2,3-Lutidine

Overview IFRA Request a quote

  • Identifiers

    CAS number
    583-61-9

    Molecular formula
    C7H9N

    SMILES
    CC1=C(N=CC=C1)C

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Roasted 63.84%
    Nutty 61.97%
    Green 55.34%
    Earthy 53.85%
    Musty 47.82%
    Tobacco 46.15%
    Burnt 45.39%
    Fishy 45.38%
    Animal 43.99%
    Coffee 41.74%

     

    Flavor
    Nutty 70.79%
    Roasted 47.45%
    Earthy 45.86%
    Musty 44.12%
    Cocoa 41.61%
    Coffee 37.31%
    Potato 35.39%
    Leather 35.35%
    Woody 35.3%
    Hazelnut 34.84%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.6

    pKa est.
    5.81 (weak acid)

    Molecular weight
    107.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point est.
    162°C

    Flash point

    • 39.53 ˚C est.

  • Synonyms

    • 2,3-Lutidine
    • 2,3-DIMETHYLPYRIDINE
    • 583-61-9
    • Pyridine, 2,3-dimethyl-
    • DIMETHYLPYRIDINE
    • 2,3-dimethyl-pyridine
    • 5Q0F649H6G
    • NSC 2157
    • NSC-2157
    • EINECS 209-514-1
    • AI3-24280
    • DTXSID6060395
    • Pyridine, dimethyl-
    • MFCD00009605
    • UNII-5Q0F649H6G
    • 2,3dimethylpyridine
    • EINECS 248-287-3
    • 2-3-Lutidine
    • Pyridine,3-dimethyl-
    • 2,3-d1methylpyridine
    • Pyridine, 2,3dimethyl
    • 2,3-Lutidine (8CI)
    • 2,3-Lutidine, 99%
    • SCHEMBL65397
    • CHEMBL3303914
    • DTXCID1042360
    • NSC2157
    • BCP26360
    • AKOS009028879
    • CS-W011290
    • BP-21057
    • CS-17343
    • DB-024146
    • L0063
    • NS00022423
    • EN300-19111
    • P19755
    • A831849
    • Q27262718
    • 2,3-Dimethylpyridine;Dimethylpyridine;Pyridine, 2,3-dimethyl-
    • 209-514-1

  • Applications

    2,3-Lutidine (CAS 583-61-9) is commonly used as an organic solvent and reaction medium in chemical synthesis; it also serves as a convenient base in acylation and condensation reactions, and acts as a chemical intermediate for dyes, pharmaceuticals, and agrochemicals. In catalytic and processing contexts, it may function as a ligand or co-catalyst in organometallic systems, helping stabilize reactive species. These applications illustrate its role as a versatile pyridine derivative across industrial manufacturing and formulation tasks.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 697.22
    methanol 1054.19
    isopropanol 405.42
    water 14.42
    ethyl acetate 526.92
    n-propanol 556.47
    acetone 315.06
    n-butanol 510.08
    acetonitrile 431.6
    DMF 471.96
    toluene 342.8
    isobutanol 368.04
    1,4-dioxane 757.48
    methyl acetate 431.05
    THF 725.86
    2-butanone 419.93
    n-pentanol 372.33
    sec-butanol 395.98
    n-hexane 117.67
    ethylene glycol 110.82
    NMP 450.41
    cyclohexane 112.27
    DMSO 335.24
    n-butyl acetate 390.67
    n-octanol 110.46
    chloroform 1993.64
    n-propyl acetate 230.9
    acetic acid 407.8
    dichloromethane 1710.03
    cyclohexanone 500.0
    propylene glycol 113.23
    isopropyl acetate 236.1
    DMAc 469.61
    2-ethoxyethanol 372.56
    isopentanol 353.11
    n-heptane 83.75
    ethyl formate 386.83
    1,2-dichloroethane 804.51
    n-hexanol 366.27
    2-methoxyethanol 569.78
    isobutyl acetate 131.22
    tetrachloromethane 482.68
    n-pentyl acetate 207.42
    transcutol 824.55
    n-heptanol 161.45
    ethylbenzene 115.95
    MIBK 167.76
    2-propoxyethanol 459.99
    tert-butanol 360.18
    MTBE 363.0
    2-butoxyethanol 252.5
    propionic acid 429.51
    o-xylene 185.6
    formic acid 302.05
    diethyl ether 657.63
    m-xylene 173.96
    p-xylene 148.55
    chlorobenzene 406.68
    dimethyl carbonate 119.6
    n-octane 28.89
    formamide 404.88
    cyclopentanone 503.9
    2-pentanone 333.95
    anisole 239.81
    cyclopentyl methyl ether 401.55
    gamma-butyrolactone 583.62
    1-methoxy-2-propanol 328.96
    pyridine 709.59
    3-pentanone 315.01
    furfural 565.0
    n-dodecane 15.31
    diethylene glycol 252.89
    diisopropyl ether 129.11
    tert-amyl alcohol 356.23
    acetylacetone 238.27
    n-hexadecane 16.85
    acetophenone 177.44
    methyl propionate 371.06
    isopentyl acetate 255.89
    trichloroethylene 1178.97
    n-nonanol 105.78
    cyclohexanol 293.22
    benzyl alcohol 203.55
    2-ethylhexanol 198.37
    isooctanol 122.46
    dipropyl ether 289.53
    1,2-dichlorobenzene 314.22
    ethyl lactate 87.3
    propylene carbonate 294.58
    n-methylformamide 460.85
    2-pentanol 294.4
    n-pentane 119.11
    1-propoxy-2-propanol 293.87
    1-methoxy-2-propyl acetate 231.48
    2-(2-methoxypropoxy) propanol 161.14
    mesitylene 96.17
    ε-caprolactone 432.8
    p-cymene 83.38
    epichlorohydrin 681.52
    1,1,1-trichloroethane 765.45
    2-aminoethanol 270.4
    morpholine-4-carbaldehyde 481.28
    sulfolane 426.32
    2,2,4-trimethylpentane 47.94
    2-methyltetrahydrofuran 621.8
    n-hexyl acetate 199.84
    isooctane 31.84
    2-(2-butoxyethoxy)ethanol 245.64
    sec-butyl acetate 144.23
    tert-butyl acetate 189.04
    decalin 45.99
    glycerin 143.52
    diglyme 446.21
    acrylic acid 303.71
    isopropyl myristate 77.16
    n-butyric acid 564.02
    acetyl acetate 237.54
    di(2-ethylhexyl) phthalate 74.06
    ethyl propionate 215.59
    nitromethane 581.02
    1,2-diethoxyethane 473.64
    benzonitrile 292.04
    trioctyl phosphate 52.15
    1-bromopropane 606.71
    gamma-valerolactone 606.99
    n-decanol 75.97
    triethyl phosphate 95.01
    4-methyl-2-pentanol 137.88
    propionitrile 469.45
    vinylene carbonate 333.7
    1,1,2-trichlorotrifluoroethane 397.35
    DMS 143.98
    cumene 82.43
    2-octanol 96.24
    2-hexanone 225.11
    octyl acetate 99.39
    limonene 127.77
    1,2-dimethoxyethane 467.95
    ethyl orthosilicate 105.76
    tributyl phosphate 71.25
    diacetone alcohol 173.77
    N,N-dimethylaniline 154.24
    acrylonitrile 459.36
    aniline 418.11
    1,3-propanediol 344.0
    bromobenzene 413.0
    dibromomethane 1153.65
    1,1,2,2-tetrachloroethane 894.38
    2-methyl-cyclohexyl acetate 139.22
    tetrabutyl urea 83.49
    diisobutyl methanol 95.28
    2-phenylethanol 221.81
    styrene 164.52
    dioctyl adipate 92.21
    dimethyl sulfate 147.59
    ethyl butyrate 249.49
    methyl lactate 118.4
    butyl lactate 116.27
    diethyl carbonate 148.42
    propanediol butyl ether 125.9
    triethyl orthoformate 172.22
    p-tert-butyltoluene 79.38
    methyl 4-tert-butylbenzoate 137.44
    morpholine 808.63
    tert-butylamine 281.55
    n-dodecanol 57.98
    dimethoxymethane 341.7
    ethylene carbonate 290.84
    cyrene 130.15
    2-ethoxyethyl acetate 269.69
    2-ethylhexyl acetate 224.66
    1,2,4-trichlorobenzene 341.43
    4-methylpyridine 632.04
    dibutyl ether 186.18
    2,6-dimethyl-4-heptanol 95.28
    DEF 419.04
    dimethyl isosorbide 252.19
    tetrachloroethylene 737.17
    eugenol 141.02
    triacetin 137.67
    span 80 132.94
    1,4-butanediol 139.46
    1,1-dichloroethane 863.41
    2-methyl-1-pentanol 307.81
    methyl formate 259.14
    2-methyl-1-butanol 377.23
    n-decane 27.95
    butyronitrile 469.36
    3,7-dimethyl-1-octanol 115.68
    1-chlorooctane 92.91
    1-chlorotetradecane 35.54
    n-nonane 28.7
    undecane 19.46
    tert-butylcyclohexane 48.83
    cyclooctane 39.96
    cyclopentanol 312.76
    tetrahydropyran 663.35
    tert-amyl methyl ether 290.27
    2,5,8-trioxanonane 278.64
    1-hexene 284.09
    2-isopropoxyethanol 223.6
    2,2,2-trifluoroethanol 172.66
    methyl butyrate 272.56

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction