3-Ethoxypropionic acid

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  • Identifiers

    CAS number
    4324-38-3

    Molecular formula
    C5H10O3

    SMILES
    CCOCCC(=O)O

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fruity 86.86%
    Ethereal 48.38%
    Sour 43.51%
    Cheesy 41.2%
    Sharp 41.1%
    Pungent 39.66%
    Fermented 35.87%
    Caramellic 35.51%
    Winey 34.94%
    Sweaty 31.38%

    Scent© AI

  • Properties

    XLogP3-AA
    -0.1

    pKa est.
    7.55 (neutral)

    Molecular weight
    118.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    218°C

    Flash point est.
    93.67 ˚C

  • Synonyms

    • 3-Ethoxypropanoic acid
    • 3-Ethoxypropionic acid
    • 4324-38-3
    • 1331-11-9
    • PROPANOIC ACID, 3-ETHOXY-
    • Propionic acid, ethoxy-
    • EINECS 224-357-9
    • AI3-52370
    • NSC 8118
    • NSC 16879
    • 3-Ethoxypropanoicacid
    • 3-ethoxy-propionic acid
    • NSC-8118
    • O-Ethylhydracrylic Acid
    • 3-Ethoxypropanoic acid #
    • .beta.-Ethoxypropionic acid
    • SCHEMBL27523
    • JRXXEXVXTFEBIY-UHFFFAOYSA-
    • DTXSID70863366
    • NSC8118
    • ALBB-022360
    • EAA32438
    • NSC16879
    • MFCD00058997
    • NSC-16879
    • AKOS000183015
    • FS-4045
    • DB-252464
    • CS-0216898
    • E0053
    • NS00045828
    • EN300-64537
    • F11739
    • Z316258938
    • InChI=1/C5H10O3/c1-2-8-4-3-5(6)7/h2-4H2,1H3,(H,6,7)
    • 224-357-9
    • 622-870-6

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 243.25
    methanol 442.83
    isopropanol 138.36
    water 180.68
    ethyl acetate 41.92
    n-propanol 123.55
    acetone 112.25
    n-butanol 110.77
    acetonitrile 64.84
    DMF 636.21
    toluene 5.67
    isobutanol 80.6
    1,4-dioxane 176.38
    methyl acetate 58.68
    THF 216.3
    2-butanone 45.08
    n-pentanol 54.36
    sec-butanol 74.23
    n-hexane 2.79
    ethylene glycol 278.1
    NMP 483.44
    cyclohexane 5.05
    DMSO 443.84
    n-butyl acetate 22.99
    n-octanol 34.05
    chloroform 33.89
    n-propyl acetate 22.25
    acetic acid 359.42
    dichloromethane 49.91
    cyclohexanone 103.73
    propylene glycol 223.94
    isopropyl acetate 27.39
    DMAc 412.04
    2-ethoxyethanol 149.09
    isopentanol 77.62
    n-heptane 3.61
    ethyl formate 78.06
    1,2-dichloroethane 30.83
    n-hexanol 43.19
    2-methoxyethanol 394.36
    isobutyl acetate 16.55
    tetrachloromethane 9.42
    n-pentyl acetate 19.54
    transcutol 282.61
    n-heptanol 24.89
    ethylbenzene 5.82
    MIBK 26.79
    2-propoxyethanol 124.68
    tert-butanol 161.19
    MTBE 39.13
    2-butoxyethanol 67.29
    propionic acid 178.58
    o-xylene 11.47
    formic acid 364.16
    diethyl ether 24.91
    m-xylene 9.07
    p-xylene 9.35
    chlorobenzene 12.33
    dimethyl carbonate 44.28
    n-octane 1.54
    formamide 323.5
    cyclopentanone 142.64
    2-pentanone 39.12
    anisole 27.94
    cyclopentyl methyl ether 57.6
    gamma-butyrolactone 219.71
    1-methoxy-2-propanol 225.42
    pyridine 45.78
    3-pentanone 25.93
    furfural 199.84
    n-dodecane 2.08
    diethylene glycol 197.79
    diisopropyl ether 9.05
    tert-amyl alcohol 95.57
    acetylacetone 66.0
    n-hexadecane 2.25
    acetophenone 34.32
    methyl propionate 57.16
    isopentyl acetate 24.45
    trichloroethylene 47.46
    n-nonanol 30.82
    cyclohexanol 88.29
    benzyl alcohol 41.88
    2-ethylhexanol 24.54
    isooctanol 21.28
    dipropyl ether 20.82
    1,2-dichlorobenzene 19.46
    ethyl lactate 43.99
    propylene carbonate 109.46
    n-methylformamide 275.47
    2-pentanol 44.52
    n-pentane 3.04
    1-propoxy-2-propanol 75.36
    1-methoxy-2-propyl acetate 46.61
    2-(2-methoxypropoxy) propanol 94.82
    mesitylene 8.62
    ε-caprolactone 105.89
    p-cymene 9.54
    epichlorohydrin 123.9
    1,1,1-trichloroethane 22.68
    2-aminoethanol 305.59
    morpholine-4-carbaldehyde 404.9
    sulfolane 303.67
    2,2,4-trimethylpentane 3.01
    2-methyltetrahydrofuran 99.13
    n-hexyl acetate 38.95
    isooctane 2.06
    2-(2-butoxyethoxy)ethanol 125.56
    sec-butyl acetate 15.9
    tert-butyl acetate 35.63
    decalin 3.76
    glycerin 357.14
    diglyme 190.31
    acrylic acid 194.5
    isopropyl myristate 18.59
    n-butyric acid 146.74
    acetyl acetate 39.61
    di(2-ethylhexyl) phthalate 31.27
    ethyl propionate 28.49
    nitromethane 320.24
    1,2-diethoxyethane 40.12
    benzonitrile 36.57
    trioctyl phosphate 22.95
    1-bromopropane 11.65
    gamma-valerolactone 256.47
    n-decanol 23.3
    triethyl phosphate 25.3
    4-methyl-2-pentanol 27.42
    propionitrile 46.08
    vinylene carbonate 104.38
    1,1,2-trichlorotrifluoroethane 185.17
    DMS 41.04
    cumene 8.4
    2-octanol 17.05
    2-hexanone 22.43
    octyl acetate 25.87
    limonene 14.33
    1,2-dimethoxyethane 175.33
    ethyl orthosilicate 22.84
    tributyl phosphate 27.5
    diacetone alcohol 85.72
    N,N-dimethylaniline 33.17
    acrylonitrile 73.57
    aniline 32.92
    1,3-propanediol 288.36
    bromobenzene 8.39
    dibromomethane 22.83
    1,1,2,2-tetrachloroethane 45.56
    2-methyl-cyclohexyl acetate 29.91
    tetrabutyl urea 41.94
    diisobutyl methanol 17.33
    2-phenylethanol 34.17
    styrene 6.52
    dioctyl adipate 38.35
    dimethyl sulfate 95.51
    ethyl butyrate 27.13
    methyl lactate 101.83
    butyl lactate 36.24
    diethyl carbonate 25.1
    propanediol butyl ether 101.57
    triethyl orthoformate 26.36
    p-tert-butyltoluene 9.68
    methyl 4-tert-butylbenzoate 58.1
    morpholine 216.17
    tert-butylamine 75.5
    n-dodecanol 17.72
    dimethoxymethane 153.85
    ethylene carbonate 82.8
    cyrene 100.79
    2-ethoxyethyl acetate 33.58
    2-ethylhexyl acetate 17.74
    1,2,4-trichlorobenzene 26.59
    4-methylpyridine 48.33
    dibutyl ether 21.14
    2,6-dimethyl-4-heptanol 17.33
    DEF 115.14
    dimethyl isosorbide 130.03
    tetrachloroethylene 32.39
    eugenol 60.34
    triacetin 61.2
    span 80 87.25
    1,4-butanediol 100.19
    1,1-dichloroethane 19.86
    2-methyl-1-pentanol 44.93
    methyl formate 181.17
    2-methyl-1-butanol 70.52
    n-decane 2.84
    butyronitrile 49.65
    3,7-dimethyl-1-octanol 30.21
    1-chlorooctane 9.99
    1-chlorotetradecane 5.58
    n-nonane 2.54
    undecane 2.37
    tert-butylcyclohexane 3.87
    cyclooctane 1.96
    cyclopentanol 126.02
    tetrahydropyran 75.92
    tert-amyl methyl ether 33.69
    2,5,8-trioxanonane 163.75
    1-hexene 7.6
    2-isopropoxyethanol 76.14
    2,2,2-trifluoroethanol 155.2
    methyl butyrate 42.03

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction