2,2'-Ethylenedioxydiethyl bis(2-ethylhexanoate)

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  • Identifiers

    CAS number
    94-28-0

    Molecular formula
    C22H42O6

    SMILES
    CCCCC(CC)C(=O)OCCOCCOCCOC(=O)C(CC)CCCC

    Safety labels

  • Odor profile

    Fragrance
    Fruity 60.24%
    Oily 41.68%
    Fatty 33.69%
    Herbal 31.2%
    Peach 29.21%
    Lactonic 27.75%
    Fresh 25.19%
    Buttery 24.97%
    Odorless 23.19%
    Waxy 22.75%

     

    Flavor
    Fruity 65.65%
    Waxy 55.88%
    Green 40.14%
    Oily 36.64%
    Fatty 34.83%
    Creamy 33.5%
    Sweet 33.26%
    Apple 32.66%
    Wine 32.62%
    Tropical 31.7%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.4

    pKa est.
    5.71 (weak acid)

    Molecular weight
    402.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    412°C

    Flash point

    • 176.52 ˚C est.

  • Synonyms

    • 2,2'-Ethylenedioxydiethyl bis(2-ethylhexanoate)
    • Hexanoic acid, 2-ethyl-, 1,2-ethanediylbis(oxy-2,1-ethanediyl) ester
    • Hexanoic acid, 2-ethyl-, 1,1'-(1,2-ethanediylbis(oxy-2,1-ethanediyl)) ester
    • Hexanoic acid, 2-ethyl-, 1,1'-[1,2-ethanediylbis(oxy-2,1-ethanediyl)] ester
    • RefChem:440300
    • 94-28-0
    • TRIETHYLENE GLYCOL BIS(2-ETHYLHEXANOATE)
    • Flexol 3GO
    • Flexol plasticizer 3GO
    • 2-[2-[2-(2-ethylhexanoyloxy)ethoxy]ethoxy]ethyl 2-ethylhexanoate
    • (Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(2-ethylhexanoate)
    • MFCD00072285
    • ethane-1,2-diylbis(oxyethane-2,1-diyl) bis(2-ethylhexanoate)
    • Triethylene glycol di(2-ethylhexoate)
    • Triethylene glycol, bis(2-ethylhexanoate)
    • Hexanoic acid, 2-ethyl-, diester with triethylene glycol
    • Tri(ethylene glycol) bis(2-ethylhexanoate)
    • GE16EV367Q
    • DTXSID3026564
    • DTXCID006564
    • CAS-94-28-0
    • EINECS 202-319-2
    • BRN 1806809
    • UNII-GE16EV367Q
    • AI3-01451
    • Kodaflex TEG-EH
    • Flexol 3 GO
    • Tri(ethylenglycol)bis-2-ethylhexanoate
    • EC 202-319-2
    • TEG (EH)
    • TEGMER 803
    • SCHEMBL32980
    • CHEMBL3185676
    • CHEBI:189116
    • Tox21_202276
    • Tox21_300309
    • FT30203
    • Triethylene glycol, bis(ethylhexanoate)
    • triethyleneglycol bis(2-ethylhexanoate)
    • triethylene glycol di(2-ethylhexanoate)
    • MSK161932-1000B
    • NCGC00164193-01
    • NCGC00164193-02
    • NCGC00164193-03
    • NCGC00254146-01
    • NCGC00259825-01
    • tri(ethyleneglycol)bis(2-ethylhexanoate)
    • BS-42438
    • SY066780
    • NS00010080
    • Triethylene glycol, bis[2-ethylhexyl] ester
    • TRIETHYLENE GLYCOL DI-2-ETHYLHEXANOATE
    • F77942
    • Tri(ethylene glycol) bis(2-ethylhexanoate), 97%
    • W-109350
    • Hexanoic acid, ethyl-, diester with triethylene glycol
    • Q27279058
    • Ethane, 1,2-(2'-hydroxyethoxy)-, di-(2-ethylhexanoate)-
    • Ethane-1,2-diylbis(oxyethane-2,1-diyl)bis(2-ethylhexanoate)
    • TRIETHYLENE GLYCOL 2-ETHYLHEXANOIC ACID DIESTER (1:2)
    • [(Ethane-1,2-diyl)bis(oxy)ethane-2,1-diyl] bis(2-ethylhexanoate)
    • (Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl)bis(2-ethylhexanoate)
    • 2-(2-(2-[(2-Ethylhexanoyl)oxy]ethoxy)ethoxy)ethyl 2-ethylhexanoate #
    • Triethylene glycol bis(ethylhexanoate) Solution in Acetone, 1000ug/mL
    • HEXANOIC ACID, 2-ETHYL-, 1,2-ETHANEDIYLBIS(OXY-2,1- ETHANEDIYL) ESTER
    • 202-319-2
    • 94-28-0

  • Applications

    2,2'-Ethylenedioxydiethyl bis(2-ethylhexanoate), CAS 94-28-0, is commonly used as a plasticizer for polymers, particularly PVC and other resins, to enhance flexibility and processability. It is also employed in coatings and inks as a plasticizing additive to improve film formation and mechanical properties. In adhesives and sealants, it acts as a plasticizer to adjust tack, viscosity, and performance. It can be incorporated into elastomer formulations to tune softness and elongation. In cosmetics and personal care, it may serve as an emollient and conditioning ingredient in certain formulations, subject to regulatory limits. Additionally, as a diester, it can function as an intermediate in organic synthesis or be evaluated as a non-phthalate alternative in some applications, depending on regulatory and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 46.95
    methanol 72.4
    isopropanol 42.84
    water 1.13
    ethyl acetate 384.3
    n-propanol 67.22
    acetone 325.87
    n-butanol 60.78
    acetonitrile 188.93
    DMF 295.82
    toluene 217.01
    isobutanol 63.01
    1,4-dioxane 393.26
    methyl acetate 293.38
    THF 645.32
    2-butanone 320.44
    n-pentanol 63.71
    sec-butanol 79.75
    n-hexane 17.69
    ethylene glycol 9.16
    NMP 969.95
    cyclohexane 116.54
    DMSO 523.56
    n-butyl acetate 206.17
    n-octanol 58.96
    chloroform 1410.17
    n-propyl acetate 270.64
    acetic acid 282.08
    dichloromethane 1765.05
    cyclohexanone 939.72
    propylene glycol 15.93
    isopropyl acetate 253.98
    DMAc 666.47
    2-ethoxyethanol 155.96
    isopentanol 68.8
    n-heptane 12.96
    ethyl formate 176.52
    1,2-dichloroethane 1019.02
    n-hexanol 44.26
    2-methoxyethanol 149.87
    isobutyl acetate 143.08
    tetrachloromethane 300.7
    n-pentyl acetate 325.63
    transcutol 515.86
    n-heptanol 54.0
    ethylbenzene 100.56
    MIBK 170.82
    2-propoxyethanol 119.01
    tert-butanol 71.66
    MTBE 133.68
    2-butoxyethanol 148.29
    propionic acid 192.19
    o-xylene 176.85
    formic acid 82.15
    diethyl ether 152.36
    m-xylene 124.16
    p-xylene 154.51
    chlorobenzene 398.0
    dimethyl carbonate 127.54
    n-octane 9.11
    formamide 169.96
    cyclopentanone 844.12
    2-pentanone 279.33
    anisole 173.39
    cyclopentyl methyl ether 380.7
    gamma-butyrolactone 970.9
    1-methoxy-2-propanol 117.54
    pyridine 552.85
    3-pentanone 314.62
    furfural 745.08
    n-dodecane 6.23
    diethylene glycol 70.9
    diisopropyl ether 58.4
    tert-amyl alcohol 113.28
    acetylacetone 439.23
    n-hexadecane 7.34
    acetophenone 285.36
    methyl propionate 284.05
    isopentyl acetate 187.77
    trichloroethylene 1754.22
    n-nonanol 57.99
    cyclohexanol 205.7
    benzyl alcohol 143.04
    2-ethylhexanol 50.49
    isooctanol 54.24
    dipropyl ether 88.89
    1,2-dichlorobenzene 447.8
    ethyl lactate 102.24
    propylene carbonate 489.67
    n-methylformamide 165.5
    2-pentanol 52.8
    n-pentane 14.28
    1-propoxy-2-propanol 102.26
    1-methoxy-2-propyl acetate 194.37
    2-(2-methoxypropoxy) propanol 137.31
    mesitylene 81.8
    ε-caprolactone 814.38
    p-cymene 61.93
    epichlorohydrin 964.07
    1,1,1-trichloroethane 881.43
    2-aminoethanol 27.74
    morpholine-4-carbaldehyde 528.34
    sulfolane 1329.54
    2,2,4-trimethylpentane 17.25
    2-methyltetrahydrofuran 523.01
    n-hexyl acetate 273.33
    isooctane 6.43
    2-(2-butoxyethoxy)ethanol 169.18
    sec-butyl acetate 188.62
    tert-butyl acetate 262.54
    decalin 35.52
    glycerin 35.6
    diglyme 453.5
    acrylic acid 177.9
    isopropyl myristate 74.34
    n-butyric acid 287.15
    acetyl acetate 332.87
    di(2-ethylhexyl) phthalate 86.69
    ethyl propionate 250.96
    nitromethane 638.4
    1,2-diethoxyethane 223.84
    benzonitrile 230.79
    trioctyl phosphate 62.32
    1-bromopropane 343.33
    gamma-valerolactone 1045.62
    n-decanol 36.51
    triethyl phosphate 129.05
    4-methyl-2-pentanol 36.15
    propionitrile 143.19
    vinylene carbonate 444.77
    1,1,2-trichlorotrifluoroethane 566.8
    DMS 230.73
    cumene 63.84
    2-octanol 49.36
    2-hexanone 212.39
    octyl acetate 107.09
    limonene 98.16
    1,2-dimethoxyethane 311.02
    ethyl orthosilicate 117.57
    tributyl phosphate 85.38
    diacetone alcohol 199.38
    N,N-dimethylaniline 123.3
    acrylonitrile 188.72
    aniline 189.03
    1,3-propanediol 50.73
    bromobenzene 487.18
    dibromomethane 1009.77
    1,1,2,2-tetrachloroethane 1278.12
    2-methyl-cyclohexyl acetate 173.26
    tetrabutyl urea 116.11
    diisobutyl methanol 33.59
    2-phenylethanol 99.86
    styrene 132.09
    dioctyl adipate 150.08
    dimethyl sulfate 296.05
    ethyl butyrate 206.14
    methyl lactate 105.81
    butyl lactate 170.58
    diethyl carbonate 143.2
    propanediol butyl ether 106.03
    triethyl orthoformate 150.8
    p-tert-butyltoluene 53.25
    methyl 4-tert-butylbenzoate 230.87
    morpholine 435.62
    tert-butylamine 49.24
    n-dodecanol 25.27
    dimethoxymethane 202.56
    ethylene carbonate 399.34
    cyrene 217.96
    2-ethoxyethyl acetate 373.44
    2-ethylhexyl acetate 169.24
    1,2,4-trichlorobenzene 540.4
    4-methylpyridine 470.28
    dibutyl ether 101.88
    2,6-dimethyl-4-heptanol 33.59
    DEF 409.73
    dimethyl isosorbide 304.78
    tetrachloroethylene 1020.38
    eugenol 171.81
    triacetin 345.96
    span 80 129.85
    1,4-butanediol 31.72
    1,1-dichloroethane 669.92
    2-methyl-1-pentanol 77.16
    methyl formate 143.91
    2-methyl-1-butanol 80.63
    n-decane 12.83
    butyronitrile 139.57
    3,7-dimethyl-1-octanol 55.84
    1-chlorooctane 70.39
    1-chlorotetradecane 21.66
    n-nonane 12.14
    undecane 8.26
    tert-butylcyclohexane 20.32
    cyclooctane 26.81
    cyclopentanol 198.44
    tetrahydropyran 452.13
    tert-amyl methyl ether 150.32
    2,5,8-trioxanonane 251.91
    1-hexene 56.38
    2-isopropoxyethanol 121.61
    2,2,2-trifluoroethanol 200.48
    methyl butyrate 340.48

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction