3-(4-Hydroxyphenyl)propanol

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  • Identifiers

    CAS number
    10210-17-0

    Molecular formula
    C9H12O2

    SMILES
    C1=CC(=CC=C1CCCO)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 78.9%
    Floral 73.86%
    Fruity 60.81%
    Rose 50.71%
    Balsamic 48.71%
    Phenolic 43.21%
    Honey 35.05%
    Vanilla 34.63%
    Spicy 32.96%
    Powdery 32.53%

     

    Flavor
    Sweet 89.17%
    Fruity 58.11%
    Floral 56.76%
    Spicy 45.99%
    Powdery 41.54%
    Mild 40.6%
    Balsam 40.1%
    Phenolic 38.99%
    Vanilla 37.24%
    Bitter 34.36%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.3

    pKa est.
    9.92 (weak base)

    Molecular weight
    152.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    313°C

    Melting point expt.

    • 55 °C

    Flash point

    • 155.98 ˚C est.

  • Synonyms

    • HPP cpd
    • 3-(4-hydroxyphenyl)propanol
    • RefChem:493146
    • 3-(4-Hydroxyphenyl)-1-propanol
    • 10210-17-0
    • 4-(3-Hydroxypropyl)phenol
    • Benzenepropanol, 4-hydroxy-
    • 3-(4-Hydroxyphenyl)propan-1-ol
    • MFCD00002953
    • Dihydro-p-coumaryl alcohol
    • 4-(3-hydroxy-propyl)-phenol
    • 3-(p-Hydroxyphenyl)-1-propanol
    • 4-hydroxybenzenepropanol
    • 4-Hydroxy-Benzenepropanol
    • 1DJM7P148S
    • 1-(4-Hydroxyphenyl)-3-propanol
    • 1-Propanol, 3-(p-hydroxyphenyl)-
    • Dihydro-p-coumaryl alcohol;3-(p-Hydroxyphenyl)propyl alcohol
    • UNII-1DJM7P148S
    • AI3-12108
    • EINECS 233-511-4
    • 4-g-Hydroxypropylphenol
    • p-Hydroxyphenyl-3-propanol
    • Dihydro-p-coumaroyl alcohol
    • 3-(p-Hydroxyphenyl)propanol
    • 4-(3-hydroxypropyl) phenol
    • SCHEMBL274830
    • 3-(4-Hydroxyphenyl)-propanol
    • 4-Hydroxybenzenepropanol, 9CI
    • orb1303821
    • SCHEMBL1043663
    • SCHEMBL4525373
    • 3-(4hydroxyphenyl)-1-propanol
    • 3-(p-Hydroxyphenyl)propan-1-ol
    • DTXSID80144638
    • CHEBI:179258
    • 3-(4-hydroxyphenyl) propan-1-ol
    • HY-N1753
    • s5835
    • AKOS005217781
    • CS-W008850
    • EBC-153118
    • FD10610
    • SB30222
    • 3-(4-Hydroxyphenyl)-1-propanol, 99%
    • 3-(P-HYDROXYPHENYL)PROPYL ALCOHOL
    • DS-11902
    • FH146214
    • SY101960
    • NS00023110
    • ST51038042
    • EN300-101014
    • F209107
    • Q27252283
    • Z1255485203
    • InChI=1/C9H12O2/c10-7-1-2-8-3-5-9(11)6-4-8/h3-6,10-11H,1-2,7H
    • 10210-17-0

  • Applications

    Chemical name: 3-(4-Hydroxyphenyl)propanol; CAS 10210-17-0. It is principally used as an intermediate in fragrance chemistry and personal care formulations, serving as a building block for aroma compounds and as a scent precursor in perfumes and cosmetics. It is also evaluated as a diol component for polymer synthesis, offering two hydroxyl functionalities suitable for polyurethane and epoxy resin formulations. In household and cleaning products, it may be used as a fragrance ingredient or fragrance precursor to contribute to odor profiles. Additionally, it may be pursued as a specialty intermediate in coatings and inks, enabling crosslinking or resin modification, and it may be studied as a pharmaceutical synthetic intermediate under appropriate regulatory controls.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 382.07
    methanol 607.75
    isopropanol 238.75
    water 3.47
    ethyl acetate 507.1
    n-propanol 246.61
    acetone 438.15
    n-butanol 204.37
    acetonitrile 154.99
    DMF 537.44
    toluene 30.68
    isobutanol 190.09
    1,4-dioxane 415.61
    methyl acetate 338.01
    THF 619.35
    2-butanone 245.48
    n-pentanol 147.48
    sec-butanol 153.86
    n-hexane 1.2
    ethylene glycol 282.54
    NMP 237.93
    cyclohexane 1.85
    DMSO 738.86
    n-butyl acetate 213.95
    n-octanol 52.6
    chloroform 33.14
    n-propyl acetate 198.65
    acetic acid 594.78
    dichloromethane 41.12
    cyclohexanone 262.65
    propylene glycol 313.56
    isopropyl acetate 223.39
    DMAc 378.69
    2-ethoxyethanol 531.97
    isopentanol 220.93
    n-heptane 4.44
    ethyl formate 252.15
    1,2-dichloroethane 52.36
    n-hexanol 221.82
    2-methoxyethanol 986.88
    isobutyl acetate 106.89
    tetrachloromethane 11.83
    n-pentyl acetate 68.0
    transcutol 858.16
    n-heptanol 81.29
    ethylbenzene 16.83
    MIBK 182.27
    2-propoxyethanol 481.17
    tert-butanol 534.19
    MTBE 199.89
    2-butoxyethanol 189.92
    propionic acid 424.35
    o-xylene 26.86
    formic acid 414.84
    diethyl ether 78.0
    m-xylene 41.34
    p-xylene 20.94
    chlorobenzene 33.94
    dimethyl carbonate 135.22
    n-octane 2.07
    formamide 665.44
    cyclopentanone 462.66
    2-pentanone 299.21
    anisole 98.61
    cyclopentyl methyl ether 207.39
    gamma-butyrolactone 629.34
    1-methoxy-2-propanol 580.95
    pyridine 113.19
    3-pentanone 112.41
    furfural 324.57
    n-dodecane 2.42
    diethylene glycol 504.77
    diisopropyl ether 41.72
    tert-amyl alcohol 261.15
    acetylacetone 421.62
    n-hexadecane 2.65
    acetophenone 93.83
    methyl propionate 299.73
    isopentyl acetate 169.13
    trichloroethylene 146.12
    n-nonanol 47.2
    cyclohexanol 122.61
    benzyl alcohol 107.63
    2-ethylhexanol 91.06
    isooctanol 63.69
    dipropyl ether 91.37
    1,2-dichlorobenzene 36.13
    ethyl lactate 107.8
    propylene carbonate 264.52
    n-methylformamide 550.37
    2-pentanol 126.31
    n-pentane 1.05
    1-propoxy-2-propanol 280.14
    1-methoxy-2-propyl acetate 247.46
    2-(2-methoxypropoxy) propanol 161.39
    mesitylene 25.42
    ε-caprolactone 249.72
    p-cymene 21.24
    epichlorohydrin 495.72
    1,1,1-trichloroethane 59.12
    2-aminoethanol 482.43
    morpholine-4-carbaldehyde 410.76
    sulfolane 508.97
    2,2,4-trimethylpentane 3.33
    2-methyltetrahydrofuran 334.47
    n-hexyl acetate 89.39
    isooctane 4.61
    2-(2-butoxyethoxy)ethanol 240.49
    sec-butyl acetate 105.51
    tert-butyl acetate 224.38
    decalin 3.42
    glycerin 485.25
    diglyme 443.28
    acrylic acid 299.86
    isopropyl myristate 36.94
    n-butyric acid 517.78
    acetyl acetate 217.75
    di(2-ethylhexyl) phthalate 44.73
    ethyl propionate 145.61
    nitromethane 1007.82
    1,2-diethoxyethane 187.26
    benzonitrile 80.71
    trioctyl phosphate 37.13
    1-bromopropane 14.83
    gamma-valerolactone 568.61
    n-decanol 37.92
    triethyl phosphate 52.52
    4-methyl-2-pentanol 94.1
    propionitrile 108.44
    vinylene carbonate 187.24
    1,1,2-trichlorotrifluoroethane 335.48
    DMS 94.45
    cumene 17.02
    2-octanol 39.74
    2-hexanone 153.73
    octyl acetate 48.6
    limonene 32.36
    1,2-dimethoxyethane 506.64
    ethyl orthosilicate 51.61
    tributyl phosphate 43.12
    diacetone alcohol 364.54
    N,N-dimethylaniline 59.72
    acrylonitrile 184.57
    aniline 84.23
    1,3-propanediol 558.49
    bromobenzene 26.47
    dibromomethane 18.4
    1,1,2,2-tetrachloroethane 99.34
    2-methyl-cyclohexyl acetate 81.95
    tetrabutyl urea 60.79
    diisobutyl methanol 57.73
    2-phenylethanol 113.21
    styrene 18.42
    dioctyl adipate 60.71
    dimethyl sulfate 193.41
    ethyl butyrate 132.05
    methyl lactate 181.06
    butyl lactate 82.1
    diethyl carbonate 80.7
    propanediol butyl ether 169.48
    triethyl orthoformate 80.86
    p-tert-butyltoluene 22.77
    methyl 4-tert-butylbenzoate 94.48
    morpholine 550.68
    tert-butylamine 154.72
    n-dodecanol 29.91
    dimethoxymethane 450.98
    ethylene carbonate 175.35
    cyrene 138.98
    2-ethoxyethyl acetate 134.92
    2-ethylhexyl acetate 100.3
    1,2,4-trichlorobenzene 50.72
    4-methylpyridine 123.04
    dibutyl ether 45.41
    2,6-dimethyl-4-heptanol 57.73
    DEF 248.37
    dimethyl isosorbide 240.77
    tetrachloroethylene 74.14
    eugenol 109.36
    triacetin 111.56
    span 80 123.78
    1,4-butanediol 193.79
    1,1-dichloroethane 44.7
    2-methyl-1-pentanol 124.24
    methyl formate 401.07
    2-methyl-1-butanol 164.75
    n-decane 3.29
    butyronitrile 130.03
    3,7-dimethyl-1-octanol 59.24
    1-chlorooctane 16.68
    1-chlorotetradecane 8.33
    n-nonane 2.8
    undecane 2.77
    tert-butylcyclohexane 4.81
    cyclooctane 1.5
    cyclopentanol 195.52
    tetrahydropyran 164.12
    tert-amyl methyl ether 112.39
    2,5,8-trioxanonane 286.15
    1-hexene 9.94
    2-isopropoxyethanol 295.66
    2,2,2-trifluoroethanol 175.07
    methyl butyrate 206.32

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction