2,4,5-Trichlorophenoxyacetic acid

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  • Identifiers

    CAS number
    93-76-5

    Molecular formula
    C8H5Cl3O3

    SMILES
    C1=C(C(=CC(=C1Cl)Cl)Cl)OCC(=O)O

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 53.37%
    Musk 24.45%
    Phenolic 23.67%
    Sweet 22.92%
    Powdery 22.29%
    Fatty 22.12%
    Dry 21.86%
    Milky 21.73%
    Savory 21.36%
    Burnt 21.1%

     

    Flavor
    Odorless 58.14%
    Bitter 42.1%
    Mild 41.87%
    Bland 27.35%
    Very mild 25.76%
    Sweet-like 22.24%
    Orange flower 20.47%
    Yeast 20.21%
    Sour 19.55%
    Bread crust 19.53%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.3

    pKa est.
    7.06 (neutral)

    Molecular weight
    255.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 316 °F (NTP, 1992)
    • 153 °C
    • 316 °F
    • 307 °F

    Boiling point

    • Decomposes (NTP, 1992)
    • Decomposes
    • decomposes

    Flash point

    • 180.74 ˚C est.

    Solubility expt.

    • less than 0.1 mg/mL at 69.8 °F (NTP, 1992)
    • 0.028% AT 25 °C
    • VERY SLIGHTLY SOL IN PETROLEUM ETHER
    • 590 MG/KG IN ETHANOL OR ISOPROPYL ALC
    • 1.05 x 10(-3) M at 25 °C
    • For more Solubility (Complete) data for 2,4,5-T (6 total), please visit the HSDB record page.
    • (77 °F): 0.03%

  • Synonyms

    • 2,4,5-trichlorophenoxyacetic acid
    • 93-76-5
    • 2,4,5-T
    • 2-(2,4,5-trichlorophenoxy)acetic acid
    • Fortex
    • Trioxone
    • (2,4,5-Trichlorophenoxy)acetic acid
    • Trioxon
    • Fence rider
    • BCF-Bushkiller
    • Tippontormona
    • Arbokan
    • Phortox
    • Verton 2T
    • Forron
    • Reddon
    • Reddox
    • Line rider
    • Brush Killer
    • Fruitone A
    • Envert-T
    • Decamine 4T
    • Forst U 46
    • Brush RHAP
    • Acetic acid, (2,4,5-trichlorophenoxy)-
    • Brushtox
    • Crossbow
    • Spontox
    • Tippon
    • Inverton 245
    • Esteron 245
    • VEON
    • Ded-weed brush killer
    • Farmco fence rider
    • Veon 245
    • Estercide t-2 and t-245
    • Debroussaillant concentre
    • Rcra waste number U232
    • Visko rhap low volatile ester
    • Debroussaillant super concentre
    • Brush-off 445 low volatile brush killer
    • Ded-weed lv-6 brush kil and t-5 brush kil
    • Verton 2-T
    • 2,4,5-Trichlorphenoxyessigsaeure
    • 2,4,5-T acid
    • Kwas 2,4,5-trojchlorofenoksyoctowy
    • (2,4,5-Trichlorphenoxy)essigsaeure
    • (2,4,5-Trichloor-fenoxy)-azijnzuur
    • Acide 2,4,5-trichloro phenoxyacetique
    • (2,4,5-Trichlor-phenoxy)-essigsaeure
    • Acido (2,4,5-tricloro-fenossi)-acetico
    • 9Q963S4YMX
    • CHEMBL194458
    • NSC430
    • DTXSID5021388
    • CHEBI:27903
    • Trichlorophenoxyacetic acid
    • NSC-430
    • MFCD00004301
    • 2,4,5-TrichlorophenoxyaceticAcid-13C6
    • Visko Rhap
    • Lo-vol
    • 2-[2,4,5-tris(chloranyl)phenoxy]ethanoic acid
    • T-Nox
    • DTXCID301388
    • Caswell No. 881
    • NSC 430
    • 2,4,5-trichlorophenoxyacetate
    • CAS-93-76-5
    • CCRIS 1466
    • 2,4,5-trichloro-phenoxyacetic acid
    • HSDB 1145
    • 2,4,5-T [BSI:ISO]
    • U 46
    • EINECS 202-273-3
    • RCRA waste no. U232
    • EPA Pesticide Chemical Code 082001
    • BRN 2055620
    • UNII-9Q963S4YMX
    • AI3-14656
    • Kwas 2,4,5-trojchlorofenoksyoctowy [Polish]
    • Brush Tox
    • (2,4,5-Trichloor-fenoxy)-azijnzuur [Dutch]
    • (2,4,5-Trichlor-phenoxy)-essigsaeure [German]
    • Acide 2,4,5-trichloro phenoxyacetique [French]
    • Cido (2,4,5-tricloro-fenossi)-acetico [Italian]
    • F52
    • Acido (2,4,5-tricloro-fenossi)-acetico [Italian]
    • 2,4,5-T [Chlorophenoxy herbicides]
    • Weedone 2,5-T
    • Cido (2,4,5-tricloro-fenossi)-acetico
    • Spectrum_001857
    • (2,4,5-Trichloro-Phenoxy)-Acetic Acid
    • SpecPlus_000468
    • Spectrum2_001224
    • Spectrum3_000834
    • Spectrum4_000674
    • Spectrum5_001982
    • bmse000640
    • Oprea1_711288
    • BSPBio_002387
    • KBioGR_001107
    • KBioSS_002374
    • SPECTRUM330042
    • (2,4,5(or 2,4,6)-Trichlorophenoxy)acetic acid
    • 4-06-00-00973 (Beilstein Handbook Reference)
    • MLS002207208
    • BIDD:ER0673
    • DivK1c_006564
    • SCHEMBL117704
    • SPBio_001068
    • WLN: QV1OR BG DG EG
    • Acetic acid, (2,4,5(or 2,4,6)-trichlorophenoxy)-
    • 2,5-Trichlorophenoxyacetic acid
    • Esteron brush killer (Salt/Mix)
    • KBio1_001508
    • KBio2_002370
    • KBio2_004938
    • KBio2_007506
    • KBio3_001887
    • (2,5-Trichloor-fenoxy)-azijnzuur
    • (2,5-Trichlorophenoxy)acetic acid
    • (2,5-Trichlor-phenoxy)-essigsaeure
    • 2,4,5-T [HSDB]
    • Acetic acid,4,5-trichlorophenoxy)-
    • Acide 2,5-trichloro phenoxyacetique
    • Tox21_201605
    • Tox21_302882

  • Applications

    2,4,5-Trichlorophenoxyacetic acid (CAS 93-76-5) is primarily used as a phenoxy herbicide for selective control of broadleaf weeds in agriculture and forestry. It is commonly formulated and applied in mixtures with other herbicides (often together with 2,4-D) to protect crops and manage vegetation in agricultural fields, non-crop areas, and along rights-of-way and infrastructure. In industrial and land-management settings, it may be used to control vegetation around railways, utility corridors, and roadsides. It can also serve as an intermediate or starting material in the synthesis of other phenoxyacetic acid herbicides and related organic intermediates, with usage governed by regulatory requirements. Because of toxicity concerns, its application is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 79.44
    methanol 72.26
    isopropanol 50.07
    water 0.51
    ethyl acetate 78.95
    n-propanol 66.38
    acetone 179.69
    n-butanol 53.07
    acetonitrile 47.76
    DMF 341.98
    toluene 5.39
    isobutanol 41.13
    1,4-dioxane 170.27
    methyl acetate 115.88
    THF 454.73
    2-butanone 144.69
    n-pentanol 63.05
    sec-butanol 63.42
    n-hexane 1.82
    ethylene glycol 27.85
    NMP 239.15
    cyclohexane 1.95
    DMSO 171.49
    n-butyl acetate 77.28
    n-octanol 29.6
    chloroform 11.52
    n-propyl acetate 88.82
    acetic acid 45.2
    dichloromethane 21.2
    cyclohexanone 91.43
    propylene glycol 23.1
    isopropyl acetate 59.2
    DMAc 471.43
    2-ethoxyethanol 193.21
    isopentanol 46.07
    n-heptane 6.12
    ethyl formate 53.58
    1,2-dichloroethane 24.84
    n-hexanol 44.06
    2-methoxyethanol 232.5
    isobutyl acetate 51.67
    tetrachloromethane 0.59
    n-pentyl acetate 48.54
    transcutol 254.38
    n-heptanol 28.29
    ethylbenzene 9.77
    MIBK 56.43
    2-propoxyethanol 133.56
    tert-butanol 73.31
    MTBE 99.27
    2-butoxyethanol 73.25
    propionic acid 29.35
    o-xylene 9.5
    formic acid 37.05
    diethyl ether 74.64
    m-xylene 6.61
    p-xylene 14.29
    chlorobenzene 8.01
    dimethyl carbonate 57.93
    n-octane 2.71
    formamide 89.42
    cyclopentanone 162.66
    2-pentanone 94.13
    anisole 74.65
    cyclopentyl methyl ether 96.65
    gamma-butyrolactone 154.38
    1-methoxy-2-propanol 144.58
    pyridine 60.67
    3-pentanone 77.31
    furfural 117.7
    n-dodecane 2.6
    diethylene glycol 108.33
    diisopropyl ether 20.74
    tert-amyl alcohol 82.13
    acetylacetone 108.41
    n-hexadecane 2.89
    acetophenone 74.93
    methyl propionate 87.13
    isopentyl acetate 68.27
    trichloroethylene 35.48
    n-nonanol 29.29
    cyclohexanol 42.56
    benzyl alcohol 57.6
    2-ethylhexanol 36.03
    isooctanol 24.39
    dipropyl ether 66.83
    1,2-dichlorobenzene 9.75
    ethyl lactate 50.64
    propylene carbonate 67.01
    n-methylformamide 110.57
    2-pentanol 40.0
    n-pentane 1.94
    1-propoxy-2-propanol 96.38
    1-methoxy-2-propyl acetate 100.21
    2-(2-methoxypropoxy) propanol 104.04
    mesitylene 6.49
    ε-caprolactone 92.44
    p-cymene 17.62
    epichlorohydrin 160.98
    1,1,1-trichloroethane 9.73
    2-aminoethanol 46.16
    morpholine-4-carbaldehyde 263.24
    sulfolane 123.91
    2,2,4-trimethylpentane 2.47
    2-methyltetrahydrofuran 193.23
    n-hexyl acetate 50.8
    isooctane 1.31
    2-(2-butoxyethoxy)ethanol 114.59
    sec-butyl acetate 60.52
    tert-butyl acetate 71.45
    decalin 2.38
    glycerin 46.01
    diglyme 218.74
    acrylic acid 26.83
    isopropyl myristate 30.66
    n-butyric acid 38.16
    acetyl acetate 40.51
    di(2-ethylhexyl) phthalate 28.25
    ethyl propionate 72.66
    nitromethane 124.81
    1,2-diethoxyethane 124.13
    benzonitrile 32.16
    trioctyl phosphate 21.68
    1-bromopropane 15.07
    gamma-valerolactone 197.22
    n-decanol 25.09
    triethyl phosphate 41.18
    4-methyl-2-pentanol 25.15
    propionitrile 43.73
    vinylene carbonate 50.32
    1,1,2-trichlorotrifluoroethane 85.36
    DMS 55.75
    cumene 11.34
    2-octanol 23.01
    2-hexanone 101.87
    octyl acetate 37.42
    limonene 26.48
    1,2-dimethoxyethane 341.58
    ethyl orthosilicate 40.92
    tributyl phosphate 26.86
    diacetone alcohol 96.39
    N,N-dimethylaniline 64.45
    acrylonitrile 47.09
    aniline 25.1
    1,3-propanediol 65.14
    bromobenzene 5.51
    dibromomethane 10.76
    1,1,2,2-tetrachloroethane 31.36
    2-methyl-cyclohexyl acetate 57.64
    tetrabutyl urea 55.04
    diisobutyl methanol 23.72
    2-phenylethanol 49.57
    styrene 11.56
    dioctyl adipate 48.02
    dimethyl sulfate 79.32
    ethyl butyrate 73.11
    methyl lactate 56.63
    butyl lactate 43.29
    diethyl carbonate 50.6
    propanediol butyl ether 59.59
    triethyl orthoformate 63.22
    p-tert-butyltoluene 17.22
    methyl 4-tert-butylbenzoate 65.71
    morpholine 229.07
    tert-butylamine 35.41
    n-dodecanol 21.0
    dimethoxymethane 236.47
    ethylene carbonate 43.26
    cyrene 109.8
    2-ethoxyethyl acetate 74.43
    2-ethylhexyl acetate 56.56
    1,2,4-trichlorobenzene 16.67
    4-methylpyridine 57.62
    dibutyl ether 48.91
    2,6-dimethyl-4-heptanol 23.72
    DEF 140.94
    dimethyl isosorbide 168.68
    tetrachloroethylene 14.7
    eugenol 68.64
    triacetin 62.58
    span 80 58.47
    1,4-butanediol 38.61
    1,1-dichloroethane 15.22
    2-methyl-1-pentanol 54.55
    methyl formate 94.4
    2-methyl-1-butanol 50.04
    n-decane 3.86
    butyronitrile 40.18
    3,7-dimethyl-1-octanol 30.88
    1-chlorooctane 14.43
    1-chlorotetradecane 7.48
    n-nonane 3.48
    undecane 3.11
    tert-butylcyclohexane 2.65
    cyclooctane 1.18
    cyclopentanol 68.47
    tetrahydropyran 112.5
    tert-amyl methyl ether 91.88
    2,5,8-trioxanonane 170.51
    1-hexene 11.56
    2-isopropoxyethanol 128.51
    2,2,2-trifluoroethanol 25.52
    methyl butyrate 92.69

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction