trichlorobenzene 45.24
    4-methylpyridine 71.27
    dibutyl ether 42.55
    2,6-dimethyl-4-heptanol 67.19
    DEF 193.46
    dimethyl isosorbide 338.99
    tetrachloroethylene 65.94
    eugenol 135.67
    triacetin 117.14
    span 80 211.53
    1,4-butanediol 266.29
    1,1-dichloroethane 24.66
    2-methyl-1-pentanol 162.07
    methyl formate 228.17
    2-methyl-1-butanol 198.49
    n-decane 4.3
    butyronitrile 79.49
    3,7-dimethyl-1-octanol 90.67
    1-chlorooctane 21.08
    1-chlorotetradecane 8.94
    n-nonane 4.07
    undecane 3.36
    tert-butylcyclohexane 10.95
    cyclooctane 4.17
    cyclopentanol 411.63
    tetrahydropyran 144.54
    tert-amyl methyl ether 82.07
    2,5,8-trioxanonane 332.5
    1-hexene 33.89
    2-isopropoxyethanol 227.27
    2,2,2-trifluoroethanol 164.38
    methyl butyrate 115.82

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction