3-Ethyl-4-methyl-2,5-dihydrofuran-2,5-dione

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    3552-33-8

    Molecular formula
    C7H8O3

    SMILES
    CCC1=C(C(=O)OC1=O)C

    Safety labels

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

  • Odor profile

    Caramellic 71.22%
    Sweet 64.2%
    Burnt 50.81%
    Tobacco 38.57%
    Nutty 36.74%
    Coumarinic 36.39%
    Fruity 34.37%
    Buttery 33.15%
    Lactonic 32.71%
    Mint 32.56%

    Scent© AI

  • Properties

    XLogP3-AA
    1.1

    pKa est.
    7.22 (neutral)

    Molecular weight
    140.14 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point est.
    232°C

    Flash point est.
    104.34 ˚C

  • Synonyms

    • 3552-33-8
    • Ethylmethylmaleic anhydride
    • 3-ethyl-4-methylfuran-2,5-dione
    • 2-Ethyl-3-methylmaleic Anhydride
    • 2,5-Furandione,3-ethyl-4-methyl-
    • 2,5-Furandione, 3-ethyl-4-methyl-
    • 3-ethyl-4-methyl-2,5-dihydrofuran-2,5-dione
    • 3-Ethyl-4-methyl-2,5-furandione
    • Methylathylmaleinsaureanhydrid
    • SCHEMBL3292856
    • DTXSID00189026
    • DB-314004
    • NS00127368
    • 102-106-3

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 161.13
    methanol 215.73
    isopropanol 127.92
    water 1.22
    ethyl acetate 245.98
    n-propanol 132.51
    acetone 354.9
    n-butanol 135.74
    acetonitrile 273.75
    DMF 792.65
    toluene 136.46
    isobutanol 91.63
    1,4-dioxane 537.86
    methyl acetate 274.75
    THF 655.92
    2-butanone 268.63
    n-pentanol 117.05
    sec-butanol 130.97
    n-hexane 14.53
    ethylene glycol 51.33
    NMP 686.7
    cyclohexane 14.56
    DMSO 652.8
    n-butyl acetate 136.82
    n-octanol 56.12
    chloroform 553.58
    n-propyl acetate 143.29
    acetic acid 272.17
    dichloromethane 606.87
    cyclohexanone 360.73
    propylene glycol 46.98
    isopropyl acetate 144.76
    DMAc 339.19
    2-ethoxyethanol 261.51
    isopentanol 127.17
    n-heptane 7.5
    ethyl formate 162.6
    1,2-dichloroethane 431.63
    n-hexanol 106.44
    2-methoxyethanol 417.49
    isobutyl acetate 74.66
    tetrachloromethane 68.33
    n-pentyl acetate 130.88
    transcutol 501.5
    n-heptanol 63.33
    ethylbenzene 78.64
    MIBK 152.93
    2-propoxyethanol 269.78
    tert-butanol 181.78
    MTBE 161.38
    2-butoxyethanol 165.66
    propionic acid 165.73
    o-xylene 84.26
    formic acid 144.33
    diethyl ether 200.51
    m-xylene 98.93
    p-xylene 97.9
    chlorobenzene 256.01
    dimethyl carbonate 176.29
    n-octane 4.44
    formamide 333.29
    cyclopentanone 520.12
    2-pentanone 229.13
    anisole 226.75
    cyclopentyl methyl ether 229.3
    gamma-butyrolactone 719.58
    1-methoxy-2-propanol 290.3
    pyridine 446.41
    3-pentanone 172.12
    furfural 648.7
    n-dodecane 4.75
    diethylene glycol 219.7
    diisopropyl ether 58.69
    tert-amyl alcohol 160.25
    acetylacetone 313.23
    n-hexadecane 5.69
    acetophenone 197.29
    methyl propionate 235.72
    isopentyl acetate 121.94
    trichloroethylene 893.74
    n-nonanol 56.6
    cyclohexanol 127.14
    benzyl alcohol 165.97
    2-ethylhexanol 59.05
    isooctanol 51.1
    dipropyl ether 67.04
    1,2-dichlorobenzene 246.63
    ethyl lactate 81.41
    propylene carbonate 294.58
    n-methylformamide 418.03
    2-pentanol 103.78
    n-pentane 12.23
    1-propoxy-2-propanol 152.93
    1-methoxy-2-propyl acetate 182.85
    2-(2-methoxypropoxy) propanol 156.74
    mesitylene 60.88
    ε-caprolactone 313.51
    p-cymene 38.26
    epichlorohydrin 755.14
    1,1,1-trichloroethane 317.93
    2-aminoethanol 97.38
    morpholine-4-carbaldehyde 628.74
    sulfolane 839.6
    2,2,4-trimethylpentane 9.21
    2-methyltetrahydrofuran 388.59
    n-hexyl acetate 180.87
    isooctane 8.34
    2-(2-butoxyethoxy)ethanol 220.12
    sec-butyl acetate 100.58
    tert-butyl acetate 187.98
    decalin 15.61
    glycerin 96.83
    diglyme 420.69
    acrylic acid 196.78
    isopropyl myristate 67.69
    n-butyric acid 200.81
    acetyl acetate 169.85
    di(2-ethylhexyl) phthalate 72.19
    ethyl propionate 144.81
    nitromethane 737.39
    1,2-diethoxyethane 172.43
    benzonitrile 223.08
    trioctyl phosphate 50.27
    1-bromopropane 169.98
    gamma-valerolactone 697.69
    n-decanol 42.95
    triethyl phosphate 63.9
    4-methyl-2-pentanol 67.75
    propionitrile 182.07
    vinylene carbonate 314.74
    1,1,2-trichlorotrifluoroethane 376.71
    DMS 185.89
    cumene 50.99
    2-octanol 47.86
    2-hexanone 157.86
    octyl acetate 89.5
    limonene 50.21
    1,2-dimethoxyethane 423.98
    ethyl orthosilicate 59.29
    tributyl phosphate 61.03
    diacetone alcohol 221.03
    N,N-dimethylaniline 138.36
    acrylonitrile 311.51
    aniline 184.8
    1,3-propanediol 167.8
    bromobenzene 263.57
    dibromomethane 333.71
    1,1,2,2-tetrachloroethane 528.92
    2-methyl-cyclohexyl acetate 97.12
    tetrabutyl urea 84.98
    diisobutyl methanol 41.18
    2-phenylethanol 151.25
    styrene 111.08
    dioctyl adipate 93.55
    dimethyl sulfate 318.75
    ethyl butyrate 97.33
    methyl lactate 135.99
    butyl lactate 92.34
    diethyl carbonate 78.5
    propanediol butyl ether 117.01
    triethyl orthoformate 72.52
    p-tert-butyltoluene 41.79
    methyl 4-tert-butylbenzoate 172.91
    morpholine 538.02
    tert-butylamine 95.7
    n-dodecanol 32.15
    dimethoxymethane 433.16
    ethylene carbonate 224.91
    cyrene 178.0
    2-ethoxyethyl acetate 195.15
    2-ethylhexyl acetate 94.03
    1,2,4-trichlorobenzene 286.79
    4-methylpyridine 419.99
    dibutyl ether 66.78
    2,6-dimethyl-4-heptanol 41.18
    DEF 284.8
    dimethyl isosorbide 300.2
    tetrachloroethylene 330.52
    eugenol 176.53
    triacetin 148.57
    span 80 126.63
    1,4-butanediol 69.37
    1,1-dichloroethane 312.01
    2-methyl-1-pentanol 115.17
    methyl formate 319.03
    2-methyl-1-butanol 114.37
    n-decane 7.16
    butyronitrile 169.63
    3,7-dimethyl-1-octanol 59.0
    1-chlorooctane 39.35
    1-chlorotetradecane 18.69
    n-nonane 6.01
    undecane 5.72
    tert-butylcyclohexane 13.62
    cyclooctane 6.37
    cyclopentanol 162.36
    tetrahydropyran 304.15
    tert-amyl methyl ether 132.0
    2,5,8-trioxanonane 279.69
    1-hexene 59.24
    2-isopropoxyethanol 167.02
    2,2,2-trifluoroethanol 138.68
    methyl butyrate 173.72

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Hedyotis diffusa (Malaysia) Hedyotis diffusa Willd. (syn. Oldenlandia diffusa Roxb.), fam. Rubiaceae 0.5%