3-(3,4-Dihydroxyphenyl)lactate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    23028-17-3

    Molecular formula
    C9H9O5-

    SMILES
    C1=CC(=C(C=C1CC(C(=O)[O-])O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 71.82%
    Vanilla 32.19%
    Phenolic 28.0%
    Sweet 27.61%
    Milky 25.17%
    Burnt 23.11%
    Balsamic 22.79%
    Savory 22.2%
    Creamy 21.87%
    Bitter 20.91%

     

    Flavor
    Odorless 59.42%
    Bitter 40.12%
    Mild 36.65%
    Bland 29.29%
    Very mild 27.83%
    Sweet-like 24.91%
    Yeast 19.81%
    Orange flower 19.63%
    Faint 19.43%
    Cadaverous 19.38%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.4

    pKa est.
    6.1 (neutral)

    Molecular weight
    197.16 g/mol

    Flash point

    • 210.14 ˚C est.

  • Synonyms

    • 3-(3,4-Dihydroxyphenyl)lactate
    • 3-(3,4-dihydroxyphenyl)-2-hydroxypropanoate
    • CHEBI:58279
    • 3-(3,4-dihydroxyphenyl)lactate anion
    • 3-(3,4-dihydroxyphenyl)lactate(1-)
    • 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid
    • RefChem:92262
    • 23028-17-3
    • NCGC00346605-01
    • NCGC00346605-06
    • Q27125666
    • 23028-17-3

  • Applications

    3-(3,4-Dihydroxyphenyl)lactate (CAS 23028-17-3) is used as a building block for bio-based polymers and functional polymers incorporating catechol groups, enabling modification of poly(lactic acid) derivatives. In coatings and adhesives, the compound can function as a catechol-based adhesion promoter or crosslinking agent, improving surface bonding in coatings, inks, and adhesives. Its catechol moiety also supports antioxidant and stabilizing roles as an additive for polymers, coatings, and cosmetics. It may serve as a chiral intermediate in pharmaceutical synthesis. It can also be evaluated as a fragrance intermediate or aroma-chemistry precursor.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 74.07
    methanol 162.88
    isopropanol 34.37
    water 35.22
    ethyl acetate 14.42
    n-propanol 25.52
    acetone 85.54
    n-butanol 16.49
    acetonitrile 5.76
    DMF 139.09
    toluene 3.95
    isobutanol 10.17
    1,4-dioxane 32.51
    methyl acetate 13.33
    THF 79.83
    2-butanone 21.21
    n-pentanol 9.61
    sec-butanol 18.92
    n-hexane 0.39
    ethylene glycol 181.16
    NMP 131.45
    cyclohexane 0.79
    DMSO 330.63
    n-butyl acetate 5.53
    n-octanol 10.11
    chloroform 0.18
    n-propyl acetate 4.97
    acetic acid 39.69
    dichloromethane 0.5
    cyclohexanone 14.05
    propylene glycol 63.47
    isopropyl acetate 10.93
    DMAc 184.27
    2-ethoxyethanol 145.13
    isopentanol 18.06
    n-heptane 1.83
    ethyl formate 10.23
    1,2-dichloroethane 1.52
    n-hexanol 16.18
    2-methoxyethanol 286.36
    isobutyl acetate 1.08
    tetrachloromethane 0.35
    n-pentyl acetate 6.16
    transcutol 102.7
    n-heptanol 14.04
    ethylbenzene 2.35
    MIBK 15.66
    2-propoxyethanol 72.23
    tert-butanol 89.88
    MTBE 16.68
    2-butoxyethanol 41.09
    propionic acid 15.71
    o-xylene 6.17
    formic acid 234.63
    diethyl ether 12.51
    m-xylene 5.38
    p-xylene 1.95
    chlorobenzene 0.63
    dimethyl carbonate 17.45
    n-octane 0.9
    formamide 344.61
    cyclopentanone 32.0
    2-pentanone 27.46
    anisole 9.46
    cyclopentyl methyl ether 21.18
    gamma-butyrolactone 43.26
    1-methoxy-2-propanol 141.19
    pyridine 8.55
    3-pentanone 11.57
    furfural 28.17
    n-dodecane 0.59
    diethylene glycol 134.89
    diisopropyl ether 5.45
    tert-amyl alcohol 51.06
    acetylacetone 46.7
    n-hexadecane 0.62
    acetophenone 11.12
    methyl propionate 18.4
    isopentyl acetate 4.97
    trichloroethylene 1.63
    n-nonanol 10.17
    cyclohexanol 12.34
    benzyl alcohol 11.96
    2-ethylhexanol 7.58
    isooctanol 9.58
    dipropyl ether 9.59
    1,2-dichlorobenzene 0.95
    ethyl lactate 13.33
    propylene carbonate 9.56
    n-methylformamide 94.9
    2-pentanol 16.94
    n-pentane 0.58
    1-propoxy-2-propanol 41.47
    1-methoxy-2-propyl acetate 19.17
    2-(2-methoxypropoxy) propanol 39.16
    mesitylene 4.05
    ε-caprolactone 14.92
    p-cymene 3.79
    epichlorohydrin 24.95
    1,1,1-trichloroethane 0.75
    2-aminoethanol 141.6
    morpholine-4-carbaldehyde 99.0
    sulfolane 81.93
    2,2,4-trimethylpentane 0.54
    2-methyltetrahydrofuran 27.66
    n-hexyl acetate 8.26
    isooctane 0.52
    2-(2-butoxyethoxy)ethanol 60.74
    sec-butyl acetate 3.5
    tert-butyl acetate 19.9
    decalin 0.48
    glycerin 150.26
    diglyme 83.58
    acrylic acid 20.2
    isopropyl myristate 4.76
    n-butyric acid 13.33
    acetyl acetate 6.77
    di(2-ethylhexyl) phthalate 5.88
    ethyl propionate 7.07
    nitromethane 72.32
    1,2-diethoxyethane 14.79
    benzonitrile 2.52
    trioctyl phosphate 5.23
    1-bromopropane 0.65
    gamma-valerolactone 53.73
    n-decanol 8.38
    triethyl phosphate 5.12
    4-methyl-2-pentanol 11.09
    propionitrile 3.25
    vinylene carbonate 5.63
    1,1,2-trichlorotrifluoroethane 34.78
    DMS 7.81
    cumene 2.02
    2-octanol 7.6
    2-hexanone 6.73
    octyl acetate 7.19
    limonene 5.19
    1,2-dimethoxyethane 79.72
    ethyl orthosilicate 4.67
    tributyl phosphate 4.09
    diacetone alcohol 71.96
    N,N-dimethylaniline 9.91
    acrylonitrile 5.45
    aniline 7.58
    1,3-propanediol 116.98
    bromobenzene 0.48
    dibromomethane 0.31
    1,1,2,2-tetrachloroethane 1.99
    2-methyl-cyclohexyl acetate 5.09
    tetrabutyl urea 10.75
    diisobutyl methanol 7.35
    2-phenylethanol 13.23
    styrene 1.89
    dioctyl adipate 6.66
    dimethyl sulfate 39.65
    ethyl butyrate 5.8
    methyl lactate 39.98
    butyl lactate 9.9
    diethyl carbonate 3.41
    propanediol butyl ether 35.37
    triethyl orthoformate 5.29
    p-tert-butyltoluene 4.3
    methyl 4-tert-butylbenzoate 21.52
    morpholine 45.42
    tert-butylamine 21.45
    n-dodecanol 6.24
    dimethoxymethane 109.54
    ethylene carbonate 4.62
    cyrene 40.08
    2-ethoxyethyl acetate 12.94
    2-ethylhexyl acetate 2.99
    1,2,4-trichlorobenzene 1.43
    4-methylpyridine 7.79
    dibutyl ether 4.67
    2,6-dimethyl-4-heptanol 7.35
    DEF 38.13
    dimethyl isosorbide 47.09
    tetrachloroethylene 2.34
    eugenol 21.45
    triacetin 11.59
    span 80 24.58
    1,4-butanediol 46.99
    1,1-dichloroethane 0.64
    2-methyl-1-pentanol 9.3
    methyl formate 61.54
    2-methyl-1-butanol 13.5
    n-decane 0.89
    butyronitrile 2.84
    3,7-dimethyl-1-octanol 7.72
    1-chlorooctane 2.14
    1-chlorotetradecane 1.14
    n-nonane 0.87
    undecane 0.72
    tert-butylcyclohexane 0.41
    cyclooctane 0.77
    cyclopentanol 16.93
    tetrahydropyran 9.95
    tert-amyl methyl ether 19.0
    2,5,8-trioxanonane 74.49
    1-hexene 0.93
    2-isopropoxyethanol 54.83
    2,2,2-trifluoroethanol 24.73
    methyl butyrate 8.01

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction