2,4-Diethylthiazole

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  • Identifiers

    CAS number
    32272-49-4

    Molecular formula
    C7H11NS

    SMILES
    CCC1=CSC(=N1)CC

    Safety labels

  • Odor profile

    Fragrance
    Green 92.2%
    Vegetable 68.06%
    Nutty 64.34%
    Meaty 50.3%
    Roasted 47.5%
    Sulfurous 46.06%
    Earthy 46.02%
    Cocoa 38.29%
    Tomato 38.03%
    Musty 35.96%

     

    Flavor
    Green 85.53%
    Nutty 62.38%
    Vegetable 47.8%
    Earthy 42.92%
    Raw 35.05%
    Roasted 33.16%
    Pepper 32.91%
    Tomato 31.49%
    Fatty 27.6%
    Fruit 27.52%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.6

    pKa est.
    6.66 (neutral)

    Molecular weight
    141.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point est.
    174°C

    Flash point

    • 57.53 ˚C est.

  • Synonyms

    • 2,4-Diethylthiazole
    • 2,4-Diethyl-1,3-thiazole
    • Thiazole, 2,4-diethyl-
    • DTXSID7067665
    • RefChem:82413
    • DTXCID4038473
    • IAEOVWDULPWPSJ-UHFFFAOYSA-N
    • 32272-49-4
    • AQ4XVQ2Z6T
    • SCHEMBL128234
    • SCHEMBL2256127
    • SCHEMBL4870221
    • SCHEMBL14723360
    • 2,4-Diethyl-1,3-thiazole #
    • AKOS006370482
    • 32272-49-4

  • Applications

    2,4-Diethylthiazole (CAS 32272-49-4) is a heteroaromatic thiazole compound primarily used as an odorant and fragrance ingredient in the fragrance and flavor industries. It is also considered an intermediate for the synthesis of other thiazole-containing compounds used in industrial chemical manufacturing. In cosmetics and personal care, it may be incorporated as a fragrance component. In cleaning and household products, it can serve to impart or enhance scent. Additionally, it may be used in coatings and printing inks as a fragrance additive or intermediate for broader industrial applications, subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 251.8
    methanol 274.93
    isopropanol 206.54
    water 0.54
    ethyl acetate 388.19
    n-propanol 236.66
    acetone 615.84
    n-butanol 256.21
    acetonitrile 329.9
    DMF 891.83
    toluene 495.95
    isobutanol 220.13
    1,4-dioxane 722.77
    methyl acetate 425.04
    THF 1030.1
    2-butanone 578.91
    n-pentanol 233.73
    sec-butanol 238.3
    n-hexane 118.31
    ethylene glycol 64.1
    NMP 1048.21
    cyclohexane 201.44
    DMSO 779.09
    n-butyl acetate 613.52
    n-octanol 279.89
    chloroform 1833.08
    n-propyl acetate 397.58
    acetic acid 234.3
    dichloromethane 1819.7
    cyclohexanone 991.15
    propylene glycol 79.93
    isopropyl acetate 284.78
    DMAc 791.4
    2-ethoxyethanol 323.61
    isopentanol 239.42
    n-heptane 154.18
    ethyl formate 309.47
    1,2-dichloroethane 970.7
    n-hexanol 357.19
    2-methoxyethanol 366.48
    isobutyl acetate 311.98
    tetrachloromethane 465.33
    n-pentyl acetate 445.46
    transcutol 766.63
    n-heptanol 239.5
    ethylbenzene 357.62
    MIBK 318.02
    2-propoxyethanol 462.3
    tert-butanol 263.83
    MTBE 366.73
    2-butoxyethanol 324.49
    propionic acid 221.3
    o-xylene 363.19
    formic acid 50.27
    diethyl ether 361.37
    m-xylene 354.05
    p-xylene 497.82
    chlorobenzene 829.72
    dimethyl carbonate 229.47
    n-octane 87.9
    formamide 86.42
    cyclopentanone 1082.79
    2-pentanone 457.56
    anisole 518.8
    cyclopentyl methyl ether 510.43
    gamma-butyrolactone 981.23
    1-methoxy-2-propanol 309.91
    pyridine 870.23
    3-pentanone 442.61
    furfural 949.92
    n-dodecane 78.7
    diethylene glycol 259.63
    diisopropyl ether 169.4
    tert-amyl alcohol 273.26
    acetylacetone 557.19
    n-hexadecane 89.87
    acetophenone 553.24
    methyl propionate 364.92
    isopentyl acetate 505.27
    trichloroethylene 1887.44
    n-nonanol 248.92
    cyclohexanol 333.48
    benzyl alcohol 380.34
    2-ethylhexanol 317.64
    isooctanol 215.78
    dipropyl ether 403.41
    1,2-dichlorobenzene 821.72
    ethyl lactate 189.64
    propylene carbonate 612.17
    n-methylformamide 281.8
    2-pentanol 188.94
    n-pentane 98.22
    1-propoxy-2-propanol 361.16
    1-methoxy-2-propyl acetate 440.47
    2-(2-methoxypropoxy) propanol 352.3
    mesitylene 266.19
    ε-caprolactone 731.41
    p-cymene 306.64
    epichlorohydrin 1025.0
    1,1,1-trichloroethane 1068.04
    2-aminoethanol 110.55
    morpholine-4-carbaldehyde 886.05
    sulfolane 1232.07
    2,2,4-trimethylpentane 74.48
    2-methyltetrahydrofuran 760.3
    n-hexyl acetate 579.72
    isooctane 58.09
    2-(2-butoxyethoxy)ethanol 399.44
    sec-butyl acetate 279.7
    tert-butyl acetate 335.46
    decalin 141.13
    glycerin 123.32
    diglyme 775.57
    acrylic acid 216.42
    isopropyl myristate 307.42
    n-butyric acid 325.96
    acetyl acetate 311.01
    di(2-ethylhexyl) phthalate 280.32
    ethyl propionate 348.07
    nitromethane 432.78
    1,2-diethoxyethane 520.32
    benzonitrile 714.65
    trioctyl phosphate 212.55
    1-bromopropane 601.02
    gamma-valerolactone 1039.94
    n-decanol 199.25
    triethyl phosphate 250.23
    4-methyl-2-pentanol 139.54
    propionitrile 373.77
    vinylene carbonate 642.89
    1,1,2-trichlorotrifluoroethane 569.51
    DMS 448.79
    cumene 265.36
    2-octanol 218.44
    2-hexanone 477.67
    octyl acetate 349.94
    limonene 419.54
    1,2-dimethoxyethane 706.24
    ethyl orthosilicate 236.5
    tributyl phosphate 260.3
    diacetone alcohol 297.05
    N,N-dimethylaniline 441.33
    acrylonitrile 458.62
    aniline 402.87
    1,3-propanediol 170.64
    bromobenzene 1036.95
    dibromomethane 1224.14
    1,1,2,2-tetrachloroethane 1326.34
    2-methyl-cyclohexyl acetate 433.87
    tetrabutyl urea 366.91
    diisobutyl methanol 193.79
    2-phenylethanol 420.71
    styrene 470.62
    dioctyl adipate 384.55
    dimethyl sulfate 368.64
    ethyl butyrate 456.4
    methyl lactate 181.88
    butyl lactate 293.87
    diethyl carbonate 324.84
    propanediol butyl ether 289.78
    triethyl orthoformate 312.45
    p-tert-butyltoluene 277.48
    methyl 4-tert-butylbenzoate 447.21
    morpholine 634.53
    tert-butylamine 213.11
    n-dodecanol 168.34
    dimethoxymethane 539.82
    ethylene carbonate 497.54
    cyrene 390.33
    2-ethoxyethyl acetate 484.47
    2-ethylhexyl acetate 472.93
    1,2,4-trichlorobenzene 877.77
    4-methylpyridine 960.68
    dibutyl ether 427.32
    2,6-dimethyl-4-heptanol 193.79
    DEF 558.94
    dimethyl isosorbide 705.55
    tetrachloroethylene 911.51
    eugenol 437.55
    triacetin 497.41
    span 80 371.57
    1,4-butanediol 116.08
    1,1-dichloroethane 907.26
    2-methyl-1-pentanol 257.51
    methyl formate 264.47
    2-methyl-1-butanol 236.03
    n-decane 114.38
    butyronitrile 428.38
    3,7-dimethyl-1-octanol 274.19
    1-chlorooctane 318.34
    1-chlorotetradecane 163.52
    n-nonane 117.23
    undecane 91.68
    tert-butylcyclohexane 124.25
    cyclooctane 95.3
    cyclopentanol 385.23
    tetrahydropyran 660.04
    tert-amyl methyl ether 313.53
    2,5,8-trioxanonane 588.02
    1-hexene 293.55
    2-isopropoxyethanol 262.62
    2,2,2-trifluoroethanol 105.31
    methyl butyrate 480.6

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction