3-Dodecyldihydro-2(3H)-furanone, (+/-)-

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  • Identifiers

    CAS number
    73263-36-2

    Molecular formula
    C16H30O2

    SMILES
    CCCCCCCCCCCCC1CCOC1=O

  • Odor profile

    Fragrance
    Fatty 75.84%
    Waxy 72.6%
    Oily 53.16%
    Creamy 46.52%
    Dairy 41.78%
    Sweet 39.5%
    Milky 38.86%
    Coconut 37.14%
    Buttery 36.26%
    Peach 33.52%

     

    Flavor
    Waxy 66.34%
    Fatty 64.69%
    Creamy 51.58%
    Oily 49.27%
    Coconut 48.16%
    Fruity 40.57%
    Peach 39.96%
    Sweet 39.7%
    Fat 35.94%
    Mild 34.33%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    6.5

    pKa est.
    7.48 (neutral)

    Molecular weight
    254.41 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    339°C

    Flash point

    • 147.14 ˚C est.

  • Synonyms

    • 3-Dodecyldihydrofuran-2(3H)-one
    • 2(3H)-Furanone, 3-dodecyldihydro-
    • 73263-36-2
    • EINECS 277-333-5
    • 34X20FF6LR
    • alpha-Dodecyl-gamma-butyrolactone
    • 3-Dodecyldihydro-2(3H)-furanone, (+/-)-
    • DTXSID50868238
    • .ALPHA.-(.BETA.-HYDROXYETHYL)MYRISTIC ACID LACTONE, (+/-)-
    • UNII-34X20FF6LR
    • SCHEMBL11392390
    • DTXCID00816365
    • CKVQBYJDENROIT-UHFFFAOYSA-N
    • (+/-)-3-dodecyldihydro-2(3H)-furanone
    • NS00012355
    • Q27256396
    • ALPHA-(BETA-HYDROXYETHYL)MYRISTIC ACID LACTONE, (+/-)-

  • Applications

    3-Dodecyldihydro-2(3H)-furanone, (+/-)- (CAS 73263-36-2) is primarily used as a fragrance ingredient and aroma compound in perfumery and cosmetics, where its long aliphatic side chain can contribute to fragrance character and longevity; it is commonly evaluated as a flavor/aroma additive in select applications, subject to regulatory approvals. The compound can serve as an intermediate in fragrance synthesis for bespoke odor profiles and may function as a scent fixative or modifier in household products and cleaners. In industrial settings, it is sometimes used as a specialty intermediate for the preparation of other lactone-based inputs in fragrance and flavor portfolios.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1334.48
    methanol 869.63
    isopropanol 1691.66
    water 0.03
    ethyl acetate 4409.43
    n-propanol 1474.91
    acetone 4042.78
    n-butanol 1567.15
    acetonitrile 1855.14
    DMF 2786.08
    toluene 1310.09
    isobutanol 1266.4
    1,4-dioxane 3115.52
    methyl acetate 2434.28
    THF 5756.55
    2-butanone 3532.39
    n-pentanol 964.22
    sec-butanol 1488.89
    n-hexane 380.02
    ethylene glycol 48.12
    NMP 2636.8
    cyclohexane 952.7
    DMSO 2274.75
    n-butyl acetate 3270.76
    n-octanol 522.4
    chloroform 6785.04
    n-propyl acetate 3761.16
    acetic acid 897.91
    dichloromethane 6936.09
    cyclohexanone 6322.5
    propylene glycol 172.94
    isopropyl acetate 3606.15
    DMAc 2503.39
    2-ethoxyethanol 1451.21
    isopentanol 1643.45
    n-heptane 200.01
    ethyl formate 1696.35
    1,2-dichloroethane 4788.95
    n-hexanol 859.84
    2-methoxyethanol 1787.94
    isobutyl acetate 2209.83
    tetrachloromethane 1312.76
    n-pentyl acetate 2547.73
    transcutol 4905.95
    n-heptanol 513.02
    ethylbenzene 754.5
    MIBK 2391.7
    2-propoxyethanol 1548.47
    tert-butanol 2170.05
    MTBE 3494.38
    2-butoxyethanol 1166.61
    propionic acid 1086.64
    o-xylene 802.07
    formic acid 114.96
    diethyl ether 3391.79
    m-xylene 872.76
    p-xylene 1075.25
    chlorobenzene 2252.47
    dimethyl carbonate 644.28
    n-octane 85.83
    formamide 301.05
    cyclopentanone 5260.48
    2-pentanone 3880.68
    anisole 1604.27
    cyclopentyl methyl ether 3360.4
    gamma-butyrolactone 4658.59
    1-methoxy-2-propanol 1902.04
    pyridine 3540.47
    3-pentanone 2474.19
    furfural 2865.02
    n-dodecane 56.22
    diethylene glycol 520.73
    diisopropyl ether 1162.86
    tert-amyl alcohol 1717.15
    acetylacetone 3472.98
    n-hexadecane 71.81
    acetophenone 1556.27
    methyl propionate 2387.55
    isopentyl acetate 2907.57
    trichloroethylene 7160.55
    n-nonanol 483.63
    cyclohexanol 2024.93
    benzyl alcohol 905.93
    2-ethylhexanol 761.96
    isooctanol 537.73
    dipropyl ether 1627.15
    1,2-dichlorobenzene 2130.12
    ethyl lactate 758.02
    propylene carbonate 2689.34
    n-methylformamide 1081.14
    2-pentanol 1375.28
    n-pentane 267.51
    1-propoxy-2-propanol 1534.8
    1-methoxy-2-propyl acetate 2321.87
    2-(2-methoxypropoxy) propanol 935.57
    mesitylene 643.82
    ε-caprolactone 4719.26
    p-cymene 458.52
    epichlorohydrin 5265.55
    1,1,1-trichloroethane 5336.42
    2-aminoethanol 266.34
    morpholine-4-carbaldehyde 2635.77
    sulfolane 4238.45
    2,2,4-trimethylpentane 152.88
    2-methyltetrahydrofuran 4996.44
    n-hexyl acetate 2383.73
    isooctane 125.36
    2-(2-butoxyethoxy)ethanol 1364.99
    sec-butyl acetate 2606.23
    tert-butyl acetate 3310.89
    decalin 315.66
    glycerin 216.66
    diglyme 3153.68
    acrylic acid 574.93
    isopropyl myristate 754.64
    n-butyric acid 2900.5
    acetyl acetate 2157.69
    di(2-ethylhexyl) phthalate 491.52
    ethyl propionate 2831.36
    nitromethane 2435.19
    1,2-diethoxyethane 2823.33
    benzonitrile 1687.9
    trioctyl phosphate 372.12
    1-bromopropane 3291.33
    gamma-valerolactone 5578.88
    n-decanol 316.48
    triethyl phosphate 750.79
    4-methyl-2-pentanol 816.5
    propionitrile 2161.41
    vinylene carbonate 2031.2
    1,1,2-trichlorotrifluoroethane 2312.62
    DMS 1357.48
    cumene 496.06
    2-octanol 495.35
    2-hexanone 2672.4
    octyl acetate 859.15
    limonene 814.8
    1,2-dimethoxyethane 3657.43
    ethyl orthosilicate 736.89
    tributyl phosphate 536.68
    diacetone alcohol 2042.51
    N,N-dimethylaniline 880.94
    acrylonitrile 1836.01
    aniline 1353.54
    1,3-propanediol 674.19
    bromobenzene 2747.48
    dibromomethane 4650.42
    1,1,2,2-tetrachloroethane 6012.71
    2-methyl-cyclohexyl acetate 1427.23
    tetrabutyl urea 688.0
    diisobutyl methanol 522.04
    2-phenylethanol 863.01
    styrene 1027.8
    dioctyl adipate 1006.03
    dimethyl sulfate 975.73
    ethyl butyrate 2478.08
    methyl lactate 621.73
    butyl lactate 1200.86
    diethyl carbonate 1298.71
    propanediol butyl ether 799.85
    triethyl orthoformate 1473.77
    p-tert-butyltoluene 431.38
    methyl 4-tert-butylbenzoate 1190.35
    morpholine 4217.38
    tert-butylamine 1414.81
    n-dodecanol 230.24
    dimethoxymethane 2000.61
    ethylene carbonate 2199.97
    cyrene 779.7
    2-ethoxyethyl acetate 2454.65
    2-ethylhexyl acetate 2228.16
    1,2,4-trichlorobenzene 2308.6
    4-methylpyridine 3419.96
    dibutyl ether 1677.78
    2,6-dimethyl-4-heptanol 522.04
    DEF 3648.48
    dimethyl isosorbide 1766.69
    tetrachloroethylene 3742.85
    eugenol 924.39
    triacetin 1734.68
    span 80 864.48
    1,4-butanediol 255.03
    1,1-dichloroethane 5386.28
    2-methyl-1-pentanol 969.44
    methyl formate 699.19
    2-methyl-1-butanol 1387.34
    n-decane 119.39
    butyronitrile 2625.37
    3,7-dimethyl-1-octanol 675.34
    1-chlorooctane 652.9
    1-chlorotetradecane 204.56
    n-nonane 119.96
    undecane 76.6
    tert-butylcyclohexane 244.09
    cyclooctane 244.35
    cyclopentanol 1899.75
    tetrahydropyran 5340.88
    tert-amyl methyl ether 2065.75
    2,5,8-trioxanonane 1603.83
    1-hexene 1280.04
    2-isopropoxyethanol 1253.3
    2,2,2-trifluoroethanol 331.79
    methyl butyrate 4040.04

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction