24,26-Cyclocholesterol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    84871-07-8

    Molecular formula
    C27H44O

    SMILES
    C[C@H]1C[C@@H]1CC[C@@H](C)[C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3CC=C5[C@@]4(CC[C@@H](C5)O)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 77.24%
    Sandalwood 53.93%
    Sweet 42.9%
    Amber 42.11%
    Balsamic 41.59%
    Waxy 36.28%
    Dry 35.5%
    Musk 33.19%
    Floral 32.73%
    Clean 30.56%

     

    Flavor
    Woody 38.03%
    Wood 32.07%
    Herb 31.02%
    Waxy 27.66%
    Fir needle 26.05%
    Sweet 25.32%
    Fruity 25.1%
    Herbal 25.01%
    Spice 23.62%
    Fruit 23.17%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    8.0

    pKa est.
    8.04 (weak base)

    Molecular weight
    384.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    444°C

    Flash point

    • 189.01 ˚C est.

  • Synonyms

    • 24,26-Cyclocholesterol
    • (25S)-24S,26-cyclocholest-5-en-3beta-ol
    • RefChem:910342
    • 24-Norchol-5-en-3-ol, 23-(2-methylcyclopropyl)-, (3beta)-
    • 84871-07-8
    • (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-4-[(1S,2S)-2-methylcyclopropyl]butan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
    • CHEBI:173047
    • LMST01110008
    • 84871-07-8

  • Applications

    24,26-Cyclocholesterol (CAS 84871-07-8) is often used as an intermediate or starting material in steroid and sterol synthesis for research and pharmaceutical development; it can be used as a reference standard in lipid analysis and lipidomics; it is employed as a research chemical for membrane biology studies and sterol-related lipid organization; and it may be used as a precursor or building block for steroid synthesis in R&D projects and scientific studies, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 15.2
    methanol 3.68
    isopropanol 13.93
    water 0.04
    ethyl acetate 20.78
    n-propanol 16.76
    acetone 19.04
    n-butanol 23.65
    acetonitrile 3.27
    DMF 7.64
    toluene 35.98
    isobutanol 12.69
    1,4-dioxane 42.98
    methyl acetate 9.06
    THF 67.69
    2-butanone 19.17
    n-pentanol 11.78
    sec-butanol 7.94
    n-hexane 1.72
    ethylene glycol 0.54
    NMP 9.74
    cyclohexane 4.43
    DMSO 5.23
    n-butyl acetate 25.4
    n-octanol 8.76
    chloroform 41.54
    n-propyl acetate 14.11
    acetic acid 5.47
    dichloromethane 22.69
    cyclohexanone 32.59
    propylene glycol 1.21
    isopropyl acetate 29.66
    DMAc 15.51
    2-ethoxyethanol 17.26
    isopentanol 22.47
    n-heptane 3.04
    ethyl formate 4.98
    1,2-dichloroethane 16.31
    n-hexanol 18.52
    2-methoxyethanol 19.11
    isobutyl acetate 16.97
    tetrachloromethane 8.37
    n-pentyl acetate 25.79
    transcutol 121.85
    n-heptanol 14.58
    ethylbenzene 12.34
    MIBK 30.12
    2-propoxyethanol 43.71
    tert-butanol 12.1
    MTBE 23.14
    2-butoxyethanol 36.03
    propionic acid 4.93
    o-xylene 17.35
    formic acid 1.32
    diethyl ether 34.2
    m-xylene 23.82
    p-xylene 12.66
    chlorobenzene 19.05
    dimethyl carbonate 6.53
    n-octane 0.92
    formamide 2.15
    cyclopentanone 28.34
    2-pentanone 27.35
    anisole 24.79
    cyclopentyl methyl ether 30.54
    gamma-butyrolactone 18.1
    1-methoxy-2-propanol 23.62
    pyridine 29.58
    3-pentanone 19.42
    furfural 16.07
    n-dodecane 0.57
    diethylene glycol 13.6
    diisopropyl ether 14.53
    tert-amyl alcohol 7.23
    acetylacetone 30.01
    n-hexadecane 0.71
    acetophenone 19.33
    methyl propionate 14.1
    isopentyl acetate 35.47
    trichloroethylene 31.04
    n-nonanol 11.26
    cyclohexanol 13.11
    benzyl alcohol 13.74
    2-ethylhexanol 14.71
    isooctanol 14.09
    dipropyl ether 25.37
    1,2-dichlorobenzene 16.9
    ethyl lactate 6.77
    propylene carbonate 11.52
    n-methylformamide 2.98
    2-pentanol 13.13
    n-pentane 3.0
    1-propoxy-2-propanol 35.82
    1-methoxy-2-propyl acetate 49.99
    2-(2-methoxypropoxy) propanol 30.98
    mesitylene 14.72
    ε-caprolactone 27.77
    p-cymene 12.51
    epichlorohydrin 28.98
    1,1,1-trichloroethane 18.99
    2-aminoethanol 2.49
    morpholine-4-carbaldehyde 22.23
    sulfolane 14.15
    2,2,4-trimethylpentane 1.68
    2-methyltetrahydrofuran 29.26
    n-hexyl acetate 25.41
    isooctane 2.15
    2-(2-butoxyethoxy)ethanol 44.77
    sec-butyl acetate 16.1
    tert-butyl acetate 36.95
    decalin 2.34
    glycerin 2.53
    diglyme 77.41
    acrylic acid 3.12
    isopropyl myristate 12.25
    n-butyric acid 17.14
    acetyl acetate 16.0
    di(2-ethylhexyl) phthalate 12.91
    ethyl propionate 14.92
    nitromethane 6.41
    1,2-diethoxyethane 41.96
    benzonitrile 11.25
    trioctyl phosphate 8.2
    1-bromopropane 15.29
    gamma-valerolactone 46.81
    n-decanol 7.41
    triethyl phosphate 12.89
    4-methyl-2-pentanol 13.67
    propionitrile 7.32
    vinylene carbonate 11.34
    1,1,2-trichlorotrifluoroethane 15.32
    DMS 14.03
    cumene 9.41
    2-octanol 7.96
    2-hexanone 15.55
    octyl acetate 12.75
    limonene 13.56
    1,2-dimethoxyethane 31.52
    ethyl orthosilicate 16.15
    tributyl phosphate 8.25
    diacetone alcohol 25.68
    N,N-dimethylaniline 17.28
    acrylonitrile 5.37
    aniline 21.57
    1,3-propanediol 9.91
    bromobenzene 22.24
    dibromomethane 18.83
    1,1,2,2-tetrachloroethane 24.72
    2-methyl-cyclohexyl acetate 22.53
    tetrabutyl urea 11.8
    diisobutyl methanol 13.2
    2-phenylethanol 24.92
    styrene 12.37
    dioctyl adipate 16.09
    dimethyl sulfate 7.08
    ethyl butyrate 23.2
    methyl lactate 6.07
    butyl lactate 18.24
    diethyl carbonate 14.39
    propanediol butyl ether 16.81
    triethyl orthoformate 25.82
    p-tert-butyltoluene 12.42
    methyl 4-tert-butylbenzoate 29.98
    morpholine 38.91
    tert-butylamine 9.68
    n-dodecanol 4.88
    dimethoxymethane 26.94
    ethylene carbonate 11.82
    cyrene 17.48
    2-ethoxyethyl acetate 42.31
    2-ethylhexyl acetate 29.18
    1,2,4-trichlorobenzene 20.68
    4-methylpyridine 28.64
    dibutyl ether 13.41
    2,6-dimethyl-4-heptanol 13.2
    DEF 16.97
    dimethyl isosorbide 44.39
    tetrachloroethylene 18.09
    eugenol 27.3
    triacetin 26.93
    span 80 22.33
    1,4-butanediol 2.81
    1,1-dichloroethane 16.64
    2-methyl-1-pentanol 12.12
    methyl formate 2.12
    2-methyl-1-butanol 15.52
    n-decane 1.39
    butyronitrile 11.95
    3,7-dimethyl-1-octanol 12.39
    1-chlorooctane 5.56
    1-chlorotetradecane 2.0
    n-nonane 1.12
    undecane 0.84
    tert-butylcyclohexane 2.12
    cyclooctane 2.03
    cyclopentanol 8.58
    tetrahydropyran 45.78
    tert-amyl methyl ether 14.2
    2,5,8-trioxanonane 46.54
    1-hexene 5.25
    2-isopropoxyethanol 17.01
    2,2,2-trifluoroethanol 2.63
    methyl butyrate 14.09

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction