2,2,2-Trifluoroethyl methacrylate

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  • Identifiers

    CAS number
    352-87-4

    Molecular formula
    C6H7F3O2

    SMILES
    CC(=C)C(=O)OCC(F)(F)F

    Safety labels

    Flammable
    Flammable

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 44.18%
    Sweet 31.2%
    Floral 20.79%
    Dry 20.65%
    Grape 19.73%
    Fruity 19.42%
    Savory 19.21%
    Milky 19.07%
    Citrus 18.83%
    Cooling 18.27%

     

    Flavor
    Odorless 35.2%
    Bitter 27.93%
    Bland 23.6%
    Mild 21.42%
    Sweet-like 19.49%
    Bread crust 19.31%
    Taco 19.17%
    Roasted 19.02%
    Orange flower 18.96%
    Soybean 18.94%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.7

    pKa est.
    4.32 (weak acid)

    Molecular weight
    168.11 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    111°C

    Flash point

    • 17.12 ˚C est.

  • Synonyms

    • 2,2,2-TRIFLUOROETHYL METHACRYLATE
    • 352-87-4
    • 2-Propenoic acid, 2-methyl-, 2,2,2-trifluoroethyl ester
    • DTXSID7059856
    • TFEMA
    • RefChem:80807
    • DTXCID0038962
    • 206-525-3
    • 2,2,2-trifluoroethyl 2-methylprop-2-enoate
    • Trifluoroethyl methacrylate
    • 2-Propenoic acid, 2-methyl-, trifluoroethyl ester
    • MFCD00013576
    • Methacrylic acid 2,2,2-trifluoroethyl ester
    • 2,2,2-Trifluoroethyl Methacrylate (stabilized with MEHQ)
    • 2,2,2-TRIFLUOROETHYLMETHACRYLATE
    • EINECS 206-525-3
    • NSC 32617
    • Methacrylic acid, 2,2,2-trifluoroethyl ester
    • SCHEMBL36595
    • 2-methyl-2-propenoic acid 2,2,2-trifluoroethyl ester
    • 2,2-Trifluoroethyl methacrylate
    • 2,2,2-trifluoroethyl-methacrylate
    • NSC32617
    • FD2010
    • MFCD00274739
    • NSC-32617
    • SBB088137
    • AKOS005063599
    • CS-W017819
    • AS-48910
    • FT104797
    • Methacrylic acid,2,2-trifluoroethyl ester
    • 2,2,2-Trifluoroethyl 2-methylacrylate #
    • DB-048768
    • M0738
    • NS00020641
    • EN300-7692027
    • A822708
    • F003325
    • 2,2,2-tris(fluoranyl)ethyl 2-methylprop-2-enoate
    • 2,2,2-Trifluoroethyl Methacrylate, (stabilized with MEHQ)
    • 2,2,2-Trifluoroethyl methacrylate, stab. w/ 100 ppm MEHQ
    • 2,2,2-Trifluoroethyl methacrylate 30-50ppm 4-Methoxyphenol as stabiliser
    • 2,2,2-Trifluoroethyl methacrylate, contains 100 ppm MEHQ as stabilizer, 98%
    • 2,2,2-Trifluoroethyl methacrylate, contains 50-200 ppm MEHQ as inhibitor, 99%
    • 352-87-4

  • Applications

    2,2,2-Trifluoroethyl methacrylate (CAS 352-87-4) is commonly used as a fluorinated methacrylate monomer to impart chemical resistance and weatherability to polymers via the trifluoroethyl group; in practice, it is often employed in protective coatings and paints to form low-surface-energy, solvent-resistant films; it is also used as a component in adhesives and sealants to improve adhesion and environmental performance; in addition, it participates in specialty polymers and copolymers to yield fluorinated polymers and protective films; it can serve as a reactive monomer in UV-curable systems to produce UV-cured coatings and inks; and as a surface-modifying monomer to create low-energy films for electronics and optics.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1591.62
    methanol 3101.81
    isopropanol 882.59
    water 54.79
    ethyl acetate 996.45
    n-propanol 820.81
    acetone 3094.49
    n-butanol 714.73
    acetonitrile 2007.16
    DMF 5915.83
    toluene 315.66
    isobutanol 573.31
    1,4-dioxane 1993.11
    methyl acetate 1484.06
    THF 3002.45
    2-butanone 1533.01
    n-pentanol 554.18
    sec-butanol 691.04
    n-hexane 56.01
    ethylene glycol 460.45
    NMP 3927.7
    cyclohexane 56.29
    DMSO 6335.65
    n-butyl acetate 530.72
    n-octanol 248.57
    chloroform 621.28
    n-propyl acetate 747.03
    acetic acid 1246.3
    dichloromethane 1411.5
    cyclohexanone 1072.98
    propylene glycol 355.03
    isopropyl acetate 577.13
    DMAc 3739.34
    2-ethoxyethanol 1709.96
    isopentanol 638.57
    n-heptane 50.3
    ethyl formate 1081.77
    1,2-dichloroethane 1162.17
    n-hexanol 333.54
    2-methoxyethanol 2744.94
    isobutyl acetate 310.55
    tetrachloromethane 75.74
    n-pentyl acetate 366.4
    transcutol 2305.86
    n-heptanol 184.8
    ethylbenzene 233.53
    MIBK 620.66
    2-propoxyethanol 986.38
    tert-butanol 1109.86
    MTBE 1060.31
    2-butoxyethanol 516.83
    propionic acid 589.13
    o-xylene 289.31
    formic acid 1266.45
    diethyl ether 1149.1
    m-xylene 224.29
    p-xylene 272.75
    chlorobenzene 315.23
    dimethyl carbonate 763.87
    n-octane 26.9
    formamide 3025.6
    cyclopentanone 1870.5
    2-pentanone 1103.22
    anisole 975.92
    cyclopentyl methyl ether 982.67
    gamma-butyrolactone 2324.18
    1-methoxy-2-propanol 1467.08
    pyridine 1180.71
    3-pentanone 779.08
    furfural 2264.91
    n-dodecane 26.61
    diethylene glycol 862.16
    diisopropyl ether 260.03
    tert-amyl alcohol 860.21
    acetylacetone 1429.38
    n-hexadecane 29.32
    acetophenone 865.45
    methyl propionate 1032.57
    isopentyl acetate 421.46
    trichloroethylene 1550.67
    n-nonanol 222.09
    cyclohexanol 418.51
    benzyl alcohol 622.6
    2-ethylhexanol 218.62
    isooctanol 149.47
    dipropyl ether 390.29
    1,2-dichlorobenzene 318.07
    ethyl lactate 354.47
    propylene carbonate 1042.33
    n-methylformamide 2859.77
    2-pentanol 456.74
    n-pentane 78.33
    1-propoxy-2-propanol 530.93
    1-methoxy-2-propyl acetate 585.56
    2-(2-methoxypropoxy) propanol 630.96
    mesitylene 150.98
    ε-caprolactone 1087.1
    p-cymene 153.12
    epichlorohydrin 2826.17
    1,1,1-trichloroethane 516.75
    2-aminoethanol 735.05
    morpholine-4-carbaldehyde 3348.08
    sulfolane 2523.63
    2,2,4-trimethylpentane 40.28
    2-methyltetrahydrofuran 1775.68
    n-hexyl acetate 534.34
    isooctane 28.06
    2-(2-butoxyethoxy)ethanol 868.49
    sec-butyl acetate 407.46
    tert-butyl acetate 714.95
    decalin 46.78
    glycerin 484.53
    diglyme 1887.95
    acrylic acid 670.15
    isopropyl myristate 232.96
    n-butyric acid 636.19
    acetyl acetate 658.4
    di(2-ethylhexyl) phthalate 208.58
    ethyl propionate 639.18
    nitromethane 4345.26
    1,2-diethoxyethane 879.26
    benzonitrile 636.29
    trioctyl phosphate 151.46
    1-bromopropane 490.35
    gamma-valerolactone 2724.27
    n-decanol 175.11
    triethyl phosphate 239.98
    4-methyl-2-pentanol 253.51
    propionitrile 825.97
    vinylene carbonate 954.02
    1,1,2-trichlorotrifluoroethane 1095.34
    DMS 612.22
    cumene 160.39
    2-octanol 148.08
    2-hexanone 744.49
    octyl acetate 301.76
    limonene 208.42
    1,2-dimethoxyethane 3121.82
    ethyl orthosilicate 221.3
    tributyl phosphate 218.08
    diacetone alcohol 861.46
    N,N-dimethylaniline 650.25
    acrylonitrile 1303.87
    aniline 461.62
    1,3-propanediol 896.59
    bromobenzene 278.42
    dibromomethane 738.8
    1,1,2,2-tetrachloroethane 903.29
    2-methyl-cyclohexyl acetate 352.74
    tetrabutyl urea 366.59
    diisobutyl methanol 144.06
    2-phenylethanol 411.74
    styrene 302.28
    dioctyl adipate 355.41
    dimethyl sulfate 1182.47
    ethyl butyrate 449.05
    methyl lactate 555.28
    butyl lactate 280.27
    diethyl carbonate 346.41
    propanediol butyl ether 447.05
    triethyl orthoformate 296.71
    p-tert-butyltoluene 148.05
    methyl 4-tert-butylbenzoate 546.95
    morpholine 2176.51
    tert-butylamine 572.42
    n-dodecanol 136.38
    dimethoxymethane 2890.06
    ethylene carbonate 725.26
    cyrene 789.39
    2-ethoxyethyl acetate 674.8
    2-ethylhexyl acetate 328.09
    1,2,4-trichlorobenzene 410.12
    4-methylpyridine 1433.49
    dibutyl ether 365.61
    2,6-dimethyl-4-heptanol 144.06
    DEF 1666.85
    dimethyl isosorbide 1090.41
    tetrachloroethylene 565.62
    eugenol 526.08
    triacetin 665.99
    span 80 392.52
    1,4-butanediol 423.59
    1,1-dichloroethane 703.33
    2-methyl-1-pentanol 469.87
    methyl formate 2501.13
    2-methyl-1-butanol 583.6
    n-decane 41.12
    butyronitrile 775.01
    3,7-dimethyl-1-octanol 255.63
    1-chlorooctane 149.67
    1-chlorotetradecane 72.49
    n-nonane 39.66
    undecane 32.75
    tert-butylcyclohexane 41.76
    cyclooctane 26.4
    cyclopentanol 577.45
    tetrahydropyran 1118.44
    tert-amyl methyl ether 843.5
    2,5,8-trioxanonane 1247.31
    1-hexene 199.54
    2-isopropoxyethanol 916.57
    2,2,2-trifluoroethanol 603.32
    methyl butyrate 928.7

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction