3-(Cyclohexyloxy)propane-1,2-diol

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  • Identifiers

    CAS number
    10305-41-6

    Molecular formula
    C9H18O3

    SMILES
    C1CCC(CC1)OCC(CO)O

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Fruity 65.18%
    Alcoholic 33.07%
    Odorless 32.95%
    Oily 31.7%
    Mint 29.55%
    Ethereal 28.61%
    Fermented 27.18%
    Fresh 26.7%
    Sweet 26.14%
    Solvent 24.53%

     

    Flavor
    Sweet 50.59%
    Odorless 43.1%
    Sweet-like 26.08%
    Fatty 25.57%
    Cauliflower 24.08%
    Very slight 23.26%
    Fruit 22.85%
    Oily 22.77%
    Alkaline 21.52%
    Musty 21.39%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.6

    pKa est.
    6.9 (neutral)

    Molecular weight
    174.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    283°C

    Flash point

    • 145.06 ˚C est.

  • Synonyms

    • 3-(cyclohexyloxy)propane-1,2-diol
    • RefChem:494754
    • 805-622-3
    • Cyclohexylglycerin
    • 10305-41-6
    • 3-cyclohexyloxypropane-1,2-diol
    • 1-Cyclohexyl glycerol ether
    • 1,2-Propanediol, 3-(cyclohexyloxy)-
    • 1,2-Propanediol, 3- (cyclohexyloxy)-
    • UL93J4379X
    • NSC-26621
    • UNII-UL93J4379X
    • NSC26621
    • 1,2-Propanediol, 3-cyclohexyloxy-
    • NSC 26621
    • BRN 1853520
    • ADEKA NOL CHG
    • 1, 3-(cyclohexyloxy)-
    • 1-CYCLOHEXYLGLYCERIN
    • 1-CYCLOHEXYLGLYCEROL
    • EC 805-622-3
    • WLN: L6TJ AOY1Q1Q
    • SCHEMBL3815044
    • SCHEMBL4262966
    • SCHEMBL4537252
    • SCHEMBL5236303
    • DTXSID70893623
    • (+/-)-CYCLOHEXYLGLYCERIN
    • OWTXHZITCDRRTI-UHFFFAOYSA-N
    • AKOS006280148
    • GLYCEROL .ALPHA.-MONOCYCLOHEXYL ETHER
    • NS00008244
    • Q27291127
    • 10305-41-6

  • Applications

    3-(Cyclohexyloxy)propane-1,2-diol (CAS 10305-41-6) is used as a diol building block in polymer formulations, notably as a chain extender or flexible segment in polyurethane and polyester resins; it can serve as a reactive diluent or modifier in coatings, inks, and adhesives to adjust viscosity and performance; it may act as a crosslinking or curing component in epoxy- and polyurethane-based systems; it is also employed as an intermediate in chemical synthesis to access specialty polyols and related polymers; and in industrial formulations it may function as a solvent or co-solvent where diol functionality is desired.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 882.03
    methanol 1497.14
    isopropanol 546.67
    water 7.41
    ethyl acetate 204.82
    n-propanol 657.05
    acetone 259.29
    n-butanol 566.07
    acetonitrile 135.89
    DMF 389.4
    toluene 30.48
    isobutanol 382.3
    1,4-dioxane 369.51
    methyl acetate 132.65
    THF 633.7
    2-butanone 149.03
    n-pentanol 239.46
    sec-butanol 327.24
    n-hexane 8.62
    ethylene glycol 353.68
    NMP 264.52
    cyclohexane 29.08
    DMSO 1458.3
    n-butyl acetate 156.95
    n-octanol 71.16
    chloroform 272.15
    n-propyl acetate 142.44
    acetic acid 806.35
    dichloromethane 251.16
    cyclohexanone 343.57
    propylene glycol 420.21
    isopropyl acetate 124.1
    DMAc 193.93
    2-ethoxyethanol 458.95
    isopentanol 360.07
    n-heptane 13.08
    ethyl formate 222.14
    1,2-dichloroethane 185.51
    n-hexanol 221.54
    2-methoxyethanol 1009.51
    isobutyl acetate 83.99
    tetrachloromethane 48.07
    n-pentyl acetate 78.5
    transcutol 990.76
    n-heptanol 92.38
    ethylbenzene 22.51
    MIBK 112.63
    2-propoxyethanol 357.52
    tert-butanol 544.79
    MTBE 131.38
    2-butoxyethanol 215.79
    propionic acid 417.49
    o-xylene 34.04
    formic acid 475.2
    diethyl ether 107.5
    m-xylene 34.37
    p-xylene 32.03
    chlorobenzene 72.86
    dimethyl carbonate 55.82
    n-octane 4.92
    formamide 532.24
    cyclopentanone 394.99
    2-pentanone 173.77
    anisole 71.47
    cyclopentyl methyl ether 210.0
    gamma-butyrolactone 531.1
    1-methoxy-2-propanol 619.21
    pyridine 200.22
    3-pentanone 80.45
    furfural 458.33
    n-dodecane 3.93
    diethylene glycol 411.29
    diisopropyl ether 36.67
    tert-amyl alcohol 286.54
    acetylacetone 206.32
    n-hexadecane 4.4
    acetophenone 96.44
    methyl propionate 136.87
    isopentyl acetate 137.96
    trichloroethylene 357.66
    n-nonanol 60.83
    cyclohexanol 319.08
    benzyl alcohol 124.42
    2-ethylhexanol 105.18
    isooctanol 76.6
    dipropyl ether 89.54
    1,2-dichlorobenzene 78.94
    ethyl lactate 112.83
    propylene carbonate 295.31
    n-methylformamide 403.62
    2-pentanol 238.1
    n-pentane 10.44
    1-propoxy-2-propanol 262.63
    1-methoxy-2-propyl acetate 158.57
    2-(2-methoxypropoxy) propanol 163.73
    mesitylene 28.84
    ε-caprolactone 305.4
    p-cymene 29.71
    epichlorohydrin 426.46
    1,1,1-trichloroethane 115.69
    2-aminoethanol 595.1
    morpholine-4-carbaldehyde 349.0
    sulfolane 657.53
    2,2,4-trimethylpentane 9.15
    2-methyltetrahydrofuran 314.71
    n-hexyl acetate 101.1
    isooctane 8.31
    2-(2-butoxyethoxy)ethanol 255.94
    sec-butyl acetate 82.81
    tert-butyl acetate 132.81
    decalin 11.66
    glycerin 544.62
    diglyme 465.56
    acrylic acid 344.17
    isopropyl myristate 39.5
    n-butyric acid 669.37
    acetyl acetate 133.32
    di(2-ethylhexyl) phthalate 53.79
    ethyl propionate 94.42
    nitromethane 712.3
    1,2-diethoxyethane 153.77
    benzonitrile 111.96
    trioctyl phosphate 45.2
    1-bromopropane 70.5
    gamma-valerolactone 514.24
    n-decanol 44.3
    triethyl phosphate 60.59
    4-methyl-2-pentanol 118.46
    propionitrile 138.38
    vinylene carbonate 233.45
    1,1,2-trichlorotrifluoroethane 484.93
    DMS 77.01
    cumene 22.22
    2-octanol 48.69
    2-hexanone 99.84
    octyl acetate 51.69
    limonene 49.18
    1,2-dimethoxyethane 404.81
    ethyl orthosilicate 61.34
    tributyl phosphate 54.29
    diacetone alcohol 228.09
    N,N-dimethylaniline 54.02
    acrylonitrile 190.56
    aniline 119.82
    1,3-propanediol 821.75
    bromobenzene 58.26
    dibromomethane 143.81
    1,1,2,2-tetrachloroethane 314.26
    2-methyl-cyclohexyl acetate 96.81
    tetrabutyl urea 64.9
    diisobutyl methanol 65.13
    2-phenylethanol 109.26
    styrene 29.11
    dioctyl adipate 77.24
    dimethyl sulfate 115.69
    ethyl butyrate 119.8
    methyl lactate 155.71
    butyl lactate 117.26
    diethyl carbonate 75.13
    propanediol butyl ether 229.57
    triethyl orthoformate 93.78
    p-tert-butyltoluene 30.19
    methyl 4-tert-butylbenzoate 111.03
    morpholine 534.17
    tert-butylamine 238.37
    n-dodecanol 32.62
    dimethoxymethane 218.66
    ethylene carbonate 211.88
    cyrene 156.26
    2-ethoxyethyl acetate 114.64
    2-ethylhexyl acetate 90.18
    1,2,4-trichlorobenzene 96.47
    4-methylpyridine 130.89
    dibutyl ether 58.06
    2,6-dimethyl-4-heptanol 65.13
    DEF 199.03
    dimethyl isosorbide 231.67
    tetrachloroethylene 255.03
    eugenol 113.85
    triacetin 138.46
    span 80 160.5
    1,4-butanediol 249.45
    1,1-dichloroethane 115.06
    2-methyl-1-pentanol 153.66
    methyl formate 254.81
    2-methyl-1-butanol 294.91
    n-decane 6.34
    butyronitrile 185.15
    3,7-dimethyl-1-octanol 77.82
    1-chlorooctane 26.86
    1-chlorotetradecane 11.05
    n-nonane 6.11
    undecane 4.69
    tert-butylcyclohexane 10.4
    cyclooctane 10.24
    cyclopentanol 380.58
    tetrahydropyran 315.8
    tert-amyl methyl ether 87.47
    2,5,8-trioxanonane 305.28
    1-hexene 31.1
    2-isopropoxyethanol 238.7
    2,2,2-trifluoroethanol 252.93
    methyl butyrate 171.11

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction