2,5-Diaminotoluene sulfate

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  • Identifiers

    CAS number
    615-50-9

    Molecular formula
    C7H12N2O4S

    SMILES
    CC1=C(C=CC(=C1)N)N.OS(=O)(=O)O

    Safety labels

    Acute Toxic
    Acute Toxic

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Animal 39.25%
    Phenolic 34.56%
    Meaty 34.52%
    Burnt 33.31%
    Sweet 32.32%
    Cheesy 30.73%
    Fishy 30.71%
    Smoky 28.96%
    Musty 28.56%
    Ripe 27.57%

     

    Flavor
    Meaty 36.75%
    Phenolic 34.39%
    Mild 29.57%
    Sulfurous 28.75%
    Roasted 27.13%
    Medicinal 26.9%
    Coffee 24.11%
    Fishy 22.14%
    Penetrating 21.98%
    Egg 21.8%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    3.49 (weak acid)

    Molecular weight
    220.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    284°C

    Melting point expt.

    • 40.6 °C

    Flash point

    • 138.21 ˚C est.

    Solubility expt.

    • less than 1 mg/mL at 68 °F (NTP, 1992)
    • In water, 5.03 g/L at 20 °C
    • Soluble in water and ethanol
    • In acetone/water 1:1 <1 g/L; in dimethylsulfoxide: 5 to 15 g/L; in ethanol: 1 to 10 g/L
    • Solubility in water: good

  • Synonyms

    • 2,5-Diaminotoluene sulfate
    • 615-50-9
    • Fouramine STD
    • Toluene-2,5-diamine sulfate
    • C.I. Oxidation Base 4
    • p-Toluylenediamine sulfate
    • 2-Methyl-1,4-benzenediamine sulfate
    • CI Oxidation Base 4
    • Toluene-2,5-diamine, sulfate
    • Rodol BLFX
    • para-Toluenediamine sulphate
    • NCI-C01832
    • CI 76043
    • para-Toluylenediamine sulphate
    • C.I. 76043
    • Toluylene-2,5-diamine sulphate
    • p-Toluenediamine sulphate
    • 2,5-TDS
    • p-Tolylenediamine sulphate
    • p-Toluylenediamine sulphate
    • 2,5-Diaminotoluene sulphate
    • 8PSD05SPE2
    • 2-Methyl-para-phenylenediamine sulphate
    • Toluene-2,5-diamine, sulfate (1:1)
    • JAROCOL TDS
    • COLOREX 25DTS
    • NSC-1703
    • 1,4-Benzenediamine, 2-methyl-, sulfate (1:1)
    • CHEBI:156544
    • RefChem:82756
    • DTXCID90405
    • PARA-TOLYLENEDIAMINE SULPHATE
    • 210-431-8
    • 228-871-4
    • DTXSID50872532
    • 2-methylbenzene-1,4-diamine sulfate
    • 6369-59-1
    • 2,5-Toluenediamine sulfate
    • 1,4-Benzenediamine, 2-methyl-, sulfate
    • 2-Methyl-p-phenylenediamine sulfate
    • P-TOLUENEDIAMINE SULFATE
    • 2-Methyl-p-phenylenediamine sulphate
    • Toluene-2,5-diamine sulphate
    • Toluylene-2,5-diamine sulfate
    • p-Tolylenediamine sulfate
    • MFCD00013003
    • C7H12N2O4S
    • 2-methylbenzene-1,4-diamine;sulfuric acid
    • CCRIS 595
    • HSDB 2179
    • p-Diaminotoluene sulfate
    • EINECS 228-871-4
    • UNII-8PSD05SPE2
    • CCRIS 7629
    • 2-methylbenzene-1,4-diamine; sulfuric acid
    • NSC 1703
    • EINECS 210-431-8
    • Toluene-2, sulfate
    • C.I. 76043 (VAN)
    • 2-Methyl-1,4-benzenediamine sulfate (1:1)
    • EC 210-431-8
    • SCHEMBL94577
    • Toluene-2, sulfate (1:1)
    • Tolylene-2,5-diamine Sulfate
    • PARATOLUENEDIAMINE SULFATE
    • SCHEMBL29151724
    • NSC1703
    • KZTWOUOZKZQDMN-UHFFFAOYSA-N
    • WLN: ZR DZ B1 &S-O4
    • 2,5-Diaminotoluene sulfate, 97%
    • 1, 2-methyl-, sulfate (1:1)
    • MSK000653
    • SBB058779
    • AKOS015897352
    • GS-3194
    • 2-Methyl-p-phenylenediamine hemisulphate
    • 2-Methyl-p-phenylenediamine sulfate salt
    • AC-12224
    • 2,5-DIAMINOTOLUENE SULFATE [HSDB]
    • DB-053928
    • 2-methylbenzene-1,4-diamine sulfate (1:1)
    • D1602
    • NS00078380
    • F87368
    • 1,4-Benzenediamine, 2-methyl-, sulfate (1:?)
    • Q27270862
    • 2,5-Diaminotoluene sulfate 100 microg/mL in Methanol:Water
    • 2-Methyl-p-phenylenediamine sulfate salt, analytical standard
    • 2,5-Diaminotoluene sulfate (2-Methyl-p-phenylenediamine sulfate)
    • 615-50-9

  • Applications

    2,5-Diaminotoluene sulfate is primarily used as an intermediate in the synthesis of azo dyes and pigment compounds, with its two amine groups undergoing diazotization and coupling to form colorants for textiles, coatings, and printing inks. The sulfate salt enhances water solubility and facilitates formulation in dye and pigment products. In the cosmetics/personal care sector, it may serve as a starting material for hair dye intermediates and related color chemistries. It can also be evaluated for use as a chemical intermediate in polymer and plastics applications, depending on formulation needs and regulatory controls. Real-world use depends on local regulations and handling requirements.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 58.15
    methanol 123.49
    isopropanol 29.06
    water 23.07
    ethyl acetate 67.19
    n-propanol 38.2
    acetone 100.51
    n-butanol 33.33
    acetonitrile 88.07
    DMF 122.87
    toluene 5.57
    isobutanol 18.55
    1,4-dioxane 99.91
    methyl acetate 71.56
    THF 257.81
    2-butanone 67.39
    n-pentanol 21.85
    sec-butanol 17.51
    n-hexane 0.83
    ethylene glycol 22.9
    NMP 102.66
    cyclohexane 0.58
    DMSO 172.75
    n-butyl acetate 49.32
    n-octanol 14.67
    chloroform 50.68
    n-propyl acetate 25.03
    acetic acid 137.63
    dichloromethane 29.06
    cyclohexanone 62.95
    propylene glycol 17.17
    isopropyl acetate 29.6
    DMAc 139.33
    2-ethoxyethanol 58.04
    isopentanol 22.96
    n-heptane 2.47
    ethyl formate 81.89
    1,2-dichloroethane 20.75
    n-hexanol 46.53
    2-methoxyethanol 119.58
    isobutyl acetate 14.63
    tetrachloromethane 20.73
    n-pentyl acetate 23.18
    transcutol 53.94
    n-heptanol 28.15
    ethylbenzene 2.99
    MIBK 26.59
    2-propoxyethanol 108.88
    tert-butanol 41.92
    MTBE 29.5
    2-butoxyethanol 59.25
    propionic acid 57.47
    o-xylene 5.47
    formic acid 165.25
    diethyl ether 25.89
    m-xylene 6.54
    p-xylene 4.45
    chlorobenzene 16.16
    dimethyl carbonate 48.68
    n-octane 1.08
    formamide 181.25
    cyclopentanone 156.72
    2-pentanone 52.55
    anisole 18.09
    cyclopentyl methyl ether 46.27
    gamma-butyrolactone 195.2
    1-methoxy-2-propanol 66.79
    pyridine 42.18
    3-pentanone 34.05
    furfural 158.87
    n-dodecane 0.83
    diethylene glycol 81.12
    diisopropyl ether 6.11
    tert-amyl alcohol 28.16
    acetylacetone 76.19
    n-hexadecane 0.91
    acetophenone 19.77
    methyl propionate 56.95
    isopentyl acetate 33.49
    trichloroethylene 56.04
    n-nonanol 13.79
    cyclohexanol 13.27
    benzyl alcohol 15.73
    2-ethylhexanol 22.11
    isooctanol 19.77
    dipropyl ether 24.58
    1,2-dichlorobenzene 17.86
    ethyl lactate 18.64
    propylene carbonate 80.08
    n-methylformamide 136.28
    2-pentanol 14.44
    n-pentane 0.79
    1-propoxy-2-propanol 57.9
    1-methoxy-2-propyl acetate 48.57
    2-(2-methoxypropoxy) propanol 27.52
    mesitylene 4.88
    ε-caprolactone 52.28
    p-cymene 6.92
    epichlorohydrin 129.76
    1,1,1-trichloroethane 39.03
    2-aminoethanol 38.56
    morpholine-4-carbaldehyde 97.27
    sulfolane 145.06
    2,2,4-trimethylpentane 1.1
    2-methyltetrahydrofuran 81.3
    n-hexyl acetate 22.59
    isooctane 0.97
    2-(2-butoxyethoxy)ethanol 38.58
    sec-butyl acetate 13.43
    tert-butyl acetate 36.98
    decalin 0.83
    glycerin 50.08
    diglyme 79.52
    acrylic acid 52.16
    isopropyl myristate 8.32
    n-butyric acid 89.79
    acetyl acetate 45.13
    di(2-ethylhexyl) phthalate 12.46
    ethyl propionate 23.92
    nitromethane 329.54
    1,2-diethoxyethane 27.98
    benzonitrile 22.84
    trioctyl phosphate 10.96
    1-bromopropane 8.21
    gamma-valerolactone 179.49
    n-decanol 10.12
    triethyl phosphate 16.07
    4-methyl-2-pentanol 11.21
    propionitrile 41.25
    vinylene carbonate 72.37
    1,1,2-trichlorotrifluoroethane 91.63
    DMS 18.88
    cumene 3.66
    2-octanol 12.7
    2-hexanone 28.26
    octyl acetate 13.75
    limonene 9.16
    1,2-dimethoxyethane 89.38
    ethyl orthosilicate 16.25
    tributyl phosphate 11.16
    diacetone alcohol 51.11
    N,N-dimethylaniline 13.69
    acrylonitrile 58.26
    aniline 18.93
    1,3-propanediol 63.03
    bromobenzene 12.34
    dibromomethane 16.81
    1,1,2,2-tetrachloroethane 43.65
    2-methyl-cyclohexyl acetate 20.0
    tetrabutyl urea 15.2
    diisobutyl methanol 11.39
    2-phenylethanol 31.77
    styrene 3.37
    dioctyl adipate 10.79
    dimethyl sulfate 77.64
    ethyl butyrate 30.5
    methyl lactate 40.18
    butyl lactate 19.37
    diethyl carbonate 18.95
    propanediol butyl ether 24.55
    triethyl orthoformate 21.76
    p-tert-butyltoluene 7.63
    methyl 4-tert-butylbenzoate 30.9
    morpholine 78.89
    tert-butylamine 16.52
    n-dodecanol 7.45
    dimethoxymethane 97.73
    ethylene carbonate 61.2
    cyrene 34.91
    2-ethoxyethyl acetate 32.8
    2-ethylhexyl acetate 24.47
    1,2,4-trichlorobenzene 21.6
    4-methylpyridine 38.16
    dibutyl ether 10.19
    2,6-dimethyl-4-heptanol 11.39
    DEF 49.5
    dimethyl isosorbide 59.65
    tetrachloroethylene 40.18
    eugenol 30.82
    triacetin 18.94
    span 80 23.38
    1,4-butanediol 18.67
    1,1-dichloroethane 25.1
    2-methyl-1-pentanol 16.28
    methyl formate 120.31
    2-methyl-1-butanol 18.92
    n-decane 1.38
    butyronitrile 39.65
    3,7-dimethyl-1-octanol 11.68
    1-chlorooctane 6.63
    1-chlorotetradecane 2.54
    n-nonane 1.19
    undecane 1.04
    tert-butylcyclohexane 1.26
    cyclooctane 0.43
    cyclopentanol 26.84
    tetrahydropyran 41.28
    tert-amyl methyl ether 20.54
    2,5,8-trioxanonane 55.39
    1-hexene 3.34
    2-isopropoxyethanol 31.08
    2,2,2-trifluoroethanol 89.35
    methyl butyrate 32.57

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction