(2,3-Dihydroxypropyl)trimethylammonium chloride

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  • Identifiers

    CAS number
    34004-36-9

    Molecular formula
    C6H16ClNO2

    SMILES
    C[N+](C)(C)CC(CO)O.[Cl-]

    Safety labels

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Alcoholic 33.72%
    Odorless 33.39%
    Fruity 32.01%
    Fermented 29.49%
    Oily 27.78%
    Fishy 26.27%
    Mint 24.83%
    Ethereal 22.42%
    Solvent 22.3%
    Cheesy 21.42%

     

    Flavor
    Odorless 32.54%
    Mild 31.82%
    Sulfurous 25.28%
    Bland 24.59%
    Sweet 21.98%
    Yeasty 21.78%
    Sweet-like 21.52%
    Catty 20.81%
    Very slight 20.56%
    Black currant 20.52%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.28 (neutral)

    Molecular weight
    169.65 g/mol

    Flash point

    • -86.59 ˚C est.

  • Synonyms

    • 34004-36-9
    • (2,3-Dihydroxypropyl)trimethylammonium chloride
    • Dihydroxypropyltrimonium chloride
    • V5RP514IX5
    • PD QUAT
    • Ammonium, (2,3-dihydroxypropyl)trimethyl-, chloride
    • DTXSID4052766
    • 1-Propanaminium, 2,3-dihydroxy-N,N,N-trimethyl-, chloride (1:1)
    • RefChem:587788
    • 2,3-DHP-TACl
    • DTXCID9031353
    • 251-783-2
    • 2,3-dihydroxy-n,n,n-trimethylpropan-1-aminium chloride
    • (2,3-Dihydroxypropyl)trimethylammoniumchloride
    • MFCD01668726
    • 1-Propanaminium, 2,3-dihydroxy-N,N,N-trimethyl-, chloride
    • 2,3-dihydroxypropyl(trimethyl)azanium;chloride
    • EINECS 251-783-2
    • UNII-V5RP514IX5
    • Levocarnitine Impurity 45
    • SCHEMBL35525
    • Glyceryltrimethylammoniumchlorid
    • JBA00436
    • AKOS006278182
    • DS-19355
    • SY308181
    • 2,3-dihydroxypropyltrimethylammonium chloride
    • CS-0163235
    • NS00019564
    • 2,3-dihy-droxypropyl trimethylammonium chloride
    • 2,3-dihydroxypropyl(trimethyl)ammonium;chloride
    • F16434
    • EN300-1273337
    • F053977
    • (2,3-DIHYDROXYPROPYL)TRIMETHYLAZANIUM CHLORIDE
    • 2,3-dihydroxy-n,n,n-trimethylpropan-1-aminiumchloride
    • Q27291567
    • (2,3-Dihydroxypropyl)trimethylammonium chloride (dhptac)
    • 34004-36-9

  • Applications

    (2,3-Dihydroxypropyl)trimethylammonium chloride is a versatile quaternary ammonium salt that functions as a cationic surfactant and conditioning agent in cosmetics and personal care, including hair conditioning and anti-static formulations. It is also used as a cleaning and fabric-softening additive in household products, and as a hydrophilic building block or intermediate for the synthesis of other quaternary ammonium surfactants and cationic polymers in industrial manufacturing; additionally it can serve as a functional additive in coatings and inks to improve wettability and adhesion and may be used as a reactive intermediate in polymer and plastics processing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 40.65
    methanol 170.69
    isopropanol 7.38
    water 816.72
    ethyl acetate 1.75
    n-propanol 20.85
    acetone 0.96
    n-butanol 7.2
    acetonitrile 2.06
    DMF 9.73
    toluene 0.28
    isobutanol 6.12
    1,4-dioxane 4.87
    methyl acetate 3.1
    THF 4.17
    2-butanone 1.51
    n-pentanol 1.79
    sec-butanol 7.32
    n-hexane 0.15
    ethylene glycol 285.88
    NMP 40.81
    cyclohexane 0.36
    DMSO 9.98
    n-butyl acetate 2.19
    n-octanol 3.03
    chloroform 7.12
    n-propyl acetate 0.95
    acetic acid 260.09
    dichloromethane 4.3
    cyclohexanone 3.56
    propylene glycol 136.87
    isopropyl acetate 0.63
    DMAc 13.5
    2-ethoxyethanol 16.06
    isopentanol 1.68
    n-heptane 0.56
    ethyl formate 5.46
    1,2-dichloroethane 1.47
    n-hexanol 6.45
    2-methoxyethanol 63.81
    isobutyl acetate 0.6
    tetrachloromethane 3.39
    n-pentyl acetate 1.51
    transcutol 19.45
    n-heptanol 5.1
    ethylbenzene 0.23
    MIBK 0.33
    2-propoxyethanol 25.44
    tert-butanol 3.88
    MTBE 0.7
    2-butoxyethanol 14.58
    propionic acid 60.92
    o-xylene 0.56
    formic acid 814.67
    diethyl ether 0.73
    m-xylene 0.36
    p-xylene 0.3
    chlorobenzene 0.77
    dimethyl carbonate 1.99
    n-octane 0.19
    formamide 173.6
    cyclopentanone 4.43
    2-pentanone 0.58
    anisole 0.75
    cyclopentyl methyl ether 1.63
    gamma-butyrolactone 14.52
    1-methoxy-2-propanol 16.82
    pyridine 3.32
    3-pentanone 0.89
    furfural 25.24
    n-dodecane 0.15
    diethylene glycol 70.5
    diisopropyl ether 0.18
    tert-amyl alcohol 5.43
    acetylacetone 0.93
    n-hexadecane 0.15
    acetophenone 1.5
    methyl propionate 3.07
    isopentyl acetate 1.68
    trichloroethylene 5.23
    n-nonanol 2.7
    cyclohexanol 5.56
    benzyl alcohol 2.83
    2-ethylhexanol 2.86
    isooctanol 3.11
    dipropyl ether 1.29
    1,2-dichlorobenzene 1.51
    ethyl lactate 6.24
    propylene carbonate 8.84
    n-methylformamide 31.97
    2-pentanol 1.89
    n-pentane 0.22
    1-propoxy-2-propanol 13.37
    1-methoxy-2-propyl acetate 3.89
    2-(2-methoxypropoxy) propanol 11.81
    mesitylene 0.32
    ε-caprolactone 8.16
    p-cymene 0.99
    epichlorohydrin 4.9
    1,1,1-trichloroethane 1.35
    2-aminoethanol 199.48
    morpholine-4-carbaldehyde 30.39
    sulfolane 27.21
    2,2,4-trimethylpentane 0.23
    2-methyltetrahydrofuran 2.61
    n-hexyl acetate 2.31
    isooctane 0.09
    2-(2-butoxyethoxy)ethanol 13.41
    sec-butyl acetate 0.53
    tert-butyl acetate 0.73
    decalin 0.19
    glycerin 312.63
    diglyme 15.13
    acrylic acid 99.28
    isopropyl myristate 0.77
    n-butyric acid 22.58
    acetyl acetate 1.87
    di(2-ethylhexyl) phthalate 3.73
    ethyl propionate 1.09
    nitromethane 37.77
    1,2-diethoxyethane 0.98
    benzonitrile 1.59
    trioctyl phosphate 2.57
    1-bromopropane 0.72
    gamma-valerolactone 15.66
    n-decanol 1.87
    triethyl phosphate 2.7
    4-methyl-2-pentanol 0.73
    propionitrile 2.11
    vinylene carbonate 10.98
    1,1,2-trichlorotrifluoroethane 64.52
    DMS 3.15
    cumene 0.33
    2-octanol 1.96
    2-hexanone 0.46
    octyl acetate 1.57
    limonene 1.27
    1,2-dimethoxyethane 3.84
    ethyl orthosilicate 2.45
    tributyl phosphate 2.5
    diacetone alcohol 3.2
    N,N-dimethylaniline 0.96
    acrylonitrile 4.29
    aniline 2.41
    1,3-propanediol 86.19
    bromobenzene 0.48
    dibromomethane 2.38
    1,1,2,2-tetrachloroethane 5.36
    2-methyl-cyclohexyl acetate 3.03
    tetrabutyl urea 2.88
    diisobutyl methanol 1.33
    2-phenylethanol 4.78
    styrene 0.22
    dioctyl adipate 2.04
    dimethyl sulfate 6.09
    ethyl butyrate 1.88
    methyl lactate 14.38
    butyl lactate 6.42
    diethyl carbonate 1.69
    propanediol butyl ether 19.04
    triethyl orthoformate 2.35
    p-tert-butyltoluene 1.09
    methyl 4-tert-butylbenzoate 5.82
    morpholine 10.18
    tert-butylamine 1.75
    n-dodecanol 1.34
    dimethoxymethane 3.19
    ethylene carbonate 6.51
    cyrene 19.2
    2-ethoxyethyl acetate 2.52
    2-ethylhexyl acetate 1.53
    1,2,4-trichlorobenzene 2.59
    4-methylpyridine 1.3
    dibutyl ether 0.51
    2,6-dimethyl-4-heptanol 1.33
    DEF 2.64
    dimethyl isosorbide 15.33
    tetrachloroethylene 8.98
    eugenol 9.21
    triacetin 5.42
    span 80 16.41
    1,4-butanediol 19.93
    1,1-dichloroethane 0.94
    2-methyl-1-pentanol 1.02
    methyl formate 17.3
    2-methyl-1-butanol 3.57
    n-decane 0.22
    butyronitrile 1.1
    3,7-dimethyl-1-octanol 1.86
    1-chlorooctane 0.68
    1-chlorotetradecane 0.32
    n-nonane 0.21
    undecane 0.17
    tert-butylcyclohexane 0.19
    cyclooctane 0.18
    cyclopentanol 9.35
    tetrahydropyran 1.96
    tert-amyl methyl ether 1.09
    2,5,8-trioxanonane 13.5
    1-hexene 0.24
    2-isopropoxyethanol 5.11
    2,2,2-trifluoroethanol 145.38
    methyl butyrate 1.45

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction