2,3-Diethyl-5,6-dimethylpyrazine

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  • Identifiers

    CAS number
    34514-53-9

    Molecular formula
    C10H16N2

    SMILES
    CCC1=NC(=C(N=C1CC)C)C

    Safety labels

  • Odor profile

    Fragrance
    Nutty 76.85%
    Roasted 69.96%
    Earthy 65.14%
    Cocoa 59.58%
    Burnt 58.35%
    Musty 57.24%
    Hazelnut 55.63%
    Coffee 49.81%
    Potato 49.81%
    Chocolate 48.84%

     

    Flavor
    Nutty 67.22%
    Earthy 59.64%
    Meaty 50.66%
    Potato 50.21%
    Roasted 50.02%
    Musty 48.17%
    Hazelnut 47.1%
    Vegetable 44.71%
    Green 40.45%
    Roast 40.37%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.2

    pKa est.
    5.5 (weak acid)

    Molecular weight
    164.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point est.
    224°C

    Flash point

    • 78.2 ˚C est.

  • Synonyms

    • 2,3-Diethyl-5,6-dimethylpyrazine
    • 2,3-diethyl-5,6-dimethyl-pyrazine
    • 34514-53-9
    • DTXSID20188071
    • RefChem:81629
    • 106060-96-2
    • DTXCID50110562
    • YAGSHZPMYHTMPZ-UHFFFAOYSA-N
    • SCHEMBL8020079
    • SCHEMBL30689650
    • CHEBI:193707
    • AKOS006373896
    • 34514-53-9

  • Applications

    2,3-Diethyl-5,6-dimethylpyrazine (CAS 34514-53-9) is primarily used as an odorant and flavor contributor in fragrance and flavor formulations; it often provides roasty, nutty, or savory notes that help shape aroma profiles in perfumery and processed foods. It may also be employed in cosmetics and personal care as a fragrance ingredient, and in household products as a fragrance component for cleaners and air fresheners. In industrial manufacturing, it can serve as an intermediate or building block in organic synthesis for the development of other pyrazine derivatives or related materials. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 447.14
    methanol 491.28
    isopropanol 372.02
    water 2.28
    ethyl acetate 919.0
    n-propanol 492.41
    acetone 894.39
    n-butanol 463.35
    acetonitrile 636.91
    DMF 1192.54
    toluene 885.98
    isobutanol 404.43
    1,4-dioxane 1214.82
    methyl acetate 851.77
    THF 1628.97
    2-butanone 930.97
    n-pentanol 390.66
    sec-butanol 464.8
    n-hexane 384.43
    ethylene glycol 101.94
    NMP 1538.05
    cyclohexane 564.83
    DMSO 768.48
    n-butyl acetate 1064.24
    n-octanol 438.98
    chloroform 4392.02
    n-propyl acetate 709.63
    acetic acid 433.92
    dichloromethane 4050.12
    cyclohexanone 1681.17
    propylene glycol 134.29
    isopropyl acetate 590.43
    DMAc 1144.4
    2-ethoxyethanol 406.69
    isopentanol 384.67
    n-heptane 328.27
    ethyl formate 756.41
    1,2-dichloroethane 2130.77
    n-hexanol 536.82
    2-methoxyethanol 581.52
    isobutyl acetate 499.22
    tetrachloromethane 1317.39
    n-pentyl acetate 746.22
    transcutol 654.53
    n-heptanol 381.88
    ethylbenzene 671.62
    MIBK 461.64
    2-propoxyethanol 572.16
    tert-butanol 399.63
    MTBE 580.53
    2-butoxyethanol 446.39
    propionic acid 501.61
    o-xylene 691.03
    formic acid 135.02
    diethyl ether 794.26
    m-xylene 644.65
    p-xylene 1000.5
    chlorobenzene 1400.25
    dimethyl carbonate 457.63
    n-octane 196.2
    formamide 215.0
    cyclopentanone 1817.82
    2-pentanone 778.2
    anisole 728.41
    cyclopentyl methyl ether 988.39
    gamma-butyrolactone 1943.85
    1-methoxy-2-propanol 450.81
    pyridine 1482.67
    3-pentanone 848.12
    furfural 1667.64
    n-dodecane 141.05
    diethylene glycol 287.58
    diisopropyl ether 320.88
    tert-amyl alcohol 445.35
    acetylacetone 868.76
    n-hexadecane 164.84
    acetophenone 758.15
    methyl propionate 802.38
    isopentyl acetate 839.34
    trichloroethylene 3712.74
    n-nonanol 366.35
    cyclohexanol 618.2
    benzyl alcohol 510.12
    2-ethylhexanol 472.05
    isooctanol 312.73
    dipropyl ether 665.91
    1,2-dichlorobenzene 1428.63
    ethyl lactate 317.77
    propylene carbonate 1248.8
    n-methylformamide 584.1
    2-pentanol 359.9
    n-pentane 299.17
    1-propoxy-2-propanol 469.51
    1-methoxy-2-propyl acetate 649.62
    2-(2-methoxypropoxy) propanol 336.2
    mesitylene 485.33
    ε-caprolactone 1343.59
    p-cymene 534.78
    epichlorohydrin 1854.57
    1,1,1-trichloroethane 2384.42
    2-aminoethanol 181.64
    morpholine-4-carbaldehyde 1209.5
    sulfolane 1830.16
    2,2,4-trimethylpentane 162.91
    2-methyltetrahydrofuran 1266.33
    n-hexyl acetate 893.88
    isooctane 105.24
    2-(2-butoxyethoxy)ethanol 394.51
    sec-butyl acetate 486.97
    tert-butyl acetate 523.81
    decalin 296.64
    glycerin 164.18
    diglyme 868.83
    acrylic acid 458.22
    isopropyl myristate 403.04
    n-butyric acid 677.23
    acetyl acetate 698.31
    di(2-ethylhexyl) phthalate 326.7
    ethyl propionate 731.56
    nitromethane 831.63
    1,2-diethoxyethane 664.27
    benzonitrile 963.87
    trioctyl phosphate 288.53
    1-bromopropane 1362.22
    gamma-valerolactone 1703.95
    n-decanol 282.43
    triethyl phosphate 443.34
    4-methyl-2-pentanol 215.74
    propionitrile 680.44
    vinylene carbonate 1337.21
    1,1,2-trichlorotrifluoroethane 984.89
    DMS 734.58
    cumene 494.11
    2-octanol 365.54
    2-hexanone 712.83
    octyl acetate 493.04
    limonene 673.96
    1,2-dimethoxyethane 926.56
    ethyl orthosilicate 400.18
    tributyl phosphate 358.0
    diacetone alcohol 391.67
    N,N-dimethylaniline 636.05
    acrylonitrile 815.65
    aniline 673.66
    1,3-propanediol 289.83
    bromobenzene 1803.31
    dibromomethane 2846.3
    1,1,2,2-tetrachloroethane 3054.27
    2-methyl-cyclohexyl acetate 605.35
    tetrabutyl urea 442.64
    diisobutyl methanol 265.64
    2-phenylethanol 558.24
    styrene 756.16
    dioctyl adipate 507.57
    dimethyl sulfate 642.71
    ethyl butyrate 807.15
    methyl lactate 312.67
    butyl lactate 441.08
    diethyl carbonate 628.3
    propanediol butyl ether 319.03
    triethyl orthoformate 561.75
    p-tert-butyltoluene 479.15
    methyl 4-tert-butylbenzoate 599.52
    morpholine 1039.25
    tert-butylamine 341.86
    n-dodecanol 235.93
    dimethoxymethane 937.79
    ethylene carbonate 1097.96
    cyrene 422.47
    2-ethoxyethyl acetate 694.06
    2-ethylhexyl acetate 816.61
    1,2,4-trichlorobenzene 1472.85
    4-methylpyridine 1457.36
    dibutyl ether 683.05
    2,6-dimethyl-4-heptanol 265.64
    DEF 978.35
    dimethyl isosorbide 729.68
    tetrachloroethylene 2260.76
    eugenol 483.97
    triacetin 617.18
    span 80 384.63
    1,4-butanediol 166.4
    1,1-dichloroethane 2044.14
    2-methyl-1-pentanol 367.97
    methyl formate 628.73
    2-methyl-1-butanol 426.0
    n-decane 229.68
    butyronitrile 794.29
    3,7-dimethyl-1-octanol 372.57
    1-chlorooctane 614.35
    1-chlorotetradecane 262.31
    n-nonane 252.52
    undecane 172.82
    tert-butylcyclohexane 250.82
    cyclooctane 267.61
    cyclopentanol 706.78
    tetrahydropyran 1265.97
    tert-amyl methyl ether 559.57
    2,5,8-trioxanonane 556.2
    1-hexene 674.04
    2-isopropoxyethanol 321.75
    2,2,2-trifluoroethanol 249.5
    methyl butyrate 932.91

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction