(2alpha,3beta,12alpha,24R)-Lanost-8-ene-2,3,12,21,24,25-hexol

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  • Identifiers

    CAS number
    65694-19-1

    Molecular formula
    C30H52O6

    SMILES
    C[C@@]12CC[C@@H]([C@]1([C@H](CC3=C2CC[C@@H]4[C@@]3(C[C@H]([C@@H](C4(C)C)O)O)C)O)C)[C@@H](CC[C@H](C(C)(C)O)O)CO

    Safety labels

  • Odor profile

    Fragrance
    Woody 73.41%
    Amber 44.87%
    Sandalwood 42.71%
    Balsamic 39.75%
    Sweet 36.87%
    Dry 35.97%
    Musk 34.32%
    Cedar 33.32%
    Odorless 31.46%
    Camphoreous 30.88%

     

    Flavor
    Sweet 45.75%
    Bitter 42.72%
    Woody 36.42%
    Herbal 33.3%
    Pine 30.26%
    Odorless 29.69%
    Balsam 28.24%
    Mild 25.68%
    Camphor 23.33%
    Sweet-like 23.07%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.1

    pKa est.
    7.21 (neutral)

    Molecular weight
    508.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    291°C

    Flash point

    • 284.8 ˚C est.

  • Synonyms

    • Fasciculol C
    • 65694-19-1
    • (2R,3R,5R,10S,12S,13R,14S,17R)-4,4,10,13,14-pentamethyl-17-[(2R,5R)-1,5,6-trihydroxy-6-methylheptan-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-2,3,12-triol
    • (2R,3R,5R,10S,12S,13R,14S,17R)-4,4,10,13,14-pentamethyl-17-((2R,5R)-1,5,6-trihydroxy-6-methylheptan-2-yl)-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta(a)phenanthrene-2,3,12-triol
    • RefChem:139991
    • (2alpha,3beta,12alpha,24R)-Lanost-8-ene-2,3,12,21,24,25-hexol
    • CHEMBL2375641
    • SCHEMBL29375258
    • CHEBI:172721
    • Lanost-8-ene-2,3,12,21,24,25-hexol, (2alpha,3beta,12alpha,24R)-
    • 65694-19-1

  • Applications

    (2alpha,3beta,12alpha,24R)-Lanost-8-ene-2,3,12,21,24,25-hexol, CAS 65694-19-1, is a polyhydroxylated lanostane-type triterpenoid that can serve as a synthetic intermediate and a chiral scaffold for the preparation of steroid derivatives in pharmaceutical research; in cosmetics and personal care, its multiple hydroxyl groups may support use as a matrix-building ingredient, an emollient, and a component contributing to texture and moisturization in formulations; in industrial manufacturing, it can function as a building block for the synthesis of complex triterpenoid derivatives and related specialty chemicals; in the polymers/plastics domain, it may be used as a functionalized precursor after hydroxyl modification to access specialized polymeric materials.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 14.65
    methanol 48.79
    isopropanol 3.15
    water 0.12
    ethyl acetate 1.77
    n-propanol 5.85
    acetone 6.13
    n-butanol 2.47
    acetonitrile 1.2
    DMF 52.56
    toluene 0.58
    isobutanol 1.99
    1,4-dioxane 14.15
    methyl acetate 2.0
    THF 34.59
    2-butanone 2.86
    n-pentanol 1.62
    sec-butanol 1.11
    n-hexane 0.05
    ethylene glycol 7.19
    NMP 24.66
    cyclohexane 0.05
    DMSO 48.77
    n-butyl acetate 1.53
    n-octanol 1.66
    chloroform 3.39
    n-propyl acetate 1.16
    acetic acid 16.26
    dichloromethane 2.63
    cyclohexanone 4.3
    propylene glycol 7.24
    isopropyl acetate 1.46
    DMAc 23.11
    2-ethoxyethanol 15.52
    isopentanol 1.28
    n-heptane 0.06
    ethyl formate 2.51
    1,2-dichloroethane 1.49
    n-hexanol 2.03
    2-methoxyethanol 44.29
    isobutyl acetate 0.91
    tetrachloromethane 0.57
    n-pentyl acetate 3.15
    transcutol 26.74
    n-heptanol 2.76
    ethylbenzene 0.33
    MIBK 1.74
    2-propoxyethanol 24.54
    tert-butanol 1.63
    MTBE 0.95
    2-butoxyethanol 16.88
    propionic acid 3.73
    o-xylene 0.38
    formic acid 20.9
    diethyl ether 1.68
    m-xylene 0.5
    p-xylene 0.34
    chlorobenzene 0.71
    dimethyl carbonate 4.12
    n-octane 0.04
    formamide 19.73
    cyclopentanone 10.62
    2-pentanone 2.35
    anisole 1.67
    cyclopentyl methyl ether 3.46
    gamma-butyrolactone 12.74
    1-methoxy-2-propanol 23.32
    pyridine 6.03
    3-pentanone 1.48
    furfural 12.73
    n-dodecane 0.02
    diethylene glycol 24.66
    diisopropyl ether 0.33
    tert-amyl alcohol 0.92
    acetylacetone 5.18
    n-hexadecane 0.02
    acetophenone 2.14
    methyl propionate 2.96
    isopentyl acetate 1.54
    trichloroethylene 3.89
    n-nonanol 1.77
    cyclohexanol 0.89
    benzyl alcohol 2.76
    2-ethylhexanol 0.75
    isooctanol 1.78
    dipropyl ether 1.31
    1,2-dichlorobenzene 0.77
    ethyl lactate 2.22
    propylene carbonate 4.01
    n-methylformamide 20.64
    2-pentanol 0.75
    n-pentane 0.05
    1-propoxy-2-propanol 10.5
    1-methoxy-2-propyl acetate 5.98
    2-(2-methoxypropoxy) propanol 7.78
    mesitylene 0.27
    ε-caprolactone 4.68
    p-cymene 0.33
    epichlorohydrin 13.91
    1,1,1-trichloroethane 0.77
    2-aminoethanol 15.48
    morpholine-4-carbaldehyde 37.83
    sulfolane 21.14
    2,2,4-trimethylpentane 0.03
    2-methyltetrahydrofuran 3.86
    n-hexyl acetate 3.17
    isooctane 0.03
    2-(2-butoxyethoxy)ethanol 13.44
    sec-butyl acetate 0.65
    tert-butyl acetate 1.89
    decalin 0.04
    glycerin 19.49
    diglyme 26.54
    acrylic acid 6.04
    isopropyl myristate 0.61
    n-butyric acid 3.82
    acetyl acetate 1.95
    di(2-ethylhexyl) phthalate 1.82
    ethyl propionate 1.09
    nitromethane 18.42
    1,2-diethoxyethane 3.7
    benzonitrile 1.25
    trioctyl phosphate 1.2
    1-bromopropane 0.5
    gamma-valerolactone 31.91
    n-decanol 0.81
    triethyl phosphate 0.9
    4-methyl-2-pentanol 0.62
    propionitrile 1.03
    vinylene carbonate 4.87
    1,1,2-trichlorotrifluoroethane 18.38
    DMS 3.02
    cumene 0.25
    2-octanol 1.04
    2-hexanone 1.41
    octyl acetate 1.18
    limonene 0.39
    1,2-dimethoxyethane 15.11
    ethyl orthosilicate 0.92
    tributyl phosphate 0.87
    diacetone alcohol 4.56
    N,N-dimethylaniline 1.44
    acrylonitrile 2.21
    aniline 1.65
    1,3-propanediol 14.43
    bromobenzene 0.51
    dibromomethane 1.28
    1,1,2,2-tetrachloroethane 2.84
    2-methyl-cyclohexyl acetate 1.41
    tetrabutyl urea 1.42
    diisobutyl methanol 0.44
    2-phenylethanol 3.45
    styrene 0.35
    dioctyl adipate 1.46
    dimethyl sulfate 9.02
    ethyl butyrate 1.07
    methyl lactate 6.67
    butyl lactate 5.06
    diethyl carbonate 0.7
    propanediol butyl ether 13.99
    triethyl orthoformate 1.42
    p-tert-butyltoluene 0.36
    methyl 4-tert-butylbenzoate 5.48
    morpholine 18.67
    tert-butylamine 0.47
    n-dodecanol 0.37
    dimethoxymethane 33.56
    ethylene carbonate 3.3
    cyrene 10.06
    2-ethoxyethyl acetate 8.02
    2-ethylhexyl acetate 1.02
    1,2,4-trichlorobenzene 1.19
    4-methylpyridine 2.9
    dibutyl ether 0.65
    2,6-dimethyl-4-heptanol 0.44
    DEF 4.0
    dimethyl isosorbide 12.54
    tetrachloroethylene 2.88
    eugenol 7.47
    triacetin 5.29
    span 80 7.35
    1,4-butanediol 3.96
    1,1-dichloroethane 0.76
    2-methyl-1-pentanol 0.91
    methyl formate 12.63
    2-methyl-1-butanol 1.15
    n-decane 0.05
    butyronitrile 0.88
    3,7-dimethyl-1-octanol 0.91
    1-chlorooctane 0.32
    1-chlorotetradecane 0.06
    n-nonane 0.05
    undecane 0.03
    tert-butylcyclohexane 0.04
    cyclooctane 0.03
    cyclopentanol 2.1
    tetrahydropyran 3.08
    tert-amyl methyl ether 0.74
    2,5,8-trioxanonane 13.41
    1-hexene 0.19
    2-isopropoxyethanol 6.37
    2,2,2-trifluoroethanol 5.88
    methyl butyrate 1.37

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction