3-(2-Methoxyethoxy)propyl-methyl-bis(trimethylsilyloxy)silane

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  • Identifiers

    CAS number
    27306-78-1

    Molecular formula
    C13H34O4Si3

    SMILES
    COCCOCCC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 35.09%
    Alcoholic 34.2%
    Green 28.48%
    Mint 27.32%
    Woody 25.69%
    Ethereal 24.23%
    Fresh 24.04%
    Cooling 22.87%
    Fruity 22.54%
    Floral 22.45%

     

    Flavor
    Green 46.91%
    Fruity 34.46%
    Earthy 29.96%
    Bitter 27.47%
    Mild 26.74%
    Tropical 26.68%
    Sweet 23.51%
    Oily 22.82%
    Rose acetate 22.31%
    Catty 21.9%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.42 (neutral)

    Molecular weight
    338.66 g/mol

    Flash point

    • 85.16 ˚C est.

  • Synonyms

    • 3-(2-methoxyethoxy)propyl-methyl-bis(trimethylsilyloxy)silane
    • RefChem:491129
    • 608-078-3
    • 27306-78-1
    • Silwet L 77
    • MFCD00285093
    • SCHEMBL577857
    • C13H34O4Si3
    • JQRXTVACLHSVTF-UHFFFAOYSA-N
    • 2-[Methoxy(polyethyleneoxy)propyl]heptamethyl-trisiloxane Tech grade 90%
    • 3-(3-(2-Methoxyethoxy)propyl)-1,1,1,3,5,5,5-heptamethyltrisiloxane
    • 877815-31-1
    • 27306-78-1

  • Applications

    3-(2-Methoxyethoxy)propyl-methyl-bis(trimethylsilyloxy)silane (CAS 27306-78-1) is a silane precursor bearing two trimethylsilyloxy groups and a 3-(2-methoxyethoxy)propyl moiety. It is commonly used as a silane coupling agent and as a precursor for coatings, adhesives and sol-gel derived organosilica networks to improve adhesion between oxide surfaces (such as silica, glass and metals) and polymers. It also serves as a surface-modifying agent to introduce polyether functionality in polymer formulations and as a reactive intermediate to build organosilica networks in sol-gel processes. Additionally, it may be used in sealants, coatings and plastic-ceramic composites to enhance interfacial bonding and network stability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 287.02
    methanol 369.41
    isopropanol 233.57
    water 3.82
    ethyl acetate 300.35
    n-propanol 303.7
    acetone 334.46
    n-butanol 250.6
    acetonitrile 156.16
    DMF 522.87
    toluene 318.18
    isobutanol 219.4
    1,4-dioxane 534.32
    methyl acetate 257.18
    THF 1192.8
    2-butanone 319.72
    n-pentanol 211.06
    sec-butanol 258.4
    n-hexane 93.72
    ethylene glycol 76.84
    NMP 823.17
    cyclohexane 251.06
    DMSO 576.77
    n-butyl acetate 290.81
    n-octanol 237.85
    chloroform 975.18
    n-propyl acetate 285.39
    acetic acid 285.84
    dichloromethane 805.63
    cyclohexanone 776.04
    propylene glycol 157.05
    isopropyl acetate 242.06
    DMAc 507.63
    2-ethoxyethanol 296.39
    isopentanol 188.73
    n-heptane 105.03
    ethyl formate 225.13
    1,2-dichloroethane 426.76
    n-hexanol 277.66
    2-methoxyethanol 422.72
    isobutyl acetate 225.92
    tetrachloromethane 181.28
    n-pentyl acetate 320.19
    transcutol 555.48
    n-heptanol 202.53
    ethylbenzene 155.15
    MIBK 219.54
    2-propoxyethanol 415.83
    tert-butanol 243.87
    MTBE 215.61
    2-butoxyethanol 278.41
    propionic acid 263.69
    o-xylene 187.72
    formic acid 121.48
    diethyl ether 310.12
    m-xylene 198.09
    p-xylene 185.86
    chlorobenzene 324.79
    dimethyl carbonate 148.08
    n-octane 49.16
    formamide 162.84
    cyclopentanone 804.66
    2-pentanone 313.2
    anisole 255.44
    cyclopentyl methyl ether 623.63
    gamma-butyrolactone 813.56
    1-methoxy-2-propanol 381.24
    pyridine 489.43
    3-pentanone 273.11
    furfural 620.3
    n-dodecane 32.83
    diethylene glycol 273.46
    diisopropyl ether 134.14
    tert-amyl alcohol 238.28
    acetylacetone 350.33
    n-hexadecane 36.96
    acetophenone 276.57
    methyl propionate 277.84
    isopentyl acetate 247.51
    trichloroethylene 701.86
    n-nonanol 210.5
    cyclohexanol 423.7
    benzyl alcohol 233.48
    2-ethylhexanol 195.14
    isooctanol 166.97
    dipropyl ether 281.86
    1,2-dichlorobenzene 291.58
    ethyl lactate 167.88
    propylene carbonate 474.52
    n-methylformamide 285.53
    2-pentanol 205.58
    n-pentane 101.53
    1-propoxy-2-propanol 325.87
    1-methoxy-2-propyl acetate 301.96
    2-(2-methoxypropoxy) propanol 230.18
    mesitylene 131.09
    ε-caprolactone 682.05
    p-cymene 127.6
    epichlorohydrin 621.72
    1,1,1-trichloroethane 400.07
    2-aminoethanol 182.0
    morpholine-4-carbaldehyde 649.65
    sulfolane 935.21
    2,2,4-trimethylpentane 46.12
    2-methyltetrahydrofuran 681.77
    n-hexyl acetate 393.99
    isooctane 30.59
    2-(2-butoxyethoxy)ethanol 318.53
    sec-butyl acetate 210.15
    tert-butyl acetate 261.4
    decalin 78.83
    glycerin 213.19
    diglyme 498.51
    acrylic acid 217.39
    isopropyl myristate 165.92
    n-butyric acid 335.68
    acetyl acetate 231.47
    di(2-ethylhexyl) phthalate 152.78
    ethyl propionate 230.75
    nitromethane 382.87
    1,2-diethoxyethane 272.13
    benzonitrile 262.95
    trioctyl phosphate 130.55
    1-bromopropane 339.75
    gamma-valerolactone 929.43
    n-decanol 149.95
    triethyl phosphate 147.74
    4-methyl-2-pentanol 124.34
    propionitrile 184.91
    vinylene carbonate 416.2
    1,1,2-trichlorotrifluoroethane 507.21
    DMS 221.83
    cumene 109.54
    2-octanol 180.92
    2-hexanone 272.65
    octyl acetate 213.62
    limonene 204.05
    1,2-dimethoxyethane 445.17
    ethyl orthosilicate 152.51
    tributyl phosphate 143.28
    diacetone alcohol 258.04
    N,N-dimethylaniline 203.6
    acrylonitrile 195.85
    aniline 287.28
    1,3-propanediol 211.18
    bromobenzene 342.86
    dibromomethane 609.15
    1,1,2,2-tetrachloroethane 660.31
    2-methyl-cyclohexyl acetate 281.44
    tetrabutyl urea 202.7
    diisobutyl methanol 118.93
    2-phenylethanol 247.06
    styrene 186.09
    dioctyl adipate 222.93
    dimethyl sulfate 243.77
    ethyl butyrate 258.13
    methyl lactate 195.05
    butyl lactate 243.81
    diethyl carbonate 168.68
    propanediol butyl ether 292.73
    triethyl orthoformate 219.16
    p-tert-butyltoluene 130.65
    methyl 4-tert-butylbenzoate 267.64
    morpholine 630.27
    tert-butylamine 181.79
    n-dodecanol 115.58
    dimethoxymethane 430.58
    ethylene carbonate 378.52
    cyrene 307.19
    2-ethoxyethyl acetate 330.14
    2-ethylhexyl acetate 243.7
    1,2,4-trichlorobenzene 363.32
    4-methylpyridine 458.01
    dibutyl ether 230.8
    2,6-dimethyl-4-heptanol 118.93
    DEF 355.0
    dimethyl isosorbide 439.39
    tetrachloroethylene 420.6
    eugenol 241.8
    triacetin 333.37
    span 80 307.98
    1,4-butanediol 118.53
    1,1-dichloroethane 387.7
    2-methyl-1-pentanol 172.3
    methyl formate 227.07
    2-methyl-1-butanol 214.78
    n-decane 66.0
    butyronitrile 204.41
    3,7-dimethyl-1-octanol 176.23
    1-chlorooctane 193.04
    1-chlorotetradecane 72.38
    n-nonane 66.31
    undecane 43.92
    tert-butylcyclohexane 64.27
    cyclooctane 97.06
    cyclopentanol 453.69
    tetrahydropyran 734.55
    tert-amyl methyl ether 228.79
    2,5,8-trioxanonane 357.87
    1-hexene 182.93
    2-isopropoxyethanol 224.6
    2,2,2-trifluoroethanol 142.59
    methyl butyrate 288.47

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction