3-Amino-1,2-propanediol

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  • Identifiers

    CAS number
    616-30-8

    Molecular formula
    C3H9NO2

    SMILES
    C(C(CO)O)N

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Odorless 67.27%
    Fishy 49.53%
    Sweet 24.59%
    Alcoholic 21.82%
    Ripe 18.79%
    Cheesy 16.32%
    Savory 15.39%
    Oily 14.94%
    Cooling 12.94%
    Animal 12.7%

     

    Flavor
    Odorless 72.85%
    Sweet 39.98%
    Sweet-like 28.7%
    Very slight 23.34%
    Mild 22.54%
    Cauliflower 20.56%
    Sulfurous 20.42%
    Soup 20.15%
    Alcoholic 19.73%
    Soy 19.47%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -2.0

    pKa est.
    5.87 (weak acid)

    Molecular weight
    91.11 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    262°C

    Flash point

    • 139.03 ˚C est.

  • Synonyms

    • 3-Amino-1,2-propanediol
    • 616-30-8
    • 1-Aminoglycerol
    • 1,2-Propanediol, 3-amino-
    • 2,3-Dihydroxypropylamine
    • 1-Aminopropanediol
    • RH369P864X
    • NSC-67381
    • DTXSID30862294
    • RefChem:92848
    • DTXCID90811081
    • 210-475-8
    • Aminopropanediol
    • 3-Aminopropane-1,2-diol
    • 1-Amino-2,3-propanediol
    • 2,3-Propandiol-1-amine
    • 3-Amino-1,2-propandiol
    • (+/-)-3-Amino-1,2-propanediol
    • 3-aminopropan-1,2-diol
    • isoserinol
    • MFCD00008140
    • C3H9NO2
    • 1-Amino-2,3-dihydroxypropane
    • (RS)-3-amino-1,2-propanediol
    • ( inverted exclamation markA)-3-Amino-1,2-propanediol
    • EINECS 210-475-8
    • NSC 67381
    • BRN 1719121
    • UNII-RH369P864X
    • AI3-11002
    • Aminopropylene glycol
    • aminopropan-2,3-diol
    • amino-2,3-propanediol
    • 3-amino-l,2-propandiol
    • 3-amino1,2-propanediol
    • (+/-)-3-Amino-1,2-propanediol, 97%
    • 1-amino-2,3-propandiol
    • 1-aminopropane-2,3-diol
    • 2,3-dihydroxy-propylamine
    • 3-amino-2-hydroxypropanol
    • EC 210-475-8
    • 3-amino-propan-1,2-diol
    • WLN: Z1YQ1Q
    • 1-amino-2,3-propane diol
    • 3-amino propane 1,2-diol
    • 3-amino-1,2-propane-diol
    • 3-amino-propane-1,2-diol
    • SCHEMBL33836
    • 2,3-dihydroxy-1-propylamine
    • 4-04-00-01865 (Beilstein Handbook Reference)
    • SCHEMBL360198
    • SCHEMBL475104
    • 3-Amino-1,2-dihydroxypropane
    • orb2944111
    • SCHEMBL2726349
    • SCHEMBL5786319
    • SCHEMBL6546063
    • SCHEMBL7900420
    • SCHEMBL8664561
    • (RS)-3-amino-1,2-propandiol
    • racemic 1-amino-2,3-propanediol
    • racemic 3-amino-1,2-propanediol
    • racemic 3-aminopropane-1,2-diol
    • racemic-3-amino-1,2-propanediol
    • N-(2,3-dihydroxy-propyl)-amine
    • (+/-)3-amino-1,2-propanediol
    • (2rs)-3-amino-1,2-propanediol
    • (R/S)-3-aminopropane-1,2-diol
    • (+/-)-3-Amino-1,2-propandiol
    • NSC67381
    • STR01210
    • (+/-) 3-amino-1,2-propanediol
    • (+/-)-3-aminopropane-1,2-diol
    • CL4509
    • (A+/-)-3-Amino-1,2-propanediol
    • AKOS005259373
    • CS-W002040
    • EBC-267074
    • SB44645
    • SB44646
    • AC-23129
    • BP-12973
    • DB-018078
    • A0628
    • NS00007607
    • EN300-50845
    • (+/-)-3-AMINO-1,2-DIHYDROXYPROPANE
    • F093744
    • Q27288116
    • AB258BA4-8B6E-4939-A773-6152376CFD23
    • 616-30-8

  • Applications

    3-Amino-1,2-propanediol (CAS 616-30-8) is a bifunctional building block frequently used in polymer and resin chemistry. It can function as a curing agent or crosslinker for epoxy resin systems and as a chain extender or functional comonomer in polyurethane and polyurea formulations, contributing to adhesion, flexibility, and hydrophilicity. It is also employed as an intermediate in the synthesis of various polymers, specialty resins, and coatings, enabling the introduction of amino and hydroxyl functionalities into the polymer chain. Additionally, it serves as a precursor for pharmaceutical and agrochemical intermediates and, in some cases, is used to develop cosmetic ingredient formulations. Its applications depend on formulation requirements and local regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 6.18
    methanol 40.37
    isopropanol 1.31
    water 3341.38
    ethyl acetate 0.82
    n-propanol 4.12
    acetone 1.91
    n-butanol 2.21
    acetonitrile 2.53
    DMF 34.45
    toluene 0.14
    isobutanol 1.98
    1,4-dioxane 2.22
    methyl acetate 1.01
    THF 3.59
    2-butanone 1.14
    n-pentanol 0.96
    sec-butanol 1.55
    n-hexane 0.08
    ethylene glycol 146.82
    NMP 80.7
    cyclohexane 0.32
    DMSO 75.4
    n-butyl acetate 0.87
    n-octanol 0.59
    chloroform 0.4
    n-propyl acetate 0.54
    acetic acid 147.21
    dichloromethane 0.49
    cyclohexanone 3.8
    propylene glycol 46.99
    isopropyl acetate 0.45
    DMAc 24.98
    2-ethoxyethanol 9.52
    isopentanol 1.21
    n-heptane 0.33
    ethyl formate 2.54
    1,2-dichloroethane 0.41
    n-hexanol 1.58
    2-methoxyethanol 27.98
    isobutyl acetate 0.34
    tetrachloromethane 0.48
    n-pentyl acetate 0.61
    transcutol 12.64
    n-heptanol 1.28
    ethylbenzene 0.07
    MIBK 0.58
    2-propoxyethanol 8.45
    tert-butanol 1.55
    MTBE 0.32
    2-butoxyethanol 5.83
    propionic acid 21.15
    o-xylene 0.28
    formic acid 1058.14
    diethyl ether 0.34
    m-xylene 0.21
    p-xylene 0.14
    chlorobenzene 0.2
    dimethyl carbonate 1.46
    n-octane 0.11
    formamide 364.5
    cyclopentanone 6.41
    2-pentanone 0.87
    anisole 0.26
    cyclopentyl methyl ether 1.69
    gamma-butyrolactone 11.51
    1-methoxy-2-propanol 8.61
    pyridine 1.64
    3-pentanone 0.92
    furfural 16.61
    n-dodecane 0.05
    diethylene glycol 31.19
    diisopropyl ether 0.17
    tert-amyl alcohol 1.95
    acetylacetone 1.84
    n-hexadecane 0.05
    acetophenone 0.73
    methyl propionate 1.56
    isopentyl acetate 0.64
    trichloroethylene 0.81
    n-nonanol 0.55
    cyclohexanol 2.99
    benzyl alcohol 1.08
    2-ethylhexanol 0.89
    isooctanol 0.88
    dipropyl ether 0.75
    1,2-dichlorobenzene 0.25
    ethyl lactate 2.4
    propylene carbonate 4.05
    n-methylformamide 38.85
    2-pentanol 0.8
    n-pentane 0.11
    1-propoxy-2-propanol 4.82
    1-methoxy-2-propyl acetate 1.74
    2-(2-methoxypropoxy) propanol 4.04
    mesitylene 0.22
    ε-caprolactone 4.63
    p-cymene 0.3
    epichlorohydrin 2.4
    1,1,1-trichloroethane 0.23
    2-aminoethanol 84.59
    morpholine-4-carbaldehyde 33.96
    sulfolane 45.36
    2,2,4-trimethylpentane 0.09
    2-methyltetrahydrofuran 1.96
    n-hexyl acetate 0.64
    isooctane 0.06
    2-(2-butoxyethoxy)ethanol 5.92
    sec-butyl acetate 0.29
    tert-butyl acetate 0.65
    decalin 0.09
    glycerin 185.59
    diglyme 9.05
    acrylic acid 42.7
    isopropyl myristate 0.25
    n-butyric acid 10.88
    acetyl acetate 1.07
    di(2-ethylhexyl) phthalate 0.9
    ethyl propionate 0.49
    nitromethane 41.51
    1,2-diethoxyethane 0.74
    benzonitrile 0.65
    trioctyl phosphate 0.73
    1-bromopropane 0.15
    gamma-valerolactone 16.16
    n-decanol 0.4
    triethyl phosphate 0.98
    4-methyl-2-pentanol 0.5
    propionitrile 1.17
    vinylene carbonate 3.87
    1,1,2-trichlorotrifluoroethane 25.64
    DMS 0.83
    cumene 0.11
    2-octanol 0.5
    2-hexanone 0.41
    octyl acetate 0.43
    limonene 0.49
    1,2-dimethoxyethane 3.33
    ethyl orthosilicate 0.94
    tributyl phosphate 0.8
    diacetone alcohol 3.31
    N,N-dimethylaniline 0.48
    acrylonitrile 2.56
    aniline 1.18
    1,3-propanediol 36.45
    bromobenzene 0.12
    dibromomethane 0.29
    1,1,2,2-tetrachloroethane 0.73
    2-methyl-cyclohexyl acetate 0.85
    tetrabutyl urea 1.39
    diisobutyl methanol 0.58
    2-phenylethanol 1.12
    styrene 0.09
    dioctyl adipate 0.63
    dimethyl sulfate 6.25
    ethyl butyrate 0.95
    methyl lactate 8.1
    butyl lactate 2.38
    diethyl carbonate 0.54
    propanediol butyl ether 7.53
    triethyl orthoformate 1.06
    p-tert-butyltoluene 0.3
    methyl 4-tert-butylbenzoate 1.97
    morpholine 4.67
    tert-butylamine 0.64
    n-dodecanol 0.31
    dimethoxymethane 3.52
    ethylene carbonate 2.77
    cyrene 11.04
    2-ethoxyethyl acetate 1.02
    2-ethylhexyl acetate 0.54
    1,2,4-trichlorobenzene 0.38
    4-methylpyridine 0.91
    dibutyl ether 0.28
    2,6-dimethyl-4-heptanol 0.58
    DEF 4.25
    dimethyl isosorbide 6.66
    tetrachloroethylene 1.42
    eugenol 3.29
    triacetin 1.59
    span 80 5.67
    1,4-butanediol 13.78
    1,1-dichloroethane 0.16
    2-methyl-1-pentanol 0.71
    methyl formate 16.62
    2-methyl-1-butanol 1.74
    n-decane 0.08
    butyronitrile 0.84
    3,7-dimethyl-1-octanol 0.49
    1-chlorooctane 0.13
    1-chlorotetradecane 0.07
    n-nonane 0.08
    undecane 0.06
    tert-butylcyclohexane 0.06
    cyclooctane 0.17
    cyclopentanol 6.6
    tetrahydropyran 1.01
    tert-amyl methyl ether 0.45
    2,5,8-trioxanonane 7.85
    1-hexene 0.11
    2-isopropoxyethanol 3.2
    2,2,2-trifluoroethanol 96.74
    methyl butyrate 0.92

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction