3-Glyceryl ascorbate

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  • Identifiers

    CAS number
    1120360-11-3

    Molecular formula
    C9H14O8

    SMILES
    C([C@@H]([C@@H]1C(=C(C(=O)O1)O)OCC(CO)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 64.54%
    Sweet 37.45%
    Caramellic 33.18%
    Buttery 24.24%
    Clean 19.64%
    Alcoholic 19.25%
    Milky 18.56%
    Savory 18.36%
    Burnt 15.65%
    Creamy 15.42%

     

    Flavor
    Odorless 55.61%
    Very mild 36.76%
    Sweet-like 30.4%
    Bitter 30.24%
    Sweet 27.93%
    Bland 27.67%
    Very slight 20.77%
    Yeast 19.84%
    Caramellic 19.83%
    Mild 19.58%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -3.2

    pKa est.
    4.77 (weak acid)

    Molecular weight
    250.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1364°C

    Flash point

    • 256.56 ˚C est.

  • Synonyms

    • 3-Glyceryl ascorbate
    • Amitose 3GA
    • UNII-3R1Q5X5GGO
    • 3R1Q5X5GGO
    • L-Ascorbic acid, 3-O-(2,3-dihydroxypropyl)-
    • 1120360-11-3
    • DTXSID70149839
    • RefChem:94000
    • DTXCID2072330
    • 3-GLYCERYL ASCORBATE [INCI]
    • glycerylascorbate
    • 3-o-glyceryl ascorbic acid
    • SCHEMBL2071534
    • Q27257920
    • (5R)-5-[(1S)-1,2-Dihydroxyethyl]-4-(2,3-dihydroxypropoxy)-3-hydroxyfuran-2(5H)-one
    • 1120360-11-3

  • Applications

    3-Glyceryl ascorbate (CAS 1120360-11-3) is used primarily as a lipophilic antioxidant and formulation stabilizer across several industries. In cosmetics and personal care, it acts as an antioxidant for lipid-rich products and as a vitamin C derivative with skin-conditioning potential. It is often evaluated as an intermediate or excipient in the synthesis of other ascorbate esters for pharmaceutical or nutraceutical applications. In food processing, it may serve as an antioxidant to slow oxidative spoilage of fats and oils. In coatings, inks, and polymer formulations, it can act as a stabilizer to improve oxidative stability of formulations. In household products, it may be employed as an antioxidant/stabilizer component, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 5.98
    methanol 51.38
    isopropanol 1.79
    water 553.33
    ethyl acetate 0.28
    n-propanol 2.34
    acetone 0.89
    n-butanol 1.26
    acetonitrile 0.54
    DMF 194.56
    toluene 0.22
    isobutanol 0.9
    1,4-dioxane 2.63
    methyl acetate 0.48
    THF 2.17
    2-butanone 0.53
    n-pentanol 0.7
    sec-butanol 1.19
    n-hexane 0.05
    ethylene glycol 180.76
    NMP 150.26
    cyclohexane 0.44
    DMSO 572.62
    n-butyl acetate 0.48
    n-octanol 1.07
    chloroform 0.18
    n-propyl acetate 0.28
    acetic acid 20.42
    dichloromethane 0.33
    cyclohexanone 2.06
    propylene glycol 59.21
    isopropyl acetate 0.27
    DMAc 90.71
    2-ethoxyethanol 16.18
    isopentanol 0.87
    n-heptane 0.3
    ethyl formate 1.14
    1,2-dichloroethane 0.46
    n-hexanol 1.17
    2-methoxyethanol 64.72
    isobutyl acetate 0.14
    tetrachloromethane 0.13
    n-pentyl acetate 0.52
    transcutol 20.36
    n-heptanol 1.41
    ethylbenzene 0.2
    MIBK 0.4
    2-propoxyethanol 9.87
    tert-butanol 2.55
    MTBE 0.38
    2-butoxyethanol 6.82
    propionic acid 5.08
    o-xylene 0.54
    formic acid 500.23
    diethyl ether 0.29
    m-xylene 0.32
    p-xylene 0.21
    chlorobenzene 0.11
    dimethyl carbonate 4.18
    n-octane 0.15
    formamide 356.03
    cyclopentanone 2.78
    2-pentanone 0.45
    anisole 0.54
    cyclopentyl methyl ether 1.21
    gamma-butyrolactone 6.02
    1-methoxy-2-propanol 26.9
    pyridine 1.47
    3-pentanone 0.55
    furfural 12.06
    n-dodecane 0.09
    diethylene glycol 51.25
    diisopropyl ether 0.16
    tert-amyl alcohol 2.03
    acetylacetone 1.49
    n-hexadecane 0.1
    acetophenone 1.32
    methyl propionate 1.29
    isopentyl acetate 0.45
    trichloroethylene 0.61
    n-nonanol 1.04
    cyclohexanol 2.55
    benzyl alcohol 2.06
    2-ethylhexanol 0.71
    isooctanol 0.98
    dipropyl ether 0.69
    1,2-dichlorobenzene 0.25
    ethyl lactate 4.19
    propylene carbonate 2.59
    n-methylformamide 65.86
    2-pentanol 0.7
    n-pentane 0.11
    1-propoxy-2-propanol 6.19
    1-methoxy-2-propyl acetate 2.33
    2-(2-methoxypropoxy) propanol 8.6
    mesitylene 0.34
    ε-caprolactone 2.78
    p-cymene 0.48
    epichlorohydrin 2.13
    1,1,1-trichloroethane 0.1
    2-aminoethanol 86.35
    morpholine-4-carbaldehyde 68.54
    sulfolane 57.04
    2,2,4-trimethylpentane 0.08
    2-methyltetrahydrofuran 0.96
    n-hexyl acetate 0.69
    isooctane 0.04
    2-(2-butoxyethoxy)ethanol 10.2
    sec-butyl acetate 0.18
    tert-butyl acetate 0.58
    decalin 0.12
    glycerin 231.33
    diglyme 16.44
    acrylic acid 14.93
    isopropyl myristate 0.39
    n-butyric acid 2.3
    acetyl acetate 0.44
    di(2-ethylhexyl) phthalate 1.13
    ethyl propionate 0.39
    nitromethane 17.21
    1,2-diethoxyethane 1.06
    benzonitrile 0.63
    trioctyl phosphate 1.05
    1-bromopropane 0.12
    gamma-valerolactone 12.03
    n-decanol 0.84
    triethyl phosphate 1.18
    4-methyl-2-pentanol 0.5
    propionitrile 0.41
    vinylene carbonate 3.28
    1,1,2-trichlorotrifluoroethane 29.16
    DMS 1.39
    cumene 0.2
    2-octanol 0.71
    2-hexanone 0.28
    octyl acetate 0.62
    limonene 0.7
    1,2-dimethoxyethane 6.67
    ethyl orthosilicate 0.93
    tributyl phosphate 0.82
    diacetone alcohol 4.96
    N,N-dimethylaniline 1.35
    acrylonitrile 1.53
    aniline 1.06
    1,3-propanediol 35.95
    bromobenzene 0.09
    dibromomethane 0.18
    1,1,2,2-tetrachloroethane 0.86
    2-methyl-cyclohexyl acetate 0.83
    tetrabutyl urea 2.19
    diisobutyl methanol 0.65
    2-phenylethanol 1.95
    styrene 0.17
    dioctyl adipate 1.0
    dimethyl sulfate 21.47
    ethyl butyrate 0.58
    methyl lactate 18.5
    butyl lactate 2.63
    diethyl carbonate 0.57
    propanediol butyl ether 12.17
    triethyl orthoformate 0.99
    p-tert-butyltoluene 0.5
    methyl 4-tert-butylbenzoate 3.67
    morpholine 5.96
    tert-butylamine 0.97
    n-dodecanol 0.68
    dimethoxymethane 14.99
    ethylene carbonate 1.86
    cyrene 22.01
    2-ethoxyethyl acetate 1.1
    2-ethylhexyl acetate 0.36
    1,2,4-trichlorobenzene 0.43
    4-methylpyridine 0.86
    dibutyl ether 0.36
    2,6-dimethyl-4-heptanol 0.65
    DEF 6.18
    dimethyl isosorbide 10.99
    tetrachloroethylene 0.89
    eugenol 4.89
    triacetin 2.26
    span 80 8.05
    1,4-butanediol 14.66
    1,1-dichloroethane 0.08
    2-methyl-1-pentanol 0.56
    methyl formate 22.45
    2-methyl-1-butanol 0.89
    n-decane 0.14
    butyronitrile 0.24
    3,7-dimethyl-1-octanol 0.74
    1-chlorooctane 0.23
    1-chlorotetradecane 0.13
    n-nonane 0.14
    undecane 0.11
    tert-butylcyclohexane 0.06
    cyclooctane 0.27
    cyclopentanol 2.75
    tetrahydropyran 0.79
    tert-amyl methyl ether 0.65
    2,5,8-trioxanonane 15.37
    1-hexene 0.08
    2-isopropoxyethanol 4.86
    2,2,2-trifluoroethanol 26.91
    methyl butyrate 0.6

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction