2,4-Dihydroxybenzophenone

Overview IFRA Request a quote

  • Identifiers

    CAS number
    131-56-6

    Molecular formula
    C13H10O3

    SMILES
    C1=CC=C(C=C1)C(=O)C2=C(C=C(C=C2)O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Phenolic 63.83%
    Sweet 48.23%
    Balsamic 45.46%
    Bitter 38.91%
    Medicinal 38.6%
    Odorless 35.42%
    Spicy 34.24%
    Vanilla 31.19%
    Aromatic 29.84%
    Fruity 29.72%

     

    Flavor
    Bitter 87.79%
    Odorless 27.42%
    Nitrile 21.94%
    Lovage 21.47%
    Very strong 21.41%
    Mild 21.34%
    Phenolic 21.25%
    Indole 21.02%
    Urine 20.77%
    Moth ball 20.63%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.2

    pKa est.
    9.88 (weak base)

    Molecular weight
    214.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 144 °C

    Boiling point

    • BP: 194 °C at 1 mm Hg

    Flash point

    • 188.24 ˚C est.

    Solubility expt.

    • Practically insoluble in cold water
    • Insoluble in water
    • Easily soluble in alcohol, ether, glacial acetic acid; scarcely soluble in cold benzene
    • Soluble in ethanol, methanol, methyl ethyl ketone, and ethyl acetate

  • Synonyms

    • 2,4-DIHYDROXYBENZOPHENONE
    • 131-56-6
    • Benzoresorcinol
    • Resbenzophenone
    • Inhibitor DHBP
    • Uvinul 400
    • Advastab 48
    • Uvistat 12
    • Quinsorb 010
    • Syntase 100
    • Methanone, (2,4-dihydroxyphenyl)phenyl-
    • Uvinol 400
    • Eastman Inhibitor DHPB
    • 4-Benzoyl resorcinol
    • Dastib 263
    • (2,4-Dihydroxyphenyl)phenylmethanone
    • (2,4-dihydroxyphenyl)-phenyl-methanone
    • USAF DO-28
    • USAF ND-54
    • UV 12
    • 2,4-Dihydroxybenzofenon
    • DTXSID8022406
    • (2,4-dihydroxyphenyl)-phenylmethanone
    • 2,4-DHB
    • LJ54R4Z029
    • NSC-38555
    • DTXCID402406
    • DHBP cpd
    • RefChem:82459
    • 205-029-4
    • Benzophenone-1
    • (2,4-dihydroxyphenyl)(phenyl)methanone
    • 4-Benzoylresorcinol
    • benzophenone 1
    • Benzophenone, 2,4-dihydroxy-
    • UF 1
    • NSC 38555
    • (2,4-Dihydroxy-phenyl)-phenyl-methanone
    • MFCD00002277
    • 2,4-dihydroxy benzophenone
    • MLS000774789
    • [2,4-bis(oxidanyl)phenyl]-phenyl-methanone
    • HHB
    • SMR000365551
    • Benzophenone,4-dihydroxy-
    • WLN: QR CQ DVR
    • 2,4 inverted exclamation marka-Dihydroxybenzophenone
    • 2,4-dihydroxyphenyl phenyl ketone
    • Methanone,4-dihydroxyphenyl)phenyl-
    • 2,4-Dihydroxybenzofenon [Czech]
    • 4-benzoylbenzene-1,3-diol
    • CAS-131-56-6
    • HSDB 5617
    • EINECS 205-029-4
    • BRN 1311566
    • UNII-LJ54R4Z029
    • UV-0
    • CUT
    • Eastman inhibitor DHBP
    • 2,4dihydroxybenzophenone
    • Enamine_001926
    • OXYBENZONE_met023
    • 4,6-Dihydroxybenzophenone
    • 2,4-dihydroxy-benzophenone
    • 2,4-dihydroxybenzophe none
    • EC 205-029-4
    • cid_8572
    • BENZORESORCINOL [MI]
    • CHEMBL1392
    • 2,4-dihydroxybenzo- phenone
    • Oprea1_840620
    • SCHEMBL39681
    • hsp90_163
    • BIDD:ER0039
    • orb1299905
    • orb3025694
    • SCHEMBL8372891
    • SCHEMBL28008205
    • SCHEMBL28988579
    • SCHEMBL29351647
    • BDBM51223
    • CHEBI:34240
    • MSK3447
    • NSC5358
    • 2,4-Dihydroxybenzophenone, 99%
    • 2,4-Dihydroxybenzophenone(UV-0)
    • HMS1399H12
    • HMS2771P10
    • BB_SC-06748
    • NSC-5358
    • NSC38555
    • Tox21_201285
    • Tox21_302865
    • BBL013153
    • SBB063282
    • STL163951
    • (2,4-dihydroxyphenyl)phenyl-methanone
    • AKOS001019876
    • MSK3447-1000A
    • CS-W014939
    • FD40440
    • HY-W014223
    • NCGC00246026-01
    • NCGC00246026-02
    • NCGC00256606-01
    • NCGC00258837-01
    • 2,4-DIHYDROXYBENZOPHENONE [HSDB]
    • 92092-63-2
    • AC-11241
    • DS-15473
    • MSK3447-1000
    • D0573
    • NS00001568
    • ST50308028
    • EN300-16886
    • 135D566
    • AE-641/01968047
    • F236844
    • Q209209
    • SR-01000388910
    • SR-01000388910-1
    • Z56812729
    • 2,4-Dihydroxybenzophenone Solution in Acetonitrile, 1000?g/mL
    • 2,4-Dihydroxybenzophenone Solution in Acetonitrile, 1000ug/mL
    • 131-56-6

  • Applications

    2,4-Dihydroxybenzophenone (CAS 131-56-6) is primarily used as an intermediate in the synthesis of UV-stabilizing additives and antioxidants for polymers and coatings. It also serves as a building block for specialty dyes and other fine chemicals, including pharmaceutical precursors. In formulation work, it may be incorporated into UV-curable coatings and inks to improve durability and lightfastness, and it can act as a precursor for photoactive materials used in electronics or as a stabilizer or crosslinking component in adhesives and sealants. It may also serve as a starting material for further derivatization in industrial syntheses.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 117.94
    methanol 130.42
    isopropanol 96.89
    water 0.13
    ethyl acetate 108.83
    n-propanol 78.89
    acetone 335.45
    n-butanol 48.57
    acetonitrile 104.09
    DMF 594.71
    toluene 8.69
    isobutanol 45.41
    1,4-dioxane 205.55
    methyl acetate 139.02
    THF 591.39
    2-butanone 188.19
    n-pentanol 39.61
    sec-butanol 50.62
    n-hexane 0.1
    ethylene glycol 76.6
    NMP 238.73
    cyclohexane 0.15
    DMSO 1345.87
    n-butyl acetate 65.47
    n-octanol 25.32
    chloroform 3.57
    n-propyl acetate 71.9
    acetic acid 117.6
    dichloromethane 2.7
    cyclohexanone 147.19
    propylene glycol 147.39
    isopropyl acetate 80.68
    DMAc 401.58
    2-ethoxyethanol 108.19
    isopentanol 61.36
    n-heptane 0.21
    ethyl formate 67.65
    1,2-dichloroethane 11.95
    n-hexanol 40.4
    2-methoxyethanol 366.03
    isobutyl acetate 39.81
    tetrachloromethane 0.86
    n-pentyl acetate 31.83
    transcutol 546.09
    n-heptanol 26.68
    ethylbenzene 7.08
    MIBK 86.24
    2-propoxyethanol 146.3
    tert-butanol 152.44
    MTBE 56.13
    2-butoxyethanol 78.95
    propionic acid 96.73
    o-xylene 7.18
    formic acid 59.5
    diethyl ether 29.86
    m-xylene 8.51
    p-xylene 8.19
    chlorobenzene 9.28
    dimethyl carbonate 84.77
    n-octane 0.14
    formamide 238.22
    cyclopentanone 312.51
    2-pentanone 126.71
    anisole 53.01
    cyclopentyl methyl ether 76.19
    gamma-butyrolactone 328.89
    1-methoxy-2-propanol 299.98
    pyridine 73.82
    3-pentanone 62.79
    furfural 176.48
    n-dodecane 0.77
    diethylene glycol 159.86
    diisopropyl ether 11.75
    tert-amyl alcohol 81.77
    acetylacetone 226.09
    n-hexadecane 0.91
    acetophenone 58.68
    methyl propionate 105.69
    isopentyl acetate 61.79
    trichloroethylene 31.63
    n-nonanol 25.4
    cyclohexanol 44.27
    benzyl alcohol 52.38
    2-ethylhexanol 26.94
    isooctanol 25.02
    dipropyl ether 25.33
    1,2-dichlorobenzene 10.95
    ethyl lactate 65.32
    propylene carbonate 136.93
    n-methylformamide 216.87
    2-pentanol 37.71
    n-pentane 0.09
    1-propoxy-2-propanol 106.05
    1-methoxy-2-propyl acetate 106.18
    2-(2-methoxypropoxy) propanol 102.66
    mesitylene 6.6
    ε-caprolactone 125.98
    p-cymene 8.43
    epichlorohydrin 258.72
    1,1,1-trichloroethane 9.1
    2-aminoethanol 141.6
    morpholine-4-carbaldehyde 217.18
    sulfolane 446.01
    2,2,4-trimethylpentane 0.71
    2-methyltetrahydrofuran 158.45
    n-hexyl acetate 53.36
    isooctane 0.79
    2-(2-butoxyethoxy)ethanol 145.26
    sec-butyl acetate 50.07
    tert-butyl acetate 99.26
    decalin 0.71
    glycerin 207.1
    diglyme 251.1
    acrylic acid 94.24
    isopropyl myristate 26.88
    n-butyric acid 106.37
    acetyl acetate 74.91
    di(2-ethylhexyl) phthalate 25.44
    ethyl propionate 61.99
    nitromethane 359.97
    1,2-diethoxyethane 80.29
    benzonitrile 44.77
    trioctyl phosphate 21.27
    1-bromopropane 2.83
    gamma-valerolactone 307.64
    n-decanol 20.2
    triethyl phosphate 31.91
    4-methyl-2-pentanol 36.7
    propionitrile 65.33
    vinylene carbonate 89.27
    1,1,2-trichlorotrifluoroethane 183.25
    DMS 64.19
    cumene 6.93
    2-octanol 16.44
    2-hexanone 74.6
    octyl acetate 33.1
    limonene 11.37
    1,2-dimethoxyethane 208.3
    ethyl orthosilicate 27.03
    tributyl phosphate 25.28
    diacetone alcohol 189.93
    N,N-dimethylaniline 30.45
    acrylonitrile 101.97
    aniline 32.69
    1,3-propanediol 182.83
    bromobenzene 5.51
    dibromomethane 1.56
    1,1,2,2-tetrachloroethane 33.24
    2-methyl-cyclohexyl acetate 40.62
    tetrabutyl urea 36.64
    diisobutyl methanol 21.96
    2-phenylethanol 48.35
    styrene 8.19
    dioctyl adipate 41.84
    dimethyl sulfate 145.47
    ethyl butyrate 50.88
    methyl lactate 124.99
    butyl lactate 48.4
    diethyl carbonate 39.23
    propanediol butyl ether 99.08
    triethyl orthoformate 39.16
    p-tert-butyltoluene 9.31
    methyl 4-tert-butylbenzoate 59.71
    morpholine 264.11
    tert-butylamine 41.38
    n-dodecanol 15.58
    dimethoxymethane 264.06
    ethylene carbonate 74.05
    cyrene 91.22
    2-ethoxyethyl acetate 62.53
    2-ethylhexyl acetate 40.4
    1,2,4-trichlorobenzene 19.92
    4-methylpyridine 61.51
    dibutyl ether 26.78
    2,6-dimethyl-4-heptanol 21.96
    DEF 117.76
    dimethyl isosorbide 137.82
    tetrachloroethylene 13.67
    eugenol 65.43
    triacetin 69.26
    span 80 70.18
    1,4-butanediol 44.54
    1,1-dichloroethane 6.25
    2-methyl-1-pentanol 43.29
    methyl formate 145.16
    2-methyl-1-butanol 44.21
    n-decane 0.84
    butyronitrile 55.97
    3,7-dimethyl-1-octanol 29.71
    1-chlorooctane 7.45
    1-chlorotetradecane 4.15
    n-nonane 0.49
    undecane 0.81
    tert-butylcyclohexane 1.05
    cyclooctane 0.1
    cyclopentanol 75.62
    tetrahydropyran 94.2
    tert-amyl methyl ether 39.03
    2,5,8-trioxanonane 176.35
    1-hexene 1.59
    2-isopropoxyethanol 83.68
    2,2,2-trifluoroethanol 43.19
    methyl butyrate 81.34

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction