2,6-Dihydroxyethylaminotoluene

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  • Identifiers

    CAS number
    149330-25-6

    Molecular formula
    C11H18N2O2

    SMILES
    CC1=C(C=CC=C1NCCO)NCCO

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 42.32%
    Fishy 42.25%
    Sweet 28.51%
    Animal 26.74%
    Savory 26.48%
    Cheesy 26.16%
    Ripe 24.22%
    Meaty 23.86%
    Cooling 19.83%
    Bitter 17.63%

     

    Flavor
    Odorless 47.56%
    Bitter 36.89%
    Mild 36.81%
    Sweet 29.66%
    Sweet-like 24.78%
    Sulfurous 24.52%
    Meaty 22.56%
    Fruity 22.12%
    Very slight 20.83%
    Orange flower 20.51%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.9

    pKa est.
    5.71 (weak acid)

    Molecular weight
    210.27 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    478°C

    Flash point

    • 219.95 ˚C est.

  • Synonyms

    • 149330-25-6
    • 2,6-Bis[(2-hydroxyethyl)amino]toluene
    • 2,6-DIHYDROXYETHYLAMINOTOLUENE
    • Colorex VAS
    • HC Purple BS
    • H.C. Violett AS
    • Ethanol, 2,2'-[(2-methyl-1,3-phenylene)diimino]bis-
    • 2,6-bis((2-hydroxyethyl)amino)toluene
    • UNII-I50F7J73SU
    • I50F7J73SU
    • 2,6-Dihydroxyethylaminotoluene [INCI]
    • Ethanol, 2,2'-((2-methyl-1,3-phenylene)diimino)bis-
    • DTXSID30164225
    • RefChem:83253
    • DTXCID5086716
    • 2,6-bis(2-hydroxyethylamino)toulene
    • 604-688-9
    • 2,2'-((2-Methyl-1,3-phenylene)bis(azanediyl))diethanol
    • Bis-2,6-N,N-(2-hydroxyethyl)diaminotoluene
    • MFCD08703311
    • 2-[3-(2-hydroxyethylamino)-2-methylanilino]ethanol
    • 2-({3-[(2-hydroxyethyl)amino]-2-methylphenyl}amino)ethan-1-ol
    • 2,2'-[(2-Methyl-1,3-phenylene)diimino]bis[ethanol]; 2,6-Bis(2'-hydroxyethylamino)-1-methylbenzene; 2,6-Bis[(2-hydroxyethyl)amino]toluene; 2-([3-[(2-Hydroxyethyl)amino]-2-methylphenyl]amino)ethanol; HC Purple BS
    • SCHEMBL34077
    • 2-[3-(2-hydroxyethylamino)-2-methyl-anilino]ethanol
    • N,N-Di(2-hydroxyethyl)-2-methyl-1,3-phenylenediamine
    • MSK002079
    • AKOS015842318
    • 2,6-bis(beta-hydroxyethylamino)toluene
    • AC-8298
    • DS-1938
    • SY038097
    • B5854
    • CS-0153513
    • NS00021678
    • 330B256
    • Q27280452
    • 2,2'-(2-Methyl-1,3-phenylene)bis(azanediyl)diethanol
    • 2,2'-((2-Methyl-1,3-phenylene)-bis(azanediyl))diethanol
    • 2,2'-[(2-Methyl-1,3-phenylene)bis(azanediyl)]di(ethan-1-ol)
    • 2 pound not2'-((2-Methyl-1 pound not3-phenylene)bis(azanediyl))diethanol
    • 149330-25-6

  • Applications

    2,6-Dihydroxyethylaminotoluene is primarily used as an intermediate in organic synthesis. In industry, it is commonly employed as a building block for the production of dyes and pigments, and as a precursor in polymer and resin formulations (including polyurethanes and epoxies). It is also evaluated in fragrance chemistry as a potential odorant or fragrance intermediate, and may find use in cosmetics and personal care formulations as a colorant-related intermediate. Additionally, it can serve as a dye/pigment precursor in coatings and inks, depending on regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 36.58
    methanol 148.27
    isopropanol 10.29
    water 22.12
    ethyl acetate 9.4
    n-propanol 25.01
    acetone 13.21
    n-butanol 17.09
    acetonitrile 5.3
    DMF 183.32
    toluene 1.15
    isobutanol 14.67
    1,4-dioxane 18.71
    methyl acetate 6.98
    THF 49.1
    2-butanone 7.64
    n-pentanol 13.53
    sec-butanol 9.52
    n-hexane 0.27
    ethylene glycol 88.94
    NMP 179.49
    cyclohexane 0.5
    DMSO 718.9
    n-butyl acetate 9.5
    n-octanol 7.1
    chloroform 11.6
    n-propyl acetate 8.76
    acetic acid 174.81
    dichloromethane 16.23
    cyclohexanone 38.75
    propylene glycol 60.01
    isopropyl acetate 5.65
    DMAc 147.27
    2-ethoxyethanol 67.73
    isopentanol 13.87
    n-heptane 0.6
    ethyl formate 22.25
    1,2-dichloroethane 12.86
    n-hexanol 15.47
    2-methoxyethanol 141.25
    isobutyl acetate 5.98
    tetrachloromethane 3.55
    n-pentyl acetate 6.66
    transcutol 78.22
    n-heptanol 10.31
    ethylbenzene 1.31
    MIBK 6.67
    2-propoxyethanol 50.7
    tert-butanol 18.62
    MTBE 4.6
    2-butoxyethanol 28.5
    propionic acid 50.61
    o-xylene 2.44
    formic acid 260.52
    diethyl ether 2.71
    m-xylene 2.28
    p-xylene 1.85
    chlorobenzene 4.52
    dimethyl carbonate 13.36
    n-octane 0.37
    formamide 234.23
    cyclopentanone 69.61
    2-pentanone 8.15
    anisole 5.07
    cyclopentyl methyl ether 15.04
    gamma-butyrolactone 113.11
    1-methoxy-2-propanol 54.05
    pyridine 13.13
    3-pentanone 6.45
    furfural 98.14
    n-dodecane 0.31
    diethylene glycol 82.42
    diisopropyl ether 1.44
    tert-amyl alcohol 15.51
    acetylacetone 20.85
    n-hexadecane 0.34
    acetophenone 12.43
    methyl propionate 14.55
    isopentyl acetate 9.95
    trichloroethylene 26.63
    n-nonanol 7.0
    cyclohexanol 15.0
    benzyl alcohol 14.16
    2-ethylhexanol 8.04
    isooctanol 8.73
    dipropyl ether 4.89
    1,2-dichlorobenzene 7.21
    ethyl lactate 19.21
    propylene carbonate 49.29
    n-methylformamide 119.68
    2-pentanol 5.66
    n-pentane 0.24
    1-propoxy-2-propanol 28.18
    1-methoxy-2-propyl acetate 18.26
    2-(2-methoxypropoxy) propanol 24.76
    mesitylene 2.11
    ε-caprolactone 38.56
    p-cymene 3.1
    epichlorohydrin 63.58
    1,1,1-trichloroethane 6.5
    2-aminoethanol 87.63
    morpholine-4-carbaldehyde 107.76
    sulfolane 247.33
    2,2,4-trimethylpentane 0.44
    2-methyltetrahydrofuran 19.45
    n-hexyl acetate 9.17
    isooctane 0.3
    2-(2-butoxyethoxy)ethanol 32.83
    sec-butyl acetate 4.57
    tert-butyl acetate 8.56
    decalin 0.6
    glycerin 135.08
    diglyme 58.1
    acrylic acid 66.74
    isopropyl myristate 3.58
    n-butyric acid 54.86
    acetyl acetate 11.21
    di(2-ethylhexyl) phthalate 9.89
    ethyl propionate 7.52
    nitromethane 160.95
    1,2-diethoxyethane 9.64
    benzonitrile 10.06
    trioctyl phosphate 7.69
    1-bromopropane 3.05
    gamma-valerolactone 101.78
    n-decanol 5.1
    triethyl phosphate 9.86
    4-methyl-2-pentanol 4.86
    propionitrile 5.88
    vinylene carbonate 40.77
    1,1,2-trichlorotrifluoroethane 125.25
    DMS 11.86
    cumene 1.91
    2-octanol 5.04
    2-hexanone 7.02
    octyl acetate 5.75
    limonene 4.4
    1,2-dimethoxyethane 48.96
    ethyl orthosilicate 8.82
    tributyl phosphate 8.32
    diacetone alcohol 25.21
    N,N-dimethylaniline 6.82
    acrylonitrile 13.75
    aniline 8.14
    1,3-propanediol 84.28
    bromobenzene 3.26
    dibromomethane 7.65
    1,1,2,2-tetrachloroethane 24.71
    2-methyl-cyclohexyl acetate 11.57
    tetrabutyl urea 11.75
    diisobutyl methanol 4.64
    2-phenylethanol 14.85
    styrene 1.29
    dioctyl adipate 8.67
    dimethyl sulfate 48.21
    ethyl butyrate 8.79
    methyl lactate 35.84
    butyl lactate 16.01
    diethyl carbonate 7.92
    propanediol butyl ether 30.24
    triethyl orthoformate 8.92
    p-tert-butyltoluene 3.21
    methyl 4-tert-butylbenzoate 18.88
    morpholine 35.14
    tert-butylamine 5.82
    n-dodecanol 3.7
    dimethoxymethane 36.52
    ethylene carbonate 31.02
    cyrene 46.43
    2-ethoxyethyl acetate 12.56
    2-ethylhexyl acetate 7.34
    1,2,4-trichlorobenzene 10.56
    4-methylpyridine 9.69
    dibutyl ether 3.14
    2,6-dimethyl-4-heptanol 4.64
    DEF 31.04
    dimethyl isosorbide 43.35
    tetrachloroethylene 21.05
    eugenol 23.5
    triacetin 16.48
    span 80 23.48
    1,4-butanediol 41.25
    1,1-dichloroethane 4.61
    2-methyl-1-pentanol 11.68
    methyl formate 70.9
    2-methyl-1-butanol 14.72
    n-decane 0.49
    butyronitrile 6.47
    3,7-dimethyl-1-octanol 6.42
    1-chlorooctane 2.05
    1-chlorotetradecane 0.94
    n-nonane 0.43
    undecane 0.38
    tert-butylcyclohexane 0.55
    cyclooctane 0.33
    cyclopentanol 26.31
    tetrahydropyran 9.2
    tert-amyl methyl ether 5.39
    2,5,8-trioxanonane 43.29
    1-hexene 0.85
    2-isopropoxyethanol 29.95
    2,2,2-trifluoroethanol 79.45
    methyl butyrate 13.38

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction