2,5-Dimethyl-3-(2-methylpropyl)pyrazine

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    32736-94-0

    Molecular formula
    C10H16N2

    SMILES
    CC1=CN=C(C(=N1)CC(C)C)C

  • Odor profile

    Earthy 49.92%
    Nutty 48.72%
    Green 48.53%
    Burnt 41.79%
    Roasted 41.67%
    Fruity 41.02%
    Cocoa 37.49%
    Woody 36.48%
    Musty 35.3%
    Hazelnut 33.83%

    Scent© AI

  • Properties

    XLogP3-AA
    2.2

    pKa est.
    5.43 (weak acid)

    Molecular weight
    164.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point est.
    235°C

    Flash point est.
    84.17 ˚C

  • Synonyms

    • 2,5-dimethyl-3-(2-methylpropyl)pyrazine
    • 32736-94-0
    • 2,5-Dimethyl-3-isobutylpyrazine
    • Pyrazine, 2,5-dimethyl-3-(2-methylpropyl)-
    • 2-Isobutyl-3,6-dimethyl-pyrazine
    • Pyrazine, 3-isobutyl-2,5-dimethyl-
    • 2,5-Dimethyl-6-isobutylpyrazine
    • FEMA No. 4100, 3,6-dimethyl-
    • UNII-17J126RD59
    • 3-(2-Methylpropyl)-2,5-dimethylpyrazine
    • 3-Isobutyl-2,5-dimethylpyrazine
    • 17J126RD59
    • 3,6-Dimethyl-2-isobutylpyrazine
    • DTXSID30186407
    • SCHEMBL3458549
    • DTXCID00108898
    • CHEBI:207389
    • DB-116488
    • NS00113883
    • Q27251914

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 115.47
    methanol 104.37
    isopropanol 117.98
    water 0.49
    ethyl acetate 116.08
    n-propanol 132.8
    acetone 155.09
    n-butanol 131.54
    acetonitrile 89.3
    DMF 236.64
    toluene 170.31
    isobutanol 140.54
    1,4-dioxane 241.7
    methyl acetate 122.14
    THF 474.87
    2-butanone 162.71
    n-pentanol 114.63
    sec-butanol 140.43
    n-hexane 65.17
    ethylene glycol 32.15
    NMP 324.75
    cyclohexane 110.4
    DMSO 178.18
    n-butyl acetate 235.0
    n-octanol 136.23
    chloroform 721.58
    n-propyl acetate 98.57
    acetic acid 118.54
    dichloromethane 539.96
    cyclohexanone 351.23
    propylene glycol 69.99
    isopropyl acetate 91.78
    DMAc 236.4
    2-ethoxyethanol 91.25
    isopentanol 132.16
    n-heptane 79.41
    ethyl formate 112.32
    1,2-dichloroethane 252.59
    n-hexanol 265.12
    2-methoxyethanol 137.85
    isobutyl acetate 93.66
    tetrachloromethane 143.45
    n-pentyl acetate 130.52
    transcutol 225.15
    n-heptanol 127.94
    ethylbenzene 114.49
    MIBK 105.89
    2-propoxyethanol 205.65
    tert-butanol 145.95
    MTBE 152.47
    2-butoxyethanol 133.6
    propionic acid 121.27
    o-xylene 138.99
    formic acid 28.47
    diethyl ether 112.69
    m-xylene 135.08
    p-xylene 162.93
    chlorobenzene 228.24
    dimethyl carbonate 59.18
    n-octane 33.24
    formamide 30.79
    cyclopentanone 378.63
    2-pentanone 130.64
    anisole 131.65
    cyclopentyl methyl ether 234.35
    gamma-butyrolactone 361.0
    1-methoxy-2-propanol 129.46
    pyridine 263.25
    3-pentanone 123.45
    furfural 340.66
    n-dodecane 30.62
    diethylene glycol 118.39
    diisopropyl ether 58.65
    tert-amyl alcohol 157.13
    acetylacetone 137.86
    n-hexadecane 34.06
    acetophenone 142.06
    methyl propionate 116.21
    isopentyl acetate 211.11
    trichloroethylene 514.06
    n-nonanol 113.31
    cyclohexanol 200.95
    benzyl alcohol 125.71
    2-ethylhexanol 188.9
    isooctanol 103.88
    dipropyl ether 153.53
    1,2-dichlorobenzene 225.36
    ethyl lactate 72.14
    propylene carbonate 264.42
    n-methylformamide 84.65
    2-pentanol 107.76
    n-pentane 51.34
    1-propoxy-2-propanol 186.82
    1-methoxy-2-propyl acetate 166.99
    2-(2-methoxypropoxy) propanol 138.49
    mesitylene 96.42
    ε-caprolactone 268.64
    p-cymene 133.51
    epichlorohydrin 322.51
    1,1,1-trichloroethane 313.1
    2-aminoethanol 65.17
    morpholine-4-carbaldehyde 245.89
    sulfolane 411.89
    2,2,4-trimethylpentane 40.99
    2-methyltetrahydrofuran 341.2
    n-hexyl acetate 189.2
    isooctane 25.86
    2-(2-butoxyethoxy)ethanol 149.45
    sec-butyl acetate 78.59
    tert-butyl acetate 108.51
    decalin 58.54
    glycerin 74.65
    diglyme 219.92
    acrylic acid 107.17
    isopropyl myristate 92.11
    n-butyric acid 171.28
    acetyl acetate 92.57
    di(2-ethylhexyl) phthalate 109.84
    ethyl propionate 88.22
    nitromethane 124.79
    1,2-diethoxyethane 126.64
    benzonitrile 199.9
    trioctyl phosphate 84.18
    1-bromopropane 218.25
    gamma-valerolactone 358.81
    n-decanol 89.09
    triethyl phosphate 87.04
    4-methyl-2-pentanol 78.5
    propionitrile 119.47
    vinylene carbonate 244.75
    1,1,2-trichlorotrifluoroethane 234.3
    DMS 133.83
    cumene 99.4
    2-octanol 103.9
    2-hexanone 129.99
    octyl acetate 124.24
    limonene 180.07
    1,2-dimethoxyethane 168.99
    ethyl orthosilicate 83.64
    tributyl phosphate 90.3
    diacetone alcohol 118.49
    N,N-dimethylaniline 120.03
    acrylonitrile 129.05
    aniline 149.73
    1,3-propanediol 92.28
    bromobenzene 264.3
    dibromomethane 420.56
    1,1,2,2-tetrachloroethane 469.29
    2-methyl-cyclohexyl acetate 160.29
    tetrabutyl urea 116.93
    diisobutyl methanol 95.39
    2-phenylethanol 188.64
    styrene 123.75
    dioctyl adipate 133.28
    dimethyl sulfate 97.42
    ethyl butyrate 138.93
    methyl lactate 76.82
    butyl lactate 118.8
    diethyl carbonate 101.06
    propanediol butyl ether 147.34
    triethyl orthoformate 106.62
    p-tert-butyltoluene 120.21
    methyl 4-tert-butylbenzoate 157.98
    morpholine 242.93
    tert-butylamine 114.12
    n-dodecanol 75.81
    dimethoxymethane 130.41
    ethylene carbonate 188.85
    cyrene 150.91
    2-ethoxyethyl acetate 132.56
    2-ethylhexyl acetate 186.22
    1,2,4-trichlorobenzene 264.5
    4-methylpyridine 283.88
    dibutyl ether 129.55
    2,6-dimethyl-4-heptanol 95.39
    DEF 150.85
    dimethyl isosorbide 250.84
    tetrachloroethylene 304.14
    eugenol 139.22
    triacetin 143.78
    span 80 162.25
    1,4-butanediol 56.59
    1,1-dichloroethane 286.99
    2-methyl-1-pentanol 126.04
    methyl formate 91.75
    2-methyl-1-butanol 142.74
    n-decane 43.87
    butyronitrile 146.59
    3,7-dimethyl-1-octanol 129.09
    1-chlorooctane 123.87
    1-chlorotetradecane 61.11
    n-nonane 45.01
    undecane 35.6
    tert-butylcyclohexane 56.68
    cyclooctane 43.24
    cyclopentanol 218.5
    tetrahydropyran 291.59
    tert-amyl methyl ether 142.41
    2,5,8-trioxanonane 179.22
    1-hexene 138.91
    2-isopropoxyethanol 84.12
    2,2,2-trifluoroethanol 47.79
    methyl butyrate 132.31

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Chicory root, roasted 1a 68650-43-1 Cichorium intybus L., fam. Asteraceae (Compositae) 0.06%
Chicory root, roasted 1b 68650-43-1 Cichorium intybus L., fam. Asteraceae (Compositae) 0.09%