2,2'-Ethylidenebis(4,6-di-tert-butylphenol)

Overview IFRA Request a quote

  • Identifiers

    CAS number
    35958-30-6

    Molecular formula
    C30H46O2

    SMILES
    CC(C1=C(C(=CC(=C1)C(C)(C)C)C(C)(C)C)O)C2=C(C(=CC(=C2)C(C)(C)C)C(C)(C)C)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Woody 46.25%
    Phenolic 45.61%
    Leathery 39.71%
    Dry 36.44%
    Musk 31.3%
    Vetiver 30.47%
    Burnt 30.0%
    Camphoreous 29.12%
    Amber 28.27%
    Spicy 27.81%

     

    Flavor
    Camphor 40.0%
    Phenolic 35.84%
    Musty 32.03%
    Mild 29.93%
    Woody 26.2%
    Bitter 22.68%
    Creosote 21.9%
    Thymol 21.24%
    Green pepper 21.06%
    Eugenol 20.41%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    10.1

    pKa est.
    5.96 (weak acid)

    Molecular weight
    438.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    500°C

    Flash point

    • 177.0 ˚C est.

  • Synonyms

    • 35958-30-6
    • 2,2'-Ethylidenebis(4,6-di-tert-butylphenol)
    • tetrabutyl ethylidenebisphenol
    • Isonox 129
    • Vanox 1290
    • UNII-AY30042JFF
    • AY30042JFF
    • 1,1-bis(3,5-di-tert-butyl-2-hydroxyphenyl)ethane
    • DTXSID4038899
    • TINOGARD NOA
    • Ethylidenebisdibutylphenol
    • EINECS 252-816-3
    • DTXCID2018899
    • 2,2'-Ethylidene bis(4,6-di-t-butylphenol)
    • 2,2'-ethylidenebis[4,6-di-tert-butylphenol]
    • 2,2'-Ethylidenebis (4,5-di-tert.-butylphenol)
    • PHENOL, 2,2'-ETHYLLIDENEBIS(4,6-BIS(1,1-DIMETHYLETHYL)-
    • RefChem:80738
    • TETRABUTYL ETHYLIDENEBISPHENOL [INCI]
    • DXCHWXWXYPEZKM-UHFFFAOYSA-N
    • MFCD00075576
    • Phenol, 2,2'-ethylidenebis[4,6-bis(1,1-dimethylethyl)-
    • 2,4-ditert-butyl-6-[1-(3,5-ditert-butyl-2-hydroxyphenyl)ethyl]phenol
    • 6,6'-(Ethane-1,1-diyl)bis(2,4-di-tert-butylphenol)
    • 2,2'-Ethylidenebis(4,6-bis-tert-butylphenol)
    • Phenol, 2,2'-ethylidenebis(4,6-bis(1,1-dimethylethyl)-
    • 2,2-ethylidenebis(4,6-di-tert-butylphenol)
    • 2,4-bis(tert-butyl)-6-{[3,5-bis(tert-butyl)-2-hydroxyphenyl]ethyl}phenol
    • 2,2'-ethylidenebis(4,6-di-tert- butylphenol)
    • SCHEMBL27322
    • BIDD:ER0461
    • SCHEMBL8512816
    • CHEMBL3561026
    • Phenol,2,2'-ethylidenebis[4,6-bis(1,1-dimethylethyl)-
    • SCHEMBL30962428
    • Tox21_303979
    • SBB008130
    • AKOS015838552
    • MSK8729-1000M
    • NCGC00357203-01
    • AS-75843
    • 2,2'-Ethylidene bis(4,6,-di- t-butyl)
    • CAS-35958-30-6
    • DB-080919
    • 2,2'-ethylidene-bis(4,6-di-t-butylphenol)
    • bis-(3,5-di-t-butyl-2-hydroxyphenyl)ethane
    • NS00020805
    • ST50828231
    • 2,2'-Ethylidene-bis(4,6-di-tert-butylphenol)
    • 2,2'-ethylidenebis (4,6-di-tert-butylphenol)
    • A11726
    • F341982
    • 2,2'-ethane-1,1-diylbis(4,6-di-tert-butylphenol)
    • 2,2'-Ethylidene-bis(4,6-di-tert-butylphenol), 99%
    • Q27274185
    • 2,2'-(Ethane-1,1-diyl)bis(4,6-di-tert-butylphenol)
    • 2,4-ditert-butyl-6-[1-(3,5-ditert-butyl-2-hydroxy-phenyl)ethyl]phenol
    • 2,2'-Ethylidene-bis(4,6-di-tert-butylphenol) Solution in Methanol, 1000ug/mL
    • 35958-30-6

  • Applications

    2,2'-Ethylidenebis(4,6-di-tert-butylphenol) (CAS 35958-30-6) is a hindered phenolic antioxidant used primarily as a heat and oxidative stabilizer for polymer and rubber formulations in industrial settings. It helps improve the thermal and oxidative durability of polyolefin plastics such as polyethylene and polypropylene, engineering plastics, and rubber compounds. It is also used as a stabilizer in lubricants and process oils, as well as in coatings, inks, and adhesives to prevent oxidation during storage and use. Its role is that of an antioxidant/stabilizer in these applications, with use governed by local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 89.59
    methanol 36.57
    isopropanol 81.54
    water 0.1
    ethyl acetate 118.95
    n-propanol 108.53
    acetone 184.51
    n-butanol 99.25
    acetonitrile 49.91
    DMF 302.05
    toluene 128.74
    isobutanol 86.42
    1,4-dioxane 252.25
    methyl acetate 111.31
    THF 768.69
    2-butanone 199.31
    n-pentanol 111.72
    sec-butanol 107.2
    n-hexane 23.99
    ethylene glycol 9.55
    NMP 424.37
    cyclohexane 15.81
    DMSO 175.97
    n-butyl acetate 179.38
    n-octanol 87.75
    chloroform 317.78
    n-propyl acetate 143.92
    acetic acid 78.81
    dichloromethane 240.24
    cyclohexanone 292.86
    propylene glycol 42.9
    isopropyl acetate 111.45
    DMAc 303.1
    2-ethoxyethanol 146.23
    isopentanol 81.34
    n-heptane 22.95
    ethyl formate 85.94
    1,2-dichloroethane 148.55
    n-hexanol 120.8
    2-methoxyethanol 152.84
    isobutyl acetate 136.1
    tetrachloromethane 42.24
    n-pentyl acetate 190.5
    transcutol 246.18
    n-heptanol 113.23
    ethylbenzene 95.98
    MIBK 128.86
    2-propoxyethanol 214.87
    tert-butanol 97.88
    MTBE 129.78
    2-butoxyethanol 217.09
    propionic acid 76.18
    o-xylene 72.6
    formic acid 18.17
    diethyl ether 110.64
    m-xylene 97.1
    p-xylene 132.69
    chlorobenzene 153.24
    dimethyl carbonate 73.45
    n-octane 13.0
    formamide 38.64
    cyclopentanone 482.54
    2-pentanone 174.45
    anisole 166.84
    cyclopentyl methyl ether 260.0
    gamma-butyrolactone 423.46
    1-methoxy-2-propanol 181.69
    pyridine 278.28
    3-pentanone 120.16
    furfural 284.3
    n-dodecane 6.94
    diethylene glycol 83.44
    diisopropyl ether 48.58
    tert-amyl alcohol 113.48
    acetylacetone 199.12
    n-hexadecane 8.08
    acetophenone 161.05
    methyl propionate 122.41
    isopentyl acetate 186.79
    trichloroethylene 321.76
    n-nonanol 90.55
    cyclohexanol 93.95
    benzyl alcohol 118.55
    2-ethylhexanol 99.59
    isooctanol 103.4
    dipropyl ether 140.52
    1,2-dichlorobenzene 128.24
    ethyl lactate 80.95
    propylene carbonate 240.28
    n-methylformamide 98.52
    2-pentanol 81.71
    n-pentane 15.3
    1-propoxy-2-propanol 208.24
    1-methoxy-2-propyl acetate 198.89
    2-(2-methoxypropoxy) propanol 149.13
    mesitylene 54.78
    ε-caprolactone 270.67
    p-cymene 68.34
    epichlorohydrin 440.71
    1,1,1-trichloroethane 167.49
    2-aminoethanol 41.14
    morpholine-4-carbaldehyde 363.77
    sulfolane 466.37
    2,2,4-trimethylpentane 11.23
    2-methyltetrahydrofuran 367.28
    n-hexyl acetate 189.31
    isooctane 9.1
    2-(2-butoxyethoxy)ethanol 195.16
    sec-butyl acetate 114.84
    tert-butyl acetate 152.61
    decalin 18.48
    glycerin 44.91
    diglyme 309.28
    acrylic acid 61.71
    isopropyl myristate 81.35
    n-butyric acid 121.39
    acetyl acetate 81.15
    di(2-ethylhexyl) phthalate 88.85
    ethyl propionate 116.26
    nitromethane 143.21
    1,2-diethoxyethane 158.91
    benzonitrile 114.02
    trioctyl phosphate 67.99
    1-bromopropane 123.03
    gamma-valerolactone 559.48
    n-decanol 62.93
    triethyl phosphate 72.95
    4-methyl-2-pentanol 56.45
    propionitrile 69.3
    vinylene carbonate 176.58
    1,1,2-trichlorotrifluoroethane 223.82
    DMS 118.8
    cumene 70.4
    2-octanol 91.79
    2-hexanone 179.66
    octyl acetate 106.42
    limonene 83.63
    1,2-dimethoxyethane 256.62
    ethyl orthosilicate 78.89
    tributyl phosphate 70.48
    diacetone alcohol 167.29
    N,N-dimethylaniline 146.83
    acrylonitrile 74.83
    aniline 120.08
    1,3-propanediol 62.99
    bromobenzene 164.12
    dibromomethane 169.36
    1,1,2,2-tetrachloroethane 268.7
    2-methyl-cyclohexyl acetate 154.85
    tetrabutyl urea 104.24
    diisobutyl methanol 56.66
    2-phenylethanol 153.15
    styrene 99.37
    dioctyl adipate 119.2
    dimethyl sulfate 130.63
    ethyl butyrate 135.39
    methyl lactate 80.69
    butyl lactate 154.48
    diethyl carbonate 80.3
    propanediol butyl ether 167.14
    triethyl orthoformate 124.58
    p-tert-butyltoluene 70.49
    methyl 4-tert-butylbenzoate 197.11
    morpholine 331.68
    tert-butylamine 64.08
    n-dodecanol 44.01
    dimethoxymethane 194.11
    ethylene carbonate 139.53
    cyrene 199.74
    2-ethoxyethyl acetate 190.33
    2-ethylhexyl acetate 161.76
    1,2,4-trichlorobenzene 164.8
    4-methylpyridine 272.19
    dibutyl ether 105.22
    2,6-dimethyl-4-heptanol 56.66
    DEF 165.97
    dimethyl isosorbide 331.1
    tetrachloroethylene 128.83
    eugenol 183.46
    triacetin 156.14
    span 80 166.69
    1,4-butanediol 40.02
    1,1-dichloroethane 155.52
    2-methyl-1-pentanol 99.15
    methyl formate 83.88
    2-methyl-1-butanol 91.42
    n-decane 15.46
    butyronitrile 87.87
    3,7-dimethyl-1-octanol 77.12
    1-chlorooctane 64.75
    1-chlorotetradecane 22.16
    n-nonane 14.84
    undecane 9.83
    tert-butylcyclohexane 21.97
    cyclooctane 8.62
    cyclopentanol 141.92
    tetrahydropyran 272.05
    tert-amyl methyl ether 110.65
    2,5,8-trioxanonane 192.46
    1-hexene 80.78
    2-isopropoxyethanol 129.79
    2,2,2-trifluoroethanol 33.06
    methyl butyrate 156.77

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction