(23E)-Cyclosadol

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  • Identifiers

    CAS number
    25850-61-7

    Molecular formula
    C31H52O

    SMILES
    C[C@H](C/C=C(\C)/C(C)C)[C@H]1CC[C@@]2([C@@]1(CC[C@]34[C@H]2CC[C@@H]5[C@]3(C4)CC[C@@H](C5(C)C)O)C)C

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  • Odor profile

    Fragrance
    Woody 90.74%
    Sandalwood 55.86%
    Amber 50.58%
    Dry 47.14%
    Vetiver 40.39%
    Cedar 38.89%
    Balsamic 38.15%
    Waxy 34.94%
    Spicy 33.97%
    Herbal 30.5%

     

    Flavor
    Woody 67.87%
    Wood 42.6%
    Pine 33.76%
    Balsam 32.73%
    Spice 30.19%
    Camphor 29.27%
    Herb 28.31%
    Herbal 26.3%
    Terpene 26.04%
    Fir needle 25.55%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    10.0

    pKa est.
    8.08 (weak base)

    Molecular weight
    440.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    480°C

    Flash point

    • 164.85 ˚C est.

  • Synonyms

    • (23E)-CYCLOSADOL
    • CHEMBL225816
    • SCHEMBL13420421
    • DTXSID901318506
    • (23E)-24-Methyl-9beta-9,19-cyclolanost-23-en-3beta-ol
    • 25850-61-7
    • 25850-61-7

  • Applications

    (23E)-Cyclosadol is used as a fragrance ingredient in perfumery and cosmetics, potentially functioning as an odorant and fixative in fragrance formulations; it may also be evaluated for use in household cleaners as a scent additive. In the industrial sector, the compound can serve as an intermediate or processing aid in polymer and plastics formulations, and may be used as a solvent or carrier in certain formulation systems.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 3.38
    methanol 1.03
    isopropanol 3.56
    water 0.01
    ethyl acetate 8.26
    n-propanol 4.73
    acetone 5.63
    n-butanol 6.67
    acetonitrile 1.32
    DMF 5.86
    toluene 11.31
    isobutanol 4.26
    1,4-dioxane 12.18
    methyl acetate 4.03
    THF 17.13
    2-butanone 7.28
    n-pentanol 4.64
    sec-butanol 3.38
    n-hexane 0.93
    ethylene glycol 0.27
    NMP 9.78
    cyclohexane 1.04
    DMSO 2.42
    n-butyl acetate 10.36
    n-octanol 4.61
    chloroform 13.52
    n-propyl acetate 6.12
    acetic acid 2.88
    dichloromethane 7.14
    cyclohexanone 13.04
    propylene glycol 0.63
    isopropyl acetate 11.86
    DMAc 12.87
    2-ethoxyethanol 6.61
    isopentanol 7.24
    n-heptane 1.1
    ethyl formate 2.05
    1,2-dichloroethane 5.16
    n-hexanol 7.26
    2-methoxyethanol 6.24
    isobutyl acetate 7.96
    tetrachloromethane 4.02
    n-pentyl acetate 13.16
    transcutol 32.17
    n-heptanol 7.32
    ethylbenzene 5.49
    MIBK 11.8
    2-propoxyethanol 17.98
    tert-butanol 4.05
    MTBE 8.18
    2-butoxyethanol 17.73
    propionic acid 2.87
    o-xylene 7.21
    formic acid 0.67
    diethyl ether 8.76
    m-xylene 9.57
    p-xylene 6.11
    chlorobenzene 7.53
    dimethyl carbonate 4.16
    n-octane 0.39
    formamide 1.04
    cyclopentanone 11.47
    2-pentanone 9.96
    anisole 10.85
    cyclopentyl methyl ether 11.48
    gamma-butyrolactone 9.13
    1-methoxy-2-propanol 9.41
    pyridine 10.61
    3-pentanone 8.71
    furfural 8.22
    n-dodecane 0.22
    diethylene glycol 5.57
    diisopropyl ether 5.78
    tert-amyl alcohol 3.95
    acetylacetone 12.5
    n-hexadecane 0.27
    acetophenone 9.58
    methyl propionate 7.44
    isopentyl acetate 15.51
    trichloroethylene 11.89
    n-nonanol 6.07
    cyclohexanol 4.97
    benzyl alcohol 6.14
    2-ethylhexanol 6.42
    isooctanol 7.32
    dipropyl ether 10.09
    1,2-dichlorobenzene 7.91
    ethyl lactate 3.75
    propylene carbonate 6.0
    n-methylformamide 1.86
    2-pentanol 5.19
    n-pentane 1.12
    1-propoxy-2-propanol 15.95
    1-methoxy-2-propyl acetate 22.58
    2-(2-methoxypropoxy) propanol 15.66
    mesitylene 6.34
    ε-caprolactone 12.91
    p-cymene 5.81
    epichlorohydrin 10.75
    1,1,1-trichloroethane 8.7
    2-aminoethanol 1.17
    morpholine-4-carbaldehyde 15.22
    sulfolane 9.22
    2,2,4-trimethylpentane 0.93
    2-methyltetrahydrofuran 9.52
    n-hexyl acetate 13.61
    isooctane 1.03
    2-(2-butoxyethoxy)ethanol 19.46
    sec-butyl acetate 7.53
    tert-butyl acetate 16.22
    decalin 1.14
    glycerin 1.32
    diglyme 32.04
    acrylic acid 2.09
    isopropyl myristate 6.16
    n-butyric acid 7.41
    acetyl acetate 7.42
    di(2-ethylhexyl) phthalate 7.14
    ethyl propionate 7.52
    nitromethane 3.73
    1,2-diethoxyethane 13.1
    benzonitrile 4.61
    trioctyl phosphate 4.86
    1-bromopropane 5.08
    gamma-valerolactone 21.85
    n-decanol 3.7
    triethyl phosphate 6.89
    4-methyl-2-pentanol 5.92
    propionitrile 3.09
    vinylene carbonate 6.18
    1,1,2-trichlorotrifluoroethane 7.85
    DMS 9.28
    cumene 4.65
    2-octanol 4.2
    2-hexanone 7.38
    octyl acetate 6.56
    limonene 6.13
    1,2-dimethoxyethane 11.62
    ethyl orthosilicate 8.46
    tributyl phosphate 4.64
    diacetone alcohol 11.7
    N,N-dimethylaniline 9.65
    acrylonitrile 2.68
    aniline 8.16
    1,3-propanediol 3.36
    bromobenzene 8.75
    dibromomethane 5.87
    1,1,2,2-tetrachloroethane 9.97
    2-methyl-cyclohexyl acetate 11.23
    tetrabutyl urea 6.98
    diisobutyl methanol 5.97
    2-phenylethanol 11.22
    styrene 5.3
    dioctyl adipate 8.3
    dimethyl sulfate 5.78
    ethyl butyrate 9.52
    methyl lactate 3.94
    butyl lactate 9.85
    diethyl carbonate 6.01
    propanediol butyl ether 8.59
    triethyl orthoformate 11.9
    p-tert-butyltoluene 6.33
    methyl 4-tert-butylbenzoate 19.9
    morpholine 12.5
    tert-butylamine 3.36
    n-dodecanol 2.27
    dimethoxymethane 10.35
    ethylene carbonate 5.57
    cyrene 10.4
    2-ethoxyethyl acetate 19.6
    2-ethylhexyl acetate 12.9
    1,2,4-trichlorobenzene 11.06
    4-methylpyridine 11.82
    dibutyl ether 5.65
    2,6-dimethyl-4-heptanol 5.97
    DEF 9.42
    dimethyl isosorbide 24.78
    tetrachloroethylene 7.69
    eugenol 16.81
    triacetin 15.17
    span 80 12.26
    1,4-butanediol 1.29
    1,1-dichloroethane 5.74
    2-methyl-1-pentanol 5.43
    methyl formate 1.25
    2-methyl-1-butanol 5.92
    n-decane 0.6
    butyronitrile 3.96
    3,7-dimethyl-1-octanol 5.79
    1-chlorooctane 2.66
    1-chlorotetradecane 0.85
    n-nonane 0.47
    undecane 0.34
    tert-butylcyclohexane 1.24
    cyclooctane 0.68
    cyclopentanol 3.39
    tetrahydropyran 11.19
    tert-amyl methyl ether 6.95
    2,5,8-trioxanonane 21.25
    1-hexene 2.6
    2-isopropoxyethanol 7.2
    2,2,2-trifluoroethanol 1.7
    methyl butyrate 6.61

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction