2,3-Dihydroxypropyl 5-hydroxydodecanoate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    26446-32-2

    Molecular formula
    C15H30O5

    SMILES
    CCCCCCCC(CCCC(=O)OCC(CO)O)O

  • Odor profile

    Fragrance
    Fruity 59.98%
    Oily 56.16%
    Fatty 46.19%
    Peach 45.89%
    Lactonic 43.46%
    Fresh 41.68%
    Buttery 41.13%
    Sweet 38.82%
    Tropical 32.86%
    Coconut 31.73%

     

    Flavor
    Odorless 40.3%
    Fruity 38.81%
    Sweet 37.51%
    Waxy 37.21%
    Fatty 33.81%
    Oily 32.84%
    Mild 32.45%
    Bland 24.68%
    Sweet-like 24.62%
    Creamy 24.13%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.4

    pKa est.
    6.34 (neutral)

    Molecular weight
    290.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point

    • 120.00 °C. @ 1.00 mm Hg

    Flash point

    • 194.0 ˚C est.

    Solubility expt.

    • insoluble in water; soluble in hot organic solvents, oils
    • soluble in hot alcohol (in ethanol)

  • Synonyms

    • 2,3-Dihydroxypropyl 5-hydroxydodecanoate
    • 26446-32-2
    • Glyceryl 5-hydroxydodecanoate
    • Glycerol 5-hydroxydodecanoate
    • 93762-24-4
    • Glycerol 1-(5-hydroxydodecanoate)
    • Glyceryl 1-(5-hydroxydodecanoate)
    • Glyceryl mono(5-hydroxydodecanoate)
    • Glycerol, mono(5-hydroxydodecanoate)
    • UNII-8WO593UA3G
    • 2,3-Dihydroxypropyl 5-hydroxylaurate
    • 5-Hydroxydodecanoic acid, monoester with glycerol
    • FEMA No. 3686
    • Dodecanoic acid, 5-hydroxy-, 2,3-dihydroxypropyl ester
    • EINECS 247-700-4
    • 1,2,3-Propanetriol mono(5-hydroxydodecanoate)
    • Dodecanoic acid, 5-hydroxy-, monoester with glycerol
    • Glyceryl-5-hydroxydodecanoate
    • 4504N9GBRR
    • 8WO593UA3G
    • Dodecanoic acid, 5-hydroxy-, monoester with 1,2,3-propanetriol
    • UNII-4504N9GBRR
    • EINECS 297-738-0
    • SCHEMBL3504147
    • DTXSID20888721
    • CHEBI:174087
    • KCEQGTJBAICOKH-UHFFFAOYSA-N
    • FEMA NO. 3686, 1-MONO-
    • NS00050915
    • Q27258779
    • (+/-)-2,3-DIHYDROXYPROPYL 5-HYDROXYDODECANOATE
    • 2,3-DIHYDROXYPROPYL 5-HYDROXYDODECANOATE, (+/-)-

  • Applications

    2,3-Dihydroxypropyl 5-hydroxydodecanoate, CAS 26446-32-2, is used in cosmetics and personal care as a fatty acid ester that acts as an emollient and humectant for skin and hair, and can function as a mild surfactant or emulsifier in formulations. In plastics and polymers, it is employed as a plasticizer or processing aid to improve flexibility and workability. As a chemical intermediate, it can be used to synthesize other fatty ester derivatives for coatings, paints, or adhesives. In industrial and cleaning formulations, it may serve as a surfactant component and lubricating additive to enhance mixing and cleaning performance. Applications are subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 175.53
    methanol 659.86
    isopropanol 71.44
    water 1.61
    ethyl acetate 86.05
    n-propanol 90.42
    acetone 146.15
    n-butanol 73.21
    acetonitrile 30.4
    DMF 523.32
    toluene 9.55
    isobutanol 58.6
    1,4-dioxane 121.52
    methyl acetate 51.41
    THF 320.32
    2-butanone 62.16
    n-pentanol 60.27
    sec-butanol 54.19
    n-hexane 1.2
    ethylene glycol 72.25
    NMP 406.43
    cyclohexane 4.04
    DMSO 1684.98
    n-butyl acetate 57.54
    n-octanol 31.96
    chloroform 42.09
    n-propyl acetate 78.54
    acetic acid 314.6
    dichloromethane 54.14
    cyclohexanone 200.75
    propylene glycol 112.02
    isopropyl acetate 86.87
    DMAc 452.18
    2-ethoxyethanol 288.43
    isopentanol 79.76
    n-heptane 1.55
    ethyl formate 61.08
    1,2-dichloroethane 56.33
    n-hexanol 40.71
    2-methoxyethanol 524.39
    isobutyl acetate 49.52
    tetrachloromethane 8.0
    n-pentyl acetate 59.32
    transcutol 962.37
    n-heptanol 33.82
    ethylbenzene 9.56
    MIBK 84.48
    2-propoxyethanol 178.88
    tert-butanol 133.52
    MTBE 54.35
    2-butoxyethanol 130.5
    propionic acid 123.13
    o-xylene 16.62
    formic acid 277.47
    diethyl ether 29.2
    m-xylene 15.66
    p-xylene 12.94
    chlorobenzene 15.93
    dimethyl carbonate 47.44
    n-octane 1.13
    formamide 392.51
    cyclopentanone 247.05
    2-pentanone 94.83
    anisole 37.98
    cyclopentyl methyl ether 104.76
    gamma-butyrolactone 291.68
    1-methoxy-2-propanol 367.58
    pyridine 55.52
    3-pentanone 48.26
    furfural 255.46
    n-dodecane 1.04
    diethylene glycol 206.52
    diisopropyl ether 14.75
    tert-amyl alcohol 97.62
    acetylacetone 218.51
    n-hexadecane 1.19
    acetophenone 68.74
    methyl propionate 82.4
    isopentyl acetate 66.38
    trichloroethylene 105.57
    n-nonanol 30.23
    cyclohexanol 90.5
    benzyl alcohol 56.78
    2-ethylhexanol 26.69
    isooctanol 31.37
    dipropyl ether 24.27
    1,2-dichlorobenzene 24.91
    ethyl lactate 74.39
    propylene carbonate 148.48
    n-methylformamide 211.0
    2-pentanol 43.75
    n-pentane 1.0
    1-propoxy-2-propanol 123.07
    1-methoxy-2-propyl acetate 120.62
    2-(2-methoxypropoxy) propanol 136.54
    mesitylene 13.57
    ε-caprolactone 198.08
    p-cymene 10.4
    epichlorohydrin 215.78
    1,1,1-trichloroethane 31.27
    2-aminoethanol 168.25
    morpholine-4-carbaldehyde 367.25
    sulfolane 660.24
    2,2,4-trimethylpentane 2.13
    2-methyltetrahydrofuran 114.64
    n-hexyl acetate 72.14
    isooctane 1.52
    2-(2-butoxyethoxy)ethanol 217.58
    sec-butyl acetate 52.53
    tert-butyl acetate 124.62
    decalin 3.34
    glycerin 248.8
    diglyme 428.75
    acrylic acid 109.26
    isopropyl myristate 23.84
    n-butyric acid 192.51
    acetyl acetate 81.39
    di(2-ethylhexyl) phthalate 36.27
    ethyl propionate 58.76
    nitromethane 443.42
    1,2-diethoxyethane 100.59
    benzonitrile 39.86
    trioctyl phosphate 26.57
    1-bromopropane 14.41
    gamma-valerolactone 443.63
    n-decanol 20.13
    triethyl phosphate 37.05
    4-methyl-2-pentanol 36.56
    propionitrile 22.51
    vinylene carbonate 111.32
    1,1,2-trichlorotrifluoroethane 305.88
    DMS 67.1
    cumene 9.78
    2-octanol 20.76
    2-hexanone 63.05
    octyl acetate 32.42
    limonene 17.45
    1,2-dimethoxyethane 299.27
    ethyl orthosilicate 35.73
    tributyl phosphate 34.44
    diacetone alcohol 229.09
    N,N-dimethylaniline 37.2
    acrylonitrile 39.27
    aniline 29.34
    1,3-propanediol 248.05
    bromobenzene 14.29
    dibromomethane 26.66
    1,1,2,2-tetrachloroethane 102.06
    2-methyl-cyclohexyl acetate 56.13
    tetrabutyl urea 49.64
    diisobutyl methanol 19.97
    2-phenylethanol 43.33
    styrene 10.25
    dioctyl adipate 57.95
    dimethyl sulfate 150.7
    ethyl butyrate 52.55
    methyl lactate 117.87
    butyl lactate 91.78
    diethyl carbonate 34.22
    propanediol butyl ether 162.87
    triethyl orthoformate 48.2
    p-tert-butyltoluene 11.42
    methyl 4-tert-butylbenzoate 93.42
    morpholine 225.82
    tert-butylamine 41.57
    n-dodecanol 13.98
    dimethoxymethane 224.84
    ethylene carbonate 98.89
    cyrene 144.68
    2-ethoxyethyl acetate 106.96
    2-ethylhexyl acetate 42.17
    1,2,4-trichlorobenzene 36.32
    4-methylpyridine 50.41
    dibutyl ether 27.97
    2,6-dimethyl-4-heptanol 19.97
    DEF 176.61
    dimethyl isosorbide 213.33
    tetrachloroethylene 68.96
    eugenol 93.71
    triacetin 144.71
    span 80 116.91
    1,4-butanediol 83.58
    1,1-dichloroethane 23.63
    2-methyl-1-pentanol 58.28
    methyl formate 120.21
    2-methyl-1-butanol 65.23
    n-decane 1.97
    butyronitrile 29.07
    3,7-dimethyl-1-octanol 35.12
    1-chlorooctane 10.8
    1-chlorotetradecane 3.91
    n-nonane 1.72
    undecane 1.35
    tert-butylcyclohexane 2.69
    cyclooctane 1.89
    cyclopentanol 104.63
    tetrahydropyran 86.31
    tert-amyl methyl ether 49.13
    2,5,8-trioxanonane 273.38
    1-hexene 5.28
    2-isopropoxyethanol 159.83
    2,2,2-trifluoroethanol 118.06
    methyl butyrate 100.43

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction