2,4-Di-tert-butylphenol
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Identifiers
CAS number
96-76-4Molecular formula
C14H22OSMILES
CC(C)(C)C1=CC(=C(C=C1)O)C(C)(C)C
Safety labels
Corrosive
Irritant
Health
Environmental -
Odor profile
Fragrance Phenolic 63.83% Leathery 53.66% Woody 48.41% Medicinal 39.72% Dry 38.72% Spicy 38.7% Camphoreous 38.22% Smoky 37.54% Burnt 33.47% Animal 32.15% Flavor Phenolic 46.34% Camphor 43.33% Musty 35.62% Mild 29.79% Woody 27.76% Leather 27.26% Medicinal 26.17% Creosote 22.84% Spice 21.92% Thymol 21.81% Odor impact est.
Medium -
Properties
XLogP3-AA
4.9pKa est.
8.85 (weak base)Molecular weight
206.32 g/molVapor pressure est.
- hPa @ 20°C
- hPa @ 25°C
Evaporation rate
SlowMelting point expt.
- 56.5 °C
Boiling point
- 263.5 °C
- 263.00 to 264.00 °C. @ 760.00 mm Hg
Flash point
- 123.04 ˚C est.
Solubility expt.
- In water, 35 mg/L at 25 °C
- Slightly soluble in carbon tetrachloride; insoluble in alkali
- 0.035 mg/mL at 25 °C
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Synonyms
- 2,4-Di-tert-butylphenol
- 96-76-4
- 2,4-DI-T-BUTYLPHENOL
- Antioxidant No. 33
- Prodox 146
- 1-Hydroxy-2,4-di-tert-butylbenzene
- Phenol, 2,4-di-tert-butyl-
- 2,4-ditert-butylphenol
- Phenol, 2,4-bis(1,1-dimethylethyl)-
- 2,4-bis(tert-butyl)phenol
- Prodox 146A-85X
- 2,4-Di-tert-butyl-phenol
- 2,4-tert-butylphenol
- 2,4-Bis(1,1-dimethylethyl)phenol
- MFCD00008828
- NSC 174502
- UNII-FOB94G6HZT
- FOB94G6HZT
- EINECS 202-532-0
- Phenol, 2,4-di(1,1-dimethylethyl)-
- BRN 1910383
- 2,4-DTBP
- DTXSID2026602
- 2,4-Di-tert-butylhydroxybenzene
- 2,4-bis(1,1-dimethylethyl)-phenol
- 2,4-Bis(1,1'-dimethylethyl)phenol
- AGIDOL 10
- 2,4-di-tert-butyl phenol
- NSC-174502
- 2,4-di~{tert}-butylphenol
- CHEMBL29873
- DTXCID606602
- CHEBI:89188
- HSDB 8453
- EC 202-532-0
- 1-Hydroxy-2, 4-di-tert-butylbenzene
- CAS-96-76-4
- 2,4-ditert-butyl-phenol
- Antioxidant No 33
- 2,4-ditertbutylphenol
- 2,4-di-tertbutylphenol
- 2,4di-tert-butylphenol
- Prodox 146A85X
- ,4-Di-tert-butylphenol
- Phenol, 2,4ditertbutyl
- 2,4-di-t-butyl-phenol
- 2,4Bis(tertbutyl)phenol
- 2,4-di-tert.butylphenol
- 2,4-di-tertbutyl phenol
- 2,4-ditert-butyl phenol
- 2,4-ditertiarybutylphenol
- Phenol,4-di-tert-butyl-
- 2,4-Di-tert.-butylphenol
- 2,4Ditertbutylhydroxybenzene
- 2,4-ditertiary-butyl phenol
- 1Hydroxy2,4ditertbutylbenzene
- SCHEMBL109921
- 2,4Bis(1,1dimetiletil)fenolo
- 2,4Bis(1,1dimethylethyl)phenol
- MSK8731
- 2,4-Di-tert-butylphenol, 99%
- Phenol, 2,4di(1,1dimethylethyl)
- BCP24012
- HY-W014589R
- Phenol, 2,4bis(1,1dimethylethyl)
- Phenol,4-bis(1,1-dimethylethyl)-
- Tox21_202320
- Tox21_300114
- 2,4-Di-tert-butylphenol (Standard)
- BDBM50409544
- NSC174502
- Phenol,2,4-Bis(1,1-dimethylethyl)
- AKOS003669719
- 1ST8731
- CS-W015305
- HY-W014589
- NCGC00164059-01
- NCGC00164059-02
- NCGC00164059-03
- NCGC00254167-01
- NCGC00259869-01
- AS-13983
- MSK8731-1000
- PD158314
- 2,4-Ditert-butylphenol (ACD/Name 4.0)
- WLN: 1X1&1&R BQ CX1&1&1
- D0229
- NS00010683
- EN300-20927
- 1ST8731-1000
- E76999
- 4-(2-methylbutan-2-yl)-2-(prop-2-en-1-yl)phenol
- Q26840829
- 2,4-Di-tert-butylphenol 100 microg/mL in Acetonitrile
- F0001-2302
- 2,4-Di-tert-butylphenol Solution in Acetonitrile, 1000?g/mL
- 2,4-Di-tert-butylphenol Solution in Acetonitrile, 1000mug/mL
- (2S)-N-[(1S)-2-[[(1S)-2-[[(1S)-2-[[(1S)-2-[[2-[[(1S)-1-[[(1S)-4-amino-1-[(2S)-2-[(2-amino-2-oxo-ethyl)carbamoyl]pyrrolidine-1-carbonyl]-4-oxo-butyl]carbamoyl]-3-methyl-butyl]amino]-2-oxo-ethyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]amino]-1-(hydro
- 202-532-0
- UGW
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Applications
2,4-Di-tert-butylphenol (CAS 96-76-4) is widely used as a hindered phenolic antioxidant and stabilizer in polymers, rubbers, and related materials to prevent oxidation during processing and in service life. In practice, typical use areas include: (1) antioxidant stabilizer for polymers and elastomers (polyolefins, synthetic rubber); (2) additive for lubricants and oils to inhibit oxidative degradation; (3) stabilizer or antioxidant additive in coatings, inks, and adhesives formulations; (4) stabilizer for fuels and other petroleum products; and (5) as an intermediate or precursor in the synthesis of other antioxidants or stabilizers.
gpt-5-nano
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Solubility @25˚C
Solvent Solubility (g/L) ethanol 155.73 methanol 98.41 isopropanol 159.76 water 0.19 ethyl acetate 223.91 n-propanol 170.18 acetone 278.56 n-butanol 168.9 acetonitrile 208.79 DMF 419.98 toluene 187.22 isobutanol 144.09 1,4-dioxane 469.27 methyl acetate 222.13 THF 1074.97 2-butanone 294.04 n-pentanol 133.4 sec-butanol 170.47 n-hexane 96.23 ethylene glycol 19.39 NMP 560.65 cyclohexane 119.46 DMSO 189.67 n-butyl acetate 326.11 n-octanol 162.76 chloroform 572.71 n-propyl acetate 193.86 acetic acid 117.65 dichloromethane 418.96 cyclohexanone 456.92 propylene glycol 64.36 isopropyl acetate 168.32 DMAc 332.03 2-ethoxyethanol 123.53 isopentanol 153.96 n-heptane 123.56 ethyl formate 173.04 1,2-dichloroethane 242.29 n-hexanol 308.57 2-methoxyethanol 197.51 isobutyl acetate 170.0 tetrachloromethane 101.23 n-pentyl acetate 183.84 transcutol 288.9 n-heptanol 170.01 ethylbenzene 154.65 MIBK 170.4 2-propoxyethanol 323.02 tert-butanol 245.46 MTBE 245.62 2-butoxyethanol 191.58 propionic acid 131.56 o-xylene 136.84 formic acid 24.59 diethyl ether 204.28 m-xylene 161.99 p-xylene 213.15 chlorobenzene 236.96 dimethyl carbonate 101.5 n-octane 47.31 formamide 54.2 cyclopentanone 666.28 2-pentanone 234.01 anisole 245.99 cyclopentyl methyl ether 375.76 gamma-butyrolactone 640.31 1-methoxy-2-propanol 215.72 pyridine 371.7 3-pentanone 191.81 furfural 418.89 n-dodecane 35.86 diethylene glycol 127.29 diisopropyl ether 102.26 tert-amyl alcohol 217.04 acetylacetone 252.47 n-hexadecane 40.31 acetophenone 218.95 methyl propionate 201.19 isopentyl acetate 316.27 trichloroethylene 475.48 n-nonanol 147.73 cyclohexanol 205.39 benzyl alcohol 148.47 2-ethylhexanol 239.08 isooctanol 140.63 dipropyl ether 280.82 1,2-dichlorobenzene 214.62 ethyl lactate 108.29 propylene carbonate 416.6 n-methylformamide 150.07 2-pentanol 142.62 n-pentane 67.96 1-propoxy-2-propanol 298.86 1-methoxy-2-propyl acetate 286.89 2-(2-methoxypropoxy) propanol 194.05 mesitylene 117.67 ε-caprolactone 402.04 p-cymene 155.1 epichlorohydrin 535.37 1,1,1-trichloroethane 331.38 2-aminoethanol 64.89 morpholine-4-carbaldehyde 434.14 sulfolane 603.33 2,2,4-trimethylpentane 44.0 2-methyltetrahydrofuran 592.58 n-hexyl acetate 273.28 isooctane 40.72 2-(2-butoxyethoxy)ethanol 223.04 sec-butyl acetate 154.89 tert-butyl acetate 223.83 decalin 77.57 glycerin 61.57 diglyme 351.78 acrylic acid 99.77 isopropyl myristate 155.19 n-butyric acid 214.7 acetyl acetate 147.38 di(2-ethylhexyl) phthalate 128.03 ethyl propionate 186.61 nitromethane 237.99 1,2-diethoxyethane 197.87 benzonitrile 217.83 trioctyl phosphate 111.31 1-bromopropane 229.23 gamma-valerolactone 639.9 n-decanol 121.07 triethyl phosphate 136.77 4-methyl-2-pentanol 105.93 propionitrile 212.79 vinylene carbonate 310.08 1,1,2-trichlorotrifluoroethane 247.22 DMS 159.3 cumene 123.96 2-octanol 129.74 2-hexanone 215.65 octyl acetate 185.24 limonene 209.15 1,2-dimethoxyethane 316.1 ethyl orthosilicate 133.85 tributyl phosphate 117.02 diacetone alcohol 231.71 N,N-dimethylaniline 194.37 acrylonitrile 206.01 aniline 178.3 1,3-propanediol 96.55 bromobenzene 261.82 dibromomethane 323.8 1,1,2,2-tetrachloroethane 401.11 2-methyl-cyclohexyl acetate 290.52 tetrabutyl urea 156.36 diisobutyl methanol 138.83 2-phenylethanol 227.9 styrene 157.2 dioctyl adipate 198.29 dimethyl sulfate 143.03 ethyl butyrate 252.06 methyl lactate 118.64 butyl lactate 154.36 diethyl carbonate 174.35 propanediol butyl ether 179.71 triethyl orthoformate 197.05 p-tert-butyltoluene 172.57 methyl 4-tert-butylbenzoate 240.82 morpholine 518.74 tert-butylamine 201.14 n-dodecanol 100.91 dimethoxymethane 266.12 ethylene carbonate 248.86 cyrene 236.81 2-ethoxyethyl acetate 170.54 2-ethylhexyl acetate 274.75 1,2,4-trichlorobenzene 254.5 4-methylpyridine 382.77 dibutyl ether 197.72 2,6-dimethyl-4-heptanol 138.83 DEF 228.5 dimethyl isosorbide 444.62 tetrachloroethylene 198.64 eugenol 201.74 triacetin 184.66 span 80 230.3 1,4-butanediol 45.71 1,1-dichloroethane 307.99 2-methyl-1-pentanol 127.1 methyl formate 133.93 2-methyl-1-butanol 148.15 n-decane 56.46 butyronitrile 249.6 3,7-dimethyl-1-octanol 151.7 1-chlorooctane 147.53 1-chlorotetradecane 75.2 n-nonane 56.53 undecane 44.29 tert-butylcyclohexane 80.29 cyclooctane 54.6 cyclopentanol 262.19 tetrahydropyran 528.93 tert-amyl methyl ether 192.42 2,5,8-trioxanonane 255.49 1-hexene 185.86 2-isopropoxyethanol 114.24 2,2,2-trifluoroethanol 46.37 methyl butyrate 242.75 Scent© AI
| Maximum acceptable concentrations in the finished product (%) | |||
|---|---|---|---|
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Category 1
Products applied to the lips
|
No restriction |
Category 7A
Rinse-off products applied to the hair with some hand contact
|
No restriction |
|
Category 2
Products applied to the axillae
|
No restriction |
Category 7B
Leave-on products applied to the hair with some hand contact
|
No restriction |
|
Category 3
Products applied to the face/body using fingertips
|
No restriction |
Category 8
Products with significant anogenital exposure
|
No restriction |
|
Category 4
Products related to fine fragrance
|
No restriction |
Category 9
Products with body and hand exposure, primarily rinse off
|
No restriction |
|
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
|
No restriction |
Category 10A
Household care products with mostly hand contact
|
No restriction |
|
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
|
No restriction |
Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
|
No restriction |
|
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
|
No restriction |
Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
|
No restriction |
|
Category 5D
Baby Creams, baby Oils and baby talc
|
No restriction |
Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
|
No restriction |
|
Category 6
Products with oral and lip exposure
|
No restriction |
Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
|
No restriction |