2H-Pyran, 3,6-dihydro-4-methyl-2-phenyl-

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  • Identifiers

    CAS number
    60335-71-9

    Molecular formula
    C12H14O

    SMILES
    CC1=CCOC(C1)C2=CC=CC=C2

  • Odor profile

    Fragrance
    Floral 88.29%
    Green 76.75%
    Rose 58.47%
    Herbal 55.36%
    Geranium 53.68%
    Fresh 37.83%
    Hyacinth 36.25%
    Leafy 36.2%
    Cortex 35.95%
    Metallic 34.96%

     

    Flavor
    Floral 50.73%
    Sweet 50.63%
    Woody 40.47%
    Bitter 38.29%
    Spicy 37.5%
    Herbal 36.41%
    Spice 31.87%
    Green 29.94%
    Mint 28.28%
    Warm 25.47%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.2

    pKa est.
    7.04 (neutral)

    Molecular weight
    174.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    257°C

    Flash point

    • 95.92 ˚C est.

  • Synonyms

    • 60335-71-9
    • Rosyrane
    • 4-methyl-2-phenyl-3,6-dihydro-2H-pyran
    • 3,6-Dihydro-4-methyl-2-phenyl-2H-pyran
    • 4-methyl-2-phenyl-3,6-dihydropyran
    • EINECS 262-187-7
    • 2H-Pyran, 3,6-dihydro-4-methyl-2-phenyl-
    • DTXSID00866805
    • floral pyran
    • 2H-Pyran,3,6-dihydro-4-methyl-2-phenyl-
    • SCHEMBL1471824
    • DTXCID10815046
    • 4-methyl-6-phenyl-5,6-dihydropyran
    • AKOS006276367
    • DB-306025
    • NS00054983
    • 262-187-7
    • Rosyrane Super

  • Applications

    2H-Pyran, 3,6-dihydro-4-methyl-2-phenyl- (CAS 60335-71-9) is commonly used as an intermediate and building block in fragrance and flavor chemistry, supporting fragrance creation in perfumery and aroma development for food products. It can also serve as a synthetic building block in pharmaceutical research and development. In materials science, it may be used as an intermediate for polymer-related applications and for coatings, inks, and other coating formulations. In cosmetics and personal care, it may be evaluated as a fragrance intermediate or precursor to scent components. Availability and use are subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 217.16
    methanol 110.71
    isopropanol 175.07
    water 0.4
    ethyl acetate 348.0
    n-propanol 221.14
    acetone 231.65
    n-butanol 214.74
    acetonitrile 311.74
    DMF 132.68
    toluene 324.5
    isobutanol 157.68
    1,4-dioxane 851.81
    methyl acetate 304.0
    THF 490.55
    2-butanone 300.05
    n-pentanol 160.94
    sec-butanol 179.05
    n-hexane 63.03
    ethylene glycol 48.19
    NMP 110.01
    cyclohexane 153.39
    DMSO 270.63
    n-butyl acetate 269.27
    n-octanol 114.57
    chloroform 1516.77
    n-propyl acetate 193.09
    acetic acid 180.28
    dichloromethane 1178.13
    cyclohexanone 347.19
    propylene glycol 95.45
    isopropyl acetate 164.86
    DMAc 182.9
    2-ethoxyethanol 200.22
    isopentanol 170.14
    n-heptane 75.69
    ethyl formate 179.61
    1,2-dichloroethane 635.9
    n-hexanol 244.62
    2-methoxyethanol 222.0
    isobutyl acetate 134.24
    tetrachloromethane 161.27
    n-pentyl acetate 122.42
    transcutol 1162.03
    n-heptanol 106.75
    ethylbenzene 155.0
    MIBK 142.64
    2-propoxyethanol 275.18
    tert-butanol 209.1
    MTBE 222.16
    2-butoxyethanol 172.6
    propionic acid 169.52
    o-xylene 167.95
    formic acid 35.11
    diethyl ether 382.11
    m-xylene 171.86
    p-xylene 170.37
    chlorobenzene 305.89
    dimethyl carbonate 95.65
    n-octane 27.02
    formamide 58.56
    cyclopentanone 268.35
    2-pentanone 222.83
    anisole 261.54
    cyclopentyl methyl ether 238.91
    gamma-butyrolactone 300.72
    1-methoxy-2-propanol 199.1
    pyridine 585.03
    3-pentanone 209.7
    furfural 327.16
    n-dodecane 24.76
    diethylene glycol 181.65
    diisopropyl ether 94.42
    tert-amyl alcohol 161.23
    acetylacetone 220.12
    n-hexadecane 27.87
    acetophenone 200.89
    methyl propionate 205.85
    isopentyl acetate 218.1
    trichloroethylene 977.7
    n-nonanol 108.09
    cyclohexanol 208.55
    benzyl alcohol 176.28
    2-ethylhexanol 159.87
    isooctanol 92.04
    dipropyl ether 244.25
    1,2-dichlorobenzene 242.24
    ethyl lactate 94.57
    propylene carbonate 219.14
    n-methylformamide 84.49
    2-pentanol 153.47
    n-pentane 63.1
    1-propoxy-2-propanol 224.98
    1-methoxy-2-propyl acetate 229.88
    2-(2-methoxypropoxy) propanol 222.33
    mesitylene 111.09
    ε-caprolactone 293.82
    p-cymene 104.12
    epichlorohydrin 482.03
    1,1,1-trichloroethane 508.75
    2-aminoethanol 101.57
    morpholine-4-carbaldehyde 257.4
    sulfolane 253.23
    2,2,4-trimethylpentane 28.92
    2-methyltetrahydrofuran 380.28
    n-hexyl acetate 191.06
    isooctane 26.27
    2-(2-butoxyethoxy)ethanol 312.19
    sec-butyl acetate 138.17
    tert-butyl acetate 153.49
    decalin 57.18
    glycerin 104.18
    diglyme 569.34
    acrylic acid 137.52
    isopropyl myristate 104.57
    n-butyric acid 249.46
    acetyl acetate 197.25
    di(2-ethylhexyl) phthalate 91.79
    ethyl propionate 173.9
    nitromethane 252.95
    1,2-diethoxyethane 386.19
    benzonitrile 238.43
    trioctyl phosphate 61.47
    1-bromopropane 414.77
    gamma-valerolactone 323.43
    n-decanol 86.96
    triethyl phosphate 97.09
    4-methyl-2-pentanol 93.2
    propionitrile 259.49
    vinylene carbonate 230.82
    1,1,2-trichlorotrifluoroethane 272.96
    DMS 171.64
    cumene 104.85
    2-octanol 71.35
    2-hexanone 183.93
    octyl acetate 120.75
    limonene 138.6
    1,2-dimethoxyethane 372.82
    ethyl orthosilicate 99.31
    tributyl phosphate 80.95
    diacetone alcohol 162.69
    N,N-dimethylaniline 161.04
    acrylonitrile 252.76
    aniline 256.22
    1,3-propanediol 130.28
    bromobenzene 370.73
    dibromomethane 837.51
    1,1,2,2-tetrachloroethane 780.36
    2-methyl-cyclohexyl acetate 155.51
    tetrabutyl urea 99.46
    diisobutyl methanol 102.55
    2-phenylethanol 185.91
    styrene 196.92
    dioctyl adipate 139.89
    dimethyl sulfate 110.28
    ethyl butyrate 206.35
    methyl lactate 89.74
    butyl lactate 105.03
    diethyl carbonate 152.95
    propanediol butyl ether 152.86
    triethyl orthoformate 145.63
    p-tert-butyltoluene 97.19
    methyl 4-tert-butylbenzoate 169.18
    morpholine 648.56
    tert-butylamine 158.27
    n-dodecanol 75.73
    dimethoxymethane 198.92
    ethylene carbonate 201.02
    cyrene 144.17
    2-ethoxyethyl acetate 201.81
    2-ethylhexyl acetate 181.51
    1,2,4-trichlorobenzene 268.52
    4-methylpyridine 400.0
    dibutyl ether 195.07
    2,6-dimethyl-4-heptanol 102.55
    DEF 204.43
    dimethyl isosorbide 289.85
    tetrachloroethylene 460.61
    eugenol 163.99
    triacetin 217.35
    span 80 175.93
    1,4-butanediol 68.39
    1,1-dichloroethane 570.2
    2-methyl-1-pentanol 143.21
    methyl formate 79.58
    2-methyl-1-butanol 162.99
    n-decane 37.84
    butyronitrile 269.37
    3,7-dimethyl-1-octanol 125.1
    1-chlorooctane 115.85
    1-chlorotetradecane 56.07
    n-nonane 38.28
    undecane 29.21
    tert-butylcyclohexane 48.05
    cyclooctane 55.27
    cyclopentanol 144.48
    tetrahydropyran 670.68
    tert-amyl methyl ether 157.47
    2,5,8-trioxanonane 390.9
    1-hexene 181.06
    2-isopropoxyethanol 159.05
    2,2,2-trifluoroethanol 63.72
    methyl butyrate 202.67

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction