(2R,3S,4S,5R)-2-(Hydroxymethyl)-6-(tetradecyloxy)tetrahydro-2H-pyran-3,4,5-triol

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  • Identifiers

    CAS number
    54549-26-7

    Molecular formula
    C20H40O6

    SMILES
    CCCCCCCCCCCCCCOC1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Waxy 44.68%
    Oily 40.36%
    Citrus 35.72%
    Fatty 35.29%
    Odorless 34.45%
    Sweet 33.46%
    Fresh 31.68%
    Fruity 26.52%
    Clean 24.17%
    Milky 23.17%

     

    Flavor
    Fatty 45.32%
    Waxy 44.58%
    Mild 33.82%
    Oily 32.98%
    Sweet 27.5%
    Odorless 27.08%
    Bland 26.87%
    Coconut 25.95%
    Creamy 24.59%
    Fat 24.3%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.6

    pKa est.
    6.37 (neutral)

    Molecular weight
    376.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    781°C

    Flash point

    • 209.02 ˚C est.

  • Synonyms

    • 54549-26-7
    • SCHEMBL182847
    • ORUDEUCNYHCHPB-QUIYGKKVSA-N
    • MFCD23160509
    • (2R,3S,4S,5R)-2-(Hydroxymethyl)-6-(tetradecyloxy)tetrahydro-2H-pyran-3,4,5-triol
    • SY445221
    • Q27264413
    • 54549-26-7

  • Applications

    Chemical name: (2R,3S,4S,5R)-2-(Hydroxymethyl)-6-(tetradecyloxy)tetrahydro-2H-pyran-3,4,5-triol; CAS number: 54549-26-7. This sugar-derived glycoside with a C14 alkyl chain functions as a non-ionic surfactant and emulsifier. Real-world applications include: use as surfactant and emulsifier in cosmetics and personal care; in household cleaning products for cleaning and foam stability; as a solubilizer for fragrance oils in perfumery; as an emulsifier and dispersant in industrial manufacturing to blend oil and water systems; as a wetting agent and dispersant in coatings and inks; and as a potential additive in polymers and plastics to improve processing and dispersion.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 38.83
    methanol 103.92
    isopropanol 23.32
    water 5.71
    ethyl acetate 49.41
    n-propanol 35.39
    acetone 74.03
    n-butanol 29.88
    acetonitrile 20.71
    DMF 152.73
    toluene 13.22
    isobutanol 26.57
    1,4-dioxane 86.38
    methyl acetate 41.31
    THF 181.61
    2-butanone 48.57
    n-pentanol 24.48
    sec-butanol 25.7
    n-hexane 1.51
    ethylene glycol 23.36
    NMP 317.2
    cyclohexane 10.39
    DMSO 687.89
    n-butyl acetate 40.52
    n-octanol 26.64
    chloroform 71.92
    n-propyl acetate 43.72
    acetic acid 186.51
    dichloromethane 83.67
    cyclohexanone 178.38
    propylene glycol 31.56
    isopropyl acetate 48.71
    DMAc 230.01
    2-ethoxyethanol 98.87
    isopentanol 32.33
    n-heptane 2.91
    ethyl formate 47.8
    1,2-dichloroethane 74.69
    n-hexanol 21.09
    2-methoxyethanol 138.06
    isobutyl acetate 29.15
    tetrachloromethane 22.53
    n-pentyl acetate 70.35
    transcutol 294.78
    n-heptanol 34.12
    ethylbenzene 9.98
    MIBK 42.21
    2-propoxyethanol 72.34
    tert-butanol 41.69
    MTBE 25.0
    2-butoxyethanol 104.66
    propionic acid 82.58
    o-xylene 18.04
    formic acid 129.94
    diethyl ether 16.32
    m-xylene 14.09
    p-xylene 13.89
    chlorobenzene 25.13
    dimethyl carbonate 42.93
    n-octane 2.17
    formamide 180.73
    cyclopentanone 212.08
    2-pentanone 48.25
    anisole 22.87
    cyclopentyl methyl ether 81.39
    gamma-butyrolactone 263.77
    1-methoxy-2-propanol 97.89
    pyridine 63.54
    3-pentanone 43.54
    furfural 187.3
    n-dodecane 1.53
    diethylene glycol 74.33
    diisopropyl ether 10.22
    tert-amyl alcohol 39.88
    acetylacetone 115.81
    n-hexadecane 1.74
    acetophenone 52.05
    methyl propionate 55.94
    isopentyl acetate 44.64
    trichloroethylene 133.38
    n-nonanol 26.01
    cyclohexanol 69.81
    benzyl alcohol 37.23
    2-ethylhexanol 18.85
    isooctanol 31.53
    dipropyl ether 18.11
    1,2-dichlorobenzene 35.65
    ethyl lactate 49.82
    propylene carbonate 134.04
    n-methylformamide 96.16
    2-pentanol 20.47
    n-pentane 1.76
    1-propoxy-2-propanol 60.27
    1-methoxy-2-propyl acetate 71.5
    2-(2-methoxypropoxy) propanol 70.78
    mesitylene 12.12
    ε-caprolactone 181.04
    p-cymene 12.39
    epichlorohydrin 175.45
    1,1,1-trichloroethane 57.43
    2-aminoethanol 46.29
    morpholine-4-carbaldehyde 213.87
    sulfolane 602.06
    2,2,4-trimethylpentane 2.63
    2-methyltetrahydrofuran 96.34
    n-hexyl acetate 64.14
    isooctane 1.45
    2-(2-butoxyethoxy)ethanol 104.76
    sec-butyl acetate 33.14
    tert-butyl acetate 68.72
    decalin 4.8
    glycerin 79.73
    diglyme 212.51
    acrylic acid 84.81
    isopropyl myristate 19.73
    n-butyric acid 120.71
    acetyl acetate 61.82
    di(2-ethylhexyl) phthalate 29.62
    ethyl propionate 37.73
    nitromethane 225.35
    1,2-diethoxyethane 54.13
    benzonitrile 35.95
    trioctyl phosphate 26.6
    1-bromopropane 20.28
    gamma-valerolactone 307.72
    n-decanol 16.93
    triethyl phosphate 35.28
    4-methyl-2-pentanol 17.31
    propionitrile 17.41
    vinylene carbonate 110.48
    1,1,2-trichlorotrifluoroethane 237.73
    DMS 57.94
    cumene 9.77
    2-octanol 23.05
    2-hexanone 33.62
    octyl acetate 29.69
    limonene 19.8
    1,2-dimethoxyethane 99.34
    ethyl orthosilicate 32.68
    tributyl phosphate 30.04
    diacetone alcohol 108.5
    N,N-dimethylaniline 24.32
    acrylonitrile 29.02
    aniline 31.43
    1,3-propanediol 73.3
    bromobenzene 23.22
    dibromomethane 46.9
    1,1,2,2-tetrachloroethane 131.31
    2-methyl-cyclohexyl acetate 45.13
    tetrabutyl urea 40.1
    diisobutyl methanol 15.03
    2-phenylethanol 33.29
    styrene 10.46
    dioctyl adipate 43.65
    dimethyl sulfate 129.05
    ethyl butyrate 37.4
    methyl lactate 69.5
    butyl lactate 83.81
    diethyl carbonate 28.33
    propanediol butyl ether 88.24
    triethyl orthoformate 39.74
    p-tert-butyltoluene 12.72
    methyl 4-tert-butylbenzoate 83.7
    morpholine 118.0
    tert-butylamine 18.87
    n-dodecanol 11.64
    dimethoxymethane 79.88
    ethylene carbonate 102.96
    cyrene 109.71
    2-ethoxyethyl acetate 94.66
    2-ethylhexyl acetate 33.92
    1,2,4-trichlorobenzene 50.52
    4-methylpyridine 44.2
    dibutyl ether 20.01
    2,6-dimethyl-4-heptanol 15.03
    DEF 93.37
    dimethyl isosorbide 131.02
    tetrachloroethylene 106.57
    eugenol 70.39
    triacetin 106.56
    span 80 67.86
    1,4-butanediol 32.04
    1,1-dichloroethane 38.29
    2-methyl-1-pentanol 26.88
    methyl formate 74.33
    2-methyl-1-butanol 31.62
    n-decane 2.98
    butyronitrile 17.96
    3,7-dimethyl-1-octanol 23.98
    1-chlorooctane 14.34
    1-chlorotetradecane 4.98
    n-nonane 2.66
    undecane 1.98
    tert-butylcyclohexane 3.08
    cyclooctane 3.92
    cyclopentanol 79.75
    tetrahydropyran 70.18
    tert-amyl methyl ether 28.79
    2,5,8-trioxanonane 129.15
    1-hexene 4.52
    2-isopropoxyethanol 66.61
    2,2,2-trifluoroethanol 131.81
    methyl butyrate 56.89

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction